Pantoprazole vs. omeprazole: Kusiyana, kufanana, ndi zomwe zili zabwino kwa inu
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Pantoprazole ndi omeprazole ndi ma proton pump pump inhibitors (PPIs) omwe amagwiritsidwa ntchito pochiza kugaya kwam'mimba. Mankhwala onsewa amatha kugwiritsidwa ntchito pa matenda a gastroesophageal reflux (GERD), mtundu wopweteka kwambiri, komanso zotupa zotupa m'mimba. Amagwira ntchito pochepetsa kutsekemera kwa asidi m'mimba. Ngakhale pantoprazole ndi omeprazole ndi mankhwala ofanana, amakhalanso ndi zosiyana.
Kodi pali kusiyana kotani pakati pa pantoprazole ndi omeprazole?
Pantoprazole (makoponi a Pantoprazole) ndi dzina lodziwika bwino la Protonix ndipo pakadali pano imagulidwa ndi mankhwala okha. Ndivomerezedwa ndi FDA kuti ichiritse GERD kwa akulu ndi ana azaka 5 kapena kupitilira nthawi yayitali mpaka masabata asanu ndi atatu. Pantoprazole (zambiri za Pantoprazole) zimaperekedwa ngati piritsi lotulutsa mochedwa kapena kuyimitsidwa kwamadzi. Ikhoza kuperekedwanso ngati jakisoni (IV) kuchipatala kapena kuchipatala.
Omeprazole (Omeprazole coupons) imadziwikanso ndi dzina lake, Prilosec, ndipo itha kugulitsidwa ndi mankhwala kapena pamtengatenga. Imagwira chimodzimodzi ndi pantoprazole ngati PPI. Komabe, amavomerezedwanso ndi FDA kuti athetse zilonda zam'mimba, matenda a helicobacter pylori (H. pylori), ndi zilonda zam'mimba kuwonjezera pa GERD komanso zotupa zotupa. Omeprazole (zambiri za Omeprazole) zitha kuchiza GERD kwa akulu ndi ana chaka chimodzi kapena kupitilira apo. Zimabwera ngati kapule, kapiritsi, ndi kuyimitsidwa kwamadzi mochedwa.
| Kusiyana kwakukulu pakati pa pantoprazole ndi omeprazole | ||
|---|---|---|
| Pantoprazole | Omeprazole | |
| Gulu la mankhwala osokoneza bongo | Proton pump inhibitor (PPI) | Proton pump inhibitor (PPI) |
| Chizindikiro cha Brand / generic | Mtundu wa generic ulipo | Mtundu wa generic ulipo |
| Kodi dzina lachibadwa ndi liti? Kodi dzina lake ndi ndani? | Pantoprazole Protonix | Omeprazole Prilosec |
| Kodi mankhwalawa amabwera mwa mawonekedwe ati? | Piritsi lapakamwa, kutulutsidwa mochedwa Kuyimitsidwa pakamwa IV jakisoni / kulowetsedwa | Piritsi lapakamwa, kutulutsidwa mochedwa Kapisozi wamlomo, kutulutsidwa mochedwa Kuyimitsidwa pakamwa IV jakisoni / kulowetsedwa |
| Kodi mulingo woyenera ndi uti? | 40 mg kamodzi patsiku | 20 mg kamodzi patsiku |
| Kodi mankhwalawa amatenga nthawi yayitali bwanji? | Mpaka masabata 8 | 4 mpaka 8 milungu |
| Ndani amagwiritsa ntchito mankhwalawa? | Akuluakulu ndi ana azaka 5 kapena kupitilira apo | Akuluakulu ndi ana 1 chaka kapena kupitirira |
Zomwe zimathandizidwa ndi pantoprazole ndi omeprazole
Pantoprazole ndi omeprazole onse ndi ovomerezeka ndi FDA kuti athetse kutentha pa chifuwa kochokera ku GERD komanso eopiveitis. Ma PPI monga pantoprazole ndi omeprazole ndi amphamvu kuposa ma antiacid wamba, monga histamine (H2) blockers. Nthawi zambiri amapatsidwa chithandizo chanthawi yochepa osakhalitsa kupitilira masabata 8.
