Xiidra vs. Restasis: Kusiyana, kufanana, ndi zomwe zili zabwino kwa inu
Mankhwala osokoneza bongo Vs. MnzanuKuwunika kwa mankhwala osokoneza bongo & kusiyana kwakukulu | Zinthu zothandizira | Mphamvu | Kuphunzira inshuwaransi ndikufanizira mtengo | Zotsatira zoyipa | Kuyanjana kwa mankhwala | Machenjezo | FAQ
Xiidra (lifitegrast) ndi Restasis (cyclosporine) ndi mankhwala omwe amagwiritsidwa ntchito pochiza matenda owuma m'maso. Anthu omwe ali ndi matenda owuma amaso amakhala opanda chinyezi m'maso ndipo sangathe kutulutsa misozi yokwanira kupaka m'maso. Vutoli limatha kubweretsa vuto m'maso ndi zovuta kuwerenga kapena kugwira ntchito pakompyuta, pakati pamavuto ena. Xiidra ndi Restasis ndi mankhwala oponya m'maso omwe amagwiritsidwa ntchito m'maso onse tsiku ndi tsiku.
Kodi pali kusiyana kotani pakati pa Xiidra ndi Restasis?
Xiidra
Xiidra, yomwe imadziwikanso ndi dzina loti genitegrast, imapangidwa ndi Shire. Anavomerezedwa ndi FDA mu 2016 mgulu latsopano la mankhwala lotchedwa lymphocyte function-associated antigen 1 (LFA-1) antagonists. Njira yeniyeni yomwe imagwirira ntchito sikudziwika. Komabe, amakhulupirira kuti amachepetsa kutupa ndikuwonjezeka kupanga misozi poletsa puloteni yotchedwa LFA-1 kuti isalumikizane ndi puloteni ina yotchedwa ICAM-1 m'maso.
Xiidra ndi yankho la 5% lamutu wamutu lomwe limaperekedwa ngati dontho limodzi m'diso lililonse kawiri patsiku (pafupifupi maola 12 kupatukana). Itha kuthandiza kuthetsa kuuma kwa diso mkati mwa milungu iwiri, ngakhale zimatha kutenga milungu isanu ndi umodzi mpaka 12 kuti ipereke mpumulo wathunthu kwa anthu ena.
Kubwezeretsa
Restasis idavomerezedwa ndi FDA mu 1983 kuti ichepetse kuwuma m'maso. Amapangidwa ndi Allergan ndipo amadziwika ndi dzina lodziwika bwino, cyclosporine. Restasis amakhulupirira kuti imagwira ntchito poyang'anira zotupa m'maso zomwe zingakhudze kupangika kwa misozi.
Restasis ndi 0.05% ya emulsion yamaso yomwe imayikidwa m'maso kawiri tsiku lililonse kapena maola 12 aliwonse. Zitha kutenga miyezi itatu kuti mupumule ndi Restasis. Kwa anthu ena, zimatha mpaka miyezi isanu ndi umodzi kuti athandizidwe mokwanira.
| Kusiyana kwakukulu pakati pa Xiidra ndi Restasis | ||
|---|---|---|
| Xiidra | Kubwezeretsa | |
| Gulu la mankhwala osokoneza bongo | Wotsutsa wa Lymphocyte wothandizira antigen 1 (LFA-1) | Calcineurin inhibitor immunosuppressant |
| Chizindikiro cha Brand / generic | Palibe mtundu wa generic womwe ulipo | Palibe mtundu wa generic womwe ulipo |
| Kodi dzina lachibadwa ndi liti? | Chombo | Cyclosporine |
| Kodi mankhwalawa amabwera mwa mawonekedwe ati? | Yankho la ophthalmic | Emulsion ya ophthalmic |
| Kodi mulingo woyenera ndi uti? | Dontho limodzi m'diso lililonse kawiri tsiku lililonse kapena maola 12 aliwonse | Dontho limodzi m'diso lililonse kawiri tsiku lililonse kapena maola 12 aliwonse |
| Kodi mankhwalawa amatenga nthawi yayitali bwanji? | Mankhwalawa amagwiritsidwa ntchito ngati chithandizo chanthawi yayitali | Mankhwalawa amagwiritsidwa ntchito ngati chithandizo chanthawi yayitali |
| Ndani amagwiritsa ntchito mankhwalawa? | Akuluakulu ndi achinyamata azaka 17 kapena kupitilira apo | Akuluakulu ndi achinyamata azaka 16 kapena kupitilira apo |
Zomwe zimathandizidwa ndi Xiidra ndi Restasis
Xiidra ndi Restasis onse amavomerezedwa kuti athetse matenda amaso owuma, omwe amadziwika kuti matenda owuma a diso . Matenda owuma amaso amatha kuphatikizidwa ndi zinthu zina zamaso monga blepharitis, kapena kutupa kwa zikope, zomwe zimayambitsidwa ndi chifuwa kapena mavuto ena. Mankhwalawa amathandizira kukulitsa kutulutsa kwa misozi ndikuchepetsa kutupa pamaso.
