Metoprolol tartrate vs. metoprolol succinate: Kusiyana, kufanana, ndi zomwe zili zabwino kwa inu
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Ngati mwadwalapo mtima kapena mukukhala ndi kuthamanga kwa magazi, dokotala wanu akhoza kukupatsani mankhwala ngati metoprolol tartrate (Lopressor) kapena metoprolol succinate (Toprol XL). Ngakhale mankhwala onsewa ali ndi zinthu zofananira, atha kugwiritsidwa ntchito m'njira zosiyanasiyana.
Onse metoprolol tartrate ndi metoprolol succinate ali m'gulu la mankhwala omwe amatchedwa zotchinga beta . Nthawi zina amadziwikanso kuti beta-1 osankha adrenoceptor blockers komanso otsutsana ndi beta.
Mankhwalawa amagwira ntchito poletsa zotsatira za mahomoni monga epinephrine ndi norepinephrine mu dongosolo lamanjenje lomvera. Mchitidwe wamanjenje wachifundo umayambitsa mayankho omenyera nkhondo kapena kuthawa. Metoprolol itha kuthandiza kuchepetsa kupsinjika pamtima, kumasula mitsempha yamagazi kuti ichepetse kuthamanga kwa magazi, ndikuchepetsa kupweteka pachifuwa.
Kodi pali kusiyana kotani pakati pa metoprolol tartrate ndi metoprolol succinate?
Kusiyanitsa kwakukulu pakati pa metoprolol tartrate (Metoprolol tartrate ndi chiyani?) Ndi metoprolol succinate (Kodi metoprolol succinate ndi chiyani?) Ili m'mapangidwe awo. Metoprolol tartrate ndiye mtundu wa metoprolol pomwe metoprolol succinate ndiwowonjezera womwe umatulutsidwa. Izi zikutanthauza kuti metoprolol succinate imamasulidwa pakapita nthawi m'thupi zomwe zimabweretsa zotsatira zoyipa.
Metoprolol tartrate angafunike kumwedwa kangapo patsiku. Metoprolol succinate imatha kumwedwa kamodzi tsiku lililonse chifukwa imatenga nthawi yayitali kuposa mawonekedwe amtundu wina. Metoprolol succinate itha kugwiritsidwanso ntchito kwa ana azaka 6 kapena kupitirira pomwe metoprolol tartrate itha kugwiritsidwa ntchito kwa akulu.
| Kusiyana kwakukulu pakati pa metoprolol tartrate ndi metoprolol succinate | ||
|---|---|---|
| Metoprolol Tartrate | Metoprolol Succinate | |
| Gulu la mankhwala osokoneza bongo | Beta blocker | Beta blocker |
| Chizindikiro cha Brand / generic | Ma brand ndi generic amapezeka | Ma brand ndi generic amapezeka |
| Kodi dzina lake ndi ndani? | Lopressor | Toprol XL |
| Kodi mankhwalawa amabwera mwa mawonekedwe ati? | Piritsi lapakamwa | Piritsi lapakamwa, kutulutsa kwina |
| Kodi mulingo woyenera ndi uti? | 100 mg mpaka 400 mg tsiku lililonse m'magulu osiyanasiyana | 100 mg kamodzi tsiku lililonse |
| Kodi mankhwalawa amatenga nthawi yayitali bwanji? | Kugwiritsa ntchito kwakanthawi kochepa kapena kwakanthawi kochepa monga mwadongosolo la dokotala | Kugwiritsa ntchito kwakanthawi kochepa kapena kwakanthawi kochepa monga mwadongosolo la dokotala |
| Ndani amagwiritsa ntchito mankhwalawa? | Akuluakulu | Akuluakulu ndi ana azaka 6 kapena kupitilira apo |
Mukufuna mtengo wabwino kwambiri pa metoprolol tartrate?
Lowani zidziwitso zamitengo ya metoprolol tartrate ndikupeza kuti mitengo ikasintha liti!
