Protonix vs. Nexium: Kusiyana, kufanana, ndi zomwe zili zabwino kwa inu
Mankhwala osokoneza bongo Vs. MnzanuKuwunika kwa mankhwala osokoneza bongo & kusiyana kwakukulu | Zinthu zothandizira | Mphamvu | Kuphunzira inshuwaransi ndi kufananiza mtengo | Zotsatira zoyipa | Kuyanjana kwa mankhwala | Machenjezo | FAQ
Protonix (pantoprazole) ndi Nexium (esomeprazole) ndi mankhwala awiri ogwiritsidwa ntchito kuthana ndi mavuto am'mimba, monga gastroesophageal Reflux matenda (GERD). GERD ndi matenda osachiritsika omwe amayamba m'mimba asidi akamabwerera m'mimba. Izi zitha kubweretsa zizindikilo monga kutentha pa chifuwa komanso zovuta zina monga kuphulika kwa m'mimba.
Protonix ndi Nexium ali m'gulu la mankhwala osokoneza bongo omwe amatchedwa proton pump inhibitors (PPIs). Amagwira ntchito potseka mapampu a proton m'mimba, omwe ali ndi udindo wopanga asidi. Mwakutero, Protonix ndi Nexium amathandizira kuchepetsa kupangika kwa asidi m'mimba.
Kodi pali kusiyana kotani pakati pa Protonix ndi Nexium?
Protonix, yopangidwa ndi Pfizer, ndiye dzina la pantoprazole. Ndi mankhwala akuchipatala omwe amagwiritsidwa ntchito pochizira zotupa m'mimba mwa akulu ndi ana azaka 5 kapena kupitilira apo. Imapezeka ngati piritsi yotulutsira mochedwa 20 mg ndi 40 mg, komanso kuyimitsidwa kwamadzi mg 40 mg. Nthawi zina, Protonix itha kuperekedwa ngati jakisoni wamitsempha (IV).
Nexium amapangidwa ndi AstraZeneca ndipo ndiye dzina la esomeprazole. Amapezeka ngati mankhwala akuchipatala kapena owonjezera (OTC) omwe amagwiritsidwa ntchito pochizira GERD kwa akulu, ana, ndi makanda azaka chimodzi kapena kupitilira apo. Mosiyana ndi Protonix, Nexium imabwera ngati 20 mg ndi 40 mg yotulutsa kapule. Nexium imapezekanso ngati 2.5 mg, 5 mg, 10 mg, 20 mg, ndi 40 mg kuyimitsidwa kwamadzi.
| Kusiyana kwakukulu pakati pa Protonix ndi Nexium | ||
|---|---|---|
| Protonix | Nexium | |
| Gulu la mankhwala osokoneza bongo | Proton pump inhibitor (PPI) | Proton pump inhibitor (PPI) |
| Chizindikiro cha Brand / generic | Ma brand ndi generic amapezeka | Ma brand ndi generic amapezeka |
| Kodi dzina lachibadwa ndi liti? | Pantoprazole | Esomeprazole |
| Kodi mankhwalawa amabwera mwa mawonekedwe ati? | Piritsi lotulutsidwa mochedwa Granules paketi kuyimitsidwa madzi Mtsempha wa magazi jekeseni | Capsule yotulutsidwa mochedwa Granules paketi kuyimitsidwa madzi Mtsempha wa magazi jekeseni |
| Kodi mulingo woyenera ndi uti? | 40 mg kamodzi patsiku | 20 kapena 40 mg kamodzi patsiku |
| Kodi mankhwalawa amatenga nthawi yayitali bwanji? | Mpaka masabata 8 | Masabata 4 mpaka 8 kutengera momwe akuchiritsira |
| Ndani amagwiritsa ntchito mankhwalawa? | Akuluakulu ndi ana azaka 5 kapena kupitilira apo | Akuluakulu, ana, ndi makanda azaka chimodzi kapena kupitilira apo |
Zinthu zothandizira Protonix ndi Nexium
Protonix ndi Nexium atha kuchiza GERD ndimikhalidwe yokhudzana ndi GERD, monga acid reflux (kutentha pa chifuwa). Mankhwala onsewa amavomerezedwanso ndi FDA kuti athetse matenda opatsirana m'mimba, kapena kutupa kwamkati mwake.