Pantoprazole ndi omeprazole amathanso kuchiza mikhalidwe ya hypersecretory yomwe imapangitsa kuti m'mimba mupange asidi wam'mimba wambiri. Matenda a Zollinger-Ellison ndi omwe amatha kuyambitsa matenda a asidi ndipo amatenga zotupa m'mapapo kapena duodenum (gawo loyamba la m'mimba).
Pantoprazole ndi omeprazole zithandizanso kuchiza matenda ena monga zilonda zam'mimba, zilonda zam'mimba kapena zam'mimba, ndi zilonda zam'mimba. Zilondazi nthawi zambiri zimayambitsidwa ndi matenda ochokera kubakiteriya otchedwa H. pylori. Ngakhale omeprazole imavomerezedwa kuchiza H. pylori kuphatikiza mankhwala ena, pantoprazole imagwiritsidwanso ntchito pamatendawa.
Ntchito zina zomwe sizigwiritsidwa ntchito pamankhwala onsewa ndi monga Barrett's esophagus and zilonda zomwe zimadza chifukwa chogwiritsa ntchito mankhwala osagwiritsa ntchito ma antisteroidal (NSAIDs).
| Mkhalidwe | Pantoprazole | Omeprazole |
| Matenda a Reflux a Gastroesophageal (GERD) | Inde | Inde |
| Kuphulika kwa Esophagitis | Inde | Inde |
| Matenda a Zollinger-Ellison | Inde | Inde |
| Mikhalidwe Hypersecretory | Inde | Inde |
| Zilonda zam'matumbo | Kutumiza | Inde |
| Zilonda zam'mimba | Kutumiza | Inde |
| Matenda a H. Pylori | Kutumiza | Inde |
| Khola la Barrett | Kutumiza | Kutumiza |
| Kudzimbidwa | Kutumiza | Kutumiza |
| NSAID zinayambitsa zilonda | Kutumiza | Kutumiza |
| Zilonda zam'mimba | Kutumiza | Kutumiza |
Mukufuna mtengo wabwino pa Omeprazole?
Lowani zamalamulo amtengo wa Omeprazole kuti mudziwe kuti mitengo isintha liti!
Pezani zidziwitso zamitengo
Kodi pantoprazole kapena omeprazole ndiyothandiza kwambiri?
Pantoprazole ndi omeprazole awonetsedwa kuti ndi othandiza pochiza GERD. Mu kusanthula meta omwe adaphatikiza maphunziro opitilira 40, zotsatira sizinapeze kusiyana kulikonse pakati pa ma PPI. Pantoprazole idapezeka kuti imagwiranso ntchito ngati omeprazole. Mayesero ena azachipatala omwe anali akhungu awiri adaphatikizanso ma PPI ena monga Nexium (esomeprazole) , lansoprazole (Prevacid), ndi rabeprazole (Aciphex).
Chimodzi kuphunzira Kuphatikizidwa pakuwunika kwa meta kunapeza kuti pantoprazole inali yothandiza kwambiri kuposa omeprazole pochiza zilonda zam'mimba. Zotsatira zomwe zaphatikizidwa kuchokera m'maphunziro a 5 pakuwunika kotsimikizira pamitengo yakuchiritsa. Ngakhale kuti pantoprazole imapezeka kuti imagwira ntchito kwambiri, mwina pakhoza kukhala zolakwika zina ndi dosing wosalingana.
Pantoprazole ndi omeprazole onse ndi ofanana ndi mankhwalawa ponena za mphamvu. Wina akhoza kusankhidwa kuposa mnzake kutengera momwe amathandizidwira komanso mtengo wamankhwala. Funsani dokotala kuti mudziwe PPI itha kukhala yabwinoko zanu.
Kuphunzira ndi kuyerekezera mtengo wa pantoprazole vs. omeprazole
Pantoprazole ndi mankhwala achibadwa omwe nthawi zambiri amakhala ndi Medicare komanso mapulani ambiri a inshuwaransi. Mtengo wapakati wamalonda wa pantoprazole ndi pafupifupi $ 522. Mutha kusungira zambiri ndi coupon ya SingleCare yomwe ingabweretse mtengo mpaka $ 28.
