Waukulu >> Zambiri Zamankhwala >> Kodi calcium channel blockers ndi chiyani?

Kodi calcium channel blockers ndi chiyani?

Mankhwala Osokoneza bongo a calcium Info, monga amlodipine ndi felodipine, amachepetsa kuthamanga kwa magazi ndikuchiza matenda ena amtima

Ngati inu kapena wokondedwa muli ndi mkulu kuthamanga kwa magazi kapena matenda amtima, mwina mudamvapo zamankhwala ngati okodzetsa , zotchinga beta , Zoletsa za ACE , ARBs (angiotensin II receptor blockers), ndi calcium channel blockers.

Ma calcium channel blockers (omwe amadziwikanso kuti CCBs mwachidule) ndi gulu la mankhwala oletsa kuthamanga kwa magazi omwe amagwiritsidwa ntchito pochiza matenda osiyanasiyana, monga kuthamanga kwa magazi. M'malo mwake, CCB yotchedwa amlodipine ndi imodzi mwamankhwala omwe amadziwika kwambiri ndi mzinda ndipo boma . Amlodipine analinso mankhwala achitatu otchuka kwambiri pakati pa ogwiritsa ntchito a SingleCare mu 2020.

Pitirizani kuwerenga kuti mudziwe zambiri za CCBs, kuphatikizapo zomwe amagwiritsidwa ntchito, zotsatira zake, ndi chidziwitso cha chitetezo.

Mndandanda wama calcium blockers
Dzina Brand (dzina generic)	Avereji ya ndalama	Kusungidwa kwa SingleCare	Dziwani zambiri
Khalan, Isoptin, Verelan (verapamil)	$ 74 pa 100, mapiritsi a 120 mg otulutsidwa	Pezani ma coupon a verapamil	Zambiri za Verapamil
Cardene (nicardipine)	$ 946 ya 90, 20 mg makapisozi	Pezani makuponi a nicardipine	Zambiri za Nicardipine
Cardizem, Tiazac, Dilacor, Diltia (diltiazem)	$ 108 kwa 30, 240 mg makapisozi otulutsidwa	Pezani makuponi a Cardizem	Zambiri za Cardizem
DynaCirc (isradipine)	$ 100 kwa 60, 2.5 mg makapisozi	Pezani ma coupon a isradipine	Zambiri za Isradipine
Nimotop (nimodipine)	$ 578 for 30, 30 mg makapisozi	Pezani makuponi a nimodipine	Zambiri za Nimodipine
Norvasc (amlodipine)	$ 55 pa mapiritsi 30, 5 mg	Pezani makuponi amlodipine	Zambiri za Amlodipine
Plendil (felodipine)	$ 63 pa 30, 5 mg mapiritsi otulutsidwa	Pezani makuponi a felodipine	Zambiri za Felodipine
Procardia, Adalat CC (nifedipine)	$ 59 for 30, 30 mg mapiritsi otulutsidwa	Pezani makuponi a nifedipine	Zambiri za Nifedipine
Madzi (nisoldipine)	$ 184 ya 100, mapiritsi otulutsidwa a 8.5 mg	Pezani ma coupon a nisoldipine	Zambiri za Nisoldipine

Zina zotsekemera za calcium

Kuphatikiza pa zotsekera pakamwa za calcium, palinso ma jekeseni oletsa calcium. Izi zikuphatikizapo Cleviprex (clevidipine), komanso diltiazem, verapamil, ndi nicardipine.

Kodi calcium channel blockers ndi chiyani?

Ma calcium channel blockers (CCBs) amatchedwanso calcium antagonists. Amaletsa calcium kuti isalowe mumtima ndi m'mitsempha yamagazi, ndipo pochita izi, amathandizira minofu kumasuka. Ma CCB amatha kugwiritsidwa ntchito pochiza matenda osiyanasiyana, kuphatikiza kuthamanga kwa magazi, kuthamanga kwa mtima, komanso kupweteka pachifuwa. Ma CCB nthawi zambiri amapatsidwa ndi dokotala wazachipatala wamkati kapena wamankhwala a mtima (dokotala wamtima).

Kodi ma calcium block blocker amagwira ntchito bwanji?

Ma blockal calcium blockers amamanga njira za L-calcium ndipo amaletsa calcium kuti isalowe m'maselo osalala amtima ndi mitsempha. Calcium imayambitsa kutsutsana kwamphamvu komanso kwamphamvu. Chifukwa chake, pochepetsa calcium, mtima sumagwira mwamphamvu. Ma CCB amasangalala ndikufutukula mitsempha yamagazi, kugunda kwa mtima, komanso kuthamanga kwa magazi.

Kodi ma calcium block blocker amagwiritsidwa ntchito bwanji?