Pezani zidziwitso zamitengo
Zinthu zomwe zimathandizidwa ndi metoprolol tartrate ndi metoprolol succinate
Mitundu ya tartrate ndi succinate ya metoprolol ndi yovomerezeka ndi FDA yothana ndi kuthamanga kwa magazi (kuthamanga kwa magazi) komanso kupweteka pachifuwa (angina pectoris).
Metoprolol tartrate ndiyonso yovomerezeka ndi FDA ngati mankhwala atangomaliza matenda amtima (pachimake m'mnyewa wamtima infarction). Kutenga metoprolol tartrate pambuyo povutika ndi mtima kumatha kuchepetsa kuchepa kwa zochitika zina zamtima ndi kufa makamaka kwa iwo omwe ali ndi matenda amitsempha yamitsempha. Chithandizo chimayenera kuyamba mkati mwa masiku 3 mpaka 10 kudwala kwa mtima.
Kuphatikiza pa kuthamanga kwa magazi komanso kupweteka pachifuwa, metoprolol succinate imavomerezedwanso ndi FDA kuti ichiritse congestive mtima kulephera . Makamaka, metoprolol imathandizira kuthana ndi mtima kosatha komwe ndiko Bungwe la New York Heart kalasi II kapena III. Popeza kuti ndi tsiku lililonse, metoprolol succinate imatha kukonza zotsatira ndikuchepetsa chiopsezo chakufa kwa odwala olephera mtima.
Kutumiza Kugwiritsa ntchito metoprolol kumaphatikizapo supraventricular tachycardia (kugunda kwamtima mwachangu) ndi chimphepo cha chithokomiro (zoopsa zomwe zimadza chifukwa cha kuchuluka kwa mahomoni a chithokomiro) Ntchito zina zomwe sizigwiritsidwa ntchito pamtunduwu zitha kuphatikizira chithandizo chaphokoso la mtima (arrhythmia) ndi kuda nkhawa .
| Mkhalidwe | Metoprolol Tartrate | Metoprolol Succinate |
| Kuthamanga kwa magazi | Inde | Inde |
| Matenda opweteka pachifuwa | Inde | Inde |
| Pachimake mtima | Inde | Kutumiza |
| Mtima kulephera | Kutumiza | Inde |
| Supraventricular tachycardia | Kutumiza | Kutumiza |
| Mphepo yamkuntho | Kutumiza | Kutumiza |
| Mpweya | Kutumiza | Kutumiza |
| Kuda nkhawa | Kutumiza | Kutumiza |
Kodi metoprolol tartrate kapena metoprolol imathandizira kwambiri?
Metoprolol tartrate ndi metoprolol succinate zonse zimakhala zofananira pochiza kuthamanga kwa magazi komanso kupweteka pachifuwa. Komabe, metoprolol tartrate itha kukhala yothandiza kwambiri pochiza matenda amtima pomwe metoprolol succinate imatha kukhala yothandiza kwambiri pochiza kulephera kwamtima.
Zachipatala mayesero awonetsa kuti metoprolol tartrate imathandizira kuthamanga kwa magazi komanso kupewa zotsatira zoyipa pambuyo povutika ndi mtima. M'malo mwake, maphunziro kuphatikiza kuyesedwa kwa Merit-HF asonyeza kuti metoprolol succinate ndiyabwino kuposa metoprolol tartrate yolephera mtima mtima.
Metoprolol succinate imatha kuchepa kubwereranso kuchipatala ndikumwalira chifukwa cha mtima. Komabe, chosema , beta blocker yodziwika bwino, itha kukhala yothandiza kwambiri kuposa metoprolol succinate, malinga ndi kuyeserera kofalitsidwa mu Lancet .
