Celebrex vs. ibuprofen: Kusiyana, kufanana, ndi zomwe zili zabwino kwa inu

Mankhwala osokoneza bongo Vs. Mnzanu

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Matenda a nyamakazi amadziwika kuti amayambitsa zowawa. Pali mankhwala ambiri kunja kwa ululu wamatenda omwe amatha kusokoneza omwe angatenge. Mankhwala awiri omwe amapezeka mu NSAID (nonsteroidal anti-inflammatory drug) ndi Celebrex (celecoxib) ndi ibuprofen.

NSAID zitha kukhala zothandiza pochiza nyamakazi ya nyamakazi ndi nyamakazi, komanso mitundu ina. Onse a Celebrex ndi ibuprofen amapezeka mu mawonekedwe achibadwa. Ngakhale Celebrex imangopezeka mwa mankhwala, mutha kugula mankhwala ochepa a ibuprofen pompopompo. Mlingo wapamwamba wa ibuprofen umapezeka ndi mankhwala. Chifukwa Celebrex ndi ibuprofen ali mgulu limodzi la mankhwala, ndi ofanana, koma amakhalanso ndi kusiyana kwakukulu.

Kodi pali kusiyana kotani pakati pa Lexapro ndi Zoloft?

Kusiyana kwakukulu pakati pa Celebrex ndi ibuprofen
	Zamgululi	Zamgululi
Gulu la mankhwala osokoneza bongo	NSAID, COX-2 choletsa	NSAID
Chizindikiro cha Brand / generic	Brand ndi generic	Rx: generic OTC: mtundu ndi generic
Kodi dzina lachibadwa ndi liti? Kodi dzina lake ndi ndani?	Zowonjezera: celecoxib	Mtundu: Motrin, Advil (OTC)
Kodi mankhwalawa amabwera mwa mawonekedwe ati?	Makapisozi (50, 100, 200, 400 mg) Fomu yamadzimadzi ya ana imaphatikizidwa ndi mankhwala	Mapiritsi a mphamvu: 400 mg, 600 mg, 800 mg NKHANI: Mapiritsi 200 mg / makapisozi / zofewa, zotsekemera zosiyanasiyana, zakumwa, ndi madontho
Kodi mulingo woyenera ndi uti?	Akuluakulu: 200 mg tsiku ndi chakudya; pazipita 400 patsiku Njira: 100 mg kawiri tsiku lililonse Ana azaka ziwiri kapena kupitilira apo: zimatengera kulemera	Akuluakulu: 200 mpaka 800 mg katatu kapena kanayi tsiku lililonse ndi chakudya; Mlingo waukulu umasiyanasiyana kutengera momwe zinthu zilili Ana: amasiyanasiyana kutengera msinkhu, kulemera, ndi kapangidwe kake
Kodi mankhwalawa amatenga nthawi yayitali bwanji?	Zimasintha: milungu mpaka zaka	Zimasintha: masiku mpaka milungu, odwala ena amatenga miyezi kapena zaka
Ndani amagwiritsa ntchito mankhwalawa?	Ana azaka ziwiri kapena kupitilira apo; akuluakulu	Ana miyezi isanu ndi umodzi kapena kupitirira; akuluakulu

Mukufuna mtengo wabwino pa Celebrex?

Lowani zidziwitso za mtengo wa Celebrex kuti mudziwe kuti mitengo isintha liti!

Pezani zidziwitso zamitengo

Zomwe amathandizidwa ndi Celebrex ndi Ibuprofen

Celebrex, mankhwala osagwiritsidwa ntchito poletsa kutupa (NSAID), ndi anasonyeza pazifukwa zotsatirazi: nyamakazi ya nyamakazi, nyamakazi ya nyamakazi, nyamakazi ya ana kwa zaka ziwiri kapena kupitilira apo, ankylosing spondylitis, kupweteka kwambiri, dysmenorrhea, komanso banja la adenomatous polyposis monga cholumikizira chisamaliro chachizolowezi.

Ibuprofen imakhalanso NSAID ndipo imawonetsedwa kuti ithetse vuto la matenda a nyamakazi ndi nyamakazi, kupweteka pang'ono pang'ono, komanso dysmenorrhea.

