Waukulu >> Mankhwala Osokoneza Bongo Vs. Mnzanu >> Boniva vs. Fosamax: Kusiyana, kufanana, ndi zomwe zili zabwino kwa inu

Boniva vs. Fosamax: Kusiyana, kufanana, ndi zomwe zili zabwino kwa inu

Mankhwala osokoneza bongo Vs. Mnzanu

Boniva ndi Fosamax ndi mankhwala awiri omwe amathandizidwa ndi matenda a kufooka kwa mafupa. Osteoporosis ndi matenda am'mafupa. Zimachitika pamene kuchuluka kwa mchere wamafupa kapena mafupa amachepetsa, kapena pomwe fupa latsika. Fupa likuchepa, anthu amakhala pachiwopsezo chowonongeka cha mafupa, kapena mafupa osweka. Kuphulika kumeneku kumatha kuphatikizira kuphwanya kwa m'chiuno, mafupa am'mafupa, ndikuthyola fupa la chikazi ndi ntchafu.

Pali zinthu zambiri zomwe zingachepetse mwayi wanu wodwala kufooka kwa mafupa. Izi zimaphatikizapo kuchita masewera olimbitsa thupi komanso kuchita masewera olimbitsa thupi, kuchepetsa kumwa mowa, kupewa kusuta fodya, komanso kudya zakudya zokhala ndi vitamini D ndi calcium. Ngati dokotala akuwona kuti mukufunikira chithandizo chamankhwala a kufooka kwa mafupa, amatha kusankha Boniva ndi Fosamax, omwe ali mgulu la mankhwala omwe amadziwika kuti bisphosphonates. Pali njira zina zochiritsira matenda a kufooka kwa mafupa, monga Evista (raloxifene), Forteo (Teriparatide), Zotsatira (denosumab), calcitonin, ndi mankhwala a estrogen.

Kodi pali kusiyana kotani pakati pa Boniva ndi Fosamax?

Boniva (ibandronate) ndi mankhwala omwe amalembedwa ngati bisphosphonate. Bisphosphonates amagwira ntchito poletsa kufalikira kwa mafupa a osteoclast-mediated. Sizimaletsa kupanga mafupa. Mbadwo wachiwiri wa bisphosphonates, monga Fosamax, ndi oletsa ma osteoclast kwambiri kuposa am'badwo woyamba, monga Didronel (etidronate). Mitundu ina yachiwiri ya bisphosphonates imaphatikizapo Wachitetezo (risedronate), Fosamax (alendronate), Aredia (pamidronate), ndi Zosintha (zoledronic asidi). Boniva imapezeka piritsi limodzi lamphamvu la 150 mg. Boniva m'kamwa mwake amatengedwa kamodzi pamwezi. Boniva imapezekanso ngati yankho la jekeseni wa 3 mg / 3 ml.

Fosamax (alendronate) ndi mankhwala omwe amathandizanso m'badwo wachiwiri wa bisphosphonate. Fosamax imapezeka m'mapiritsi amlomo mwamphamvu za 5 mg, 10 mg, 35 mg, ndi 70 mg. Ikupezekanso mumayankho amlomo a 70 mg / 75 ml. Mlingo wa 5 mg ndi 10 mg amayenera kukhala kamodzi-tsiku lililonse. 35 mg ndi 70 mg ndimayeso kamodzi pamlungu.

Kusiyana kwakukulu pakati pa Boniva ndi Fosamax
	Boniva	Fosamax
Gulu la mankhwala osokoneza bongo	Bisphosphonates	Bisphosphonates
Chizindikiro cha Brand / generic	Zolemba ndi generic zilipo	Zolemba ndi generic zilipo
Kodi dzina lachibadwa ndi liti?	Zosakanikirana	Wophatikizira
Kodi mankhwalawa amabwera mwa mawonekedwe ati?	Mapiritsi apakamwa ndi yankho la jakisoni	Mapiritsi apakamwa ndi yankho la m'kamwa
Kodi mulingo woyenera ndi uti?	150 mg kamodzi pamwezi	70 mg kamodzi pamlungu
Kodi mankhwalawa amatenga nthawi yayitali bwanji?	Nthawi yayitali	Nthawi yayitali
Ndani amagwiritsa ntchito mankhwalawa?	Akuluakulu	Akuluakulu

Zomwe amathandizidwa ndi Boniva ndi Fosamax

Boniva ndi Fosamax amagwiritsidwa ntchito pochiza komanso kupewa kufooka kwa mafupa. Kwa Fosamax, izi zimaphatikizapo postmenopausal ndi corticosteroid-yomwe imayambitsa kufooka kwa mafupa. Boniva imavomerezedwa kuti igwiritsidwe ntchito mu postmenopausal, koma kagwiritsidwe kake ka corticosteroid-komwe kumayambitsa kufooka kwa mafupa sikupezeka. Kuchotsa pamakalata kumatanthauza kugwiritsa ntchito mankhwalawa ngati chisonyezo chomwe sichinavomerezedwe ndi Food and Drug Administration (FDA). Fosamax imavomerezedwanso pochiza matenda a Paget, komwe mafupa amakula ndikufooka kuposa masiku onse. Boniva imagwiritsidwanso ntchito potengera izi.

