Waukulu >> Mankhwala Osokoneza Bongo Vs. Mnzanu >> Tramadol vs. Hydrocodone: Kusiyana, kufanana, ndi iti yomwe ili yabwino kwa inu

Tramadol vs. Hydrocodone: Kusiyana, kufanana, ndi iti yomwe ili yabwino kwa inu

Mankhwala osokoneza bongo Vs. Mnzanu

Tramadol ndi hydrocodone ndi mankhwala awiri omwe amagwiritsidwa ntchito pochiza zowawa zomwe sizimasulidwa mosavuta ndi analgesic yopanda opioid. Mankhwala onsewa amatha kupweteketsa kwambiri pambuyo pochitidwa opaleshoni kapena matenda osatha monga khansa. Komabe, pamavuto ambiri, mankhwala osagwiritsa ntchito opioid amayesedwa kaye koyamba.

Onse tramado l ndi hydrocodone amagwira ntchito pomangiriza ma mu opioid receptors kuti asinthe momwe munthu amayankhira akapweteka. Monga ma opioid akuchipatala, ndi amphamvu kwambiri kuposa momwe mungachepetsere kupweteka kwapafupipafupi. Chifukwa chake, mankhwalawa amafunika kukacheza ndi dokotala kuti akawone kupweteka kwanu.

Kodi pali kusiyana kotani pakati pa Tramadol ndi Hydrocodone?

Tramadol ndi dzina loti Ultram, Ultram ER, ndi ConZip. Ndi mankhwala osokoneza bongo a Pulogalamu IV malinga ndi DEA zomwe zikutanthauza kuti atha kuzunzidwa. Ngakhale imamangiriridwa mu ma opioid receptors, imathanso kuwonjezera ntchito za ma neurotransmitter ena aubongo monga norepinephrine ndi serotonin.

Hydrocodone ndi dzina lodziwika bwino la Zohydro ER ndi Hysingla ER. Hydrocodone imagwiritsidwanso ngati piritsi limodzi ndi acetaminophen pansi pa mayina a Vicodin kapena Lortab. Mosiyana ndi tramadol, hydrocodone ndi mankhwala omwe ali mu Gawo II la DEA omwe ali pachiwopsezo chachikulu chakuzunzidwa.

Kusiyana kwakukulu pakati pa Tramadol ndi Hydrocodone
	Zamgululi	Hydrocodone
Gulu la mankhwala osokoneza bongo	Opioid	Opioid
Chizindikiro cha Brand / generic	Mtundu wa generic ulipo	Mtundu wa generic ulipo
Kodi dzina lachibadwa ndi liti? Kodi dzina lake ndi ndani?	Zowonjezera: Tramadol Mtundu: Ultram, Ultram ER	Zowonjezera: Hydrocodone Mtundu: Zohydro ER, Hysingla ER, Vicodin (wophatikizidwa ndi acetaminophen), Lortab (wophatikizidwa ndi acetaminophen), Norco (wophatikizidwa ndi acetaminophen)
Kodi mankhwalawa amabwera mwa mawonekedwe ati?	Piritsi lapakamwa Piritsi lapakamwa, kutulutsa kwina Makapisozi apakamwa Kuyimitsidwa pakamwa	Piritsi lapakamwa Piritsi lapakamwa, kutulutsa kwina Makapisozi apakamwa Yankho pakamwa
Kodi mulingo woyenera ndi uti?	Ultram: 50 mpaka 100 mg maola 4 kapena 6 aliwonse pakufunika kutero Ultram ER: 100 mg maola 24 aliwonse	Zohydro ER: 10 mg maola 12 aliwonse Hysingla ER: 20 mg maola 24 aliwonse Vicodin, Lortab, Norco (kuphatikiza ndi acetaminophen): 5 mpaka 10 mg maola 4 kapena 6 aliwonse pakufunika
Kodi mankhwalawa amatenga nthawi yayitali bwanji?	Tsiku ndi tsiku momwe zingafunikire. Kutalika kwa chithandizo kumadalira malangizo a dokotala wanu.	Tsiku ndi tsiku momwe zingafunikire. Kutalika kwa chithandizo kumadalira malangizo a dokotala wanu.
Ndani amagwiritsa ntchito mankhwalawa?	Akuluakulu azaka 18 kapena kupitilira apo	Akuluakulu azaka 18 kapena kupitilira apo

