Kutenga Trintellix chifukwa cha nkhawa? Nazi zomwe muyenera kudziwa

Zambiri Zamankhwala

Trintellix ndi mankhwala opatsirana pogonana omwe FDA imavomereza kuti athetse vuto lalikulu lachisokonezo (MDD). Zimagwira ntchito moyerekeza magawo a neurotransmitter serotonin, yomwe imagwira ntchito yofunikira pamamvedwe, malingaliro, ndi njala. Chifukwa chakuti serotonin imakhulupirira kuti imathandizira kuthana ndi nkhawa, Trintellix nthawi zina amagwiritsidwanso ntchito pochotsa nkhawa. Tiyeni tiwone mozama za kutenga Trintellix chifukwa cha nkhawa.

Kodi Trintellix imagwirira ntchito nkhawa?

Trintellix ndi amodzi mwamankhwala omwe amatchedwa vortioxetine, omwe ali mgulu la mankhwala omwe amatchedwa serotonin reuptake inhibitors (SSRIs). Zamgululi kale ankatchedwa Brintellix, koma adasinthidwa dzina mu 2016 chifukwa nthawi zambiri ankasokonezeka ndi mankhwala a antiplatelet otchedwa Brilinta. Kutchulanso mankhwalawa ku Trintellix kwathandiza kuchepetsa chisokonezo kwa madokotala ndi odwala.

Trintellix ndi SSRI yomwe ingathandize kukonza momwe munthu akumvera, momwe akumvera, komanso momwe amagonera. Food and Drug Administration (FDA) yavomereza kokha Trintellix kuti athetse vuto lalikulu lachisoni, koma atha kulembedwa osalemba kuthana ndi nkhawa.

Kulemba pamakalata kumachitika pomwe dokotala amapatsa wodwala mankhwala omwe FDA imavomereza kuti athetse vuto lomwe ndi losiyana ndi lomwe wodwalayo ali nalo. Izi ndizochitika kawirikawiri zomwe ndizovomerezeka kwathunthu, ndipo zikuyerekeza kuti pafupifupi 1 mwa mankhwala asanu alidi ovomerezeka.

Chifukwa chake dokotala amatha kulembera wina ali ndi nkhawa mankhwala a Trintellix, koma bwanji angachite izi ngakhale pali mankhwala ena ambiri othana ndi nkhawa pamsika? Trintellix imatseka kubwezeretsanso kwa serotonin monga ma SSRIs ena, koma mosiyana ndi ma anti-depressant ena, imakhalanso ndi zovuta zotsutsana ndi 5-HT1A ndi 5-HT3 serotonin receptors muubongo. Ochita kafukufuku sakudziwa momwe izi zimagwirira ntchito, koma amakhulupirira kuti zimathandizira zotsatira zopondereza za Trintellix .

Maphunziro awonetsa kuti Trintellix imathandizira kusintha kwa matenda amisala wamba kuposa placebo komanso kuti ndi othandiza komanso olekerera kwa odwala omwe ali ndi nkhawa yayikulu. Kafukufuku wosanthula meta wofalitsidwa mu Zolinga Zamakono Zamankhwala magaziniyi inapeza kuti Trintellix ndi yothandiza kwa anthu omwe ali ndi matenda ovutika maganizo omwe ali ndi zotsatira zochepa chabe. Ponseponse, zatsimikizira kukhala zothandiza pochepetsa nkhawa komanso kukhumudwa kwa anthu omwe ali ndi vuto lalikulu lokhumudwa kapena kuda nkhawa kwambiri.

Kuyambira Trintellix chifukwa cha nkhawa

Kuyambitsa mankhwala atsopano kungakhale kovuta, ndipo ngati muli ndi nkhawa kale, kudziwa zomwe muyenera kuyembekezera mukayamba kumwa Trintellix kungathandize kuti ntchitoyi ikhale yosavuta. Chimodzi mwazinthu zofunika kuzidziwa mukamayamba kumwa Trintellix ndikuti si mankhwala othamanga. Zitha kutenga nthawi kuti muyambe kuwona kuti nkhawa zanu zikuyenda bwino. Zitha kutenga masabata awiri kapena anayi (kapena kupitilira apo) kuti mumve zonse za Trintellix.