Mkhalidwe	Boniva	Fosamax
Chithandizo cha postmenopausal osteoporosis	Inde	Inde
Chithandizo cha Corticosteroid chomwe chimayambitsa kufooka kwa mafupa	Kutumiza	Inde
Postmenopausal kufooka kwa mafupa prophylaxis	Inde	Inde
Corticosteroid-yomwe imayambitsa kufooka kwa mafupa prophylaxis	Kutumiza	Inde
Matenda a Paget	Kutumiza	Inde
Hypercalcemia yoyipa	Kutumiza	Kutumiza
Zochitika zamafupa chifukwa cha mafupa a mafupa	Kutumiza	Ayi

Kodi Boniva kapena Fosamax ndi yothandiza kwambiri?

Therapy Oral Therapy Yomwe Ndi Mwezi Ndi Ibandronate Yophunzira Kufufuza kwa Osteoporosis Prevention, yomwe imadziwika kuti Mayeso oyenda , anaphatikiza azimayi opitilira 1,700 azaka zapakati pa azimayi azaka zapakati pa 55 ndi 84. Kafukufukuyu anayerekezera Boniva kamodzi pamwezi ndi Fosamax kamodzi pamlungu pokhudzana ndi kuthekera kwawo kukulitsa kuchuluka kwa mafupa (BMD) pamsana ndi m'chiuno chonse. Zotsatira zake zidawonetsa kuti kamodzi pamwezi Boniva samakhala wotsika kuposa Fosamax pankhani yamapeto iyi. Kuchepetsa chiwongola dzanja cha m'mafupa komanso kulolerana m'mimba kumafanananso.

Mlandu wa Boniva Alendronate mu Osteoporosis, kapena Chiyeso cha BALTO , adayesa zomwe odwala amakonda pakati pa Fosamax kamodzi pamlungu ndi Boniva kamodzi pamwezi. Zotsatira za mayesowa, owoloka mosiyanasiyana adapeza kuti odwala ambiri amakonda njira kamodzi pamwezi, pomwe 66.1% amakonda Boniva poyerekeza ndi 26.5% amakonda Fosamax. Zotsalirazo sizinasankhe zokonda pamtundu winawo.

Izi sizongokhala upangiri wa zamankhwala. Dokotala wanu yekha ndi amene angadziwe kuti ndi njira iti ya chithandizo yomwe ingakhale yoyenera kwa inu.

Kuphunzira ndi kuyerekezera mtengo wa Boniva vs. Fosamax

Boniva ndi mankhwala akuchipatala omwe nthawi zambiri amapangidwa ndi mapulani a inshuwaransi yamalonda ndi Medicare. Popanda inshuwaransi, ndalama zomwe mumapeza kamodzi pamwezi zitha kukuwonongerani $ 258 piritsi limodzi. Ndili ndi kuponi kuchokera ku SingleCare, mtengo wa Boniva wamba ungakhale wotsika mpaka $ 22.

Fosamax ndi mankhwala omwe amakupatsani ndi inshuwaransi yamalonda ndi Medicare. Kutenga mwezi umodzi kwa Fosamax kumatha kukuwonongerani $ 102 popanda inshuwaransi. Chiphaso cha SingleCare cha generic Fosamax zitha kuchepetsa mtengo kukhala wochepera $ 20.

	Boniva	Fosamax
Nthawi zambiri amakhala ndi inshuwaransi?	Inde	Inde
Nthawi zambiri amakhala ndi Medicare Part D?	Inde	Inde
Kuchuluka	Piritsi 1, 150 mg	4, 70 mg mapiritsi
Wopanga Medicare wamba	<$10	<$10
Mtengo wosakwatiwa	$ 22- $ 98	$ 16- $ 39

Zotsatira zoyipa za Boniva vs. Fosamax

Bisphosphonates amadziwika chifukwa cha chizolowezi chawo choyambitsa zovuta zam'mimba monga kupweteka m'mimba, nseru, kutsegula m'mimba, ndi kudzimbidwa. Odwala omwe ali ndi mbiri yamatenda am'mimba sangakhale oyenera kulandira mankhwala a bisphosphonate chifukwa ali pachiwopsezo chachikulu chotenga zotsatirazi ali pa bisphosphonate therapy. Izi zimachitika nthawi zina zimakhala zovuta mokwanira kufunikira kuchipatala.