Mkhalidwe	Zamgululi	Zamgululi
Nyamakazi ya nyamakazi	Inde	Inde
Matenda a nyamakazi	Inde	Inde
Matenda a nyamakazi a achinyamata (mwa odwala azaka ziwiri kapena kupitilira apo)	Inde	Ayi
Ankylosing spondylitis	Inde	Ayi
Kupweteka kwambiri	Inde	Ayi
Matenda oyambira m'mimba	Inde	Inde
Wodziwika bwino adenomatous polyposis ngati chithandizo chothandizira	Inde	Ayi
Kupweteka pang'ono pang'ono	Ayi	Inde

Mankhwala a NSAID amagwira ntchito poletsa ma prostaglandin (ma prostaglandin amachititsa kupweteka ndi kutupa) kuti asapangidwe. Prostaglandin imapangidwa ndi michere iwiri, cyclooxygenase-1 (COX-1) ndi cyclooxygenase-2 (COX-2).

Kodi Celebrex kapena Ibuprofen ndi yothandiza kwambiri?

Celebrex imadziwika kuti COX-2 inhibitor yosankha. Ngakhale akadali NSAID ngati ibuprofen, Celebrex imangoletsa COX-2, mosiyana ndi ibuprofen, yomwe imatseka COX-1 ndi COX-2. Kodi izi zikutanthauza chiyani? COX-2 inhibitor imatha kukhala yosavuta m'mimba, yomwe imatha kuyambitsa zilonda zam'mimba.

Mu maphunziro azachipatala kuti zitheke, Celebrex adawonetsa:

• Kuchepetsa kupweteka kwamalumikizidwe a odwala osteoarthritis
• Kuchepetsa kupweteka kwamalumikizidwe ndi kutupa kwa nyamakazi ya nyamakazi
• Kupititsa patsogolo kwa odwala omwe ali ndi nyamakazi ya achinyamata
• Kupititsa patsogolo kwa odwala omwe ali ndi ankylosing spondylitis (kupweteka kwambiri, matenda, ndi kuwonongeka kwa ntchito)
• Mpumulo wa kupweteka pang'ono kapena kopweteka komwe kumayambitsidwa ndi kupweteka kwa opaleshoni kapena dysmenorrhea

M'maphunziro azachipatala othandizira, ibuprofen kuwonetsedwa :

• Zotsatira zofananira kwa aspirin mwa odwala osteoarthritis ndi nyamakazi ya nyamakazi ya ululu ndi kutupa
• Mpumulo wa ululu wa episiotomy, njira zamano, ndi dysmenorrhea

Ndi mankhwala ati omwe ndi othandiza kwambiri? Ndizovuta kunena. Mmodzi kuphunzira , Celebrex adawonetsedwa kuti ndi othandiza ngati ibuprofen kwa odwala osteoarthritis a bondo. Kafukufuku wina akuwonetsa ibuprofen kukhala ogwira mtima, pomwe ena akumaliza Zamgululi zitha kukhala zothandiza kwambiri.

Pankhani yachitetezo, mayesero azachipatala a Celebrex, komanso ma NSAID omwe sanasankhe (monga ibuprofen) mpaka zaka zitatu awonetsa chiwopsezo chowonjezeka cha zochitika zamtima, kupwetekedwa mtima, ndi sitiroko, zomwe zitha kupha. Chifukwa chake, ma NSAID onse (kuphatikiza onse a Celebrex ndi ibuprofen) atha kukhala pachiwopsezo chotere. Komanso, ma NSAID onse, kuphatikiza Celebrex ndi ibuprofen, ali ndi chiopsezo chowonjezeka cha zochitika za GI, monga kutuluka magazi ndi zilonda.

Mankhwala abwino kwa inu angadziwike kokha ndi omwe amakuthandizani pa zaumoyo, omwe angaganizire chithunzi chonse cha matenda anu, zoopsa, mbiri yaumoyo wanu, ndi mankhwala ena omwe mukumwa.

Mukufuna mtengo wabwino kwambiri pa Ibuprofen?

Lowani zidziwitso zamitengo ya Ibuprofen ndikupeza kuti mitengo ikasintha liti!

Pezani zidziwitso zamitengo

Kuwerengera ndi kuyerekezera mtengo wa Celebrex vs. Ibuprofen

Celebrex imakhala ndi inshuwaransi ndipo Medicare Part D mumtundu wake wa celecoxib. Mankhwala enieni angakhale a makapisozi 30 a 200 mg celecoxib. Mtengo wakuthumba uli pafupifupi $ 217.49 koma mutha kupeza celecoxib ya $ 105-145 kuma pharmacies omwe akutenga nawo gawo ndi coupon ya SingleCare.

