Waukulu >> Mankhwala Osokoneza Bongo Vs. Mnzanu >> Methylprednisolone vs. prednisone: Kusiyana, kufanana, ndi zomwe zili bwino

Methylprednisolone vs. prednisone: Kusiyana, kufanana, ndi zomwe zili bwino

Mankhwala osokoneza bongo Vs. Mnzanu

Methylprednisolone ndi prednisone ndizopanga ma glucocorticoids omwe amagwiritsidwa ntchito pamavuto osiyanasiyana. Mankhwalawa ndi ofanana kwambiri ndi mahomoni omwe amapangidwa ndi thupi lanu la adrenal gland. Mukapatsidwa mankhwala okwera kwambiri kuposa momwe thupi lanu limapangidwira lokha, imagwira ntchito m'njira zosiyanasiyana zoletsa zida zina zoteteza mthupi komanso zotupa monga leukotrienes, prostaglandins, kinins, ndi histamines. Njira imeneyi imathandizira kuti mankhwalawa azitha kuchiza matenda am'mapapo, zovuta zama autoimmune, ndi zovuta zotupa, kungotchulapo ochepa. Ngakhale mankhwala onsewa atha kugwiritsidwa ntchito pamavuto omwewo, pali kusiyana pakati pa awiriwa.

Kodi pali kusiyana kotani pakati pa methylprednisolone ndi prednisone?

Methylprednisolone ndi mankhwala akuchipatala omwe amagwiritsidwa ntchito pamavuto osiyanasiyana kuphatikizapo mphumu, ulcerative colitis, nyamakazi ya nyamakazi, komanso kusokonezeka. Methylprednisolone ndichotengera cha prednisolone, ndipo momwe amagwirira ntchito zimapangitsa kuti ikhale yothandiza pamatenda osiyanasiyana otupa komanso chitetezo chamthupi. Methylprednisolone imadutsa ma membrane am'manja ndipo imamangiriza kuzomvera zomwe zimalepheretsa kaphatikizidwe ka mapuloteni ndikupanga ma cytokines. Ma Cytokines amatenga gawo lofunikira pakuwotcha. Mwa njira yomweyi, imayimitsanso kulowetsedwa kwa ma leukotrienes ndi zina zomwe zimayankha chitetezo cha mthupi. Izi zimapangitsa kuti mankhwalawa azigwira ntchito ngati anti-inflammatory and immunosuppressive agent.

Methylprednisolone imapezeka mu 4 mg, 8 mg, 16 mg, ndi 32 mg mapiritsi amlomo. Ikupezekanso mu mayankho omwe angaperekedwe ngati jakisoni wamitsempha kapena wamitsempha. Mapiritsi a methylprednisolone ndi Medrol. Methylprednisolone itha kugwiritsidwa ntchito kwa makanda, ana, komanso akulu.

Prednisone ndi mankhwala akuchipatala omwe amagwiritsidwanso ntchito m'matenda osiyanasiyana am'mimba komanso chitetezo chamthupi. Prednisone ndi chochokera ku cortisone ndipo imayenera kupukusidwa ndi chiwindi mu mawonekedwe ake, prednisolone, kuti iwoloke nembanemba yama cell. Ikadutsa nembanemba, makina ake amafanana ndi methylprednisolone chifukwa imalepheretsa kulowererapo kwa zotupa komanso zoteteza kumatenda.

Prednisone amathanso kutchedwa dzina lake Deltasone. Amapezeka mu 2.5 mg, 5 mg, 10 mg, 20 mg, ndi 50 mg mapiritsi amlomo. Ikupezekanso poyankha pakamwa.

