Etodolac vs. ibuprofen: Kusiyana, kufanana, ndi zomwe zili zabwino kwa inu
Mankhwala osokoneza bongo Vs. MnzanuKuwunika kwa mankhwala osokoneza bongo & kusiyana kwakukulu | Zinthu zothandizira | Mphamvu | Kuphunzira inshuwaransi ndikufanizira mtengo | Zotsatira zoyipa | Kuyanjana kwa mankhwala | Machenjezo | FAQ
Palibe amene akufuna kukhala ndi zovuta kapena zopweteka kwa nthawi yayitali, kapena konse pazomwezo. Mwamwayi, mankhwala opatsirana ndi omwenso amathandizidwa amatha kupezeka ku sitolo yogulitsira mankhwala yapafupi. Ngakhale sali olimba ngati opioid opweteka, omwe amafunikira kuwunika kozama kwamankhwala ndi mankhwala, ma NSAID ngati etodolac kapena ibuprofen ndi othandiza kuthana ndi ululu wofatsa pang'ono.
Mwinanso amadziwika kuti nonsteroidal anti-inflammatory drugs, ma NSAID amagwira ntchito poletsa kupanga ma prostaglandins. Thupi lanu limatha kuyankha kuzipatala zina popanga ma prostaglandins, omwe ndi mankhwala omwe amachititsa kupweteka, kutupa, ndi malungo. Ma NSAID amaletsa ma enzyme opanga ma prostaglandin-COX-1 ndi COX-2-kuti athetse kuyankha kwamthupi kotupa ndikuchepetsa kupweteka.
Etodolac ndi ibuprofen amadziwika kuti ma NSAID. Komabe, ali ndi kusiyana kofunikira.
Kodi pali kusiyana kotani pakati pa etodolac ndi ibuprofen?
Etodolac nthawi zina imadziwika ndi dzina lake (lomwe lasiya tsopano), Lodine. Amapezeka ngati mankhwala achibadwa ndipo amatha kupezeka ndi mankhwala a dokotala.
Etodolac amakhala ndi theka la maola pafupifupi asanu ndi limodzi kapena asanu ndi awiri ndipo amafika pachimake m'magazi ola limodzi kapena awiri atamwa. Nthawi zambiri amatengedwa kawiri kapena katatu tsiku lililonse chifukwa cha kupweteka kwa nyamakazi. Palinso piritsi lotulutsira etodolac lomwe limakhala ndi theka la moyo pafupifupi maola asanu ndi atatu ndipo limatha kumwedwa kamodzi tsiku lililonse.
Ibuprofen ndi NSAID yofala kwambiri yomwe imapezeka pa-counter (OTC). Mphamvu zazikulu za ibuprofen zimapezekanso ndi mankhwala akuchipatala. Mayina odziwika bwino a ibuprofen ndi Advil, Motrin, ndi Midol.
Ibuprofen amafika pachimake m'magazi pasanathe ola limodzi kapena awiri atamwa. Komabe, mosiyana ndi etodolac, ibuprofen amakhala ndi theka lanthawi yayitali yozungulira maola awiri . Ibuprofen wokhala ndi mphamvu yamankhwala amabwera piritsi lomwe nthawi zambiri limatengedwa katatu kapena kanayi tsiku lililonse. Mtundu wa OTC umabwera m'mapiritsi apakamwa, makapisozi, ndi kuyimitsidwa kwamadzi.