Chifukwa metoprolol tartrate amatengedwa kangapo tsiku lonse, kuchuluka kwa mankhwala m'thupi sikungafanane. Izi zitha kubweretsa zovuta zina komanso kulekerera pang'ono poyerekeza ndi mawonekedwe a succinate owonjezera. Chimodzi kusanthula anapeza kuti zotsatira zoyipa monga kugunda kwamtima pang'ono (bradycardia) zitha kuchitika ndikutulutsa metoprolol tartrate posachedwa.
Kuphatikiza ndi kuyerekezera mtengo wa metoprolol tartrate vs. metoprolol succinate
Metoprolol tartrate itha kugulidwa ngati mankhwala ochiritsira omwe nthawi zambiri amapangidwa ndi Medicare ndi mapulani ena a inshuwaransi. Popanda inshuwaransi, pafupifupi mtengo wamtengo wa generic metoprolol tartrate pafupifupi $ 5. Makhadi ochotsera a SingleCare atha kugwiritsidwa ntchito kuma pharmacies omwe akutenga nawo mbali kuti muchepetse mtengo wa mankhwalawa. Mutha kupeza mtengo pafupi ndi $ 4 ndi coupon yosungira.
Metoprolol succinate kapena metoprolol yotulutsa nthawi yayitali imapezeka ngati mankhwala achibadwa omwe amapezeka ndi Medicare ambiri ndi mapulani a inshuwaransi. Mankhwala otchedwa generic metoprolol succinate amatha kuphimbidwa kuposa dzina la Toprol XL. Mtengo wapakatikati wa Toprol XL ndi pafupifupi $ 56. Funsani ku pharmacy yanu kuti muwone ngati mungasunge zambiri ndi khadi yosungira ya SingleCare. Ngati zivomerezedwa, mutha kuchepetsa mtengo kukhala $ 9.
| Metoprolol Tartrate | Metoprolol Succinate | |
| Nthawi zambiri amakhala ndi inshuwaransi? | Inde | Inde |
| Nthawi zambiri amakhala ndi Medicare? | Inde | Inde |
| Mlingo woyenera | Mapiritsi 50 mg | Mapiritsi 100 mg |
| Wopanga Medicare wamba | $ 0- $ 65 | $ 0- $ 20 |
| Mtengo wosakwatiwa | $ 4 | $ 9 |
Pezani khadi yochotsera mankhwala
Zotsatira zoyipa za metoprolol tartrate vs. metoprolol succinate
Metoprolol tartrate ndi metoprolol succinate zimatha kuyambitsa zovuta zina. Zotsatira zoyipa kwambiri za metoprolol zimaphatikizapo kutopa kapena kutopa, chizungulire, kukhumudwa, kupuma movutikira (dyspnea), komanso kugunda kwamtima pang'ono (bradycardia). Zotsatira zina zimaphatikizapo kutsegula m'mimba, nseru, kusanza, ndi pakamwa pouma.
Hypersensitivity reaction monga zotupa kapena kuyabwa zitha kuchitikanso mukatenga mtundu uliwonse wa metoprolol. Kutengera Chizindikiro cha FDA , metoprolol tartrate imatha kukhala ndi zovuta zina.
| Metoprolol Tartrate | Metoprolol Succinate | |||
| Zotsatira zoyipa | Zoyenera? | Pafupipafupi | Zoyenera? | Pafupipafupi |
| Kutopa | Inde | 10% | Inde | > 2% |
| Chizungulire | Inde | 10% | Inde | > 2% |
| Kutupa | Inde | 5% | Inde | > 2% |
| Matenda okhumudwa | Inde | 5% | Inde | > 2% |
| Kutsekula m'mimba | Inde | 5% | Inde | > 2% |
| Kupuma pang'ono | Inde | 3% | Inde | > 2% |
| Kugunda kwa mtima pang'ono | Inde | 3% | Inde | > 2% |
| Pakamwa pouma | Inde | 1% | Inde | * sananene |
| Nseru | Inde | 1% | Inde | * |
| Kutentha pa chifuwa | Inde | 1% | Inde | * |
| Kudzimbidwa | Inde | 1% | Inde | * |
Uwu sungakhale mndandanda wathunthu. Funsani dokotala wanu kapena wamankhwala pazotsatira zomwe zingachitike.
