Tresiba vs. Toujeo: Kusiyana, kufanana, ndi zomwe zili zabwino kwa inu
Mankhwala osokoneza bongo Vs. MnzanuKuwunika kwa mankhwala osokoneza bongo & kusiyana kwakukulu | Zinthu zothandizira | Mphamvu | Kuphunzira inshuwaransi ndikufanizira mtengo | Zotsatira zoyipa | Kuyanjana kwa mankhwala | Machenjezo | FAQ
Tresiba ndi Toujeo ndi ma insulini awiri osiyana omwe amagwiritsidwa ntchito kuthana ndi shuga m'magazi mwa iwo omwe ali ndi matenda ashuga. Tresiba ndi insulin yotenga nthawi yayitali ndipo Toujeo ndi insulin yotenga nthawi yayitali. Mwina insulini itha kuperekedwa kwa akulu kapena ana kuti athe kuchepetsa shuga tsiku lonse.
Poyerekeza ndi insulins yochita kwakanthawi, Tresiba (insulin degludec) ndi Toujeo (insulin glargine) adapangidwa kuti atulutse insulini kwakanthawi. Chifukwa cha kutalika kwa nthawi yayitali, ma insuliniwa amatha kuthandiza kupereka shuga wokhazikika m'magazi ndikuchepetsa chiopsezo cha hypoglycemia (shuga wotsika kwambiri magazi). Ngakhale kufanana ndi momwe amagwiritsidwira ntchito, Tresiba ndi Toujeo ali ndi zosiyana zingapo.
Kodi pali kusiyana kotani pakati pa Tresiba ndi Toujeo?
Tresiba ndi dzina la insulin degludec. Ndi insulin yotenga nthawi yayitali yomwe imayendetsedwa tsiku lililonse ngati jakisoni pansi pa khungu (subcutaneous). Tresiba imapezeka ngati cholembera cha FlexTouch champhamvu m'mayunitsi 100 / mL ndi 200 mayunitsi / mL. Imapezekanso ngati vial 10 mL ya milingo ingapo.
Pambuyo pa kutumikiridwa ndi Tresiba, zotsatira zake zotsitsa shuga zimatha Maola 42 kapena zambiri. Tresiba amayamba kugwira ntchito ola limodzi ndipo amakhala ndi theka la moyo wa maola 25 pafupifupi. Zimatengera masiku atatu kapena anayi ogwiritsa ntchito tsiku ndi tsiku kuti Tresiba afike pamagulu osasunthika m'magazi (okhazikika).
Toujeo ndi dzina la insulin glargine. Ndi insulin yogwira ntchito kwa nthawi yayitali yomwe imayendetsedwa ngati jakisoni wa tsiku ndi tsiku. Toujeo amapezeka ngati cholembera cha 1.5 mL SoloStar kapena cholembera cha 3 mL Max SoloStar.
Zotsatira za Toujeo nthawi zambiri zimakhala pakati 24 ndi 36 maola pambuyo pa kayendetsedwe. Toujeo amayamba kugwira ntchito pasanathe maola asanu ndi limodzi atagwiritsa ntchito. Chifukwa chake, ndikutulutsa pang'onopang'ono insulin kuposa Tresiba. Ili ndi theka la moyo wazaka pafupifupi 19 ndipo imatenga masiku asanu ogwiritsira ntchito tsiku ndi tsiku kuti ifike pamlingo wofanana m'magazi.
Onse a Tresiba ndi Toujeo amatha kusungidwa kutentha kwa masiku 56 kapena milungu isanu ndi itatu.