Nexium ndi FDA yomwe imavomerezedwa kuchiza matenda a Helicobacter pylori (H. pylori). Matenda amtunduwu amayamba mabakiteriya a H. pylori akamatengera m'mimba, zomwe zimatha kuyambitsa zilonda zam'mimba. Kuphatikiza pa zilonda zoyambitsidwa ndi H. pylori, Nexium imatha kuletsa ngozi ya zilonda zomwe zimakhudzana ndi mankhwala osagwiritsa ntchito ma antisteroidal (NSAIDs).
Protonix ndi Nexium zitha kugwiritsidwa ntchito pochiza matenda amisala, monga matenda a Zollinger-Ellison. Izi zimadziwika ndikuchulukitsa kwa asidi m'mimba. Protonix ndi Nexium itha kugwiritsidwanso ntchito kuthana ndi zilonda zam'mimba, zomwe zimaphatikizapo zilonda zam'mimba ndi zam'mimba.
Protonix ndi Nexium zimangolimbikitsidwa kuti zigwiritsidwe ntchito kwakanthawi kochepa, kapena mpaka milungu eyiti nthawi zambiri.
| Mkhalidwe | Protonix | Nexium |
| Matenda a reflux a gastroesophageal (GERD) | Inde | Inde |
| Kupweteka kwa m'mimba | Inde | Inde |
| Mikhalidwe Hypersecretory | Inde | Inde |
| Matenda a H. pylori | Kutumiza | Inde |
| Kuchepetsa chiwopsezo cha zilonda zam'mimba zokhudzana ndi NSAID | Kutumiza | Inde |
| Zilonda zam'matumbo | Kutumiza | Kutumiza |
| Zilonda zam'mimba | Kutumiza | Kutumiza |
| Kutentha pa chifuwa | Kutumiza | Inde |
Kodi Protonix kapena Nexium ndiyothandiza kwambiri?
Mayesero azachipatala awonetsa kuti pantoprazole ndi esomeprazole ndizothandizanso chimodzimodzi. Chiyeso chimodzi chachipatala poyerekeza mphamvu wa 40 mg wa pantoprazole mpaka 40 mg wa esomeprazole mwa odwala omwe ali ndi GERD. Pafupifupi odwala 580 adasinthidwa mwachisawawa kuti alandire pantoprazole kapena esomeprazole pamasabata 4, 8, kapena 12. Kukhululukidwa kwathunthu kwa GERD kunakwaniritsidwa ndi PPI onse pamitengo yofananira.
Mu kuyesedwa kwamankhwala kosawoneka bwino, khungu lakhungu, mphamvu ya pantoprazole ndi esomeprazole idafaniziridwa pochiza GERD. Pafupifupi odwala 200 adasinthidwa mwachisawawa kuti alandire 40 mg ya pantoprazole tsiku lililonse kapena 40 mg ya esomeprazole tsiku lililonse. Ma PPI onsewa amapezeka mofananamo ndi chitetezo chofananira komanso kulolerana.
Funsani wothandizira zaumoyo kuti akupatseni chithandizo chabwino kwambiri. Wosamalira kwanu wamkulu angakutumizireni kwa dokotala yemwe amadziwika ndi gastroenterology kuti mukalandire malangizo ena azachipatala.
Kuphunzira ndi kuyerekezera mtengo wa Protonix vs. Nexium
Ma Medicare ambiri ndi mapulani a inshuwaransi amatenga mtundu wa Protonix, pantoprazole. Ma copare a Medicare amatha kuyambira $ 0 mpaka $ 17 pa pantoprazole. Popanda inshuwaransi, mtengo wapakati wa Protonix ndi $ 522. Komabe, ndi coupon ya Protonix yochokera ku SingleCare, mtengo wake ndi pafupifupi $ 11.