Kuphatikiza pakuuma, Xiidra ndi Restasis zitha kuthandizira kuthana ndi matenda ena amaso owuma, kuphatikiza kufiira m'maso, kutopa m'maso, kusawona bwino, komanso kuyabwa m'maso. Madokotala ena amalimbikitsa chithandizo chowonjezera mukamagwiritsa ntchito Xiidra kapena Restasis, monga ma compress ofunda kuti atonthoze diso.
| Mkhalidwe | Xiidra | Kubwezeretsa |
| Matenda owuma a diso | Inde | Inde |
Kodi Xiidra kapena Restasis ndiyothandiza kwambiri?
Pakadali pano palibe mayesero azachipatala omwe amafanizira mwachindunji mphamvu ya Xiidra motsutsana ndi Restasis ya matenda owuma m'maso. Komabe, mankhwala onsewa awonetsedwa kuti ndi othandiza m'mayeso azachipatala poyerekeza ndi placebo. Mankhwala othandiza kwambiri ndi omwe amakuthandizani kwambiri.
M'mayeso anayi azachipatala, osiyanasiyana mphamvu ndi chitetezo cha lifitegrast adayesedwa mwa odwala 1,181. Pakutha kwa masabata a 12, panali kusintha kwakukulu kwa omwe amagwiritsa ntchito lifitegrast ya matenda owuma m'maso. Score Dryness Score idagwiritsidwa ntchito kuwunika kusapeza bwino pakumwa.
Cyclosporine, chinthu chogwira ntchito ku Restasis, anali adaphunzira mayesero anayi osinthidwa Omwe ali ndi odwala pafupifupi 1,200 omwe ali ndi zizindikilo zowopsa zamaso. Pambuyo pa miyezi isanu ndi umodzi, panali misozi yowonjezeka kwambiri mwa 15% ya odwala omwe amathandizidwa ndi cyclosporine motsutsana ndi 5% ya odwala omwe amathandizidwa ndi placebo.
Funsani wothandizira zaumoyo kuti adziwe njira yabwino kwambiri yothandizira. Mutha kutumizidwa kwa katswiri wazamankhwala kapena dotolo yemwe amadziwika ndi ophthalmology ya matenda anu.
Kuphunzira ndi kuyerekezera mtengo kwa Xiidra vs. Restasis
Xiidra sikuti nthawi zambiri imakhala ndi mapulani a inshuwaransi ya Medicare. Palibe njira ina ya Xiidra, chifukwa nthawi zambiri imakhala yotsika mtengo. Ndalama za Copay zimatha kusiyanasiyana kutengera dongosolo la inshuwaransi. Popanda inshuwaransi, khadi ya coupon ya SingleCare Xiidra ikhoza kuthandizira kutsitsa mtengo wamankhwala pafupifupi $ 580. Kupanda kutero, mtengo wotsika wa Xiidra uli pafupifupi $ 730.
Restasis imangopezeka ngati mankhwala odziwika ndi dzina. Komabe, njira zambiri za Medicare ndi inshuwaransi zimakhudza Restasis. Ma Copays amatha kusiyanasiyana kutengera dongosolo la inshuwaransi. Popanda inshuwaransi, mtengo wapakati wa Restasis ndi pafupifupi $ 389. Kugwiritsa ntchito coupon kumathandizira kutsitsa mtengo wa Restasis. Coupon ya SingleCare Restasis ikupezeka kuti igwiritsidwe ntchito kuma pharmacies omwe akutenga nawo mbali ndipo ichepetsa mtengo wa Restasis mpaka $ 255.
| Xiidra | Kubwezeretsa | |
| Nthawi zambiri amakhala ndi inshuwaransi? | Ayi | Inde |
| Nthawi zambiri amakhala ndi Medicare Part D? | Ayi | Inde |
| Kuchuluka | Makontena 60 ogwiritsira ntchito kamodzi | 60 Mbale |
| Wopanga Medicare wamba | $ 3 mpaka $ 637 | $ 19 mpaka $ 652 |
| Mtengo wosakwatiwa | $ 578 + | $ 255 + |
Zotsatira zoyipa za Xiidra vs. Restasis
Zotsatira zoyipa kwambiri za Xiidra ndimakwiya komanso kufiira m'maso, kutulutsa kwamaso, kupweteka mutu, komanso kusawona bwino. Xiidra amathanso kuyambitsa kukoma kosazolowereka pakamwa, kotchedwanso dysgeusia.