Zomwe zimathandizidwa ndi Tramadol ndi Hydrocodone

Tramadol ndi hydrocodone onse amawonetsedwa pakusamalira ululu. Nthawi zambiri amalembedwa ngati muli ndi ululu wopweteka kwambiri, makamaka chifukwa cha khansa. Mankhwala onsewa amagwiritsidwanso ntchito kupweteka pambuyo povulala komanso kuchitidwa opaleshoni.

Mkhalidwe	Zamgululi	Hydrocodone
Kupweteka pang'ono	Inde	Inde
Kupweteka kosatha	Inde	Inde
Ululu wovulala kapena pambuyo pochitidwa opaleshoni	Inde	Inde
Khansa	Inde	Inde

Kodi Tramadol kapena Hydrocodone ndiyothandiza kwambiri?

Tramadol ndi hydrocodone onse ndi mankhwala opioid opangira ululu. Pali maphunziro angapo omwe akuyerekezeratu momwe amathandizira. Chifukwa hydrocodone ndi gawo lachiwiri la opiate, itha kuonedwa ngati yamphamvu ngakhale imabwera ndi kuthekera kozunza. Tramadol itha kukhala ndi vuto locheperako komanso zovuta zoyipa.

Mmodzi kuphunzira zambiri , tramadol yokhala ndi acetaminophen idafaniziridwa ndi hydrocodone yokhala ndi acetaminophen mwa odwala omwe akumva kuwawa ndi bondo. Odwala pafupifupi 400 adagawika m'magulu awiri akulandila mankhwala amodzi kapena enawo. Zotsatira zapeza kuti mankhwala onsewa amapatsa ululu wofananira mkati mwa maola anayi motsutsana ndi placebo.

Mwa wina mayesero azachipatala , hydrocodone yokhala ndi acetaminophen idafanizidwa ndi tramadol mwa odwala 68. Odwalawa anali atafika ku dipatimenti yodzidzimutsa ya ululu waminyewa m'mfundo zawo, mafupa, kapena minofu. Zotsatira zapeza kuti hydrocodone yokhala ndi acetaminophen imapereka mpumulo wopweteka kwambiri poyerekeza ndi tramadol kutengera zowawa zomwe zimakhala ndi analog scale (VAS).

Mu kuyesedwa kosawona , hydrocodone yokhala ndi acetaminophen idafaniziridwa ndi tramadol mwa odwala 118 omwe ali ndi zowawa za khansa. Tramadol idawonetsa kupumula kwa odwala 62% poyerekeza ndi 56.5% ya odwala omwe ali ndi hydrocodone. Komabe, kupweteka kwa ululu kunali kofanana m'magulu onsewa. Tramadol idapezekanso kuti imatulutsa zovuta zoyipa motsutsana ndi hydrocodone.

Kaya mwapatsidwa tramadol kapena hydrocodone zimadalira kwambiri mtundu wa ululu wanu. Pofufuza zowawa zanu, adotolo adzawona mbiri yanu yonse yazachipatala, mbiri yakusokoneza bongo, ndi mankhwala aliwonse omwe angayambitse kuyanjana kwa mankhwala. Chifukwa chake, mankhwala opweteka amakhala apadera kwambiri ndipo amafunikira kufunsa kwa dokotala kuti adziwe omwe angakuthandizeni kwambiri.

Kuphatikiza ndi kuyerekezera mtengo kwa Tramadol vs. Hydrocodone

Tramadol imapezeka ngati mankhwala achibadwa. Amakhala ndi Medicare komanso mapulani ambiri a inshuwaransi. Mtengo wapakati wopezeka mapiritsi makumi asanu ndi limodzi a 50 mg tramadol ali pafupifupi $ 40. Mumasunga zambiri ndi coupon ya SingleCare ya generic tramadol ku pharmacy yakwanuko.