| Kusiyana kwakukulu pakati pa etodolac ndi ibuprofen | ||
|---|---|---|
| Etodolac | Zamgululi | |
| Gulu la mankhwala osokoneza bongo | Mankhwala osagwiritsidwa ntchito poletsa kutupa (NSAID) | Mankhwala osagwiritsidwa ntchito poletsa kutupa (NSAID) |
| Chizindikiro cha Brand / generic | Zowonjezera zilipo (mtundu watha) | Zolemba ndi generic zilipo |
| Kodi dzina lake ndi ndani? | Lodine | Advil, Motrin, Midol |
| Kodi mankhwalawa amabwera mwa mawonekedwe ati? | Makapisozi apakamwa Piritsi lapakamwa Piritsi lapakamwa, kutulutsa kwina | Makapisozi apakamwa Piritsi lapakamwa Madzi amlomo Jekeseni (NeoProfen) |
| Kodi mulingo woyenera ndi uti? | Zowawa: 200 mpaka 400 mg maola 6 kapena 8 aliwonse pakufunika. Musapitirire mlingo wambiri wa 1200 mg patsiku. Kwa nyamakazi ya nyamakazi kapena nyamakazi: Kutulutsa msanga 300 mg kawiri kapena katatu tsiku lililonse kapena 400 mpaka 500 mg kawiri tsiku lililonse. Kutulutsa kowonjezera 400 mpaka 1000 mg kamodzi tsiku lililonse. Musapitirire mlingo wambiri wa 1200 mg patsiku. | Zowawa: 200 mpaka 400 mg maola 4 kapena 6 aliwonse pakufunika. Musapitirire mlingo wokwanira wa 1200 mg patsiku pokhapokha mutalangizidwa ndi dokotala. Kwa nyamakazi ya nyamakazi kapena nyamakazi: 400 mpaka 800 mg katatu kapena kanayi tsiku lililonse. Musapitirire kuchuluka kwa 3200 mg patsiku. |
| Kodi mankhwalawa amatenga nthawi yayitali bwanji? | Kutalika kwa chithandizo kumatengera thanzi, kupweteka, ndi zina. Chithandizo chitha kukhala chanthawi yayitali kapena chanthawi yayitali. | Kutalika kwa chithandizo kumatengera thanzi, kupweteka, ndi zina. Chithandizo chitha kukhala chanthawi yayitali kapena chanthawi yayitali. |
| Ndani amagwiritsa ntchito mankhwalawa? | Akuluakulu ndi ana azaka 6 kapena kupitilira apo | Akuluakulu ndi ana miyezi 6 kapena kupitilira apo |
Zinthu zomwe zimachitidwa ndi etodolac ndi ibuprofen
Etodolac ndi ibuprofen amalembedwa kuti athetse ululu. Amakonda kutengedwa kuti azichiza ululu wopweteka pang'ono mpaka pang'ono wamankhwala, mutu waching'alang'ala , kapena kupweteka kwa minofu (myalgia).
Etodolac ndi ibuprofen ndi othandiza kwambiri ndipo FDA imavomereza kuchiza ululu ndi kutupa kwa nyamakazi ya nyamakazi ndi nyamakazi ya nyamakazi. Mphamvu zamphamvu nthawi zambiri zimafunikira kuti athane ndi ululu wophatikizana kwambiri kapena kupweteka kwa mafupa komwe kumakhudzana ndi nyamakazi. Nthawi zina, ana opitilira zaka zakubadwa atha kuthandizidwanso ndi ma NSAID awa nyamakazi ya nyamakazi ya idiopathic .
Ibuprofen yowonjezerapo amalembedwa kuti azichiza malungo ndi kusamba kwa msambo (dysmenorrhea yoyamba). Mtundu wojambulidwa wa ibuprofen wotchedwa NeoProfen umagwiritsidwa ntchito pochizira patent ductus arteriosus (PDA), mtundu wa vuto la mtima, m'makanda asanakwane.
| Mkhalidwe | Etodolac | Zamgululi |
| Ululu | Inde | Inde |
| Nyamakazi | Inde | Inde |
| Matenda a nyamakazi | Inde | Inde |
| Matenda a achinyamata a nyamakazi | Inde | Inde |
| Malungo | Ayi | Inde |
| Matenda oyambira m'mimba | Ayi | Inde |
| Maluso a patent ductus arteriosus | Ayi | Inde |
Kodi etodolac kapena ibuprofen ndi yothandiza kwambiri?
Onse etodolac ndi ibuprofen ndi ma NSAID othandiza othandizira kupweteka. Zonsezi zimatseka michere ya cyclooxygenase (COX) yothetsera kutupa ndikuchepetsa kupweteka kwa omwe ali ndi nyamakazi. Komabe, zotsatira za etodolac zimatenga nthawi yayitali. Chifukwa chake, anthu ena atha kusankha etodolac chifukwa chotsika kwambiri pafupipafupi.
Phunziro la khungu kawiri kuyerekeza etodolac ndi ibuprofen , Odwala 1,446 omwe ali ndi nyamakazi amapatsidwa 150 mg ya etodolac kawiri tsiku lililonse, 500 mg ya etodolac kawiri tsiku lililonse, kapena 600 mg wa ibuprofen kanayi tsiku lililonse. Miyezo yonse iwiri ya etodolac imapezeka yofanana mofananira ndi mlingo wa ibuprofen. Pazotsatira zoyipa, omwe amatenga etodolac samadzimbidwa, kuphulika, komanso kutuluka magazi m'mimba kuposa omwe amatenga ibuprofen. Komabe, izi zitha kukhala zokhudzana ndi kuchuluka kwa omwe amapatsidwa mankhwala osokoneza bongo.