| Kusiyana kwakukulu pakati pa Tresiba ndi Toujeo | ||
|---|---|---|
| Tresiba | Toujeo | |
| Gulu la mankhwala osokoneza bongo | Insulini Kutenga nthawi yayitali | Insulini Wotenga nthawi yayitali |
| Chizindikiro cha Brand / generic | Dzina Brand yekha | Dzina Brand yekha |
| Kodi dzina lachibadwa ndi liti? | Jekeseni wa insulini | Insulini glargine |
| Kodi mankhwalawa amabwera mwa mawonekedwe ati? | Njira yothetsera jekeseni | Njira yothetsera jekeseni |
| Kodi mulingo woyenera ndi uti? | Kuyambira mlingo ndi mlingo woyang'anira umadalira mtundu wa matenda ashuga, kuchuluka kwa shuga wamagazi, komanso zolinga zamankhwala | Kuyambira mlingo ndi mlingo woyang'anira umadalira mtundu wa matenda ashuga, kuchuluka kwa shuga wamagazi, komanso zolinga zamankhwala |
| Kodi mankhwalawa amatenga nthawi yayitali bwanji? | Kutalika kwanthawi yayitali pakulamulira kwamankhwala am'magazi | Kutalika kwanthawi yayitali pakulamulira kwamankhwala am'magazi |
| Ndani amagwiritsa ntchito mankhwalawa? | Akuluakulu ndi ana azaka 1 kapena kupitirira | Akuluakulu ndi ana azaka 6 kapena kupitilira apo |
Zomwe amathandizidwa ndi Tresiba ndi Toujeo
Tresiba ndi Toujeo ndi mabakiteriya am'badwo wachiwiri omwe amagwiritsidwa ntchito popititsa patsogolo shuga wamagazi mwa omwe ali ndi matenda ashuga. Insulini iliyonse imatha kuperekedwa kuti ichiritse mtundu wa 1 kapena Type 2 shuga. Monga ma insulins oyambira, amaperekedwa kamodzi tsiku lililonse kuti azitha kuwongolera shuga tsiku lonse. Anthu ena omwe ali ndi matenda ashuga amafunika kudya insulini kwakanthawi.
Ma insulini awa amatha kuthandiza kusungunutsa milingo ya shuga kwinaku ikuchepetsa Mulingo wa HbA1c . HbA1c imafotokozedwa ndi kuchuluka kwa shuga kwa miyezi iwiri kapena itatu.
| Mkhalidwe | Tresiba | Toujeo |
| Matenda a shuga Mtundu 1 | Inde | Inde |
| Matenda a shuga Mtundu 2 | Inde | Inde |
Kodi Tresiba kapena Toujeo ndiwothandiza kwambiri?
Tresiba ndi Toujeo ndi ma insulini awiri othandiza ochepetsa shuga m'magazi ndikukweza ma HbA1c. Poyerekeza ndi ma insulini othamanga mwachangu komanso achidule, ma insuliniwa amagwiritsidwa ntchito kamodzi tsiku lililonse kuti azitha kuwongolera glycemic. Insulini yothandiza kwambiri ndi yomwe imagwira ntchito bwino kwa inu kutengera malingaliro a dokotala wanu.
Malinga ndi kuwunika mwatsatanetsatane kofalitsidwa ndi Thandizo la Shuga , insulin degludec ndi insulin glargine ndizofanananso pakuwongolera magulu a shuga m'magazi . Mayeso 15 azachipatala osiyanasiyana poyerekeza ma insulini awiriwo adayesedwa. Panalibe kusiyana kwakukulu powerengera kuti insulini imatha kusintha ma glucose. Komabe, insulin degludec idapezeka kuti imayambitsa kuchepa kwa hypoglycemia, kapena kuchepa kwa shuga m'magazi.
Muwunikidwe mwatsatanetsatane wofalitsidwa ndi Matenda a shuga, kunenepa kwambiri ndi kagayidwe kake , maphunziro okwanira 70 adayerekezera zotsatira ndi chitetezo cha insulin degludec, insulin glargine, ndi insulin detemir. Insulitememememil ndi insulin yomwe imagwira ntchito ku Levemir. Zotsatira zidapeza kuti ma insulini onse atatu anali ofanana mofananira, ngakhale insulin degludec imayambitsa kuchepa kwa hypoglycemia. Odwala matenda ashuga omwe amatenga insulin detemir amakhala ochepa kunenepa kuposa ma insulins ena oyambira.
Funsani wothandizira zaumoyo wanu za mankhwala abwino a insulini. Mtundu umodzi wa insulin ungagwire ntchito bwino kutengera momwe mulili. Mankhwala ena angafunike kuti muchepetse kuchuluka kwa shuga wamagazi.
Kuphunzira ndi kuyerekezera mtengo wa Tresiba vs. Toujeo
Tresiba ili ndi mapulani ambiri a inshuwaransi, kuphatikiza Medicare. Pa botolo la 10 mL 100 unit / mL vial, mitengo yamtengo wapakati imatha kukhala $ 406.99. Kugwiritsa ntchito khadi yotsitsa kumatha kuthandiza kupulumutsa ndalama pama insulini akuchipatala ngakhale ndi inshuwaransi. Coupon ya SingleCare Tresiba ikhoza kutsitsa mtengo mpaka $ 343 kutengera mankhwala omwe akutenga nawo mbali.