Ibuprofen nthawi zambiri imakhala ndi inshuwaransi ndi Medicare Part D, mu mphamvu zamankhwala 400 mg, 600 mg, ndi 800 mg. Malangizo a Doctor amasiyana. Mwachitsanzo, mtengo wogulitsa mapiritsi 30 a 800 mg ibuprofen umawononga kulikonse kuyambira $ 6-30. Ndi coupon ya SingleCare, mtengo wa ibuprofen ndi $ 4-8.

	Zamgululi	Zamgululi
Nthawi zambiri amakhala ndi inshuwaransi?	Inde; generic	Inde; mphamvu ya mankhwala
Nthawi zambiri amakhala ndi Medicare Part D?	Inde; generic	Inde; mphamvu ya mankhwala
Mlingo woyenera	30, 200 mg makapisozi a generic celecoxib	30, 800 mg mapiritsi a ibuprofen
Chitsanzo cha Medicare Part D copay	$ 0-150	$ 0-14
Mtengo wosakwatiwa	$ 105-145	$ 4-8

Zotsatira zoyipa za Celebrex vs. Ibuprofen

Zochitika zofala kwambiri za Celebrex ndi ibuprofen zimaphatikizapo kupweteka m'mimba, kutsegula m'mimba, kudzimbidwa, komanso kupweteka mutu. Onani gawo lochenjeza kuti mumve zambiri za chiwopsezo cha mtima ndi chiopsezo cha kutuluka kwa magazi mu GI.

	Zamgululi	Zamgululi
Zotsatira zoyipa	Zoyenera?	Pafupipafupi	Zoyenera?	Pafupipafupi *
Kupweteka m'mimba	Inde	4.1%	Inde	3-9%
Kutsekula m'mimba	Inde	5.6%	Inde	3-9%
Dyspepsia (kudzimbidwa)	Inde	8.8%	Inde	3-9%
Mutu	Inde	15.8%	Inde	3-9%

* Pafupipafupi zotsatira zoyipa za ibuprofen sizimaperekedwa ndi chidziwitso cha mankhwala; kokha kuti zotsatirazi zidachitika mu 3-9% ya odwala.

Gwero Tsiku ndi Tsiku (Celebrex) , Tsiku ndi Tsiku ( ibuprofen )

Ili si mndandanda wathunthu; Zotsatira zina zimatha kuchitika. Lumikizanani ndi omwe amakuthandizani kuti mumve zambiri.

Kuyanjana kwa mankhwala a Celebrex ndi Ibuprofen

Celebrex ndi ibuprofen zimagwirizana chimodzimodzi ndi mankhwala ena. Mankhwala onsewa amalumikizana ndi owonda magazi monga Coumadin (warfarin), mankhwala ena am'magazi (ACE inhibitors, ARBs, ndi beta blockers), antidepressants, ndi diuretics monga hydrochlorothiazide ndi methotrexate. Funsani omwe akukuthandizani kuti akuthandizeni.

Mowa ayenera kupewedwa mukamamwa Celebrex kapena ibuprofen. Kugwiritsa ntchito imodzi mwa mankhwalawa ndi mowa kumatha kuwonjezera ngozi ya GI (m'mimba) kutuluka magazi kapena kutupa. Kuphatikizaku kungayambitsenso impso kapena kulephera kwa impso.

Ili ndi mndandanda wamagulu azomwe zimachitika ndi mankhwala. Lumikizanani ndi omwe amakuthandizani kuti mumve zambiri.

Mankhwala osokoneza bongo	Gulu la Mankhwala	Zamgululi	Zamgululi
Coumadin (warfarin)	Wotsutsa	Inde	Inde
Zestril (lisinopril), Cozaar (losartan), ndi ena	ACE zoletsa, ma ARB	Inde	Inde
Tenormin (atenolol), Toprol XL kapena Lopressor (metoprolol)	Oletsa Beta	Inde	Inde
Diflucan (fluconazole)	Zosakanikirana	Inde	Ayi
Lasix (furosemide), hydrochlorothiazide	Okodzetsa	Inde	Inde
Naproxen, Mobic (meloxicam)	Ma NSAID ena	Inde	Inde
Methotrexate	Antimetabolite	Inde	Inde
Zoloft (sertraline), Paxil (paroxetine), Prozac (fluoxetine), Effexor (venlafaxine), Desyrel (trazodone), Elavil (amitriptyline), ndi zina	Mankhwala opatsirana	Inde	Inde
Mowa	Mowa	Inde	Inde

Machenjezo a Celebrex ndi Ibuprofen

Celebrex iyenera kupewedwa mwa odwala omwe sagwirizana ndi ma NSAID, komanso odwala omwe sagwirizana ndi sulfa. Ibuprofen iyenera kupewedwa mwa odwala omwe sagwirizana ndi ma NSAID.

