Levalbuterol vs. Albuterol: Kusiyana, kufanana, ndi zomwe zili zabwino kwa inu
Mankhwala osokoneza bongo Vs. MnzanuKuwunika kwa mankhwala osokoneza bongo & kusiyana kwakukulu | Zinthu zothandizira | Mphamvu | Kuphunzira inshuwaransi ndikufanizira mtengo | Zotsatira zoyipa | Kuyanjana kwa mankhwala | Machenjezo | FAQ
Levalbuterol ndi albuterol ndi mankhwala awiri omwe amagwiritsidwa ntchito pochiza bronchospasm yokhudzana ndi mphumu ndi matenda osokoneza bongo (COPD). Mphumu ndi matenda opuma omwe amakhudza anthu azaka zonse. Amadziwika ndi kupuma, kutsokomola, kupuma movutikira, ndi kukhwima pachifuwa. Akuyerekeza kuti mphumu imakhudza anthu pafupifupi 24 miliyoni ku United States, kuphatikiza ana 7 miliyoni.
COPD , omwe nthawi zina amatchedwa emphysema, ali ndi mawonekedwe ofanana ndi mphumu, komanso amaphatikizira kupanga ntchofu zazikulu panjira yapaulendo. Zomwe zimayambitsa matenda a mphumu sizidziwika, koma odwala ambiri omwe amakhala ndi COPD amakhala ndi mbiri yosuta fodya kapena kuwonetsedwa kwakanthawi m'mapapo.
Bronchospasm imalongosola njira yomwe imachitika mu mphumu ndi COPD pomwe ndege zimagwirizana, zomwe zimapangitsa kuti zikhale zovuta kudutsa mpweya. Izi nthawi zina zimatchedwa bronchoconstriction. Levalbuterol ndi albuterol onse amachiza bronchospasm, koma amagwira ntchito mosiyana.
Kodi pali kusiyana kotani pakati pa Levalbuterol ndi Albuterol?
Levalbuterol ndi mankhwala akuchipatala omwe amasankha pang'ono-beta-2-receptor agonist (SABA). Levalbuterol ndiye R-enantiomer wokangalika wa chisakanizo cha mtundu wa albuterol. Levalbuterol imalimbikitsa zolandilira za beta zomwe zimapangitsa kuti kupumula kwa minofu yolimba ya tronal ndi tracheal komanso njira yowonekera kwambiri. Levalbuterol imapezeka ngati metered-dose inhaler (MDI) yopereka 45 mcg dose pa actuation. Ikupezekanso ngati yankho logwiritsidwa ntchito pamakina a nebulizer. Njira yothetsera nebulizer imapezeka m'magulu a 0.31 mg / 3 ml, 0.63 mg / 3 ml, ndi 1.25 mg / 3ml.
Albuterol ndi mankhwala akuchipatala omwe amasankhanso pang'ono-beta-2-receptor agonist (SABA). Albuterol ndi mtundu wosakanikirana wama R-enantiomers ndi S-enantiomers wokhala ndi R-enantiomer pokhala isomer yogwira ntchito komanso yogwiritsira ntchito levalbuterol. Racemic albuterol imapezeka m'mapiritsi amkamwa mwamphamvu pakumasula 2 mg ndi 4 mg ndikutulutsa 4 mg ndi 8 mg. Albuterol imapezekanso poyankha pakamwa mu 2 mg / 5 ml. Albuterol imabweranso mu inhaler-inhaler inhaler yotulutsa 90 mcg pa actuation komanso njira zosiyanasiyana za nebulizer.