Ma Medicare ena ndi mapulani a inshuwaransi atha kubisa Nexium kapena mtundu wake, esomeprazole. Mankhwala a Medicare a esomeprazole amatha kuyambira $ 1 mpaka $ 41. Mtengo wamalonda wa Nexium ndi $ 478 kutengera kuchuluka ndi mphamvu zomwe zaperekedwa. Ndi coupon ya SingleCare Nexium, mtengo wamba utha kutsitsidwa mpaka pafupifupi $ 27.
| Protonix | Nexium | |
| Nthawi zambiri amakhala ndi inshuwaransi? | Inde, monga mtundu wamba | Inde, monga mtundu wamba |
| Nthawi zambiri amakhala ndi Medicare Part D? | Inde, monga mtundu wamba | Inde, monga mtundu wamba |
| Kuchuluka | Mapiritsi 30 (40 mg) | Mapiritsi 30 (40 mg) |
| Wopanga Medicare wamba | $ 0 mpaka $ 17 | $ 1– $ 41 |
| Mtengo wosakwatiwa | $ 11 + | $ 27 + |
Zotsatira zoyipa za Protonix vs. Nexium
Zotsatira zoyipa kwambiri za Protonix ndi kupweteka mutu, kutsekula m'mimba, nseru, kupweteka m'mimba, kusanza, mpweya, chizungulire, ndi kupweteka kwamagulu.
Zotsatira zoyipa za Nexium zimaphatikizapo kupweteka mutu, kutsegula m'mimba, mseru, mpweya, kupweteka m'mimba, kudzimbidwa, ndi pakamwa pouma.
Zotsatira zoyipa za ma PPI nthawi zambiri zimalumikizidwa ndikugwiritsidwa ntchito kwanthawi yayitali. Zotsatira zoyipa zimatha kuphatikizira kufooka kwa mafupa, kufooka kwa vitamini B12, komanso kutsika kwa magnesium (hypomagnesemia).
| Protonix | Nexium | |||
| Zotsatira zoyipa | Zoyenera? | Pafupipafupi | Zoyenera? | Pafupipafupi |
| Mutu | Inde | 12% | Inde | %1% |
| Kutsekula m'mimba | Inde | 9% | Inde | %1% |
| Kudzimbidwa | Inde | <2% | Inde | %1% |
| Pakamwa pouma | Inde | <2% | Inde | %1% |
| Nseru | Inde | 7% | Inde | %1% |
| Kupweteka m'mimba | Inde | 6% | Inde | %1% |
| Kusanza | Inde | 4% | Inde | <1% |
| Chizungulire | Inde | 3% | Inde | <1% |
| Gasi | Inde | 4% | Inde | %1% |
| Ululu wophatikizana | Inde | 3% | Ayi | - |
Pafupipafupi sizidalira zomwe zimayesedwa pamutu. Izi sizingakhale mndandanda wathunthu wazovuta zomwe zingachitike. Chonde onani dokotala wanu kapena wothandizira zaumoyo kuti mudziwe zambiri.
Gwero: DailyMed ( Protonix ), Tsiku Lililonse ( Nexium )
Kuyanjana kwa mankhwala a Protonix vs. Nexium
Protonix ndi Nexium, monga ma PPI ena, amalumikizana ndi mankhwala omwewo. Ma PPIwa amayenera kuyang'aniridwa kapena kupewa ndi mankhwala ena omwe amadalira acidity ya m'mimba kuti ayamwe. Mankhwala omwe amadalira acidity ya m'mimba kuti ayamwe amaphatikizira mchere wachitsulo, erlotinib, ketoconazole, ndi mycophenolate mofetil.