Chifukwa mankhwala onsewa ndi ma NSAID, Celebrex ndi ibuprofen ali ndi machenjezo omwewo. Ali ndi chenjezo la nkhonya (chenjezo lamphamvu kwambiri malinga ndi Food and Drug Administration, kapena FDA). Celebrex kapena ibuprofen imachulukitsa chiopsezo cha zochitika zazikulu zamtima, MI (myocardial infarction, kapena matenda amtima), ndi stroke, zonse zomwe zitha kupha. Ma NSAID onse ali ndi chiopsezo chofananacho, chomwe chimakulitsa momwe mumagwiritsira ntchito nthawi yayitali. Odwala omwe ali ndi matenda amtima kapena omwe ali ndi ziwopsezo zamtima ali pachiwopsezo chachikulu. Celebrex kapena ibuprofen sayenera kugwiritsidwa ntchito kupweteka pakamayendedwe ka mitsempha yodutsa magazi (CABG).

Komanso mu chenjezo lomwe lili m'bokosili muli chiwopsezo cha matenda opatsirana pogonana, kapena zochitika m'mimba, kuphatikiza kutuluka magazi, zilonda zam'mimba, ndi kutuluka kwa m'mimba kapena m'matumbo, komwe kumatha kupha. Zina mwa zochitikazi zitha kuchitika nthawi iliyonse, popanda zidziwitso. Odwala okalamba komanso omwe ali ndi zilonda zam'mimba kapena magazi a GI ali pachiwopsezo chachikulu cha zochitika zazikulu za GI.

Machenjezo ena a Celebrex ndi ibuprofen ndi awa:

• Kuopsa kwa michere yayikulu ya chiwindi ndipo, kawirikawiri, kusintha kwakukulu kwa chiwindi.
• Matenda atsopano kapena kuwonjezeka kwa matenda oopsa (kuthamanga kwa magazi). Gwiritsani ntchito mosamala odwala matenda oopsa; onetsetsani kuthamanga kwa magazi kwambiri mukamalandira chithandizo.
• Kusungidwa kwamadzimadzi ndi edema. Gwiritsani ntchito mosamala kwa odwala omwe amasunga madzi kapena osagwira mtima
• Aimpso papillary necrosis / vuto lina la impso pogwiritsa ntchito nthawi yayitali. Gwiritsani ntchito mosamala okalamba, odwala omwe ali ndi vuto la impso, mtima wosagwira, chiwindi, komanso odwala omwe amatenga okodzetsa, ACE inhibitors, kapena angiotensin II blockers.
• Zochita za Anaphylactoid. Musagwiritse ntchito kwa odwala omwe ali ndi Atatu mwa Samter .
• Khungu lalikulu limatha kuchitika monga exfoliative dermatitis, matenda a Stevens-Johnson (SJS), ndi poizoni epidermal necrolysis (TEN), yomwe imatha kupha komanso kumachitika popanda chenjezo. Siyani Celebrex ndipo pitani kuchipatala pakagwa zotupa kapena khungu.

Pali zochepa pa ma NSAID omwe amagwiritsidwa ntchito ali ndi pakati. Kugwiritsa ntchito ma NSAID onse, kuphatikiza onse a Celebrex ndi ibuprofen, mkati mwa gawo lachitatu la mimba, kumaonjezera ngozi Kutseka msanga kwa fetus ductus arteriosus . Chifukwa chake, ma NSAID sayenera kugwiritsidwa ntchito pakatha milungu makumi atatu ali ndi pakati.

Funsani wothandizira zaumoyo wanu za Celebrex kapena ibuprofen pogwiritsa ntchito mimba. Ngati mukumwa kale Celebrex kapena ibuprofen ndikupeza kuti muli ndi pakati, funsani omwe amakuthandizani kuti akuthandizeni.