Ngakhale palibe mayesero ena azachipatala omwe afananapo ndi etodolac ndi ibuprofen, maphunziro osiyanasiyana afanizira ma NSAID ena ndi etodolac kapena ibuprofen. Kafukufuku wina adapeza kuti fayilo ya Pazipita tsiku mlingo wa diclofenac ndiwothandiza kwambiri kuposa kuchuluka kwa tsiku ndi tsiku kwa ibuprofen, naproxen, ndi celecoxib (koma mlingo wotsika kwambiri wa NSAID nthawi zonse umalimbikitsidwa). Kusanthula kwina kwa meta kunapeza kuti ma NSAID ena monga piroxicam ndi azapropazone ali pachiwopsezo chachikulu chakupha pomwe ibuprofen yocheperako imakhala ndi chiopsezo chochepa cha poizoni. Ponseponse, titha kunena kuti ma NSAID amakonda kukhala osiyana mosatekeseka m'malo mochita bwino.
Chifukwa cha mitundu ingapo yosankha zowawa, ndikofunikira kufunsa wothandizira zaumoyo kuti akuthandizireni chithandizo chamankhwala chabwino. Dokotala kapena wothandizira zaumoyo amatha kupereka upangiri woyenera wa zamankhwala pazamankhwala ena.
Kuphunzira ndi kuyerekezera mtengo wa etodolac vs. ibuprofen
Mapiritsi a generic etodolac nthawi zambiri amakhala ndi Medicare ndi mapulani a inshuwaransi. Ngati muli ndi matenda monga nyamakazi, mapulani a inshuwaransi amatha kuphimba etodolac zowawa. Mtengo wapakati wamalonda wa etodolac umasiyana pamlingo, koma mutha kulipira $ 50 ya etodolac pogwiritsa ntchito coupon ya SingleCare kuma pharmacies omwe akutenga nawo mbali.
Popeza ibuprofen imapezeka pa-counter, mitundu ina siyingakhale ndi mapulani a inshuwaransi. Komabe, ambiri mwa Medicare Part D ndi mapulani a inshuwaransi amayenera kulemba mapiritsi a mphamvu ya ibuprofen malinga ndi mtundu wa mankhwala. Mwambiri, ibuprofen ndi yotsika mtengo kuposa etodolac. Gwiritsani ntchito coupon ya SingleCare ya ibuprofen ngati muli ndi mankhwala ochokera kwa omwe amakupatsani chithandizo chamankhwala.
| Etodolac | Zamgululi | |
| Nthawi zambiri amakhala ndi inshuwaransi? | Inde | Inde (mapiritsi a mphamvu ya mankhwala) |
| Nthawi zambiri amakhala ndi Medicare Part D? | Inde | Inde |
| Mlingo woyenera | 300 mg 2 mpaka 3 tsiku lililonse | 400 mpaka 800 mg 3 mpaka 4 tsiku lililonse |
| Wopanga Medicare wamba | $ 0 mpaka $ 76 | $ 0– $ 22 |
| Mtengo wosakwatiwa | $ 40- $ 80 | $ 4– $ 24 |
Zotsatira zoyipa za etodolac vs. ibuprofen
Zotsatira zoyipa kwambiri za NSAIDs, kuphatikiza etodolac ndi ibuprofen, ndi nseru, kudzimbidwa (dyspepsia), kudzimbidwa, kutsekula m'mimba, komanso kupweteka m'mimba kapena m'mimba. Zina kupatula zovuta zam'mimba, ma NSAID amathanso kuyambitsa chizungulire, kutupa m'manja kapena m'miyendo (edema), kupweteka mutu, kuthamanga, ndi kulira m'makutu (tinnitus). Zotsatira zoyipa zambiri za etodolac ndi ibuprofen ndizofatsa ndipo zimatha zokha.
