Waukulu >> Mankhwala Osokoneza Bongo Vs. Mnzanu >> Trintellix vs. Zoloft: Kusiyana, kufanana, ndi zomwe zili zabwino kwa inu

Trintellix vs. Zoloft: Kusiyana, kufanana, ndi zomwe zili zabwino kwa inu

Mankhwala osokoneza bongo Vs. Mnzanu

Trintellix ndi Zoloft ndi njira ziwiri zochiritsira chimodzi mwazovuta zamatenda ku America, vuto lalikulu lachisoni. Matenda akulu okhumudwa (MDD) amadziwika ndi nthawi yosachepera milungu iwiri pomwe wodwala amakhala ndi nkhawa kapena kutaya chidwi ndi zinthu zomwe zimabweretsa chisangalalo. MDD imatha kuyambitsa mavuto ena azaumoyo. Zitha kupanganso mavuto ndi kugona, kudya, kusinkhasinkha, ndi mphamvu.

Trintellix (vortioxetine) imawerengedwa kuti ndi serotonin modulator ndi stimulator ndipo ndiopatsa pharmacologically poyerekeza ndi mankhwala ena opatsirana pogonana. Zoloft (sertraline) ndi serotonin reuptake inhibitor (SSRI) yosankha ndipo imakhala m'gulu lomwelo la anti-depressants monga mankhwala monga Prozac (fluoxetine), Paxil (paroxetine), Celexa (citalopram), ndi Lexapro (escitalopram).

Kodi pali kusiyana kotani pakati pa Trintellix ndi Zoloft?

Trintellix ndi mankhwala akuchipatala omwe amawonetsedwa pochiza vuto lalikulu lachisoni. Amadziwika kuti serotonin modulator ndi stimulator, ndikupangitsa kuti ikhale yosiyana ndi mankhwala ena opatsirana pakadali pano. Ngakhale magwiridwe antchito enieniwo ndi ovuta kudzipatula, amaganiza kuti amachulukitsa ntchito ya serotonin kudzera poletsa wotumiza wa serotonin mu neuron synapse. Awonetsedwa kuti amaletsa ma serotonin receptors angapo, komanso amalimbikitsanso cholandilira chimodzi, 5-HT1A. Magulu apamwamba a serotonin omwe amapezeka amapezeka chifukwa cha kusintha kwamaganizidwe ndi mphamvu.

Trintellix poyamba adabweretsedwa kumsika pansi pa dzina la malonda Brintellix, koma kuda nkhawa ndi zolakwika zomwe zingachitike chifukwa cha kufanana kwa magazi kwa wowonda magazi Brilanta adatsogolera FDA kusintha dzina lake mu Juni wa 2016. Trintellix imapezeka ngati piritsi lamlomo mwamphamvu za 5 mg, 10 mg, ndi 20 mg.

Zoloft, ndi mawonekedwe ake achibadwa sertraline, ndi mankhwala akuchipatala omwe amawonetsedwa pochiza kukhumudwa. Zoloft amadziwika kuti ndi serotonin reuptake inhibitor yosankha ndipo imagwira ntchito poletsa kubwezeretsanso kwa serotonin pa neuronal synapse.

Zoloft imapezeka ngati piritsi yamlomo pamphamvu za 25 mg, 50 mg, ndi 100 mg. Ikupezekanso mu yankho lokhazikika pakamwa lomwe ndi 20 mg / ml.

Kusiyana kwakukulu pakati pa Trintellix vs. Zoloft
	Zamgululi	Zoloft
Gulu la mankhwala osokoneza bongo	Serotonin modulator ndi stimulator	Kusankha serotonin reuptake inhibitor
Chizindikiro cha Brand / generic	Zopezeka zokha	Zolemba ndi generic zilipo
Kodi dzina lachibadwa ndi liti?	Vortioxetine	Sertraline
Kodi mankhwalawa amabwera mwa mawonekedwe ati?	Piritsi lapakamwa	Piritsi lapakamwa, yankho lokhazikika pakamwa
Kodi mulingo woyenera ndi uti?	20 mg tsiku lililonse	50 mg tsiku lililonse
Kodi mankhwalawa amatenga nthawi yayitali bwanji?	Miyezi mpaka zaka	Miyezi mpaka zaka
Ndani amagwiritsa ntchito mankhwalawa?	Akuluakulu	Ana ndi achinyamata