Kusiyana kwakukulu pakati pa methylprednisolone vs. prednisone
	Methylprednisolone	Prednisone
Gulu la mankhwala osokoneza bongo	Corticosteroid	Corticosteroid
Chizindikiro cha Brand / generic	Zolemba ndi generic zilipo	Zolemba ndi generic zilipo
Kodi dzina lake ndi ndani?	Medrol, SoluMedrol	Deltasone
Kodi mankhwalawa amabwera mwa mawonekedwe ati?	Piritsi lapakamwa, Njira yothetsera jakisoni	Piritsi lapakamwa, yankho lakamwa
Kodi mulingo woyenera ndi uti?	Mlingo woyambirira wa 4 mg mpaka 48 mg wokhala ndi titation potengera kuyankha ndi kuzindikira	Mlingo woyambirira wa 5 mg mpaka 60 mg ndikulemba potengera mayankho ndi kuzindikira
Kodi mankhwalawa amatenga nthawi yayitali bwanji?	Masiku asanu ndi limodzi mpaka milungu ingapo kapena kupitilira kutengera matenda.	Masiku asanu mpaka milungu ingapo kapena kupitilira kutengera matenda.
Ndani amagwiritsa ntchito mankhwalawa?	Makanda, ana, ndi akulu	Makanda, ana, ndi akulu

Mukufuna mtengo wabwino pa prednisone?

Lowani zidziwitso zamitengo ya prednisone ndikupeza kuti mitengo ikasintha liti!

Pezani zidziwitso zamitengo

Zomwe zimathandizidwa ndi methylprednisolone vs. prednisone

Methylprednisolone imagwiritsidwa ntchito pochiza matenda osiyanasiyana ndi zovuta. Zotsatira zake pamatenda amtunduwu zimapangitsa kuti zithandizire pamavuto am'mimba monga rheumatoid ndi psoriatic nyamakazi, spondylitis, ndi bursitis. Amagwiritsidwanso ntchito pochiza matenda oyipa a mphumu. Mankhwala a methylprednisolone amachititsa kuti azitha kuchiza matendawa monga matenda a rhinitis, kukhudzana ndi dermatitis, komanso kukhudzidwa kwa mankhwala. Amagwiritsidwanso ntchito mu endocrine, collagen, hematologic, m'mimba, ndi matenda amaso.

Prednisone imagwiritsidwanso ntchito kuthana ndi zovuta zambiri zotupa komanso zoteteza thupi zomwe zimafanana ndi methylprednisolone. Izi zikuphatikizapo rheumatic, kupuma, matupi awo sagwirizana, endocrine, collagen, hematologic, m'mimba, ndi ophthalmic.

Gome lotsatirali, ngakhale likukulira, silingalembetse kugwiritsa ntchito mankhwala awiriwa. Chonde funsani omwe akukuthandizani kuti mumve zambiri za momwe mungagwiritsire ntchito.

Mkhalidwe	Methylprednisolone	Prednisone
Kobadwa nako adrenal hyperplasia	Inde	Inde
Nonsuppurative thyroiditis	Inde	Inde
Matenda a nyamakazi	Inde	Inde
Ankylosing spondylitis	Inde	Inde
Pachimake bursitis	Inde	Inde
Synovitis ya nyamakazi	Inde	Inde
Matenda a Psoriatic	Inde	Inde
Zokhudza lupus erythematosus	Inde	Inde
Matenda owopsa a seborrheic	Inde	Inde
Kwambiri psoriasis	Inde	Inde
Chamawonedwe neuritis	Inde	Inde
Matupi conjunctivitis	Inde	Inde
Chizindikiro sarcoidosis	Inde	Inde
Kutulutsa pneumonitis	Inde	Inde
Idiopathic thrombocytopenic purpura	Inde	Inde
Zilonda zam'mimba	Inde	Inde
Kuwonjezeka koopsa kwa Multiple Sclerosis	Inde	Inde

Kodi methylprednisolone kapena prednisone ndiyothandiza kwambiri?

Pali njira zambiri zoyerekeza methylprednisolone ndi prednisone chifukwa chogwiritsa ntchito kwambiri. Mu njira zambiri zotupa, chithandizo cha corticosteroids chimangogwiritsidwa ntchito kwakanthawi kochepa pakuwonjezera kwakukulu kwa matendawa. Poyerekeza methylprednisolone ndi prednisone mwachindunji, 4 mg ya methylprednisolone ndiyofanana ndi 5 mg ya prednisone. Komabe, pamene mankhwala asinthidwa ndikuyang'aniridwa kuti ayankhe, aliyense atha kukhala othandiza.