Gwero DailyMed (metoprolol tartrate) , DailyMed (metoprolol succinate)
Kuyanjana kwa mankhwala a metoprolol tartrate vs. metoprolol succinate
Metoprolol tartrate ndi metoprolol succinate amatha kulumikizana ndi mankhwala omwewo. Mankhwala ena omwe amachitanso chimodzimodzi kapena amakhudza kagayidwe kake ka beta blockers amatha kulumikizana ndi mitundu yonse ya metoprolol.
Metoprolol sayenera kutengedwa ndi mankhwala osokoneza bongo a catecholamine. Kutenga mankhwalawa palimodzi kumatha kukulitsa zovuta za beta blockers ndikupangitsa zovuta monga kuthamanga kwa magazi ( hypotension ) ndikuchedwa kugunda kwa mtima (bradycardia). Zotsatira zina zoyipa zimatha kukhala ndi chizungulire komanso kukomoka.
Metoprolol imagwiritsidwa ntchito kwambiri ndi puloteni ya CYP2D6. Chifukwa chake, mankhwala omwe amaletsa enzyme iyi amatha kuyambitsa kuchuluka kwa metoprolol mthupi. Kuchulukitsa kwa metoprolol kumatha kuwonjezera ngozi zoyipa.
Digoxin ndi mankhwala omwe amatchedwa calcium channel blockers atha kukhala ndi zowonjezera pamene amaperekedwa ndi metoprolol. Kutenga iliyonse ya mankhwalawa ndi metoprolol kumatha kuyambitsa mavuto mumtima.
| Mankhwala osokoneza bongo | Gulu la Mankhwala | Metoprolol Tartrate | Metoprolol Succinate |
| Onaninso Tetrabenazine | Mankhwala osokoneza bongo a Catecholamine | Inde | Inde |
| Quinidine Fluoxetine Fluvoxamine Sertraline Bupropion Paroxetine Zamgululi Haloperidol Diphenhydramine Hydroxychloroquine Terbinafine | CYP2D6 choletsa | Inde | Inde |
| Digoxin | Mtima glycoside | Inde | Inde |
| Diltiazem Kutumiza | Njira yoletsa calcium | Inde | Inde |
| Clonidine Guanethidine Betanidine | Alpha-adrenergic wothandizira | Inde | Inde |
Izi sizingakhale mndandanda wathunthu wazomwe zingachitike mukamagwiritsa ntchito mankhwala osokoneza bongo. Funsani dokotala ndi mankhwala onse omwe mukumwa.
Machenjezo a metoprolol tartrate ndi metoprolol succinate
Onse metoprolol tartrate ndi metoprolol succinate sayenera kutha mwadzidzidzi. Ngati mankhwala a metoprolol atayimitsidwa mwadzidzidzi, anthu ena atha kukhala pachiwopsezo chachikulu chodwala matenda amtima, zachilendo mungoli wamtima , ndi kupweteka pachifuwa. Kuopsa kwa zochitikazi ndikokulira kwa omwe ali ndi matenda amtima.
Ma Beta blockers ngati metoprolol sayenera kugwiritsidwa ntchito kwa aliyense amene ali ndi izi:
- Kwambiri bradycardia
- Mtima wolimba kuposa digiri yoyamba
- Kusokonezeka kwamtima
- Kutha mtima kwa mtima
- Matenda a sinus osadwala opanda pacemaker
- Hypersensitivity pazosakaniza zilizonse za mankhwalawa
Funsani dokotala kuti muwone ngati mungakhale ndi zina mwazimenezi musanayambe chithandizo.