| Kusiyana kwakukulu pakati pa Levalbuterol ndi Albuterol | ||
|---|---|---|
| Levalbuterol | Khalid | |
| Gulu la mankhwala osokoneza bongo | Kusankha bwino beta-2-agonist | Kusankha bwino beta-2-agonist |
| Chizindikiro cha Brand / generic | Zolemba ndi generic zilipo | Zolemba ndi generic zilipo |
| Kodi dzina lake ndi ndani? | Xopenex | ProAir, Proventil, Ventolin, Accuneb, Vospire |
| Kodi mankhwalawa amabwera mwa mawonekedwe ati? | Meter-inhaler inhaler, yankho la nebulizer | Mitha-inhaler inhaler, nebulizer solution, mapiritsi amlomo, njira yamlomo |
| Kodi mulingo woyenera ndi uti? | 0.63 mg kudzera pa nebulizer kapena 45 mcg kudzera pa MDI maola onse 4-6 | 2.5 mg kudzera pa nebulizer kapena 90 mcg kudzera pa MDI maola onse 4-6 |
| Kodi mankhwalawa amatenga nthawi yayitali bwanji? | Zosasintha, zazifupi | Zosasintha, zazifupi |
| Ndani amagwiritsa ntchito mankhwalawa? | Ana azaka 4 zakubadwa kapena kupitilira, akulu | Makanda, ana, akulu |
Zomwe amathandizidwa ndi Levalbuterol ndi Albuterol
Levalbuterol ndi albuterol onse amagwira ntchito polimbikitsa ma beta receptors kuti atulutse minofu yosalala munjira zoyendetsera ndege, potero amalola kuti maulendowa atseguke ndikunyamula mpweya wopitilira m'mapapu osalimbana nawo pang'ono.
Onse a levalbuterol ndi albuterol ndi ovomerezeka ndi FDA pochiza kuphulika kwa mphumu, ma bronchospasms osakhalitsa kapena kupuma, komanso bronchospasm yokhudzana ndi COPD. Ndikofunikira kudziwa kuti palibe mankhwala omwe amavomerezedwa ngati prophylaxis, kapena kupewa, pazizindikirozi. Komabe, albuterol imavomerezedwa kuti igwiritsidwe ntchito mu prophylaxis ya bronchospasm yochita zolimbitsa thupi. Nthawi zambiri, albuterol imaperekedwa kwa mphindi 15 isanakwane zolimbitsa thupi kuti muchepetse mwayi wa bronchospasm woyambitsidwa ndi masewera olimbitsa thupi. Levalbuterol nthawi zina imagwiritsidwa ntchito ngati chizindikiro paziwonetserozi. Kutulutsa chizindikiro kumatanthauza kuti mankhwalawa sanalandiridwe kuti agwiritsidwe ntchito poyerekeza ndi Food and Drug Administration (FDA).
Tchati chotsatirachi chimagwiritsa ntchito mankhwalawa. Ndi omwe amakupatsani chithandizo chamankhwala okha omwe angadziwe ngati mankhwalawa ndi oyenera matenda anu. Mukakhala ndi mphumu yoopsa ndi COPD bronchospasm, chonde pitani kuchipatala ku dipatimenti yapafupi yoopsa.
| Mkhalidwe | Levalbuterol | Khalid |
| Kukula kwa mphumu | Inde | Inde |
| Bronchospasm yaposachedwa / episodic wheezing | Inde | Inde |
| Kuchita masewera olimbitsa thupi opangidwa ndi bronchospasm prophylaxis | Kutumiza | Inde |
| COPD bronchospasm yokhudzana | Inde | Inde |
| Chithandizo chamankhwala cha hyperkalemia | Kutumiza | Kutumiza |
| Chithandizo chothandizirana ndi matenda opumira a khanda | Ayi | Kutumiza |
Kodi Levalbuterol kapena Albuterol ndiyothandiza kwambiri?