Ngakhale zisonyezero zimasiyanasiyana ndi malonda, ma CCB atha kugwiritsidwa ntchito payokha kapena kuphatikiza mankhwala ena-monga mafuta a cholesterol kapena mankhwala ena a magazi. Katswiri wamatenda atha kupatsa CCBs kuti:

Matenda oopsa (kuthamanga kwa magazi)
Kuphipha koronary
Angina pectoris (kupweteka pachifuwa) komwe kumalumikizidwa ndi matenda amitsempha yamtenda (matenda amtima kapena matenda amtima)
Arrhythmia (kugunda kwamtima kosazolowereka)
Supraventricular dysrhythmias (kugunda kwamphamvu mwachangu)
Hypertrophic cardiomyopathy (minofu yayikulu modabwitsa)
Kuthamanga kwa magazi m'mapapo (kuthamanga kwa magazi komwe kumakhudza mapapo)
Chodabwitsa cha Raynaud (kuchepa kwa magazi mpaka kumapeto, ndikupangitsa dzanzi)
Kutaya magazi kwa Subarachnoid (kutuluka magazi pakati paubongo ndi minofu yomwe imakhudza ubongo)
Migraine kupewa

Mitundu ya calcium channel blockers

Ma calcium block blocker amatha kusankhidwa ngati dihydropyridines ndi nondihydropyridines. Ma CCB amapezeka munjira zazifupi komanso zazitali.

Ma dihydropyridines

Ma CCBwa amamangiriza kuzitsulo za calcium mu minofu yosalala, yomwe imayambitsa kupuma kwa magazi komanso kutsika kwa magazi. Zitsanzo za dihydropyridines ndi amlodipine, nifedipine, ndi felodipine.

Nondihydropyridines

Ma CCBwa amamangiriza kuma calcium mu sinoatrial ndi atrioventricular node ndipo imakhudza minofu ya mtima ndi mitsempha yamagazi. Zitsanzo za nondihydropyridines zimaphatikizapo verapamil ndi diltiazem.

Ndani angatenge zotsekemera za calcium?

Amuna ndi akazi nthawi zambiri amatha kutenga ma CCB pokhapokha atagwera mgulu lazinthu zotsutsana zomwe zatchulidwa pansipa. Dokotala wanu amatha kuwunikiranso zamankhwala, mbiri, ndi mankhwala omwe mumamwa kuti muwonetsetse kuti CCB ndiyabwino kwa inu.

Amayi omwe ali ndi pakati, omwe akukonzekera kutenga pakati kapena kuyamwitsa ayenera kufunsa othandizira azaumoyo kuti akalandire upangiri waukadaulo wokhudzana ndi CCB.

Amlodipine itha kugwiritsidwa ntchito kwa ana azaka zisanu ndi chimodzi kapena kupitilira matenda a matenda oopsa. Nifedipine , alireza , ndi alireza , komano, sanaphunzitsidwe mwa ana.

Nthawi zambiri, achikulire amatha kutenga ma CCB. Komabe, chifukwa chakuchepa kwa ntchito ya impso, chiwindi, kapena mtima, komanso kuthekera kogwiritsa ntchito mankhwala osokoneza bongo (kutengera munthuyo), dosing iyenera kuyamba kumapeto kwenikweni, kukulira pang'onopang'ono ngati ikuloledwa ngati pakufunika kutero dokotala.

Kodi zotsekemera zama calcium ndizabwino?

Akukumbukira

Amlodipine wakhala anakumbukira ngati gawo limodzi la mankhwala (mankhwala omwe ali ndi amlodipine kuphatikiza mankhwala ena piritsi limodzi), koma osagwiritsa ntchito mankhwala amodzi.

Zoletsa

Ma CCB onse ali wotsutsa (sayenera kugwiritsidwa ntchito) mwa anthu omwe ali ndi:

Ziwengo kwa mankhwala kapena zosakaniza
Sick sinus syndrome (kupatula odwala omwe ali ndi pacemaker yokumba)
Kuthamanga kwambiri kwa magazi
Matenda a mtima wam'mimba (matenda amtima)
Kuchulukana m'mapapo

ZOKHUDZA: Kumangidwa kwamtima motsutsana ndi vuto la mtima: Kodi pali kusiyana?