Fosamax ndi Boniva onse amadziwika kuti amayambitsa zowawa zam'mafupa m'mafupa, minofu, ndi mafupa.

Boniva yadziwika kuti imalumikizidwa ndi kuthamanga kwa magazi komanso kusowa tulo, kapena kugona movutikira.

Tchati chotsatirachi sichiyenera kukhala mndandanda wazinthu zonse zomwe zingachitike chifukwa cha Fosamax ndi Boniva. Chonde funsani omwe akukuthandizani kuti mupeze mndandanda wathunthu.

	Fosamax	Boniva
Zotsatira zoyipa	Zoyenera?	Pafupipafupi	Zoyenera?	Pafupipafupi
Kupweteka m'mimba	Inde	6.6%	Inde	7.8%
Nseru	Inde	3.6%	Inde	5.1%
Dyspepsia	Inde	3.6%	Inde	5.6%
Kudzimbidwa	Inde	3.1%	Inde	4.0%
Kutsekula m'mimba	Inde	3.1%	Inde	5.1%
Kudzikweza	Inde	2.6%	Ayi	N / A
Kubwezeretsanso kwa acid	Inde	2.0%	Ayi	N / A
Zilonda zam'mimba	Inde	1.5%	Ayi	N / A
Kusanza	Inde	1.0%	Ayi	N / A
Dysphagia	Inde	1.0%	Ayi	N / A
Kutsegula m'mimba	Inde	1.0%	Ayi	N / A
Matenda a m'mimba	Inde	0.5%	Inde	awiri%
Kupweteka kwa minofu	Inde	4.1%	Inde	4.5%
Mutu	Inde	2.6%	Ayi	N / A
Lawani zopotoza	Inde	0.5%	Ayi	N / A
Matenda oopsa	Ayi	N / A	Inde	6.3%
Myalgia	Ayi	N / A	Inde	2.0%
Kutupa	Ayi	N / A	Inde	2.3%
Kusowa tulo	Ayi	N / A	Inde	2.0%

Gwero: Fosamax ( Tsiku ndi Tsiku Boniva ( Tsiku ndi Tsiku )

Kuyanjana kwa mankhwala a Boniva vs. Fosamax

Boniva ndi Fosamax akapatsidwa calcium yokhala ndi zowonjezera kapena ma antacids, calcium imatha kusokoneza kuyamwa kwa Fosamax. Odwala mafupa ambiri amafunika kutenga calcium calcium, chifukwa chake tikulimbikitsidwa kuti mudikire mphindi 30 mutatenga Fosamax kuti mutenge calcium kapena mankhwala ena aliwonse am'kamwa.

Mankhwala osagwiritsidwa ntchito poletsa kutupa (NSAIDs) amalumikizidwa pawokha ndi zovuta zam'mimba zofananira ndi bisphosphonates. Sitikulimbikitsidwa kumwa mankhwala osagwirizana a NSAID pamene mukumwa bisphosphonates.

Pali umboni wina wosonyeza kuti kupatsa bisphosphonates ndi H2-blockers, mawonekedwe am'mimba amchere ochepetsa am'mimba, kumawonjezera kupezeka kwa mankhwala a bisphosphonate.

Tchati ichi sichikutchula zochitika zilizonse zomwe zimadziwika ndi mankhwala. Chonde funsani akatswiri azaumoyo kuti mumve mndandanda wathunthu.

Mankhwala osokoneza bongo	Gulu la mankhwala osokoneza bongo	Fosamax	Boniva
Calcium Zotayidwa Mankhwala enaake a Chitsulo	Mitundu yambiri ya cation yowonjezera ndi ma antacids	Inde	Inde
Asipilini Zamgululi Naproxen Diclofenac Ketorolac Meloxicam Alireza	Mankhwala Osokoneza Bongo Osagwiritsa Ntchito Matenda (NSAIDS)	Inde	Inde
Chotchuka Ranitidine	Oletsa H2	Inde	Inde

Machenjezo a Boniva ndi Fosamax

Kuchotsa mano mukamamwa mankhwala a bisphosphonate kumatha kuwonjezera chiopsezo chokhala ndi matenda a osteonecrosis a nsagwada (ONJ), kapena kufa pang'ono kwa nsagwada. Asanayambe mankhwala a bisphosphonate, odwala ayenera kuyezetsa mano ndikuganiza zodzitchinjiriza kapena kuwongolera mano asanayambe mankhwala.