Mlingo

Trintellix imapezeka ngati piritsi lotulutsira mwachangu mu mphamvu zitatu: 5 mg, 10 mg, ndi 20 mg. Mlingo woyambira wa Trintellix ndi 10 mg amatengedwa kamodzi patsiku kapena wopanda chakudya. Mlingowu ukhoza kuwonjezeka mpaka 20 mg patsiku kapena kutsika mpaka 5 mg patsiku kutengera momwe mankhwalawa amagwirira ntchito kapena zovuta zina zomwe zimakumana nazo.

Kuchuluka kwenikweni kwa Trintellix komwe muyenera kutenga ndi nthawi yayitali bwanji kuti mutenge kudzasiyana malinga ndi zizindikiritso zanu komanso mbiri yazachipatala. Kutenga mlingo waukulu kapena mlingo woposa umodzi wa Trintellix poyesera kuti uzigwira ntchito mofulumira sikuli kotetezeka ndipo kungayambitse mavuto. Ichi ndichifukwa chake ndikofunikira kukambirana ndi omwe amakuthandizani pa zaumoyo wanu za mlingo woyenera wothandizira nkhawa zanu. Ngati mwatenga Trintellix wambiri muyenera kuyimbira dokotala kapena Poison Control Center ku 1-800-222-1222. Atha kukulangizani ngati muyenera kupita kuchipinda chadzidzidzi kapena kuchipatala.

Kuyanjana

Trintellix sayenera kumwa nthawi imodzimodzi ndi mankhwala enaake chifukwa chothandizidwa ndi mankhwala osokoneza bongo. Sitiyenera kumwedwa pasanathe milungu iwiri mutatenga:

• Monoamine Oxidase Inhibitors (MAOIs)
• Methylene buluu
• Mzere

Trintellix sayenera kutengedwa mkati mwa milungu iwiri mutatenga monoamine oxidase inhibitor (MAOI), ndipo MAOI sayenera kutengedwa mkati mwa masiku 21 atayimitsa Trintellix chifukwa cha chiopsezo chokumana ndi matenda a serotonin. Matenda a Serotonin ndiwopseza moyo womwe umachitika serotonin ikamakula mthupi. Zizindikiro za matenda a serotonin zimaphatikizapo kunjenjemera, kunjenjemera, kuthamanga kwa magazi, kugunda kwamtima mwachangu, kusokonezeka, kulimba kwa minofu, ndi kugwidwa.

Muyenera kuuza dokotala ngati mukumwetsanso mankhwala aliwonsewa, chifukwa angakhudze momwe Trintellix imagwirira ntchito kapena kuwonjezera chiopsezo cha zotsatirapo zake:

• Zovuta zina
• Mankhwala oletsa antipsychotic
• Mankhwala opweteka kwambiri monga NSAID kapena aspirin
• Ochepetsa magazi ngati Coumadin (warfarin)
• Mankhwala a Triptan kapena tryptophan othandizira
• Okodzetsa
• St. John's Wort
• Carbamazepine
• Fentanyl
• Lifiyamu
• Phenytoin
• Quinidine
• Bupropion
• Buspirone
• Rifampin
• Zamgululi

Zotsatira zoyipa

Mukayamba kumwa Trintellix, mutha kukhala ndi zovuta zina. Anthu ena amatha kukhala opanda nkhawa kapena olimbikitsidwa atangomwa mankhwala, zomwe zingayambitse kugona. Nazi zotsatira zina zoyipa zomwe anthu amakumana nazo akayamba kumwa Trintellix:

• Nseru
• Kusanza
• Kudzimbidwa
• Kutsekula m'mimba
• Pakamwa pouma
• Kuuma kwa minofu
• Gasi
• Kulemera
• Maloto achilendo
• Kupweteka kwa diso
• Masomphenya akusintha
• Chizungulire
• Kulephera kugonana