Kafukufuku wina adayesa kuyerekezera zotsatira za methylprednisolone yolowa mkati kuti prednisone pakamwa mukulira koopsa kwa mphumu mwa ana. Magulu awiri azachipatala adasinthidwa mwachisawawa kuti alandire 30 mg ya methylprednisolone kapena 30 mg ya oral prednisone. Magulu onse awiriwa adalandira albuterol, ndipo ofufuza adasanthula kupumula kwamatenda, kuthamanga kwapamwamba (PEF), komanso kuwerengera kwa oximetry. Kuwerengedwa kunatengedwa pagulu lililonse patadutsa maola awiri, anayi, ndi maora sikisi atayamba kulandira chithandizo. Panalibe kusiyana kwakanema kapena kochulukirapo pakadutsa kalikonse pakati pa magulu awiriwa. Ofufuzawo adazindikira kuti prednisone yakumlomo ndi yomwe ingakhale chisankho chabwino chifukwa chotsika mtengo komanso kuwongolera kovuta.

Mukufuna mtengo wabwino kwambiri pa methylprednisolone?

Lowani zidziwitso zamitengo ya methylprednisolone ndikupeza kuti mitengo ikasintha liti!

Pezani zidziwitso zamitengo

Kuphunzira ndi kuyerekezera mtengo wa methylprednisolone vs. prednisone

Methylprednisolone ndi mankhwala akuchipatala omwe amapezeka ndi mapulani onse a inshuwaransi komanso Medicare. Njira yamasiku asanu ndi limodzi yamapiritsi 21 a mphamvu ya 4 mg itha kukhala ngati $ 100 ya dzina lake. Ndi coupon yochokera ku SingleCare, mutha kupeza methylprednisolone yotsika $ 15.

Prednisone ndi mankhwala akuchipatala omwe amakhala ndi mapulani a inshuwaransi yamalonda komanso Medicare. Mtengo wapakatikati wa prednisone ndi pafupifupi $ 22 pamapiritsi khumi a 20 mg. Mutha kupeza mankhwalawa pansi pa $ 4 ndi coupon ya SingleCare.

Ndikofunika kudziwa kuti kumatenda ena, ma corticosteroids sangatetezedwe ndi mankhwala, koma atha kupezeka ndi Medicare Part B. Katswiri wanu wamafuta atha kukupatsirani zambiri pakufalitsa.

	Methylprednisolone	Prednisone
Nthawi zambiri amakhala ndi inshuwaransi?	Inde	Inde
Nthawi zambiri amakhala ndi Medicare?	Inde	Inde
Mlingo woyenera	21, 4 mg mapiritsi	10, 20 mg mapiritsi
Wopanga Medicare wamba	Nthawi zambiri<$10 but may vary depending on the plan	Nthawi zambiri<$10 but may vary depending on the plan
Mtengo wosakwatiwa	$ 15 +	$ 4- $ 6

Zotsatira zoyipa za methylprednisolone ndi prednisone

Prednisone imagwiritsidwa ntchito ndi metabolite prednisolone ndi chiwindi. Prednisolone ndi methylprednisolone ndizofanana kwambiri, motero zotsatira zake zoyipa zimayenderana.

Glucocorticoids amadziwika kuti amayambitsa kusamvana kwamadzimadzi ndi ma electrolyte komwe kumatha kubweretsa kusungika kwa sodium ndi madzimadzi, kuthamanga kwa magazi, ndipo nthawi zina, kulephera kwa mtima. Methylprednisolone ndi prednisone amathanso kubweretsa kufooka kwa minofu ndikuchepa kwa minofu. Glucocorticoids amadziwika kuti akusokoneza m'mimba ndipo amatha kuyambitsa nseru, kusanza, kapena kuphulika m'mimba. Steroids imatha kuchepetsa kuchira kwa mabala. Kugwiritsa ntchito methylprednisolone ndi prednisone kwa nthawi yayitali kumachedwetsa kukula kwa ana, ndipo pachifukwa ichi, kugwiritsa ntchito kwawo kuyenera kuchepetsedwa kwakanthawi kochepa kuti akwaniritse kukhululukidwa kwa zizindikilo.