Protonix ndi Nexium amathanso kulumikizana ndi mankhwala ochepetsa mphamvu ya kachilombo ka HIV, kapena mankhwala omwe nthawi zambiri amagwiritsidwa ntchito pochiza HIV. Ma PPI amatha kukulitsa kapena kuchepetsa kuchuluka kwamagazi a mankhwala ochepetsa mphamvu ya kachilombo ka HIV, omwe angapangitse chiopsezo chowonjezeka cha poyizoni kapena kuchepa kwa mphamvu ya mankhwala ochepetsa mphamvu ya kachilombo ka HIV.
Kugwiritsa ntchito Protonix kapena Nexium ndi warfarin kumatha kuwonjezera ngozi yakutaya magazi.
Nexium iyenera kuyang'aniridwa kapena kupewa ndi diazepam chifukwa imatha kuonjezera kuchuluka kwa magazi a diazepam ndikuwonjezera chiopsezo chowopsa. Kugwiritsanso ntchito Nexium ndi clopidogrel limodzi kuyeneranso kupewa. Nexium imatha kuchepetsa momwe clopidogrel imagwirira ntchito mthupi, zomwe zitha kuwonjezera ngozi yamagazi.
| Mankhwala osokoneza bongo | Mtundu wa mankhwala osokoneza bongo | Protonix | Nexium |
| Atazanavir Rilpivirine Nelfinavir Saquinavir | Mankhwala ochepetsa mphamvu ya kachilombo ka HIV | Inde | Inde |
| Ketoconazole | Zosakanikirana | Inde | Inde |
| Chitsulo sulphate Zipangizo gluconate Zipangizo fumarate | Mchere wachitsulo | Inde | Inde |
| Mycophenolate mofetil Methotrexate | Wodwalitsa | Inde | Inde |
| Erlotinib | Chemotherapy | Inde | Inde |
| Digoxin | Mtima glycoside | Inde | Inde |
| Warfarin | Wotsutsa | Inde | Inde |
| Diazepam | Benzodiazepine | Ayi | Inde |
| Clopidogrel | Chotupa | Ayi | Inde |
Funsani katswiri wa zamankhwala pazinthu zina zomwe zingagwiritsidwe ntchito ndi mankhwala
Machenjezo a Protonix ndi Nexium
Kugwiritsa ntchito ma PPIs kwa nthawi yayitali kumatha kubweretsa chiopsezo chowonjezeka cha mafupa, makamaka mwa anthu omwe adapezeka kale kuti ali ndi kufooka kwa mafupa. Kuchuluka kwa mafupa amfupa kungafunike kuyang'aniridwa nthawi yayitali ndi ma PPI.
Odwala ena akumanapo ndi tubulointerstitial nephritis (TIN) akamamwa Protonix kapena Nexium. Nephritis ndikutupa kwa impso, komwe kumatha kubweretsa kuchepa kwa impso.
Kugwiritsa ntchito ma PPIs kumatha kulumikizidwa ndi chiopsezo chowonjezeka cha matenda otsekula m'mimba a Clostridium difficile. Anthu omwe amatsekula m'mimba mosalekeza angafunike kuyang'aniridwa, makamaka kuchipatala.
Kutenga Protonix kapena Nexium kumatha kuonjezera chiopsezo cha kuchepa kwa magazi a magnesium (hypomagnesemia) kapena vitamini B12 (kusowa kwa vitamini B12). Pali chiopsezo chowonjezeka cha hypomagnesemia ndi kuchepa kwa vitamini B12 kwa iwo omwe ali ndi chithandizo cha nthawi yayitali ndi ma PPIs.
Funsani wothandizira zaumoyo wanu kuti akuchenjezeni ndi zodzitetezera musanatenge PPI.
Mafunso omwe amafunsidwa pafupipafupi za Protonix vs. Nexium
Kodi Protonix ndi chiyani?
Protonix ndi mankhwala okhawo a PPI omwe amagwiritsidwa ntchito kwambiri pochizira matenda opatsirana omwe amapezeka ndi GERD. Protonix imapezeka ngati piritsi lotulutsira mochedwa komanso kuyimitsidwa kwamadzi. Dzina lodziwika bwino la Protonix ndi pantoprazole.
Nexium ndi chiyani?