Monga Tresiba, Toujeo imaphimbidwa ndi mapulani ambiri a inshuwaransi ngakhale pakhoza kukhala copay. Mtengo wapakati wa ndalama za Toujeo ukhoza kuyambira $ 341 mpaka $ 565 kutengera ngati mwapatsidwa Toujeo Max Solostar kapena Toujeo Solostar. Mtengo wokhala ndi khadi yotsitsa ya SingleCare ndi $ 217 ndi $ 301, motsatana.
| Tresiba | Toujeo | |
| Nthawi zambiri amakhala ndi inshuwaransi? | Inde | Inde |
| Nthawi zambiri amakhala ndi Medicare Part D? | Inde | Inde |
| Mlingo woyenera | Mlingo umadalira milingo ya shuga ndi zolinga zamankhwala | Mlingo umadalira milingo ya shuga ndi zolinga zamankhwala |
| Wopanga Medicare wamba | $ 5 mpaka $ 585 | $ 13 mpaka $ 447 |
| Mtengo wosakwatiwa | $ 343 + | $ 217- $ 301 |
Zotsatira zoyipa za Tresiba vs. Toujeo
Shuga wamagazi ochepa, kapena hypoglycemia, ndi chimodzi mwazotsatira zoyipa kwambiri za Tresiba ndi Toujeo. Zizindikiro za hypoglycemia imatha kukhala yofatsa kapena yayikulu kutengera momwe munthu amayankhira insulini, kuchuluka kwa insulini, komanso kadyedwe komanso zizolowezi zolimbitsa thupi. Zizindikiro za hypoglycemia zimaphatikizapo njala, kupepuka, kukwiya, kusokonezeka, ndi thukuta.
Tresiba ndi Toujeo amathanso kuyambitsa mayankho amalo a jakisoni, monga kufiyira, kutupa, kapena kuyabwa mozungulira dera la jakisoni. Komabe, zotsatirazi nthawi zambiri zimakhala zofewa ndipo zimatha zokha. Zotsatira zake zina zimaphatikizira matenda am'mapapo kapena chimfine (nasopharyngitis), kutupa m'manja kapena m'miyendo (edema), ndi kunenepa.
Tresiba akuti adayambitsa mutu komanso kutsegula m'mimba.
| Tresiba | Toujeo | |||
| Zotsatira zoyipa | Zoyenera? | Pafupipafupi | Zoyenera? | Pafupipafupi |
| Zochita zapa jekeseni | Inde | 4% | Inde | * |
| Matenda osokoneza bongo | Inde | 12% | Inde | * |
| Mutu | Inde | 12% | Ayi | - |
| Matenda opatsirana apamwamba | Inde | 12% | Inde | 10% |
| Nasopharyngitis | Inde | 24% | Inde | 13% |
| Kutsekula m'mimba | Inde | 6% | Ayi | - |
| Edema | Inde | 1% | Inde | * |
| Kulemera | Inde | * | Inde | * |
* sananene
Pafupipafupi sizidalira zomwe zimayesedwa pamutu. Izi sizingakhale mndandanda wathunthu wazovuta zomwe zingachitike. Chonde onani dokotala wanu kapena wothandizira zaumoyo kuti mudziwe zambiri.
Gwero: DailyMed ( Tresiba ), Tsiku Lililonse ( Toujeo )
Kuyanjana kwa mankhwala a Tresiba vs. Toujeo
Monga ma insulini ena, Tresiba ndi Toujeo amatha kulumikizana ndi mankhwala omwewo. Ma antihypertensives ena, monga ACE inhibitors ndi angiotensin II receptor blocking agents, amatha kuonjezera chiopsezo cha hypoglycemia akagwiritsa ntchito ndi Tresiba kapena Toujeo. Antidiabetic agents, monga dulaglutide, glyburide, ndi pioglitazone, amathanso kuwonjezera chiopsezo cha hypoglycemia ndi Tresiba kapena Toujeo.
Mankhwala monga corticosteroids ndi njira zakulera zitha kuchepetsa mphamvu ya Tresiba kapena Toujeo. Izi ndichifukwa choti mankhwalawa amatha kuwononga mphamvu yogwiritsa ntchito glucose yamphamvu. Mankhwala a antiadrenergic, monga beta-blockers, clonidine, ndi reserpine, amatha kubisa zizindikilo za hypoglycemia.