Zinthu zomwe Trintellix vs. Zoloft adachita

Trintellix imangokhala ndi chiwonetsero chimodzi chovomerezeka, vuto lalikulu lachisoni. Zoloft amawonetsedwanso pochiza vuto lalikulu lachisoni, koma amagwiritsanso ntchito zina zingapo.

Zoloft imavomerezedwa pochiza matenda osokoneza bongo komanso nkhawa zamagulu. Amavomerezanso kuthana ndi matenda amantha komanso mantha pambuyo pa zoopsa (PTSD). Zoloft ili ndi ntchito zambiri zomwe sizinavomerezedwe ndi Food and Drug Administration (FDA). Izi zomwe amagwiritsidwa ntchito pamaguluwa zimaphatikizapo matenda amisala (GAD), matenda opatukana, kupsa mtima komwe kumakhudzana ndi kusamba kwa thupi, komanso kutaya msanga msanga.

Tebulo lotsatirali limatchula zina mwazomwe Trintellix ndi Zoloft amagwiritsa ntchito. Ndi dokotala wanu yekhayo amene angasankhe mankhwala omwe angakhale oyenera matenda anu.

Mkhalidwe	Zamgululi	Zoloft
Kusokonezeka kwakukulu	Inde	Inde
Matenda osokoneza bongo (OCD)	Ayi	Inde
Matenda amisala	Ayi	Inde
Matenda amisala wamba	Ayi	Kutumiza
Matenda akudzipatula	Ayi	Kutumiza
Kusokonezeka kwamantha	Ayi	Inde
Post-traumatic stress disorder	Ayi	Inde
Kutentha kotentha komwe kumakhudzana ndi kusintha kwa thupi	Ayi	Kutumiza
Kuthamangira msanga	Ayi	Kutumiza
Matenda a Premenstrual dysphoric (PMDD)	Ayi	Inde

Kodi Trintellix kapena Zoloft ndi yothandiza kwambiri?

Ochita kafukufuku adayesa kuyerekezera kuthekera ndi kulekerera kwa mankhwala opatsirana pogonana kwambiri. Kuchepetsa mitengo ya mankhwala opanikizika amitundumitundu kungakhale chifukwa chodandaulira pamene othandizira azaumoyo akusankha njira zochiritsira odwala awo.

KU kusanthula meta poyerekeza antidepressants angapo mu magwiridwe antchito ndi kulolerana. Zosakaniza za Trintellix ndi Zoloft zinaphatikizidwa. Ochita kafukufuku anapeza kuti mankhwala onse opatsirana pogonana anali othandiza kwambiri kuposa maloboti. Trintellix inaphatikizidwa pamndandanda wa mankhwala opatsirana pogwira ntchito kuposa ena, pomwe Zoloft sanali. Komabe, mankhwala onsewa anapezeka kuti ndi ena mwa mankhwala ochepetsa matenda opatsirana pogonana, zomwe zimapangitsa kuti anthu asiye kusiya.

Osiyana kusanthula kwazolemba anayang'ana Trintellix ngati chithandizo chachiwiri kwa iwo omwe amalephera kukhala ndi mayankho okwanira ku SSRI ngati Zoloft. Kuwunikaku kunayesa odwala omwe sanayankhe bwino kuchipatala chimodzi ndi SSRI ndipo adasinthidwa kupita kuchipatala. Omwe asintha kupita ku Trintellix adawona kukhululukidwa kwakukulu poyerekeza ndi mankhwala ena.

Trintellix ikuwoneka ngati yofananako, ngati siyabwino kuposa, ma SSRIs ngati Zoloft. Kulekerera kwamankhwala onsewa kumakhala koyenera poyerekeza ndi mankhwala ena opatsirana pogonana. Ndi omwe amakupatsani chithandizo chamankhwala okha omwe angasankhe mankhwala omwe angakhale oyenera kwa inu.