Nexium ndi mankhwala a PPI omwe amagwiritsidwa ntchito pochizira acid reflux ndi kutentha pa chifuwa, komanso kuphulika kwa mitsempha yokhudzana ndi GERD. Imapezeka ndi mankhwala kapena cholembera. Nexium makamaka imabwera ngati kapisozi wotulutsidwa mochedwa kapena kuyimitsidwa kwamadzi. Dzina lodziwika bwino la Nexium ndi esomeprazole.
Kodi Protonix ndi Nexium ndizofanana?
Protonix ndi Nexium ndi mankhwala awiri a PPI omwe amatha kuchiza GERD, hypersecretory, ndi zilonda zam'mimba. Komabe, ali ndi zinthu zosiyanasiyana zogwira ntchito ndipo amabwera mosiyanasiyana. Protonix imakhala ndi pantoprazole ndipo Nexium imakhala ndi esomeprazole. Protonix imatha kuchiza GERD mwa akulu ndi ana azaka 5 kapena kupitilira pomwe Nexium imatha kuchiza GERD mwa akulu, ana, ndi makanda azaka chimodzi kapena kupitilira apo.
Kodi Protonix kapena Nexium ndiyabwino?
Protonix ndi Nexium ndizofanana mofananira. PPI yoyenera kwambiri idzadziwika malinga ndi msinkhu, matenda, mtengo, inshuwaransi, ndi mankhwala ena omwe akutengedwa.
Kodi nditha kugwiritsa ntchito Protonix kapena Nexium ndili ndi pakati?
Protonix kapena Nexium ikhoza kukhala yotetezeka kutenga mukakhala ndi pakati. Komabe, ayenera kugwiritsidwa ntchito pokhapokha phindu lingapitirire pachiwopsezo. Pakadali pano, palibe kafukufuku wokwanira wosonyeza kuti Protonix kapena Nexium ndiyabwino kugwiritsa ntchito nthawi yapakati. Funsani wothandizira zaumoyo kuti akalandire chithandizo chamankhwala abwino kwambiri a GERD ali ndi pakati.
Kodi ndingagwiritse ntchito Protonix kapena Nexium ndi mowa?
Ngakhale kuti mowa sudziwika kuti ungagwirizane ndi Protonix kapena Nexium, umatha kukulitsa asidi reflux ndi zizindikiritso za kutentha kwa mtima kwa anthu ena. Kumwa mowa kumatha kukhala kotetezeka pang'ono mukamamwa Protonix kapena Nexium, koma sikokwanira.
Kodi pulogalamu yotulutsa proton yothandiza kwambiri ndi iti?
PPI yothandiza kwambiri imadalira momwe akuchiritsira, kuchuluka kwa PPI, ndi mankhwala ena omwe munthu akhoza kumwa. Mtengo wa PPI uyeneranso kuganiziridwa posankha njira yabwino kwambiri.
Kodi ndingatenge chiyani m'malo mwa Nexium?
Nexium (esomeprazole) ndi proton pump inhibitor. Ma proton pump inhibitors ena ndi Prilosec (omeprazole), Prevacid (lansoprazole), Aciphex (rabeprazole), ndi Protonix (pantoprazole). Ngati zizindikiro za GERD sizikusintha ndi PPI, wothandizira zaumoyo atha kulangiza mankhwala a H2 blocker m'malo mwake. Zitsanzo za ma H2 blockers ndi Pepcid (famotidine), Zantac (ranitidine), ndi Tagamet (cimetidine).
Kodi Nexium ingapangitse kuti reflux iwonongeke?
Nexium imagwiritsidwa ntchito pochizira asidi Reflux. Kusiya chithandizo cha Nexium koyambirira kuposa momwe adalangizire othandizira azaumoyo angapangitsire kubwerera kwa zizindikiro za Reflux. Nexium mwina singagwire ntchito chimodzimodzi kwa aliyense. Ngati zizindikiro sizikusintha ndi Nexium, njira zina zamankhwala zitha kulimbikitsidwa.