Levalbuterol ndi albuterol amafanizidwa kwambiri pokhudzana ndi zotsatira za mphumu ndi COPD. 2015 kuphunzira adawunika achikulire omwe adagonekedwa mchipatala ali ndi mphumu kapena kuwonjezeka kwa COPD omwe amathandizidwa ndi levalbuterol kapena albuterol yoyendetsedwa ndi nebulization. Zotsatira zoyeserera zachipatalazi zidapeza kuti zotsatira zamankhwala zinali zofanana pakati pa mankhwala awiriwo ndipo onse anali othandiza kuthana ndi matenda a bronchospasm. Komabe, mtengo wa mankhwala a levalbuterol unali wokwera mtengo kwambiri kuposa mtengo wa mankhwala a albuterol, ndipo odwala omwe anali mgulu la levalbuterol anali mchipatala chotalikirapo kuposa odwala omwe ali mgulu la albuterol. Kukhala m'zipatala kwanthawi yayitali kumakulitsanso mtengo wogwirira ntchito.
KU kusanthula meta ndikuwunika mwatsatanetsatane mwa mayesero asanu ndi awiri, kuphatikiza odwala 1,600, adachitika poyerekeza levalbuterol ndi albuterol mu chifuwa chachikulu. Kafukufukuyu sanapeze kusiyana kwakukulu pakati pa mankhwalawa poyerekeza zotsatira zamankhwala monga kupuma, mpweya wokwanira, komanso kusintha kwamapapu. Mavuto am'mapapo nthawi zina amatchedwa kuchuluka kokakamiza, kapena FEV1, m'mabuku azachipatala. Kafukufukuyu adatsimikiza kuti kunalibe umboni wotsimikizira kusankha levalbuterol kuposa albuterol pochiza mphumu.
Ngakhale mankhwala onsewa ndi othandiza, omwe akukulemberani mavutowa atha kuyerekezera zakusowa kwa umboni wa levalbuterol komanso mtengo wake posankha mankhwala oti mupereke. Levalbuterol imavomerezedwa kokha kwa odwala azaka zinayi kapena kupitilira apo, chifukwa chake albuterol imakondedwa ndi ana ocheperako. Ndi dokotala wanu yekha amene angasankhe mankhwala oyenera a matenda anu.
Pezani coupon ya mankhwala
Kuphatikiza ndi kuyerekezera mtengo kwa Levalbuterol vs. Albuterol
Levalbuterol ndi mankhwala omwe amapatsidwa ndi inshuwaransi yamalonda. Zitha kupangidwa ndi dongosolo la Medicare Part D kapena Gawo B kutengera matenda. Popanda kufotokozera, levalbuterol itha kukuwonongerani ndalama zoposa $ 170. Coupon ya SingleCare ya Levalbuterol generic imatha kutsitsa mtengo mpaka $ 30 kuma pharmacies omwe akutenga nawo mbali.
Albuterol ikhoza kuphimbidwa ndi dongosolo la Medicare Part D kapena Gawo B kutengera matenda. Imakumananso ndi mapulani a inshuwaransi yamalonda. Albuterol itha kukhala $ 40 osaphimbidwa, koma ndi coupon yochokera ku SingleCare, mutha kupeza fomu yopangira zosakwana $ 10 kuma pharmacies omwe akutenga nawo mbali.
| Levalbuterol | Khalid | |
| Nthawi zambiri amakhala ndi inshuwaransi? | Inde | Inde |
| Nthawi zambiri amakhala ndi Medicare Part D? | Zimadalira matenda | Zimadalira matenda |
| Mlingo woyenera | 25, 0.63 mg / 3 ml | 25, 2.5 mg / 3 ml |
| Wopanga Medicare wamba | Zimatengera pulani | Zimatengera pulani |
| Mtengo wosakwatiwa | $ 30- $ 130 | $ 10- $ 20 |
Zotsatira zoyipa za Levalbuterol vs. Albuterol
Ngakhale levalbuterol ndi albuterol amasankha moyenera ma beta receptors pamiyendo yosalala yapaulendo, pakhoza kukhala zolimbikitsanso zamtima za beta-receptor zomwe zimayambitsa kuchuluka kwa kugunda kwa mtima, kotchedwa tachycardia. Onse a levalbuterol ndi albuterol atha kuyambitsa mantha komanso kunjenjemera. Migraine ndi chizungulire adadziwika ndi levalbuterol, koma osati albuterol.