Glucocorticoids imatha kusokoneza kuyankha kwa thupi ku insulin. Odwala omwe amalandira mankhwalawa kwa nthawi yayitali amatha kukhala ndi mwayi wokudwala matenda ashuga kuwirikiza kanayi. Odwala omwe amadalira jakisoni wa jakisoni kapena mankhwala ena opatsirana ndi matenda a shuga amayenera kuwonjezera mlingo wawo akakhala pa steroids. Si zachilendo kwa odwala matenda ashuga omwe amawona kukwera kwa shuga m'magazi awo ngakhale pamlingo wochepa kwambiri wa steroids.

Tebulo lotsatirali siliyenera kukhala mndandanda wazotsatira zake. Chonde funsani wamankhwala kapena dokotala wanu kuti mupeze mndandanda wathunthu wazovuta zonse.

	Methylprednisolone	Prednisone
Kusungidwa kwa sodium	Zoyenera?	Pafupipafupi	Zoyenera?	Pafupipafupi
Kusungidwa kwamadzimadzi	Inde	Osatanthauziridwa	Inde	Osatanthauziridwa
Matenda oopsa	Inde	Osatanthauziridwa	Inde	Osatanthauziridwa
Kulephera kwa mtima	Inde	Osatanthauziridwa	Inde	Osatanthauziridwa
Kulemera	Inde	Osatanthauziridwa	Inde	Osatanthauziridwa
Minofu kufooka	Inde	Osatanthauziridwa	Inde	Osatanthauziridwa
Kufooka kwa mafupa	Inde	Osatanthauziridwa	Inde	Osatanthauziridwa
Kutyoka mafupa ataliatali	Inde	Osatanthauziridwa	Inde	Osatanthauziridwa
Chilonda chachikulu	Inde	Osatanthauziridwa	Inde	Osatanthauziridwa
Pancreatitis	Inde	Osatanthauziridwa	Inde	Osatanthauziridwa
Kutalika kwa m'mimba	Inde	Osatanthauziridwa	Inde	Osatanthauziridwa
Wosokonekera bala bala	Inde	Osatanthauziridwa	Inde	Osatanthauziridwa
Nkhope erythema	Inde	Osatanthauziridwa	Inde	Osatanthauziridwa
Kuchuluka thukuta	Inde	Osatanthauziridwa	Inde	Osatanthauziridwa
Mutu	Inde	Osatanthauziridwa	Inde	Osatanthauziridwa
Vertigo	Inde	Osatanthauziridwa	Inde	Osatanthauziridwa
Khalidwe limasintha	Inde	Osatanthauziridwa	Inde	Osatanthauziridwa
Kupondereza kukula	Inde	Osatanthauziridwa	Inde	Osatanthauziridwa
Kukaniza kwa insulin	Inde	Osatanthauziridwa	Inde	Osatanthauziridwa
Glaucoma	Inde	Osatanthauziridwa	Inde	Osatanthauziridwa

Gwero Methylprednisolone (Tsiku Lililonse) Prednisone (Tsiku Lililonse)

Kuyanjana kwa mankhwala a methylprednisolone ndi prednisone

Methylprednisolone ndi prednisone ndi gawo lililonse la cytochrome P450 enzyme 3A4. Njira ya enzyme ya P450 m'chiwindi imayambitsa kagayidwe ka mankhwala ambiri, chifukwa chake pali kuthekera kogwirizana ndimankhwala ambiri.

Corticosteroids amagwiritsidwa ntchito kwambiri kwa odwala omwe amakhalanso ndi othandizira ena a immunosuppressant. Kulamulira momwe thupi limayankhira pakuika ziwalo ndi zovuta zina za autoimmune zitha kufunikira kugwiritsa ntchito wopitilira muyeso wothandizira. Wothandizira wina akhoza kukhudza kagayidwe ka wina, koma atha kugwiritsidwabe ntchito ngati atayang'aniridwa moyenera. Mwachitsanzo, tacrolimus ndi cyclosporine ndi omwe amaletsa CYP 3A4. Izi zitha kubweretsa kuchuluka kwa seramu ya methylprednisolone kapena prednisone ikagwiritsidwa ntchito limodzi. Pakhala pali zovuta zam'magazi zomwe zimagwiritsidwa ntchito nthawi imodzi ya cyclosporine ndi methylprednisolone, ngakhale izi ndizosowa.