Kuwunika kwa glucose kungafunike Tresiba kapena Toujeo akagwiritsidwa ntchito limodzi ndi mankhwala ena omwe angakhudze kulolerana kwa shuga komanso kuchuluka kwa insulin.
| Mankhwala osokoneza bongo | Gulu la mankhwala osokoneza bongo | Tresiba | Toujeo |
| Enalapril Lisinopril Ramipril | Zoletsa za ACE | Inde | Inde |
| Losartan Olmesartan Irbesartan Zamgululi | Angiotensin II olandila othandizira | Inde | Inde |
| Dulaglutide Kutali Glyburide Pioglitazone Rosiglitazone | Maantibayotiki | Inde | Inde |
| Hydrocortisone Prednisone Zamgululi | Corticosteroids | Inde | Inde |
| Estradiol Ethinyl estradiol Drospirenone Norethindrone | Njira zolera zapakamwa | Inde | Inde |
| Atenolol Zamgululi Zamgululi Clonidine Guanethidine Onaninso | Othandizira antiadrenergic | Inde | Inde |
Funsani katswiri wa zamankhwala pazinthu zina zomwe zingagwiritsidwe ntchito ndi mankhwala.
Machenjezo a Tresiba ndi Toujeo
Hypoglycemia yoopsa imatheka mutatha kugwiritsa ntchito insulins monga Tresiba kapena Toujeo. Chiwopsezo cha hypoglycemia chachikulu chitha kuwonjezeka mwa iwo omwe ali ndi vuto la impso, kapena impso, komanso kuwonongeka kwa chiwindi, kapena chiwindi. Ma insulini monga Tresiba kapena Toujeo ayenera kugwiritsidwa ntchito ndi mankhwala oyenera komanso chitsogozo kuchokera kwa othandizira azaumoyo. Hypoglycemia imafunikira chithandizo chadzidzidzi ngati chakudya kapena glucagon.
Tresiba ndi Toujeo amatha kuyambitsa chidwi cha anthu ena. Mukakumana ndi zotupa zazikulu kapena kupuma movutikira, pitani kuchipatala mwachangu.
Hypokalemia, kapena potaziyamu wochepa , zitha kuchitika mukamagwiritsa ntchito Tresiba kapena Toujeo. Hypokalemia imatha kuopseza moyo ndipo imayambitsa zizindikilo monga kupuma movutikira, mayendedwe achilendo amtima (arrhythmia), kapena imfa.
Anthu ena angafunike kuyang'aniridwa ndi zizindikilo za kulephera kwa mtima ngati akugwiritsanso ntchito mankhwala a thiazolidinedione. Kugwiritsa ntchito mankhwalawa limodzi ndi Tresiba kapena Toujeo kumatha kuyambitsa kusungira kwamadzimadzi ndikuwonjezera kupwetekedwa mtima kwa mtima.
Funsani dokotala kapena wothandizira zaumoyo kuti akupatseni machenjezo ndi zodzitetezera.
Mafunso omwe amafunsidwa pafupipafupi za Tresiba vs. Toujeo
Tresiba ndi chiyani?
Tresiba ndi insulin yotenga nthawi yayitali yopangidwa ndi Novo Nordisk. Amaperekedwa kamodzi tsiku ndi tsiku kwa anthu omwe ali ndi matenda a shuga kuti azitha kuyendetsa bwino shuga. Tresiba imapezeka m'miyendo yambiri kapena zolembera za FlexTouch. Dzina lodziwika bwino la Tresiba ndi insulin degludec.
Toujeo ndi chiyani?
Toujeo ndi insulin yayitali yopangidwa ndi Sanofi-Aventis. Monga insulin yayitali, imangofunika kuperekedwa kamodzi tsiku lililonse kuti muchepetse shuga. Toujeo amabwera ngati cholembera cha SoloStar kapena cholembera cha Max SoloStar. Dzina lodziwika bwino la Toujeo ndi insulin glargine.
Kodi Tresiba ndi Toujeo ndi ofanana?
Onse awiri a Tresiba ndi Toujeo amathandizira kuchuluka kwa shuga wamagazi ndi milingo ya HbA1c mwa anthu omwe ali ndi matenda ashuga amtundu wa 1 kapena mtundu wachiwiri wa shuga. Onsewa amabayidwa pansi pa khungu (subcutaneously) kamodzi tsiku lililonse. Komabe, si mankhwala omwewo; Tresiba ili ndi insulin degludec pomwe Toujeo imakhala ndi insulin glargine. Ma insulini awa amakhala ndi nthawi zosiyanasiyana, pakati pazosiyana.