Ndikofunika kuti musapewe kumwa Trintellix kuti muwonetsetse kuti mankhwalawa akukhalabe osasintha ndikuchepetsa chiopsezo chobwereranso kuzizindikiro zakukhumudwa. Ngati mwaphonya mlingo ndibwino kuti mutenge mlingo wanu wotsatira mukangokumbukira, pokhapokha ngati ili nthawi yoti mutenge mlingo wanu wotsatira. Kudziwiratu pamlingo kumatha kuyambitsa zovuta ndipo, nthawi zambiri, kumatha kuyambitsa matenda a serotonin. Ambiri opereka chithandizo chamankhwala amalimbikitsa kuti atenge Trintellix nthawi yofananira tsiku lililonse.

Ngakhale ndizosowa, Trintellix imatha kuyambitsa zovuta zina zomwe zimafunikira chithandizo chamankhwala. Chizindikiro cha FDA cha Trintellix chili ndi chenjezo la bokosi za malingaliro ofuna kudzipha komanso machitidwe, makamaka kwa ana, achinyamata, komanso achikulire. Ngati mutenga Trintellix ndikuyamba kukhala ndi malingaliro ofuna kudzipha kapena machitidwe, muyenera kupeza chithandizo chamankhwala nthawi yomweyo.

Trintellix amathanso kuyambitsa zovuta zina monga:

• Kutuluka magazi mosazolowereka
• Kuvulala kwachilendo
• Mania kapena hypomania mwa anthu omwe ali ndi vuto losinthasintha zochitika
• Kutseka kwa angilla glaucoma
• Magulu otsika a sodium m'magazi (hyponatremia)

Ngati mukumane ndi zovuta izi mukamamwa Trintellix muyenera kuyankhulana ndi omwe amakuthandizani posachedwa. Ngati muli ndi vuto la vortioxetine kapena zina zilizonse mu Trintellix muyenera kupewa kumwa mankhwalawa chifukwa amatha kuyambitsa mavuto ena.

Zoletsa

Anthu omwe ali ndi matenda ochititsa munthu kusinthasintha zochitika amatha kumwa Trintellix pokhapokha ngati angavomerezedwe ndi dokotala chifukwa amatha kuyambitsa magawo amanjenje. Anthu omwe ali ndi matenda a glaucoma ndi magazi akuyenera kungotenga Trintellix moyang'aniridwa ndi dokotala chifukwa zitha kuwonjezera chiopsezo chotuluka m'magazi ndikuwonjezera glaucoma yotsekedwa.

Mankhwala ena ndi osatetezeka kwa okalamba, koma a Trintellix awonetsedwa kuti ndi ololera komanso otetezeka kwa achikulire opitilira zaka 65. Maphunziro azachipatala sanawonetse kusiyana pakati pachitetezo kapena magwiridwe antchito pakati pa okalamba ndi achikulire, ndipo sipanakhalepo kusiyana kulikonse poyankha mankhwalawa pakati pa achikulire kapena achikulire mwina. Trintellix sivomerezeka kwa odwala aliwonse osakwana zaka 18.

Trintellix imakhudza mwana wosabadwayo mwa amayi apakati. Kutenga Trintellix mu trimester yachitatu ya mimba kumatha kubweretsa chiopsezo chowonjezeka a matenda omwe amatchedwa kuthamanga kwa magazi m'mimba mwa ana obadwa kumene. Palibe chidziwitso pa Trintellix ndi momwe zimakhudzira mkaka wa m'mawere kapena makanda oyamwitsa, ndichifukwa chake ndikofunikira kuyeza maubwino ndi zoopsa zogwiritsa ntchito mankhwalawa mukamayamwitsa ndi wothandizira zaumoyo.

Kodi njira yothanirana ndi nkhawa kwambiri ndi iti?