Odzetsa okodzetsa amathandizira kusungunula mawonekedwe amadzimadzi mthupi mwa kusefa potaziyamu. Mukaperekedwa ndi methylprednisolone kapena prednisone, komabe, pali kuthekera kwakuti thupi lingataye potaziyamu wambiri. Izi zitha kukhala ndi zotsatira zoyipa pamtima. Odwala omwe akuyenera kutenga izi limodzi ayenera kuyang'anitsitsa mawonekedwe awo a electrolyte.

Tebulo lotsatirali si mndandanda wazovuta zonse zomwe zingachitike. Chonde funsani omwe akukuthandizani kuti mupeze mndandanda wathunthu.

Mankhwala osokoneza bongo	Gulu la Mankhwala	Methylprednisolone	Prednisone
Zamgululi Dabrafenib Erdafitinib Ivosidenib Larotrectinib Tofacitinib Upadacitinib	Signal transduction inhibitors (STI): Ma Immunosuppressants	Inde	Inde
Denosumab Natalizumab Nivolumab Ocrelizumab Sarilumab Siltuximab	Immunoglobulins: Ma Immunosuppressants	Inde	Inde
Tacrolimus	Calcineurin inhibitor: Immunosuppressant	Inde	Inde
Cyclosporine	Kuzungulira peptide: Immunosuppressant	Inde	Inde
Wopatsa chidwi Zosintha	Wotsutsa wa NK1: Wotsutsa-kunyoza	Inde	Inde
Ketoconazole Chinthaka	Azole antifungals	Inde	Inde
Kuchotsetsa	Vasopressin analogi	Inde	Inde
Diltiazem	Njira yoletsa calcium	Inde	Inde
Isoniazid Rifampin	Antitubercular	Inde	Inde
Phenytoin	Wosakanikirana	Inde	Inde
Bumetanide Furosemide Torsemide	Zojambula za Loop	Inde	Inde
Asipilini Zamgululi Naproxen Diclofenac Meloxicam Alireza	NSAIDs	Inde	Inde
Chlorthalidone Hydrochlorothiazide	Odzetsa okodzetsa	Inde	Inde

Machenjezo a methylprednisolone ndi prednisone

Corticosteroids imatha kubisa zizindikiro za matenda ndipo imachedwetsa kupezeka kwa matenda atsopano. Kugwiritsa ntchito methylprednisolone ndi prednisone kwa nthawi yayitali kumatha kuyambitsa matenda amaso ndi khungu.

Sipanakhale maphunziro oyendetsedwa bwino a corticosteroids mwa amayi apakati, chifukwa chake kugwiritsa ntchito kwawo pobereka kumayenera kuchitika pokhapokha zikawonekeratu kuti phindu limaposa zoopsa zilizonse. Makanda obadwa kwa amayi omwe amagwiritsa ntchito corticosteroids panthawi yoyembekezera ayenera kuwonedwa chifukwa cha hypoadrenalism.

Corticosteroids, makamaka pamlingo waukulu, idzalepheretsa thupi kutulutsa ma antibodies katemera akaperekedwa. Katemera sangakhale othandiza kwa odwala omwe amalandira ma steroids. Katemera wamoyo, monga nthomba, sayenera kuperekedwa kwa odwala omwe amalandira chithandizo cha corticosteroid. Odwala omwe amatenga ma immunosuppressive agents ali pachiwopsezo chachikulu chotenga matenda kuchokera ku katemera wamoyo.

Methylprednisolone ndi prednisone zitha kusintha zotsatira zoyesedwa pakhungu kapena zina zoyeserera. Pazotsatira zolondola kwambiri, mankhwala a steroid amayenera kuyimitsidwa kutatsala masiku ochepa kuti ayesedwe.