Zotsatira zoyipa za ma NSAID atha kuphatikizira zovuta zina, monga zotupa zazikulu kapena anaphylaxis, kuchokera kuzinthu zosagwira kapena zopanda ntchito. Zotsatira zoyipa zina zimaphatikizira m'mimba zoyipa monga kutuluka magazi m'mimba ndi zilonda zam'mimba . Funsani wothandizira zaumoyo wanu ngati muli ndi magazi pachitetezo, kuwonda, kapena kupweteka m'mimba.
| Etodolac | Zamgululi | |||
| Zotsatira zoyipa | Zoyenera? | Pafupipafupi | Zoyenera? | Pafupipafupi |
| Nseru | Inde | 1% -10% | Inde | 1% –3% |
| Kupweteka m'mimba | Inde | 1% -10% | Inde | 1% –3% |
| Kudzimbidwa | Inde | 1% -10% | Inde | 1% –3% |
| Kudzimbidwa | Inde | 1% -10% | Inde | 1% –3% |
| Kutsekula m'mimba | Inde | 1% -10% | Inde | 1% –3% |
| Chizungulire | Inde | 1% -10% | Inde | 1% –3% |
| Edema | Inde | 1% -10% | Inde | 1% –3% |
| Mutu | Inde | 1% -10% | Inde | 1% –3% |
| Kutupa | Inde | 1% -10% | Inde | 1% –3% |
| Tinnitus | Inde | 1% -10% | Inde | 1% –3% |
Izi sizingakhale mndandanda wathunthu wazovuta zomwe zingachitike. Chonde onani dokotala wanu kapena wothandizira zaumoyo kuti mudziwe zambiri.
Gwero: DailyMed ( Etodolac ), Tsiku Lililonse ( Zamgululi )
Kuyanjana kwa mankhwala a etodolac vs. ibuprofen
Chifukwa amaletsa enzyme ya COX-1, yomwe imathandizira kupanga ma platelet ndi kuundana kwamagazi, ma NSAID amatha kusokoneza zotsatira za omwe amawonda magazi. Ma NSAID atha kuwonjezera ngozi yakutuluka magazi kuchokera kwa antiplatelet agents monga aspirin ndi ma anticoagulants ngati warfarin.
Etodolac ndi ibuprofen zimatha kupangitsa kuti thupi lizisunga zamadzimadzi ndikukhudza impso. Zotsatira zake, ma NSAID awa amatha kuwonjezera kuthamanga kwa magazi. Ngati mukumwanso mankhwala a kuthamanga kwa magazi (antihypertensive), monga lisinopril kapena losartan, magazi anu angafunike kuyang'aniridwa mukamamwa NSAID.
Etodolac ndi ibuprofen zimatha kukhudza momwe cyclosporine, digoxin, kapena methotrexate zimachotsedwa mthupi. Kutenga NSAID kumatha kubweretsa chiopsezo chowonjezeka cha cyclosporine, digoxin, kapena methotrexate kawopsedwe.
Pezani zovuta zina zomwe zingachitike pansipa.
| Mankhwala osokoneza bongo | Gulu la mankhwala osokoneza bongo | Etodolac | Zamgululi |
| Asipilini | Chotupa | Inde | Inde |
| Warfarin | Wotsutsa | Inde | Inde |
| Lisinopril Wolemba Ramipril | Angiotensin-otembenuza enzyme (ACE) inhibitor | Inde | Inde |
| Losartan Zamgululi Olmesartan | Angiotensin receptor blocker (ARB) | Inde | Inde |
| Furosemide Hydrochlorothiazide | Odzetsa | Inde | Inde |
| Lifiyamu | Kusintha kwanyengo | Inde | Inde |
| Methotrexate Kuthamangitsidwa | Antimetabolite | Inde | Inde |
| Cyclosporine | Chitetezo chamthupi | Inde | Inde |
| Digoxin | Mtima glycoside | Inde | Inde |
Funsani katswiri wa zamankhwala pazinthu zina zomwe zingagwiritsidwe ntchito ndi mankhwala.
Machenjezo a etodolac ndi ibuprofen
Etodolac ndi ibuprofen, monga ma NSAID ena, atha kukulitsa chiopsezo cha zovuta zamatenda amtima monga kupwetekedwa mtima ndi stroke. Kugwiritsa ntchito NSAID kuyenera kupewedwa kapena kuyang'aniridwa mwa anthu omwe ali ndi mavuto amtima monga kulephera kwa mtima, matenda amtima, komanso kuthamanga kwa magazi.
Kugwiritsiridwa ntchito kwa etodolac kapena ibuprofen kumatha kubweretsa chiopsezo chowopsa cha zovuta zam'mimba (GI), monga kutuluka magazi m'mimba ndi zilonda zam'mimba. Popanda chithandizo choyenera, kutupa, ndi kutuluka m'magazi a GI zitha kupha. Okalamba atha kukhala pachiwopsezo chachikulu cha zovuta zoyipa za GI.