Palibe mankhwala amodzi omwe ndi othandiza kwambiri pochiza nkhawa. Zomwe zimagwirira ntchito munthu m'modzi sizingagwire ntchito kwa wina, koma nkhani yabwino ndiyakuti pali mitundu yambiri ya mankhwala opatsirana omwe amatha kuthana ndi nkhawa monga nkhawa. Kuphatikiza pa SSRIs, nayi magulu ena a antidepressants:

• Serotonin ndi norepinephrine reuptake inhibitors (SNRIs): kuonjezera kupezeka kwa serotonin ndi norepinephrine muubongo.
• Tricyclic antidepressants: kuonjezera kuchuluka kwa serotonin ndi norepinephrine muubongo ndikuletsa acetylcholine.
• Monoamine oxidase inhibitors (MAOIs): pewani michere ya monoamine oxidase kuti isachotse dopamine, serotonin, ndi norepinephrine kuubongo.

Nawa ena mwa mankhwala othandiza kuthana ndi nkhawa.

Kupsinjika maganizo kwa nkhawa
Dzina la mankhwala osokoneza bongo	Gulu la mankhwala osokoneza bongo	Kuchita bwino kwa nkhawa	Mlingo woyenera	Zotsatira zoyipa	Kusungidwa kwa SingleCare	Dziwani zambiri
Zamgululi	SSRI	Zatsimikiziridwa kukhala zothandiza kuposa ma placebo omwe amalamulidwa ndi placebo	5 mpaka 20 mg pa tsiku	Nseru, kudzimbidwa	Pezani ma coupon a Trintellix	Zambiri za Trintellix
Zoloft (nsabwe)	SSRI	Chothandiza kwambiri kuposa placebo pochiza matenda amisala ndi mantha	25 mpaka 200 mg patsiku	Nsautso, kutsegula m'mimba, ndi kuchepa kwa njala	Pezani ma coupon a Zoloft	Zambiri za Zoloft
Paxil (paroxetine)	SSRI	Kugwiritsa ntchito bwino pochiza matenda amisala komanso nkhawa zina	10 mpaka 60 mg patsiku	Kugona, nseru, ndi mutu	Pezani makuponi a Paxil	Zambiri za Paxil
Prozac (fluoxetine)	SSRI	Amagwiritsidwa ntchito kwambiri ngati chithandizo chothandizira matenda amantha	10 mpaka 60 mg patsiku	Kusowa tulo, nseru, ndi pakamwa pouma	Pezani ma coupons a Prozac	Zambiri za Prozac
Kameme (dzina loyamba)	SSRI	Zatsimikiziridwa kukhala zothandiza komanso zolekerera pochiza matenda amisala	10 mpaka 20 mg pa tsiku	Kusowa tulo, nseru, ndi kuchepa kwa libido	Pezani ma Lexapro coupons	Zambiri za Lexapro
Cymbalta (duloxetine)	SNRI	Amavomerezedwa kuti athetse vuto la nkhawa	30 mpaka 60 mg patsiku	Nsawawa, pakamwa pouma, ndi kusinza	Pezani ma coupon a Cymbalta	Zambiri za Cymbalta
Celexa(citalopram)	SSRI	Amagwiritsidwa ntchito pochiza kukhumudwa koma atha kugwiritsidwa ntchito ngati chizindikiro kuti athetse nkhawa	20 mpaka 40 mg pa tsiku	Nsawawa, pakamwa pouma, ndi mutu	Pezani ma Couponi a Celexa	Zambiri za Celexa
KuchitaXR(Kapisozi) (venlafaxine XR)	SNRI	Ovomerezeka pakuthana ndi matenda amisala, nkhawa zamagulu, komanso mantha	37.5 mpaka 225 mg patsiku	Nsautso, kusokonezeka, ndi pakamwa pouma	Pezani makuponi a Effexor XR	Zambiri za Effexor XR
Tofranil(imipramine)	Tricyclic antidepressant	Itha kugwiritsidwa ntchito ngati chizindikiro pochiza matenda amantha	100 mpaka 200 mg pa tsiku	Pakamwa pouma, chizungulire, ndi kugona	Pezani ma coupon a Tofranil	Zambiri za Tofranil