Kodi Tresiba kapena Toujeo ndibwino?
Tresiba amakhala ndi nthawi yayitali kuposa Toujeo; Tresiba amagwira ntchito maola oposa 42 pomwe Toujeo amagwira ntchito mpaka maola 36. Tresiba ayambanso kugwira ntchito mwachangu kuposa Toujeo; Tresiba amayamba kugwira ntchito ola limodzi pomwe Toujeo amayamba kugwira ntchito maola 6. Komabe, ma insulini onsewa ndi othandiza pochiza matenda ashuga.
Kuchiza bwino kumatengera mulingo wa insulin womwe mumagwiritsa ntchito. Mlingo ungafunike kusintha ngati insulini sikukusintha magalamu ambiri. Kuchuluka kwa hypoglycemia kumatha kutsika mwa iwo omwe amatenga Tresiba motsutsana ndi omwe amatenga Toujeo.
Kodi ndingagwiritse ntchito Tresiba kapena Toujeo ndili ndi pakati?
Tresiba kapena Toujeo ayenera kugwiritsidwa ntchito pokhapokha ngati ali ndi pakati kuposa maubwino ake. Pakadali pano, palibe maphunziro okwanira kudziwa ngati Tresiba kapena Toujeo atha kuvulaza mwana wosabadwa. Komabe, kuchuluka kwa shuga kosalamulirika panthawi yapakati (matenda opatsirana pogonana) ndi vuto lalikulu lomwe limatha kubweretsa zovuta ngati silinalandire chithandizo. Funsani wothandizira zaumoyo wanu ngati muli ndi pakati musanagwiritse ntchito Tresiba kapena Toujeo.
Kodi ndingagwiritse ntchito Tresiba kapena Toujeo ndi mowa?
Mowa umatha kusokoneza momwe shuga wamagazi amathandizira mthupi. Mowa umatha kuchepetsa momwe insulin imagwirira ntchito bwino m'thupi. Kumwa kwambiri mowa kumathandizanso ku hypoglycemia, kapena shuga wotsika kwambiri magazi. Kumwa mowa komanso hypoglycemia kumatha kubweretsa chisokonezo, mutu wopepuka, komanso mutu, zomwe zimafunikira chithandizo chamankhwala.
Kodi Tresiba ndi wofanana ndi NovoLog?
Tresiba si ofanana ndi NovoLog. Ngakhale onsewa ndi amisala, amagwira ntchito m'njira zosiyanasiyana. Tresiba ndi insulin yotenga nthawi yayitali pomwe NovoLog ndi insulin yochita mwachangu. NovoLog imayamba kugwira ntchito mwachangu kwambiri kuposa Tresiba, koma zotsatira zake zimangokhala kwa maola ochepa. Tresiba imayikidwa ngati insulini yamasamba yamasamba tsiku lililonse. NovoLog ikulimbikitsidwa ngati nthawi yodyera ya insulini.
Nthawi yabwino kutenga Tresiba ndi iti?
Tresiba imatha kutengedwa nthawi iliyonse ya tsiku. Mwachitsanzo, zitha kutengedwa m'mawa kapena usiku kutengera zomwe mumakonda komanso malingaliro a dokotala. Tresiba tikulimbikitsidwa kumwa kamodzi tsiku lililonse kwa akulu ndi ana. Kwa ana, Tresiba ayenera kumwedwa nthawi imodzimodzi tsiku lililonse.
Ndi insulini iti yomwe ndiyabwino kwambiri?
Insulini yabwino kwambiri ndi yomwe imagwira ntchito kwa inu komanso matenda anu. Zinthu zosiyanasiyana zimathandizira kudziwa insulini yabwino kwambiri, kuphatikiza kuchuluka kwa shuga, zina zomwe mungakhale nazo, mankhwala ena omwe mukumwa, komanso mtengo wa insulini . Ma insulini angapo angafunikirenso; Mwachitsanzo, insulini yogwira ntchito nthawi yayitali imatha kugwiritsidwa ntchito kamodzi tsiku lililonse pomwe insulini yothamanga imatha kugwiritsidwa ntchito pakudya pakufunika. Tresiba atha kukhala insulini yabwino kwambiri chifukwa wakhala nayo nthawi yayitali kwambiri. Ziribe kanthu kuti insulin imagwiritsidwa ntchito bwanji, kuwunika shuga kumalimbikitsidwa kuti mudziwe momwe insulin yolamuliridwayi ikugwirira ntchito.