Zotsatira zoyipa kwambiri za Restasis zimaphatikizapo kuyaka, kupsa mtima, ndi kufiyira m'maso, komanso kusawona bwino. Restasis sichidziwika kuti imayambitsa malingaliro osokonekera; komabe, zitha kukhala zotheka kuposa Xiidra kuyambitsa moto woyaka m'maso mutatha kuyang'anira.
Zotsatira zoyipa za Xiidra ndi Restasis zimakhudzanso kutengeka kwa hypersensitivity. Zizindikiro za hypersensitivity reaction zimaphatikizapo kuthamanga, kutupa, kuyabwa, ndi kupuma movutikira.
| Xiidra | Kubwezeretsa | |||
| Zotsatira zoyipa | Zoyenera? | Pafupipafupi | Zoyenera? | Pafupipafupi |
| Kupsa mtima kwa diso | Inde | 5% –25% | Inde | 1% –5% |
| Kutentha kwamaso | Inde | 1% –5% | Inde | 17% |
| Kufiira kwa maso | Inde | 1% –5% | Inde | 1% –5% |
| Masomphenya olakwika | Inde | 5% –25% | Inde | 1% –5% |
| Kukoma kosazolowereka | Inde | 5% –25% | Ayi | - |
| Kutulutsa maso | Inde | 1% –5% | Inde | 1% –5% |
| Kupweteka kwa diso kapena kupweteka | Inde | 1% –5% | Inde | 1% –5% |
| Mutu | Inde | 1% –5% | Ayi | - |
Pafupipafupi sizidalira zomwe zimayesedwa pamutu. Izi sizingakhale mndandanda wathunthu wazovuta zomwe zingachitike. Chonde onani dokotala wanu kapena wothandizira zaumoyo kuti mudziwe zambiri.
Gwero: DailyMed ( Xiidra ), Tsiku Lililonse ( Kubwezeretsa )
Kuyanjana kwa mankhwala a Xiidra vs. Restasis
Palibe kuyanjana kwakukulu kwa mankhwala komwe kunanenedwa ndi Xiidra kapena Restasis. Mankhwala ena oponya m'maso ayenera kupewedwa pogwiritsa ntchito Xiidra kapena Restasis pokhapokha atalangizidwa ndi othandizira azaumoyo. Uzani dokotala wanu za mankhwala omwe mungamwe, monga mankhwala akuchipatala, mavitamini, ndi mankhwala azitsamba.
Machenjezo a Xiidra ndi Restasis
Kukhudza nsonga ya chidebecho, botolo, kapena botolo molunjika kumaso kapena malo oyandikana nawo ziyenera kupewedwa panthawi yoyang'anira. Kuchita izi kumatha kuonjezera chiopsezo cha kuipitsidwa, komwe kumatha kubweretsa matenda m'maso . Kukhudza nsonga ya chidebecho, botolo, kapena botolo m'maso kumathanso kuvulaza.
Magalasi olumikizana akuyenera kuchotsedwa asadaperekedwe Xiidra kapena Restasis. Magalasi olumikizirana amatha kuyikanso mphindi 15 mutagwiritsa ntchito Xiidra kapena Restasis.
Zida zogwiritsa ntchito kamodzi za Xiidra ziyenera kugwiritsidwa ntchito atangotsegula. Ayenera kutayidwa atapereka mankhwala.
Funsani wothandizira zaumoyo kuti akuchenjezeni ndi zodzitetezera zokhudzana ndi Xiidra kapena Restasis.
Mafunso omwe amafunsidwa kawirikawiri za Xiidra vs. Restasis
Xiidra ndi chiyani?
Xiidra ndi dzina lotchedwa ophthalmic solution yomwe imagwiritsidwa ntchito pochiza matenda amaso owuma. Amadziwika kuti ndi wotsutsana ndi LFA-1 yemwe amaletsa kulumikizana kwa mapuloteni ena kuti achepetse kutupa. Dzinalo la Xiidra ndilopatsa moyo; komabe, palibe mitundu ina ya Xiidra yomwe ikupezeka pano. Xiidra imayendetsedwa kawiri tsiku lililonse kuti muchepetse kuuma m'maso. Amapangidwa ndi Shire.