Hydrocodone ndi mankhwala achibadwa omwe nthawi zambiri amapangidwa ndi Medicare komanso mapulani ambiri a inshuwaransi. Mtengo wa hydrocodone umasiyana pakati pa mapulani a inshuwaransi osiyanasiyana. Norco yomwe imakhala ndi hydrocodone ndi acetaminophen imatha kuthamanga $ 317. Ndi coupon ya SingleCare, mutha kuyembekezera kusunga zambiri pamankhwala a hydrocodone okhala ndi acetaminophen.

	Zamgululi	Hydrocodone
Nthawi zambiri amakhala ndi inshuwaransi?	Inde	Inde
Nthawi zambiri amakhala ndi Medicare?	Inde	Inde
Mlingo woyenera	Mapiritsi 50 mg (kupezeka kwa 60) Zimatengera mankhwala akuchipatala	Mapiritsi 5-325 mg (kupezeka kwa 100) Zimatengera mankhwala akuchipatala
Wopanga Medicare wamba	$ 40	$ 317
Mtengo wosakwatiwa	$ 15	$ 18

Zotsatira zoyipa za Tramadol ndi Hydrocodone

Tramadol ndi hydrocodone zimatha kuyambitsa zovuta zina. Chifukwa zonsezi zimakhudza dongosolo lamanjenje lamkati (CNS), zimatha kuyambitsa chizungulire, kugona, komanso kutopa. Mankhwalawa amathanso kuyambitsa zovuta zam'mimba monga kudzimbidwa kapena kupweteka m'mimba. Nseru, kusanza, mkamwa mouma, ndi kupweteka kwa mutu ndizo zotsatira zina zomwe zimagawidwa.

Tramadol imathanso kutsekula m'mimba, kudzimbidwa, ndi thukuta mwa anthu ena. Mbali inayi, hydrocodone imathanso kuyambitsa madzimadzi (edema) kapena kupindika kwa minofu mwa anthu ena. Zonsezi, zovuta zoyipa zimatha kupezeka pakati pa mankhwalawa popeza ali mgulu lomwelo.

Zotsatira zina zosowa koma zoyipa za tramadol ndi hydrocodone zitha kuphatikizira nkhawa, kukhumudwa, kapena zovuta zina zamaganizidwe. Zomwe zimayambitsa matendawa ndizotheka ndipo zimatha kuphatikiza kuthamanga, kuthamanga, ndi kupweteka pachifuwa.

	Zamgululi	Hydrocodone
Zotsatira zoyipa	Zoyenera?	Pafupipafupi	Zoyenera?	Pafupipafupi
Kudzimbidwa	Inde	24-46%	Inde	khumi ndi chimodzi%
Chizungulire	Inde	26-33%	Inde	3%
Nseru	Inde	24-40%	Inde	10%
Mutu	Inde	18-32%	Inde	4%
Kusinza	Inde	16-25%	Inde	5%
Kusanza	Inde	9-17%	Inde	3%
Kuyabwa (Pruritus)	Inde	8-11%	Inde	3%
Kufooka	Inde	6-12%	Inde	4%
Kutuluka thukuta	Inde	6-9%	Ayi	-
Kudzimbidwa	Inde	5-13%	Ayi	-
Pakamwa pouma	Inde	5-10%	Inde	3%
Kutsekula m'mimba	Inde	5-10%	Ayi	-
Edema	Ayi	-	Inde	1%
Matenda opuma	Ayi	-	Inde	1%
Kupweteka kwa minofu	Ayi	-	Inde	1%
Ululu wammbuyo	Ayi	-	Inde	1%

* Funsani dokotala kapena wamankhwala pazovuta zonse zomwe zingachitike.

Gwero Tsiku ndi Tsiku (Tramadol HCl) , Tsiku ndi Tsiku (Zohydro ER) .

Kuyanjana kwa mankhwala a Tramadol vs. Hydrocodone

Tramadol ndi hydrocodone zimayanjananso chimodzimodzi ndi mankhwala ena. Chifukwa zimapukusidwa m'chiwindi, zimakonda kuyanjana ndi mankhwala ena omwe amakhudza michere ya chiwindi.