Pezani khadi yotsitsa ya SingleCare
Omeprazole ndi mankhwala achibadwa omwe nthawi zambiri amakhala ndi Medicare komanso mapulani ambiri a inshuwaransi. Mtengo wapakati wa omeprazole ndi pafupifupi $ 67.99. Ndi coupon ya SingleCare mutha kuyembekezera kulipira mozungulira $ 9-20 kwa 30, 20mg capsules.
| Pantoprazole | Omeprazole | |
| Nthawi zambiri amakhala ndi inshuwaransi? | Inde | Inde |
| Nthawi zambiri amadzazidwa ndi Medicare? | Inde | Inde |
| Mlingo woyenera | 40 mg (kuchuluka kwa 30) | 20 mg (kuchuluka kwa 30) |
| Wopanga Medicare wamba | Zimatengera dongosolo lanu la inshuwaransi | Zimatengera dongosolo lanu la inshuwaransi |
| Mtengo wosakwatiwa | $ 28 | $ 9-20 |
Zotsatira zoyipa za pantoprazole ndi omeprazole
Pantoprazole ndi omeprazole zimatha kuyambitsa mavuto monga kupweteka mutu, chizungulire, nseru, ndi kusanza. Zitha kuchititsanso mavuto ena am'mimba monga kutsekula m'mimba, kudzimbidwa, kupweteka m'mimba kapena m'mimba, komanso kupindika m'mimba kapena gasi. Zotsatira zina zomwe angakhale nazo zitha kuphatikizira kupweteka kwa mafupa, matenda opatsirana opuma, ndi asthenia kapena kusowa kwa mphamvu.
Omeprazole amathanso kuyambitsa mavuto monga asidi kubwerera, kupweteka kwa msana, ndi kutsokomola. Pantoprazole sanawerengedwe kuti awonetse zotsatirazi pafupipafupi.
| Pantoprazole | Omeprazole | |||
| Zotsatira zoyipa | Zoyenera? | Pafupipafupi | Zoyenera? | Pafupipafupi |
| Mutu | Inde | 12.2% | Inde | 7% |
| Nseru | Inde | 7% | Inde | 4% |
| Kutsekula m'mimba | Inde | 8.8% | Inde | 4% |
| Kudzimbidwa | Inde | <2% | Inde | awiri% |
| Kupweteka m'mimba | Inde | 6.2% | Inde | 5% |
| Kusanza | Inde | 4.3% | Inde | 3% |
| Kudzikweza | Inde | 3.9% | Inde | 3% |
| Chizungulire | Inde | 3% | Inde | awiri% |
| Ululu wophatikizana | Inde | 2.8% | Inde | N / A |
| Chitupa | Inde | <2% | Inde | awiri% |
| Kubwezeretsanso kwa acid | Ayi | - | Inde | awiri% |
| Matenda opatsirana apamwamba | Inde | N / A | Inde | awiri% |
| Kufooka / Kusowa mphamvu | Inde | N / A | Inde | 1% |
| Ululu wammbuyo | Ayi | - | Inde | 1% |
| Tsokomola | Ayi | - | Inde | 1% |
* Funsani dokotala kapena wamankhwala pazovuta zonse zomwe zingachitike.
Gwero Tsiku ndi Tsiku (pantoprazole) , Tsiku ndi Tsiku (omeprazole)
Kuyanjana kwa mankhwala a pantoprazole vs. omeprazole
Onse pantoprazole ndi omeprazole amatha kulumikizana ndi mankhwala omwewo. Onsewa amatha kulumikizana ndi mankhwala ochepetsa mphamvu ya kachilombo ka HIV monga rilpivirine, atazanavir, ndi saquinavir. Kumwa mankhwalawa palimodzi kungasinthe mphamvu ya mankhwala ochepetsa mphamvu ya kachilombo ka HIV ndikuwonjezera kawopsedwe kake. Kutenga pantoprazole kapena omeprazole ndi warfarin kumatha kuwonjezera ngozi yakutuluka magazi. Chifukwa chake, sayenera kutengedwa limodzi. Ngakhale clopidogrel silingakhudzidwe ndi pantoprazole, iyenera kupewedwa ndi omeprazole.
