Kodi muyenera kutenga Topamax pa migraines yanu?

Zambiri Zamankhwala

Monga kuti kukhala ndi mutu waching'alang'ala mobwerezabwereza sikumapweteka mokwanira, kuzindikira kuti ndi mankhwala ati kapena kuphatikiza kwa mankhwala omwe angakhale oyenera kwa inu kukhala vuto lalikulu. Mwamwayi, pali njira zingapo zochiritsira zomwe zingapewe komanso kuchepetsa ululu. Umenewu ndi uthenga wabwino kwa Achimereka 38 miliyoni omwe amakhala ndi mutu waching'alang'ala.

Chimodzi mwazomwe mungasankhe, Topamax ( topiramate ), amadziwika kwambiri ngati njira yodzitetezera ya migraine, ngakhale idagwiritsidwa ntchito ngati mankhwala oletsa antiepileptic kwa anthu omwe ali ndi mbiri yakugwa.

M'malo mwake, topiramate ndiye mankhwala omwe amalembedwa pakamwa kuti ateteze mutu waching'alang'ala ku United States-popeza wavomerezedwa ndi akulu akulu mu 2004, malinga ndi Deborah I. Friedman , MD, pulofesa wa zamitsempha ku University of Texas Southwestern Medical Center komanso membala wa American Headache Society.

Kodi Topamax imagwira ntchito bwanji kwa migraines?

M'malo mwake, chidutswa chake sichimadziwika.

Topiramate imagwira ntchito mosiyanasiyana, ndipo sizikudziwika kuti ndi yofunika iti ya mutu waching'alang'ala, akutero Dr. Friedman, pofotokoza kuti topiramate imagwira ntchito motsatira njira za sodium ndi calcium m'thupi, komanso pama receptor osiyanasiyana omwe mitsempha imatumiza ma sign.

Ponena kuti kupezeka kwa topiramate kumatha kusintha zizindikiritso za migraine, zinali mwangozi. Friedman akuti odwala khunyu amafotokoza kusintha kwa zizindikiritso zawo za migraine akamamwa topiramate ndi mankhwala ena ofanana nawo.

Kodi Topamax ndingatenge ndalama zingati za migraines?

Mlingo wa Topamax wa mutu waching'alang'ala nthawi zambiri umakhala wocheperako poyerekeza ndi wa khunyu, madokotala ambiri amayamba kutsika ndikuwonjezera kuchuluka pang'onopang'ono pakapita nthawi, malinga ndi Danny Park , MD, mutu wa gawo la mitsempha ku Sweden Covenant Hospital ku Chicago.

Mlingo woyambira umayamba ndi mapiritsi a 25 milligram kawiri tsiku lililonse, akutero. Kuti muchepetse zovuta, ndimangokulira ndi mamiligalamu 25 tsiku lililonse sabata [[ndi] mulingo wambiri wokhala pafupifupi mamiligalamu 100 tsiku lililonse.

Kodi zotsatira zoyipa kwambiri za Topamax za migraines ndi ziti?

Ngakhale kuti Topamax itha kukhala yopambana pochepetsa kuchepa kwa migraines, kupambana kumeneku kumabwera pamtengo - anthu ambiri amavutika kupirira zovuta zomwe zimachitika chifukwa cha mankhwalawa, zomwe Dr. Friedman akuti atha kuphatikizira:

• kumva kumva kulira, zikhomo ndi singano kumalekezero kapena pankhope
• kuchepa kwa njala kumabweretsa kuchepa thupi
• kugona / kugona
• nseru
• chifunga chaubongo

Dr. Park akuwonjezera kuti zotsatirazi zimatha kupezeka pamlingo wambiri wa topiramate kutengera wodwalayo.

Ndili ndi odwala ena omwe amafika ku mamiligalamu 100 kawiri patsiku [popanda zoyipa] ndipo mwatsoka odwala ena omwe samalekerera ngakhale mamiligalamu 25 tsiku lililonse, akutero.

Kodi Topamax ingakugwireni ntchito?

Simuyenera kukhala odwala matenda a mutu waching'alang'ala (mwachitsanzo, munthu amene ali ndi masiku 15 kapena kuposerapo a migraine pamwezi, malinga ndi American Migraine Foundation ) kuti mupindule ndi mankhwala oteteza ngati Topamax. Koma Dr. Friedman akuti odwala omwe amamvera mankhwalawa amakhala ndi zinthu zina zochepa zofanana.

Timaganizira zamankhwala ochepetsa migraine mwa anthu omwe ali ndi masiku osachepera anayi pamutu mwezi uliwonse olumala kwambiri chifukwa cha migraines, akutero, kutanthauza kuti migraine yanu imakulepheretsani kuchita ntchito zanu za tsiku ndi tsiku.

Ophatikizidwanso ndi anthu omwe alibe mpumulo wokwanira kuchipatala chowawa cha migraine komanso omwe ali ndi mitundu yapadera ya migraine (monga hemiplegic kapena ubongo wa aura ) mosasamala kuchuluka kwake.

Komabe, topiramate siyabwino kwa aliyense. Friedman akuti sichingatengedwe ali ndi pakati, ndipo angaganize kawiri za kupereka kwa munthu yemwe ali ndi mbiri ya miyala ya impso ya calcium chifukwa ena kufufuza akuwonetsa kuti topiramate imatha kuwonjezera chiopsezo chotenga matendawa.

Ubwino wotenga Topamax

Zingatenge kanthawi kuti mumve phindu lonse la Topamax chifukwa cha migraines-Dr. Friedman akuti anthu ambiri amawona kusintha m'mwezi woyamba, koma atha kupitilirabe bwino chaka choyamba. Ananenanso kuti mayesero am'mbuyomu azachipatala awonetsa anthu 50% akumva 50% bwino pa topiramate, pomwe ena amafotokoza kuyankha kwakukulu.

Koma zotsatira zoyipa ndizopweteka kwambiri topiramate; anthu ena sangathe kuwapirira.

Ndi 'mankhwala okonda kapena kuzida', akutero Dr. Friedman, ndipo nthawi zina anthu amawopa kuwamwa chifukwa amva za zoyipa zake. Koma sikuti aliyense amawapeza, chifukwa chake ndikofunikira kukhala omasuka nazo.