Izi sizitanthauza kuti pakhale mndandanda wazovuta zomwe zingachitike. Chonde funsani omwe akukuthandizani kuti mupeze mndandanda wathunthu wazovuta.
| Levalbuterol | Khalid | |||
| Zotsatira zoyipa | Zoyenera? | Pafupipafupi | Zoyenera? | Pafupipafupi |
| Tachycardia | Inde | 2.7% | Inde | 2.7% |
| Migraine | Inde | 2.7% | Ayi | n / A |
| Dyspepsia | Inde | 2.7% | Inde | 1.4% |
| Kukokana kwamiyendo | Inde | 2.7% | Inde | 1.4% |
| Chizungulire | Inde | 2.7% | Ayi | n / A |
| Matenda oopsa | Ayi | n / A | Inde | 2.7% |
| Mantha | Inde | 9.6% | Inde | 8.1% |
| Kugwedezeka | Inde | 6.8% | Inde | 2.7% |
| Kuda nkhawa | Inde | 2.7% | Ayi | n / A |
| Kuchuluka kwa chifuwa | Inde | 4.1% | Inde | 2.7% |
| Matenda a kachilombo | Inde | 12.3% | Inde | 12.2% |
| Rhinitis | Inde | 2.7% | Inde | 6.8% |
| Sinusitis | Inde | 1.4% | Inde | 2.4% |
| Edema ya Turbinate | Inde | 1.4% | Ayi | n / A |
Gwero: Levalbuterol ( Tsiku ndi Tsiku Albuterol (PA) Tsiku ndi Tsiku )
Kuyanjana kwa mankhwala a Levalbuterol vs. Albuterol
Chifukwa cha kufanana kwawo kwamankhwala, zomwe zingagwiritsidwe ntchito ndi levalbuterol ndi albuterol ndizofanana. Azithromycin, mankhwala omwe amapezeka kwambiri m'matenda opuma, ayenera kupewedwa limodzi ndi levalbuterol kapena albuterol ngati zingatheke. Azithromycin, ikamayendetsedwa ndi ma beta-agonists achidule, imakhala ndi chiopsezo chowonjezera kutalikitsa kwa QT, mtundu wamtima wamtima. Ngati kuphatikiza uku kuyenera kugwiritsidwa ntchito, ntchito yamtima wodwala iyenera kuyang'aniridwa bwino. Ndikofunika kupeza maziko a ntchito yamtima musanapereke mankhwalawa nthawi yomweyo.
Ma Beta blockers, omwe nthawi zambiri amagwiritsidwa ntchito poletsa kugunda kwa mtima ndi kuthamanga kwa magazi, amagwira ntchito mosiyana ndi beta-agonists. Ntchito zawo zitha kutsutsana. Ngati wodwala akuyenera kukhala beta blocker komanso beta-agonist, kugwiritsa ntchito beta blocker yoyeserera. Zitsanzo za ma beta blockers osagwira mtima ndi monga atenolol ndi metoprolol, pakati pa ena.
Ili si mndandanda wathunthu wazomwe zingachitike mukamagwiritsa ntchito mankhwala osokoneza bongo. Chonde funsani upangiri wa zamankhwala kuti mumvetsetse bwino zamankhwala omwe angachitike.
| Mankhwala osokoneza bongo | Gulu la mankhwala osokoneza bongo | Levalbuterol | Khalid |
| Kafeini | Chotsatira cha Xanthine / CNS cholimbikitsa | Inde | Inde |
| Phenylephrine Pseudoephedrine | Odzichotsera | Inde | Inde |
| Acebutolol Atenolol Betaxolol Bisoprolol Chosema Zamgululi Nadolol Nebivolol Zamgululi Sotalol | Beta blockers (otsutsana ndi beta) | Inde | Inde |
| Amiodarone Dronedarone | Zotsutsa-zosokoneza | Inde | Inde |
| Amitriptyline Clomipramine Mzere wa Nortriptyline | Tricyclic antidepressants | Inde | Inde |
| Citalopram Kuyanjana Fluoxetine Sertraline | Kusankha serotonin reuptake inhibitors (SSRIs) | Inde | Inde |
| Azithromycin Clarithromycin | Maantibayotiki | Inde | Inde |
| Fluconazole Chinthaka Ketoconazole | Zosakaniza | Inde | Inde |
Machenjezo a Levalbuterol ndi Albuterol
Levalbuterol ndi albuterol zingayambitse bronchospasm yodzidzimutsa, mkhalidwe womwe bronchospasm ya wodwalayo kapena Wheeze imangokulirakulira m'malo mokhala bwino. Izi zikachitika, mankhwala ayenera kuyimitsidwa nthawi yomweyo ndikuyamba chithandizo chatsopano.