Ma NSAID sayenera kugwiritsidwa ntchito koyambirira kapena pambuyo poti mtima uchitike Mitsempha yamitsempha yodutsa mitanda yodutsa (CABG) opaleshoni .
Omwe ali ndi matenda a impso atha kukhala pachiwopsezo chowonjezeka cha mavuto aminso impso akamamwa ma NSAID.
Funsani wothandizira zaumoyo wanu kuti azisamala musanatenge NSAID.
Mafunso omwe amafunsidwa pafupipafupi okhudza etodolac vs. ibuprofen
Kodi etodolac ndi chiyani?
Etodolac ndi mankhwala osagwiritsidwa ntchito poletsa kutupa (NSAID) omwe amagwiritsidwa ntchito pochiza ululu ndi kutupa. Ndi FDA yovomerezedwa kuchiza nyamakazi ya nyamakazi ndi nyamakazi mwa akuluakulu. Generic etodolac imatha kupezeka ndi mankhwala.
Kodi ibuprofen ndi chiyani?
Ibuprofen amadziwika ndi mayina monga Advil ndi Motrin. Amapezeka pa-counter kuti azitha kupweteka pang'ono, kutentha thupi, komanso kupweteka kwa msambo. Ibuprofen yamphamvu kwambiri imatha kupezeka ndi mankhwala ochizira ululu ndi kutupa kwa nyamakazi ya nyamakazi ndi nyamakazi.
Kodi etodolac ndi ibuprofen ndizofanana?
Etodolac ndi ibuprofen sizofanana. Ngakhale onse ndi ma NSAID, ali ndi magwiridwe antchito ndi momwe amagwiritsidwira ntchito. Etodolac ndi mankhwala omwe amagwiritsidwa ntchito makamaka kwa akulu omwe ali ndi nyamakazi. Ibuprofen imapezeka mosavuta ngati mankhwala osokoneza bongo owawa ululu ndi malungo.
Kodi etodolac kapena ibuprofen ndibwino?
NSAID yabwinoko imadalira mulingo womwe mumatenga komanso zomwe mumalandira. Poyerekeza ndi ibuprofen, etodolac imatenga nthawi yayitali mthupi, chifukwa chake imatha kumwedwa kangapo tsiku lonse. Komabe, itha kukhala yotsika mtengo kuposa ibuprofen. Malingana ndi momwe mulili, dokotala wanu angakulimbikitseni wina ndi mnzake.
Kodi nditha kugwiritsa ntchito etodolac kapena ibuprofen ndili ndi pakati?
Etodolac ndi ibuprofen samalimbikitsidwa nthawi yapakati. Kugwiritsiridwa ntchito kwa NSAID panthawi yoyembekezera kumakhudzana ndi chiopsezo chowonjezeka cha zolepheretsa kubadwa kapena kupita padera, makamaka panthawi yomwe ali ndi pakati. Funsani wothandizira zaumoyo wanu ngati mukuganiza chithandizo chamankhwala ali ndi pakati .
Kodi ndingagwiritse ntchito etodolac kapena ibuprofen ndi mowa?
Kumwa mowa pang'ono kungakhale bwino nthawi zina mukatenga NSAID. Komabe, kumwa mowa mopitirira muyeso kumatha kubweretsa chiopsezo chowonjezeka cham'mimba ndi ma NSAID. Mowa ndi ma NSAID imatha kukwiyitsa m'mimba komanso m'matumbo, zomwe zingayambitse zilonda kapena kutuluka magazi.
Kodi etodolac ndi wakupha opweteka?
Etodolac ndiwopweteka kwambiri. Ndiwothandiza kwambiri pochiza ululu ndi kutupa komwe kumayambitsidwa ndi nyamakazi. Zimathandizanso pochiza ululu pambuyo pa njira zina monga opaleshoni yamano.
Kodi etodolac ndi yamphamvu kuposa naproxen?
Kuchita bwino kwa ma NSAID kumadalira kuchuluka kwa mankhwala omwe atengedwa, mwazinthu zina. Zinthu zonse kukhala zofanana, etodolac ndi naproxen ndizofanana mofananira. Malinga ndi kafukufuku wakhungu kawiri, etodolac ndi naproxen ali mofananamo zochizira nyamakazi. Mankhwala onsewa amavomerezanso bwino pokhudzana ndi zovuta zina.