Mankhwala omwe amaletsa michere ya chiwindi ya CYP3A4 ndi CYP2D6 ndi monga erythromycin, ketoconazole, ndi ritonavir yomwe imatha kukulitsa kuchuluka kwa ma opioid mthupi ndikuwonjezera mavuto. Mankhwala omwe amachititsa kuti michere ya CYP3A4 ya chiwindi ikhale ndi carbamazepine ndi phenytoin yomwe imatha kutsitsa kuchuluka kwa ma opioid mthupi ndikuchepetsa mphamvu.

Tramadol ndi hydrocodone amathanso kulumikizana ndi mankhwala ena omwe ali ndi zovuta za CNS. Mitundu iyi ya mankhwala imaphatikizapo mankhwala opatsirana pogonana, ma anticonvulsants, benzodiazepines, zopumulira minofu, ndi zina zambiri. Kutenga ma opioid omwe ali ndi antidepressants omwe amachulukitsa serotonin kumatha kuwonjezera chiopsezo cha matenda a serotonin, vuto lalikulu lomwe limafunikira chithandizo chadzidzidzi.

Malinga ndi chizindikiro cha FDA cha mankhwala, tramadol amathanso kulumikizana ndi digoxin ndi warfarin. Malipoti apeza zochitika zosowa kwambiri za digoxin kawopsedwe ndikusintha kwa warfarin. Chizindikiro cha FDA cha hydrocodone chimanenanso kuti mankhwala ofewetsa tuvi tolimba angachepetse mphamvu ya hydrocodone mthupi.

Sikoyenera kumwa mowa mukamagwiritsa ntchito ma opioid. Mowa umatha kuwonjezera zovuta za ma opioid monga kugona ndi chizungulire.

Mankhwala osokoneza bongo	Gulu la Mankhwala	Zamgululi	Hydrocodone
Mankhwalawa Clarithromycin Telithromycin Rifampin	Maantibayotiki	Inde	Inde
Ketoconazole Chinthaka	Wothandizira antifungal	Inde	Inde
Ritonavir Atazanavir Darunavir Indinavir Lopinavir Saquinavir	Protease choletsa	Inde	Inde
Phenytoin Carbamazepine	Wosakanikirana	Inde	Inde
Kuyanjana Fluoxetine Paroxetine Sertraline Citalopram	Kusankha serotonin reuptake inhibitor (SSRI) antidepressant	Inde	Inde
Katemera Milnacipran Duloxetine Chotsani	Serotonin-norepinephrine reuptake inhibitor (SSNRI) antidepressant	Inde	Inde
Doxepin Amitriptyline Clomipramine Desipramine Imipramine Mzere wa Nortriptyline	TCA antidepressant	Inde	Inde
Naratriptan Rizatriptan Sumatriptan Zolmitriptan	Zamgululi	Inde	Inde
Alprazolam Clonazepam Diazepam MulembeFM	Benzodiazepine	Inde	Inde
Rasagiline Isocarboxazid Phenelzine Selegiline Zamgululi	Monoamine oxidase inhibitor (MAOI)	Inde	Inde
Cyclobenzaprine Metaxalone	Kutulutsa minofu	Inde	Inde
Lactulose	Mankhwala ofewetsa tuvi tolimba	Ayi	Inde
Digoxin	Mtima glycoside	Inde	Ayi
Warfarin	Wotsutsa	Inde	Ayi

* Uwu sungakhale mndandanda wathunthu wazomwe zingachitike mukamamwa mankhwala osokoneza bongo. Funsani dokotala ndi mankhwala onse omwe mukumwa.

Machenjezo a Tramadol ndi Hydrocodone

Tramadol ndi hydrocodone zimakhala ndi chenjezo lokonda kumwa mowa mwauchidakwa ngati siligwiritsidwe ntchito monga mwalamulo. Kuledzera kumatha kubweretsa kudalira thupi komwe kumatha kubweretsa zizindikiritso zakubwezeretsa ngati mankhwalawo atayimitsidwa pazifukwa zilizonse. Zizindikiro zobwerera mmbuyo zimatha kuphatikizira nkhawa, kugona tulo, komanso kusokonezeka.