Beta blockers amatha kubisa zizindikilo za hypoglycemia, kapena shuga wotsika magazi. Omwe ali ndi matenda ashuga angafunikire kuwunika shuga wawo wamagazi akamamwa ma beta blockers.
Mafunso omwe amafunsidwa pafupipafupi okhudza metoprolol tartrate vs. metoprolol succinate
Kodi metoprolol tartrate ndi chiyani?
Metoprolol tartrate ndi dzina lodziwika bwino la Lopressor. Ndi beta blocker yomwe imagwiritsidwa ntchito pochiza kuthamanga kwa magazi komanso kupweteka pachifuwa. Ikuvomerezedwanso kuti athandizidwe ndimatenda amtima kuti athetse ngozi zakufa.
Kodi metoprolol succinate ndi chiyani?
Metoprolol succinate imadziwikanso ndi dzina loti Toprol XL. Ndi njira yotulutsira metoprolol. Metoprolol succinate imavomerezedwa kuchiza kuthamanga kwa magazi, kupweteka pachifuwa, komanso kupindika kulephera kwa mtima .
Kodi metoprolol tartrate ndi metoprolol zimathandizira chimodzimodzi?
Ayi. Metoprolol tartrate ndi piritsi lotulutsa pomwepo pomwe metoprolol succinate ndi pulogalamu yotulutsa nthawi yayitali. Zitha kugwiritsidwa ntchito m'njira zosiyanasiyana.
Kodi metoprolol tartrate kapena metoprolol imathandizira bwino?
Metoprolol tartrate ndi metoprolol succinate zonse ndizothandiza kutengera momwe akuchiritsira. Metoprolol succinate ndiyothandiza kwambiri pochiza kulephera kwa mtima. Metoprolol succinate amathanso kubweretsa zovuta zina.
Kodi ndingagwiritse ntchito metoprolol tartrate kapena metoprolol succinate ndili ndi pakati?
Metoprolol iyenera kugwiritsidwa ntchito panthawi yapakati ngati maubwino ake akupitilira zoopsa zake. Palibe maphunziro okwanira omwe adachitika posonyeza kuti mankhwalawa ndi otetezeka 100% panthawi yapakati. Funsani dokotala ngati muli ndi pakati kapena mukuyamwitsa.
Kodi ndingagwiritse ntchito metoprolol tartrate kapena metoprolol succinate ndi mowa?
Kumwa mowa ndikumwa mankhwala a metoprolol kumawonjezera chiopsezo cha kugona ndi chizungulire. Sikulimbikitsidwa kuti mugwiritse ntchito metoprolol ndi mowa .
Kodi mungasinthe kuchokera ku metoprolol tartrate kupita ku succinate?
Nthawi zina, metoprolol tartrate imatha kusintha metoprolol succinate. Metoprolol succinate itha kusankhidwa chifukwa chotsatira kamodzi patsiku. Funsani dokotala kuti adziwe zomwe mungachite mukamasintha mankhwala.
Kodi simukuyenera kumwa metoprolol liti?
Metoprolol sayenera kutengedwa ngati mukumva kutsika kwambiri kwa mtima, kuthamanga kwa magazi, kapena kulephera kwamtima. Ndikofunikira kukambirana mbiri yanu yazachipatala ndi dokotala kuti mudziwe ngati muyenera kukhala pa metoprolol.
Kodi ndiyenera kupewa chiyani ndikumwa metoprolol?
Mowa ndi mankhwala ena ayenera kupewedwa mukamamwa metoprolol. Mankhwala ena kuphatikiza calcium blockers, ena mankhwala opatsirana pogonana , Ndipo omwe amasinthidwa mofananamo ndi metoprolol atha kuwonjezera ngozi zoyipa ndi metoprolol.
Kodi metoprolol ndi mankhwala owopsa?
Inde. Metoprolol ikhoza kuonedwa ngati mankhwala oopsa. Pogwiritsidwa ntchito molakwika, metoprolol imatha kuvulaza kwambiri.