Chifukwa cha kuthekera kochepetsa kugunda kwa mtima ndikuwonjezera mtima kutulutsa, nondihydropyridine CCBs imatsutsana mwa anthu omwe ali ndi:

Kulephera kwa mtima ndikuchepetsa kachigawo kakang'ono ka ejection (kumanzere kwamitsempha yamagetsi sikumapopa komanso koyenera)
Kutsekedwa kwachiwiri kapena kwachitatu kwa AV
Matenda odwala sinus

Machenjezo ena:

Ma CCB amatha kuyambitsa ma blockade a AV kapena sinus bradycardia, makamaka ngati atatengedwa ndi mankhwala ena omwe amatha kuchepa kwamtima.
Kuthamanga kwa magazi kapena osakomoka kumatha kuchitika.
Kutupa (edema) kwa mikono ndi miyendo kumatha kuchitika.
Gwiritsani ntchito mosamala mwa anthu omwe ali ndi vuto la chiwindi kapena impso.
Osatafuna kapena kuphwanya mafotokozedwe ataliatali-mayina amankhwalawa nthawi zambiri amatha mu CD, XR, XL, kapena XT ndipo amatanthauza kuti azituluka pakapita nthawi. Funsani wamankhwala wanu ngati simukudziwa ngati mankhwala anu atulutsidwa mwachangu kapena atulutsidwa.
Uzani dokotala wanu zamankhwala anu onse kuti athe kuwonetsetsa kuti CCB ndiyabwino kwa inu.
Ma CCB amatha kulumikizana ndi mankhwala ena. Uzani dokotala wanu za mankhwala onse omwe mumamwa, kuphatikizapo mankhwala akuchipatala, mankhwala owonjezera, ndi mavitamini.
Osasuta kapena kumwa mowa mukatenga CCB.
Madzi amphesa amalumikizana ndi ma CCB ena. Funsani wothandizira zaumoyo wanu ngati mungathe kudya zipatso za manyumwa ndi CCB yanu.

Kodi mungatenge zotsekemera zama calcium mukakhala ndi pakati kapena poyamwitsa?

Ma CCB ena atha kugwiritsidwa ntchito panthawi yapakati, monga zimatsimikizidwira pazochitika ndi kuyang'aniridwa ndi dokotala. Chifukwa pali zambiri pazama CCB komanso kutenga pakati, nthawi zambiri, ma CCB amangogwiritsidwa ntchito panthawi yapakati ngati akufunikira komanso ngati maubwino apitilira zoopsa zake.

Kugwiritsa ntchito CCB mukamayamwitsa kungakhale kotetezeka koma fufuzani ndi dokotala kuti muwonetsetse kuti ndikotetezeka kwa inu kutengera matenda anu komanso mbiri yanu.

Funsani dokotala musanagwiritse ntchito CCB ngati muli ndi pakati, mukukonzekera kutenga pakati, kapena mukuyamwitsa.

Kodi calcium channel blockers imayang'aniridwa ndi zinthu?

Ayi, zotsekemera zama calcium sizinthu zoyendetsedwa.

Zotsatira zoyipa za calcium channel blocker

Zotsatira zoyipa za calcium channel blockers ndi awa:

Kutopa
Kuthamanga
Kutupa kwa mimba, akakolo, mapazi
Kutentha pa chifuwa, kupweteka m'mimba, nseru
Arrhythmia (kugunda kwamtima) kapena kugwedeza (kugunda kwamtima)
Kudzimbidwa
Chizungulire

Zotsatira zina zomwe sizodziwika bwino zimaphatikizapo kuthamanga (tachycardia) kapena kuchepa kwa mtima (bradycardia) kugunda kwa mtima, kupumira, kukhosomola, kupuma movutikira, kuvutika kumeza, komanso kufooka kapena kumva kulira m'manja kapena m'mapazi.

Zotsatira zoyipa zomwe zimapezeka kawirikawiri zimaphatikizapo kupweteka mutu, kukomoka, jaundice, malungo, zotupa, maloto owoneka bwino, ndi matama otupa.

Nthawi zambiri, kudwala kwamtima kumatha kuchitika kapena kupweteka pachifuwa kumatha kukulira poyambitsa CCB. Izi zikachitika, pitani kuchipatala mwadzidzidzi.

Zomwe zimayambitsa matendawa zimakhala zochepa. Ngati muli ndi zizindikiro zosafunikira, monga ming'oma, kupuma movutikira, kapena kutupa kwa nkhope, milomo, kapena lilime, pitani kuchipatala mwadzidzidzi.

Zotsatira zina zimatha kuchitika. Funsani akatswiri azachipatala anu kuti muwone mndandanda wazovuta zomwe zimakhudzana ndi ma CCB.

Kodi ma calcium block blocker amawononga ndalama zingati?

Mtengo wa calcium channel blockers umasiyanasiyana ndi mankhwala, mlingo, ndi kuchuluka. Ma CCB amachokera pa $ 55 mpaka $ 950 popanda inshuwaransi komanso kuchotsera kusanachitike. Komabe, ma CCB ambiri amapezeka pamitundu yotsika mtengo yomwe imawononga ndalama zosakwana $ 10 pamwezi ndi inshuwaransi kapena ndi khadi yotsatsira. M'malo mwake, kugwiritsa ntchito coupon yaulere ya SingleCare ikhoza kukupulumutsirani mpaka 80% pamankhwala anu. Funsani wamankhwala wanu kuti akuthandizeni kufananiza mitengo pamankhwala anu.