Kuwerengera ndi kuwerengera mtengo kwa Trintellix vs. Zoloft

Trintellix ndi mankhwala omwe amalembedwa ndi Medicare komanso mapulani a inshuwaransi yamalonda. Mtengo wamthumba wa mwezi umodzi wa Trintellix 20 mg utha kukhala wokwera $ 660. Ndi coupon yochokera ku SingleCare, mutha kulipira ndalama zosakwana $ 400.

Zoloft ndi mankhwala omwe amalembedwa ndi Medicare komanso mapulani azamalonda. Mtengo wapa thumba wa dzina lake Zoloft utha kukhala wokwana $ 105, koma ndi coupon yochokera ku SingleCare, mutha kulipira $ 10 ya generic.

	Zamgululi	Zoloft
Nthawi zambiri amakhala ndi inshuwaransi?	Inde	Inde
Nthawi zambiri amakhala ndi Medicare Part D?	Inde	Inde
Mlingo woyenera	30, 20 mg mapiritsi	30, 50 mg mapiritsi
Wopanga Medicare wamba	Zosintha kutengera pulani	$ 10 kapena zochepa
Mtengo wosakwatiwa	$ 357	$ 10

Zotsatira zoyipa za Trintellix vs. Zoloft

Trintellix ndi Zoloft iliyonse imakhudza serotonin njira, chifukwa chake zotulukapo zake zimakhala zofanana koma zimatha kupezeka pafupipafupi. Iliyonse ya mankhwalawa imatha kuyambitsa zovuta zam'mimba monga nseru, kusanza, kutsegula m'mimba, ndi / kapena kudzimbidwa. Nausea imapezeka mwa odwala 1 mwa atatu omwe amatenga Trintellix, ndipo 1 mwa odwala anayi amatenga Zoloft.

Zoloft akuti amachititsa kuti azisangalala ndi 11% ya odwala omwe akuwatenga, pomwe mabuku a Trintellix sanena kuti kusungulumwa kungachitike.

Kulephera kugonana kumawoneka kuti kukuchitika kwambiri ndi Trintellix poyerekeza ndi Zoloft, 30-35% motsutsana ndi 6% motsatana. Zotsatira zakugonana ndizofunikira kuziganizira chifukwa zimatha kupangitsa odwala kusiya mankhwalawa. Palibe mankhwala omwe amanenanso kuti achepetsa kapena kulemera.

Mndandanda wotsatirawu sikuti ukhale mndandanda wathunthu wazomwe zikuchitika. Chonde funsani wamankhwala, dokotala, kapena katswiri wina wazachipatala kuti mupeze mndandanda wazomwe zingachitike.

	Zamgululi	Zoloft
Zotsatira zoyipa	Zoyenera?	Pafupipafupi	Zoyenera?	Pafupipafupi
Nseru	Inde	32%	Inde	26%
Pakamwa pouma	Inde	8%	Inde	14%
Kutuluka thukuta	Ayi	n / A	Inde	7%
Kutsekula m'mimba	Inde	7%	Inde	makumi awiri%
Kudzimbidwa	Inde	6%	Inde	6%
Dyspepsia	Ayi	n / A	Inde	8%
Kusanza	Inde	6%	Inde	4%
Chizungulire	Inde	9%	Inde	12%
Kusinza	Ayi	n / A	Inde	khumi ndi chimodzi%
Maloto achilendo	Inde	3%	Ayi	n / A
Pruritus	Inde	3%	Ayi	n / A
Kuchepetsa chilakolako	Ayi	n / A	Inde	3%
Kudzikweza	Inde	1%	Ayi	n / A
Kuchepetsa libido	Inde	30-35%	Inde	6%

Gwero: Trintellix ( Tsiku ndi Tsiku Zoloft ( Tsiku ndi Tsiku )