Pali zochepa pazokhudza Celebrex ndi ibuprofen poyamwitsa; funsani dokotala wanu kuti akuthandizeni.

Mafunso omwe amafunsidwa pafupipafupi za Celebrex vs. Ibuprofen

Kodi Celebrex ndi chiyani?

Celebrex ndi nonsteroidal anti-inflammatory drug (NSAID) yomwe ikuwonetsedwa pazifukwa izi: nyamakazi, nyamakazi, nyamakazi ya nyamakazi mwa odwala azaka ziwiri kapena kupitilira apo, ankylosing spondylitis, kupweteka kwambiri, dysmenorrhea, komanso banja adenomatous polyposis monga cholozerana mwachizolowezi kusamalira.

Kodi Ibuprofen ndi chiyani?

Ibuprofen ndi NSAID ndipo amagwiritsidwa ntchito pochiza matenda a osteoarthritis, nyamakazi ya nyamakazi, kupweteka pang'ono mpaka pang'ono, ndi dysmenorrhea yoyamba.

Kodi Celebrex ndi Ibuprofen ndi ofanana?

Chifukwa mankhwala onsewa ndi ma NSAID, ndi ofanana ndipo amakhala ndi zovuta zina komanso machenjezo. Amasiyana ndi ziwonetsero ndi mtengo. Onani pamwambapa kuti mudziwe zambiri pazofanana komanso kusiyana.

Kodi Celebrex kapena Ibuprofen ndibwino?

Mankhwala onsewa atha kukhala othandiza pochiza nyamakazi komanso zinthu zina. Kutengera mtundu wa matenda omwe mukukumana nawo, komanso kulingalira za matenda ena aliwonse omwe mungakhale nawo, komanso mankhwala ena omwe mukumwa, dokotala wanu akhoza kukuthandizani mankhwala oyenera kwa inu.

Kodi nditha kugwiritsa ntchito Celebrex kapena Ibuprofen ndili ndi pakati?

Mukazindikira kuti muli ndi pakati ndikugwiritsa ntchito Celebrex kapena ibuprofen funsani omwe amakuthandizani kuti akuthandizeni.

Amayi oyembekezera sayenera kugwiritsa ntchito ma NSAID awa pakatha milungu makumi atatu ali ndi pakati. Kugwiritsa ntchito Celebrex ndi ibuprofen mkati mwa gawo lachitatu la mimba kumatha kuonjezera chiopsezo chotsekedwa msanga kwa fetus ductus arteriosus.

Kodi ndingagwiritse ntchito Celebrex kapena Ibuprofen ndi mowa?

Ayi . Kugwiritsa ntchito imodzi mwa mankhwalawa ndi mowa kumatha kuwonjezera ngozi ya GI (m'mimba) kutuluka magazi kapena kutupa m'mimba. Kuphatikizaku kungayambitsenso impso kapena kulephera kwa impso.

Kodi Celebrex ndi yothandiza kwambiri kuposa ibuprofen?

Mankhwala onsewa amatha kukhala othandiza kuthana ndi matenda a nyamakazi komanso mavuto ena. Lumikizanani ndi omwe amakuthandizani kuti muphunzire mankhwala omwe angakuthandizeni ngati mutapatsidwa matenda, mbiri yaumoyo, ndi mankhwala ena omwe mungakhale mukumwa.

Chifukwa chiyani adachotsa Celebrex pamsika?

Celebrex akadali pamsika monga lero. Vioxx (rofecoxib), mankhwala ofanana ndi a Celebrex, anali kuchotsedwa kuchokera kumsika ndi wopanga, Merck, mu 2004, chifukwa cha chiwopsezo chowonjezeka cha zochitika zamtima ndi ntchito yayitali. Mu 2005, mankhwala ena ofanana, Bextra (valdecoxib), anali adachoka pamsika ndi Pfizer wopanga pazifukwa zomwezo.

Kodi Celebrex ndiopweteka?

Celebrex ndi mankhwala a NSAID (nonsteroidal anti-inflammatory) omwe amathandiza ndi zisonyezo zowawa komanso zotupa kuchokera kuzinthu zosiyanasiyana (onani pamwambapa). Chifukwa chimangogwira ntchito pa michere ya COX-2, itha kukhala yotetezeka m'mimba, ngakhale pali chiopsezo cha GI.