Steroids imayenera kuperekedwa kwaufupi momwe mungathere kukwaniritsa zomwe mukufuna. Ngati kugwiritsa ntchito mankhwala otalikitsa kwa nthawi yayitali ndikofunikira kuchipatala, akuyenera kusungidwa pamlingo wochepa kwambiri.

Mafunso omwe amafunsidwa pafupipafupi za methylprednisolone vs. prednisone

Kodi methylprednisolone ndi chiyani?

Methylprednisolone ndi yopangidwa ndi glucocorticoid yomwe imagwiritsidwa ntchito kuthana ndi zovuta zosiyanasiyana zotupa ndi autoimmune. Imapezeka ngati piritsi lokamwa komanso ngati jakisoni. Chithandizo chofala kwambiri ndi masiku asanu ndi limodzi amamwa.

Kodi prednisone ndi chiyani?

Prednisone ndi glucocorticoid yomwe imasakanizidwa ndi chiwindi mmaonekedwe ake, prednisolone. Amagwiritsidwanso ntchito m'matenda ambiri otupa komanso oteteza thupi. Prednisone imapezeka m'mapiritsi amlomo ndi m'mayankho am'kamwa. Kugwiritsa ntchito kwambiri prednisone nthawi zambiri kumakhala masiku asanu.

Kodi methylprednisolone ndi prednisone ndizofanana?

Ngakhale onsewa ndi glucocorticoids, methylprednisolone ndi prednisone sizofanana ndendende. Prednisone iyenera kupangika ndi thupi momwe imagwirira ntchito, prednisolone, kuti ikhudze thupi. Mlingo wa 4 mg wa methylprednisolone ndi wofanana ndi 5 mg prednisone.

Kodi methylprednisolone kapena prednisone ndiyabwino?

Methylprednisolone ndi prednisone aliyense amatha kukwaniritsa kuchotsera chizindikiritso pamene mankhwala ake ayambitsidwa moyenera. Zokakamira pakamwa zitha kusankhidwa kuposa njira zopangira jakisoni chifukwa chotsika mtengo komanso kusamalira kosavuta.

Kodi nditha kugwiritsa ntchito methylprednisolone kapena prednisone ndili ndi pakati?

Methylprednisolone ndi prednisone ndi omwe ali pachiwopsezo chotenga mimba C. Izi zikutanthauza kuti palibe maphunziro owongoleredwa omwe akuwonetsa kuti mankhwalawa ndiabwino pathupi. Mankhwalawa ayenera kugwiritsidwa ntchito pokhapokha phindu likapambana chiwopsezo.

Kodi ndingagwiritse ntchito methylprednisolone kapena prednisone ndi mowa?

Mowa umasakanizidwa ndi chiwindi. Kumwa mowa mopitirira muyeso kungakhudze thupi kutulutsa prednisone mu mawonekedwe ake. Mowa ndi glucocorticoids zitha kukhala ndi zotsatirapo zoyipa m'matumbo. Kumwa mowa kumachepetsedwa bwino panthawi yamankhwala a steroid.

Kodi methylprednisolone ndi steroid yamphamvu?

Ngakhale methylprednisolone ndi pafupifupi 20% yamphamvu kuposa prednisone, ndi gawo limodzi mwa magawo asanu okha mwa mphamvu zina za glucocorticoids monga dexamethasone kapena betamethasone. Komabe, ndi yamphamvu kasanu kuposa hydrocortisone.

Zimatenga nthawi yayitali bwanji kuti igwiritse ntchito methylprednisolone? / Kodi methylprednisolone ikuchita mwachangu?

Methylprednisolone imayamba mwachangu. Imafika pachimake pakadutsa ola limodzi kapena awiri mutamwa, ndipo mkati mwa ola limodzi lokhala ndi intravenous dose. Imapukusidwa ndi chiwindi kukhala ma metabolites osagwira ntchito omwe amatuluka mkodzo. Hafu ya moyo wa methylprednisolone ndi 18 mpaka maola 36 zomwe zikutanthauza kuti zingatenge masiku 2 mpaka 7 kuti athetse mankhwalawa mthupi lonse.