Kuyanjana kwa mankhwala a Trintellix vs. Zoloft

Kugwiritsiridwa ntchito kwa Trintellix kapena Zoloft wokhala ndi monoamine oxidase inhibitors kumatha kubweretsa kuchuluka kwa matenda a serotonin. Matenda a Serotonin amadziwika ndi kukhumudwa, chizungulire, kapena kuchuluka kwa mtima kapena kuthamanga kwa magazi. Izi zimachitika pakakhala serotonin yayikulu mthupi. Mankhwala ena omwe angayambitse matenda a serotonin akagwiritsidwa ntchito ndi Trintellix kapena Zoloft ndi monga fentanyl, lithiamu, tramadol, buspirone, ndi St. John's Wort.

Zoloft amatha kulumikizana ndi mitundu ingapo ya mankhwala ndikupangitsa mtundu wina wamatenda amtima omwe amadziwika kuti ndi nthawi yayitali ya QTc. Izi zitha kuchitika ndi maantibayotiki omwe amagwiritsidwa ntchito monga erythromycin kapena gatifloxacin. Zitha kukhalanso ndi ma antipsychotic monga ziprasidone kapena chlorpromazine. Ndikofunika kuti wolembera wanu adziwe mndandanda wathunthu wamankhwala asanakupatseni mankhwala atsopano.

Mndandanda wotsatirawu sikuti ukhale mndandanda wathunthu wamagwiritsidwe azamankhwala. Ndibwino kuti mufunsane ndi omwe amakupatsirani kapena wamankhwala kuti mupeze mndandanda wathunthu.

Mankhwala osokoneza bongo	Gulu la mankhwala osokoneza bongo	Zamgululi	Zoloft
Selegiline Phenelzine Mzere Isocarboxazid	Monoamine oxidase inhibitors (MAOIs)	Inde	Inde
Citalopram Kuyanjana Fluoxetine Paroxetine	Kusankha serotonin reuptake inhibitors (SSRIs)	Inde	Inde
Chotsani Katemera Duloxetine Khalidwe	Kusankha norepinephrine reuptake inhibitors (SNRIs)	Inde	Inde
Amitriptyline Desipramine Doxepin Imipramine Mzere wa Nortriptyline	Tricyclic antidepressants	Inde	Inde
Almotriptan Eletriptan Frovatriptan Naratriptan Rizatriptan Sumatriptan Zolmitriptan	Zolemba	Inde	Inde
Clopidogrel Heparin Warfarin	Ma Platelet inhibitors	Inde	Inde
Asipilini	Mankhwala osagwiritsidwa ntchito poletsa kutupa (NSAIDs)	Inde	Inde
Phenytoin	Anti-khunyu	Ayi	Inde
Ziprasidone Zamgululi Chlorpromazine Droperidol	Ma anti-psychotic	Ayi	Inde
Mankhwalawa Gatifloxacin Moxifloxacin	Maantibayotiki	Ayi	Inde
Quinidine Procainamide Amiodarone Sotalol	Zosokoneza	Ayi	Inde

Machenjezo a Trintellix vs. Zoloft

Odwala omwe ali ndi vuto lalikulu la kukhumudwa atha kukhala ndi vuto lakukhumudwa kapena malingaliro ofuna kudzipha kapena popanda chithandizo ndi mankhwala akuchipatala monga Trintellix kapena Zoloft. Zizindikirozi zimatha kukulira mpaka kukhululukidwa kwa MDD kukwaniritsidwa. Trintellix ndi Zoloft zitha kubweretsa malingaliro ofuna kudzipha mwa achinyamata ndi achinyamata, makamaka kumayambiriro kwa chithandizo. Odwalawa ayenera kuyang'aniridwa mosamala, ndipo kusintha kwa mankhwala kungakhale kofunikira ngati zizindikiro zatsopano zayamba kapena zikuipiraipira.

Ndikofunika kukumbukira kuti mankhwala monga Trintellix ndi Zoloft samabweretsa kukhululukidwa kwazizindikiro. Zitha kutenga masabata osachepera awiri kuti muwone kusintha kwamtundu uliwonse, mpaka milungu inayi mpaka isanu ndi umodzi kuti muwone momwe mankhwalawa amathandizira. Ndikofunikira kuti odwala amvetsetse ndandanda iyi kuti asaleke kumwa mankhwala asanakwane.