Restasis ndi chiyani?
Restasis ndi dzina la cyclosporine ophthalmic solution, lomwe limapangidwa ndi Allergan. Amapatsidwa kawiri tsiku lililonse kuti athetse matenda owuma m'maso. Imagwira ngati calcineurin inhibitor immunosuppressant Kuchepetsa kutupa ndikuwonjezera kutulutsa misozi m'maso. Palibe mitundu ina ya Restasis yomwe ikupezeka pano.
Kodi Xiidra ndi Restasis ndizofanana?
Onse Xiidra ndi Restasis ali ndi zotsutsana ndi zotupa, koma sizofanana. Xiidra ndi wotsutsana ndi LFA-1 pomwe Restasis ndi calcineurin inhibitor. Amapangidwa ndimakampani opanga mankhwala osiyanasiyana ndipo amabwera mosiyanasiyana. Xiidra ndi yankho la maso lomwe limabwera muzitsulo zogwiritsa ntchito kamodzi. Restasis ndi emulsion ya ophthalmic yomwe imabwera mumitsuko yogwiritsira ntchito kamodzi kapena botolo lopanda mankhwala ambiri.
Kodi Xiidra kapena Restasis ndibwino?
Xiidra ndi Restasis zonse ndizothandiza kuchiza matenda owuma amaso. Komabe, Xiidra imatha kuthana ndi vuto la maso owuma mwachangu kuposa Restasis. Xiidra imatha kuyamba kugwira ntchito mkati mwa milungu iwiri pomwe Restasis nthawi zambiri imatenga miyezi itatu kuti iyambe kuyanika pamaso.
Kodi nditha kugwiritsa ntchito Xiidra kapena Restasis ndili ndi pakati?
Kugwiritsa ntchito Xiidra kapena Restasis pomwe mayi ali ndi pakati nthawi zambiri amakhala otetezeka. Popeza Xiidra ndi Restasis amaperekedwa m'maso, samalowa m'magazi ambiri. Chifukwa chake, chiopsezo cha zolephereka kubadwa mukamagwiritsa ntchito Xiidra kapena Restasis ndi chochepa. Funsani wothandizira zaumoyo ngati muli ndi pakati kapena mukuyamwitsa.
Kodi ndingagwiritse ntchito Xiidra kapena Restasis ndi mowa?
Xiidra ndi Restasis sizimalowetsedwa m'magazi ambiri. M'malo mwake, mankhwalawa amagwira ntchito m'maso. Xiidra ndi Restasis sadziwika kuti amalumikizana ndi mowa.
Kodi Xiidra ingachiritse maso owuma?
Xiidra imagwiritsidwa ntchito pochiza maso owuma omwe amaphatikizidwa ndi matenda amaso owuma kapena blepharitis. Amagwiritsidwa ntchito ngati chithandizo chanthawi yayitali kuti athetse maso owuma. Ngati Xiidra yasiya, kuwuma m'maso kumatha kubwerera.
Kodi Xiidra ndi steroid?
Xiidra si steroid. Lili ndi chinthu chogwiritsira ntchito chopatsa moyo, chomwe chimagwira ngati wotsutsana ndi lymphocyte anti-1 (LFA-1). Zimagwira poletsa puloteni yotchedwa LFA-1 kuti isalumikizane ndi puloteni yotchedwa ICAM-1. Kuyanjana kwa mapuloteniwa kumathandizira pakatupa m'maso.
Kodi Xiidra imachepetsa kutupa?
Xiidra ndi mankhwala othandiza omwe amathandiza kuchepetsa kutupa ndi kuuma m'maso. Itha kuyamba kutsitsimula maso owuma pasanathe milungu iwiri, ngakhale imatha kutenga milungu 12 kuti ipereke mpumulo wathunthu. Xiidra imayendetsedwa kawiri tsiku lililonse ngati yankho la ophthalmic.
Kodi pali njira yotsika mtengo m'malo mwa Restasis?
Pakhoza kukhala njira yotsika mtengo yotsika ku Restasis yomwe ikupanga koma mwina singapezekebe. Wopereka chithandizo chamankhwala angakulimbikitseni mankhwala ena ogulitsira ngati misozi yokumba kuyanika kwakanthawi kapena kukwiya m'maso. Restasis ndi mankhwala omwe adalangizidwa kuti azitha kuchiritsa matenda amaso owuma.