Kutenga mopitilira muyeso woyenera wa ma opioid kumatha kuwonjezera ngozi ya bongo, kukomoka, ndi imfa. Zotsatira zoyika moyo pangozi monga kupsinjika kwakukulu kwa kupuma ndi kugona kungachitike ndi bongo. Pachifukwa ichi, ma opioid sakulimbikitsidwa mwa ana chifukwa cha chiwopsezo chowonjezeka cha mavuto a kupuma ndi imfa .

Sikoyenera kumwa mowa kapena kumwa mankhwala ena a CNS ndi ma opioid. Izi ndichifukwa choti zimawonjezera chiopsezo cha zotsatira za CNS monga sedation, kupuma pang'onopang'ono, kukomoka, ndi kufa. Ngakhale zambiri zimafunikira, zatsopano kufufuza akuwonetsa kuti tramadol ikhoza kukhala ndi chiopsezo chachikulu chaimfa yonse poyerekeza ndi mankhwala oletsa kutupa.

Ma tramadol ndi ma hydrocodone onse ali mgulu la amayi C. Chifukwa chake, samalimbikitsidwa makamaka azimayi omwe ali ndi pakati kapena akuyamwitsa chifukwa chowopsa kwa mwana wosabadwa. Funsani upangiri wachipatala ngati muli ndi pakati kapena mukukonzekera kukhala ndi pakati.

Mafunso omwe amafunsidwa pafupipafupi za Tramadol vs. Hydrocodone

Kodi tramadol ndi chiyani?

Tramadol ndi mankhwala opioid omwe amagwiritsidwa ntchito pochiza ululu wopweteka kwambiri. Ndi mankhwala a Ndandanda IV omwe amafunikira mankhwala ndi kuwunika kupweteka kwa dokotala. Ikupezeka pakamasulidwe kamodzi ndikutulutsa kotulutsidwa kutengera kupweteka.

Kodi hydrocodone ndi chiyani?

Hydrocodone ndi mankhwala opioid omwe amatha kupweteka kwambiri. Ndi mankhwala a Pulogalamu yachiwiri omwe atha kukhala ndi mwayi waukulu wozunza komanso kudalira. Amapezeka mufomu yotulutsidwa komanso piritsi losakaniza ndi acetaminophen.

Kodi tramadol ndi hydrocodone ndizofanana?

Ngakhale onsewa ndi ma opioid, tramadol ndi hydrocodone sizofanana. Amagwiritsanso ntchito chimodzimodzi kutengera ululu womwe mukukumana nawo. Koma amabweranso mumitundu yosiyanasiyana ndipo amakhala ndi zovuta zina komanso machitidwe amankhwala.

Kodi tramadol kapena hydrocodone ndiyabwino?

Kafukufuku akuwonetsa kuti tramadol ndi hydrocodone zonse zimathandizanso pakumva kupweteka. Malipoti ena akuwonetsa kuti tramadol ili ndi zovuta zoyipa poyerekeza ndi hydrocodone. Komabe, kafukufuku wina akuwonetsa kuti hydrocodone ndiyamphamvu kwambiri ndipo imapumitsa ululu kwa anthu ena.

Kodi tramadol ndi yamphamvu kuposa codeine?

Onse tramadol ndi codeine amatha kuchepetsa ululu ndipo onse amawoneka ngati opioid ofooka. Komabe, amatha kusiyanasiyana pazotsatira zawo ndi kagwiritsidwe kake. Mosiyana ndi tramadol, codeine itha kugwiritsidwanso ntchito ngati choletsa chifuwa.

Kodi tramadol ndi opiate?

Inde. Tramadol ndi mankhwala osokoneza bongo. Amapangidwa mwaluso ndipo ali mgulu lomwelo la mankhwala monga opioid opweteka ena. Monga mankhwala a Ndandanda IV, ili ndi mwayi wochepa wochitira nkhanza komanso kudalira poyerekeza ndi ma opioid ena.