Odwala omwe ali ndi zotupa zam'mimba monga Barrett's esophagus, dysphagia, kapena zilonda atha kukulitsa matenda awo ndi ma bisphosphonates. Chifukwa cha chizolowezi chawo chokwiyitsa mucosa ya kum'mero, ma bisphosphonates amayenera kutengedwa m'mawa m'mawa ndikumwa madzi pang'ono. Mankhwala ena, zakumwa, ndi chakudya ziyenera kupewedwa kwa mphindi 30, koma kwa maola awiri. Odwala ayenera kukhala owongoka kwa mphindi zosachepera 30 atamwa mankhwalawo. Iwo sayenera kugona pansi. Izi zimachepetsa kukwiya kwam'mimba.

Odwala omwe ali ndi calcium yotsika, kapena hypocalcemia, ayenera kutenga njira zofunikira kuti athetse kashiamu wawo asanayambe mankhwala a bisphosphonate. Odwala amatha kupitiliza mankhwala a calcium akangoyamba bisphosphonates bola akamatsata malangizo kuti alekanitse kashiamu wawo ndi bisphosphonate.

Fosamax ndi Boniva ayenera kugwiritsidwa ntchito mosamala kwa odwala omwe ali ndi vuto la impso kapena matenda a impso. Ntchito yaimpso iyenera kuyang'aniridwa chifukwa kuchepa kwa ntchito yaimpso kumatanthauza kuti simungathe kuchotsa mankhwalawa mthupi lanu momwe angathere ndipo mankhwalawa amatha kudziunjikira mthupi lanu.

Mafunso omwe amafunsidwa pafupipafupi za Boniva vs. Fosamax

Boniva ndi chiyani?

Boniva ndi mankhwala akuchipatala m'kalasi lotchedwa bisphosphonates. Amagwiritsidwa ntchito pochiza komanso kupewa kufooka kwa mafupa. Boniva imapezeka ngati yankho lamitsempha komanso piritsi kamodzi pamwezi.

Fosamax ndi chiyani?

Fosamax ndimankhwala amankhwala m'kalasi la mankhwala omwe amadziwika kuti bisphosphonates. Amagwiritsidwa ntchito pochiza ndi kupewa kufooka kwa mafupa. Fosamax imapezeka m'mapiritsi amlomo tsiku lililonse, kamodzi pamapiritsi amlomo mlungu uliwonse, komanso yankho lamlomo.

Kodi Boniva ndi Fosamax ali ofanana?

Boniva ndi Fosamax ndi bisphosphonates am'badwo wachiwiri, koma sizofanana ndendende. Kusiyanitsa kwawo kwakukulu ndi momwe amathandizidwira. Boniva imatha kuperekedwa kamodzi pamwezi, pomwe Fosamax imatha kuperekedwa kamodzi tsiku lililonse kapena kamodzi pamlungu.

Kodi Boniva kapena Fosamax ndibwino?

Kafukufuku wasonyeza kuti Boniva ndi Fosamax ali ndi zotsatira zofananira zamankhwala zokhudzana ndi thanzi la mafupa, komabe, kafukufuku m'modzi wasonyeza kuti odwala ambiri amakonda njira yolembera ya Boniva kamodzi pamwezi.

Kodi nditha kugwiritsa ntchito Boniva kapena Fosamax ndili ndi pakati?

Palibe Boniva kapena Fosamax omwe adaphunziridwa mwa amayi apakati. Ntchito zawo ziyenera kupewedwa mwa amayi apakati kuti zisawonongeke kwa mwana wosabadwayo.

Kodi ndingagwiritse ntchito Boniva kapena Fosamax ndi mowa?

Mowa ndi zakumwa zonse ziyenera kupewedwa kwakanthawi mutatenga Boniva kapena Fosamax kuti mupewe kukwiya. Kumwa mowa moyenerera kumalumikizidwa ndi zoopsa zazikulu za kufooka kwa mafupa, chifukwa chake ndibwino kuchepetsa kumwa.

Kodi mankhwala abwino kwambiri komanso otetezeka bwanji kufooka kwa mafupa?

Pulogalamu ya National Osteoporosis Foundation Amapereka malangizo othandizira kuchiza matenda a kufooka kwa mafupa. Bisphosphonates monga Fosamax, Boniva, Reclast, ndi Actonel amawerengedwa kuti ndi mankhwala oyamba komanso malangizo ena monga calcium calcium ndi kuchita masewera olimbitsa thupi.

Kodi Boniva amachulukitsa kuchuluka kwa mafupa?

Boniva imagwirizanitsidwa ndi kuwonjezeka kwakukulu kwa kuchuluka kwa mchere wamafupa (BMD). Izi zimachepetsa chiopsezo chothyoka kwa odwala kufooka kwa mafupa.

Muyenera kumwa calcium ndi Boniva?

Simuyenera kumwa calcium panthawi imodzimodzi ndi Boniva, koma mutha kumwa calcium chifukwa cha mafupa mukamalandira mankhwala a Boniva. Muyenera kudikirira osachepera mphindi 30 mutalandira mankhwala anu a bisphosphonate musanadye calcium supplement.