Pantoprazole ndi omeprazole amalumikizana ndi methotrexate, mankhwala a antimetabolite, ndipo amatha kuyambitsa chiopsezo chowopsa cha poyizoni ndi zotsatirapo.
Pantoprazole ndi omeprazole siziyenera kutengedwa nthawi yofanana ndi mchere wachitsulo ndi mankhwala ena omwe amadalira asidi m'mimba kuti ayamwe. Mankhwala ena omwe amadalira asidi m'mimba kuti ayamwe amaphatikizira mankhwala a chemotherapy monga erlotinib ndi dasatinib ndi ma antifungals monga ketoconazole ndi itraconazole.
Chifukwa ma PPI onsewa amapukusidwa m'chiwindi, amatha kulumikizana ndi mankhwala ena omwe amapangidwa ndi ma enzyme ofanana, kuphatikiza ma enzyme a CYP2C19. Komabe, malinga ndi Chizindikiro cha FDA , Zina mwa mankhwalawa, kuphatikizapo phenytoin, citalopram, ndi diazepam, sizinawonetsedwe kuti zimalumikizana kwambiri ndi pantoprazole. Komabe, ndikofunikira kukambirana mankhwala aliwonse omwe mumamwa ndi dokotala musanatenge PPI.
Ma PPI amatha kukhudza zotsatira za mayeso ena a labu. Ma PPI amadziwika kuti amayambitsa zonama poyesa mkodzo wa THC.
| Mankhwala osokoneza bongo | Gulu la Mankhwala | Pantoprazole | Omeprazole |
| Rilpivirine Nelfinavir Atazanavir Saquinavir Ritonavir | Mankhwala ochepetsa mphamvu ya kachilombo ka HIV | Inde | Inde |
| Warfarin | Wotsutsa | Inde | Inde |
| Clopidogrel | Chotupa | Ayi | Inde |
| Methotrexate | Antimetabolite | Inde | Inde |
| Mycophenolate mofetil Tacrolimus | Kuthamangitsidwa | Inde | Inde |
| Ketoconazole Chinthaka Voriconazole | Zosakanikirana | Inde | Inde |
| Erlotinib Dasatinib Nilotinib | Chemotherapy | Inde | Inde |
| Zipangizo fumarate Zipangizo gluconate Chitsulo sulphate Zipangizo zimathandizira | Mchere wachitsulo | Inde | Inde |
| Diazepam Midazolam | Benzodiazepine | Ayi | Inde |
| Phenytoin | Antiepileptic | Ayi | Inde |
| Clarithromycin Rifampin | Maantibayotiki | Inde | Inde |
| Citalopram | Kusankha serotonin reuptake inhibitor (SSRI) antidepressant | Ayi | Inde |
| St. John's Wort | Zitsamba | Inde | Inde |
* Uwu sungakhale mndandanda wathunthu wazomwe zingachitike mukamagwiritsa ntchito mankhwala osokoneza bongo. Funsani dokotala ndi mankhwala onse omwe mukumwa.
Machenjezo a pantoprazole ndi omeprazole
Pantoprazole ndi omeprazole sizovomerezeka kuti zigwiritsidwe ntchito kwakanthawi. Kugwiritsa ntchito nthawi yayitali kumalumikizidwa ndi chiopsezo chowonjezeka cha mafupa . Ngati muli ndi kufooka kwa mafupa, mungafune kuwunika kugwiritsa ntchito ma PPIs.
Deta ina yanena kuti mankhwala a PPI atha kuwonjezera chiopsezo cha zochitika zamtima monga matenda amtima ndi sitiroko. Komabe, a FDA ndi ena malipoti Limbikitsani zabwino za ma PPI kuposa izi.