Matenda a Serotonin, omwe amayamba chifukwa cha serotonin, amatha kuchitika ndi Trintellix ndi Zoloft. Zitha kupangitsa kusokonezeka, chizungulire, ndikupangitsa kugunda kwamtima.

Trintellix iyenera kugwiritsidwa ntchito mosamala kwa odwala omwe ali ndi mbiri kapena mbiri yamabanja ya mania, hypomania, kapena matenda ochititsa munthu kusinthasintha zochitika. Trintellix amadziwika kuti amachititsa mania ndi hypomania episodes kwa odwala omwe amamwa chifukwa cha kuvutika maganizo.

Mafunso omwe amafunsidwa kawirikawiri za Trintellix vs. Zoloft

Kodi Trintellix ndi chiyani?

Trintellix ndi mankhwala ochepetsa kupanikizika omwe amagwiritsidwa ntchito pochiza matenda osokoneza bongo. Trintellix ndi yapadera chifukwa ndi serotonin modulator ndi stimulator. Trintellix imapezeka m'mapiritsi apakamwa mu 5 mg, 10 mg, ndi 20 mg mphamvu.

Kodi Zoloft ndi chiyani?

Zoloft ndi mankhwala ochepetsa kupsinjika mtima omwe amagwiritsidwa ntchito pochiza matenda opsinjika mtima komanso zovuta zina komanso matenda amisala. Zoloft ali mgulu la mankhwala omwe amadziwika kuti serotonin reuptake inhibitors (SSRIs). Zoloft imapezeka ngati mapiritsi apakamwa mu 25 mg, 50 mg, ndi mphamvu za 100 mg, komanso kutsekemera kwamadzi am'kamwa.

Kodi Trintellix ndi Zoloft ndi ofanana?

Ngakhale onse a Trintellix ndi Zoloft ali ndi vuto lalikulu lachisoni powonjezera serotonin yomwe ilipo, amatero m'mafashoni osiyana ndipo chifukwa chake si mankhwala omwewo.

Kodi Trintellix kapena Zoloft ndibwino?

Ngakhale kuti Trintellix ndi Zoloft ndizovuta kupeweratu kupsinjika poyerekeza ndi mankhwala ofanana, kafukufuku wina wazachipatala akuwonetsa kuti Trintellix ikhoza kukhala njira yabwino kwambiri kwa odwala omwe alephera kale mankhwala a SSRIs monga Zoloft.

Kodi nditha kugwiritsa ntchito Trintellix kapena Zoloft ndili ndi pakati?

Food and Drug Administration (FDA) imaganizira gulu lonse la pakati la Trintellix ndi Zoloft C, kutanthauza kuti sipanakhale maphunziro okwanira aanthu kuti athetse chitetezo. Mwambiri, mankhwala aliwonse ayenera kugwiritsidwa ntchito pokhapokha phindu kwa mayi limaposa chiopsezo cha mwana wosabadwayo.

Kodi ndingagwiritse ntchito Trintellix kapena Zoloft ndi mowa?

Mowa umatha kuwonjezera zoopsa za Trintellix ndi Zoloft. Kumwa mowa ndikumwa mankhwalawa kumatha kuyambitsa vuto lalikulu la psychomotor, ndipo pachifukwa ichi, odwala amalangizidwa kuti apewe kumwa mowa ngati atamwa mankhwalawa.

Kodi Trintellix imathandizira nkhawa?

Trintellix sichiwonetsedwa kuti ithetse vuto lililonse lamatenda.

Kodi Trintellix imasiyana bwanji ndi ma SSRIs ena?

Trintellix ndi serotonin modulator komanso yotulutsa. Izi zimathandizira kupanga serotonin yaulere yotsogola yomwe imapangitsa kuti mukhale osangalala komanso kuchepa kwazizindikiro.