Chifukwa pantoprazole ndi omeprazole zimakonzedwa m'chiwindi, zimatha kusinthidwa kapena kupewedwa mwa omwe ali ndi vuto la chiwindi.
Pantoprazole ndi omeprazole zitha kukulitsa kapena kuwonjezera chiopsezo cha systemic lupus erythematosus, matenda osowa mthupi okha.
Kuchiza ndi ma PPI kumatha kuwonjezera ngozi yotsekula m'mimba kuchokera ku matenda a Clostridium difficile. Izi zitha kukhala zowopsa kwa iwo omwe agonekedwa mchipatala kwanthawi yayitali.
Ma pantoprazole ndi omeprazole onse ali mgulu la Mimba la C ndipo atha kuvulaza mwana wosabadwa. Funsani dokotala kapena wothandizira zaumoyo ngati muli ndi pakati kapena mukuyamwitsa.
Mafunso omwe amafunsidwa pafupipafupi za pantoprazole vs. Omeprazole
Kodi pantoprazole ndi chiyani?
Pantoprazole (Protonix) ndi mankhwala a proton pump inhibitor (PPI) omwe amaperekedwa kuti athetse GERD komanso eopiveitis. Nthawi zambiri amatengedwa ngati piritsi yotulutsa mochedwa 40 mg mpaka milungu 8. Itha kumwedwa akuluakulu ndi ana azaka 5 kapena kupitilira apo.
Kodi omeprazole ndi chiyani?
Omeprazole (Prilosec) ndi mankhwala a PPI omwe amayenera kuchiza GERD ndi erosive esophagitis. Ndi FDA yomwe imavomerezedwa ndi matenda a H. pylori ndi zilonda zam'mimba kapena zam'mimba. Ikhoza kutengedwa ngati kapisozi wa 20 mg wochedwa kutulutsidwa kwa masabata 4 mpaka 8 mwa akulu ndi ana chaka chimodzi kapena kupitilira apo.
Kodi pantoprazole ndi omeprazole ndi ofanana?
Pantoprazole ndi omeprazole ali mgulu lomwelo la mankhwala. Komabe, ali ndi machitidwe ovomerezeka osiyanasiyana ndi zoyipa zake. Amabweranso m'mayendedwe osiyanasiyana.
Kodi pantoprazole kapena omeprazole ndiyabwino?
Pantoprazole ndi omeprazole onse ndi othandiza kwa GERD komanso eopiveitis. Mankhwala amodzi a PPI atha kusankhidwa kuposa ena kutengera momwe akuchiritsira komanso mtengo wa mankhwalawo.
Kodi ndingagwiritse ntchito pantoprazole kapena omeprazole ndili ndi pakati?
Pantoprazole ndi omeprazole sizovomerezeka kwa amayi apakati chifukwa cha chiopsezo cha fetus. Komabe, nthawi zina, maubwino ake amatha kuposa chiopsezo. Funsani dokotala ngati muli ndi pakati.
Kodi ndingagwiritse ntchito pantoprazole kapena omeprazole ndi mowa?
Kumwa mowa kumatha kuonjezera zovuta zina zomwe zimakhudzana ndi pantoprazole kapena omeprazole. Chifukwa chakuti kupweteka kwa mutu ndi mseru ndizofala zomwe zimachitika chifukwa cha ma PPI, zotsatirazi zimatha kuvuta pamene ma PPI atengedwa ndi mowa.
Kodi OTC omeprazole ndiyofanana ndi mankhwala?
Otheprazole ya pa-counter (OTC) imakhala ndi mankhwala omwewo komanso mphamvu ya omeprazole. OTC omeprazole itha kupezeka ngati OTC Prilosec popewa masiku 14 mapiritsi a 20 mg. Maphunzirowa sayenera kumwa kangapo miyezi inayi iliyonse.
Kodi ndiyenera kumwa Pantoprazole ndi Omeprazole nthawi yomweyo?
Pantoprazole ndi omeprazole sayenera kutengedwa nthawi yomweyo. Amagwira ntchito mofananira potseka kutulutsa kwa gastric acid m'mimba. Kuwatenga pamodzi kungapangitse kuti pakhale zovuta.