Kuwonongeka kwa mphumu kumatha kuchitika kwa maola, masiku, kapena kupitilira apo. Ngati wodwala asthmatic ayamba kufuna kuchuluka kwa bronchodilator kuti athetse matenda a mphumu, ichi chitha kukhala chisonyezo kuti kuwonongeka kukuchitika. Odwala omwe akukumana ndi izi angafunike mankhwala oletsa kutupa monga ma corticosteroids kapena kusintha kwa mankhwala osamalira.
Levalbuterol ndi albuterol, makamaka pamlingo wopitilira muyeso womwe ungavomerezedwe, imatha kuyambitsa mavuto amtima ndi mtima monga kuthamanga kwa mtima komanso kuthamanga kwa magazi. Nthawi zina zazikulu, kumangidwa kwamtima kwachitika. Musapitirire mlingo woyenera womwe dokotala wakupatsani.
Magawo a potaziyamu otsika, kapena hypokalemia, adawonedwa ndi levalbuterol ndi albuterol. Izi zitha kuyambitsidwa ndi kusuntha kwama cell. Ngakhale mankhwalawa nthawi zina amagwiritsidwa ntchito ngati zilembo kuti achepetse potaziyamu mwadala, zotsatirazi ziyenera kuyang'aniridwa.
Mafunso omwe amafunsidwa pafupipafupi za Levalbuterol vs. Albuterol
Levalbuterol ndi chiyani?
Levalbuterol ndi mankhwala omwe amamwa mankhwala omwe ndi achidule a beta-agonist, omwe amadziwikanso kuti bronchodilator. Amagwiritsidwa ntchito pochiza bronchospasm yokhudzana ndi mphumu ndi COPD. Amagwiritsidwanso ntchito polemba-chizindikiro kuti ateteze bronchospasm yochita zolimbitsa thupi. Amapezeka ngati mawonekedwe a metered-inhaler inhaler komanso mayankho omwe angagwiritsidwe ntchito mu nebulizer.
Kodi Albuterol ndi chiyani?
Albuterol imakhalanso ndi mankhwala omwe amalembedwa mwachidule ndi beta-agonist. Imadziwikanso kuti bronchodilator ndipo imagwiritsidwa ntchito pochiza bronchospasm yokhudzana ndi mphumu ndi COPD komanso kupewa bronchospasm yochita zolimbitsa thupi. Amapezeka m'njira zosiyanasiyana kuphatikiza mapiritsi am'kamwa, zothetsera pakamwa, mankhwala opumira ma metered, ndi mayankho omwe angagwiritsidwe ntchito mu nebulizer.
Kodi Levalbuterol ndi Albuterol ndi ofanana?
Levalbuterol ndi albuterol ndizofanana ndi mankhwala, koma sizofanana ndendende. Albuterol ndi mtundu wosakanikirana wamagulu awiri opangira enantiomers, R-albuterol ndi S-albuterol. Nthawi zina amatchedwa racemic albuterol. Levalbuterol ili ndi R-albuterol yokha, yomwe imagwira ntchito kwambiri pamankhwalawa.
Kodi Levalbuterol kapena Albuterol ndibwino?
Kuyerekeza kwakumbuyo maphunziro Zonse zasonyeza kuti levalbuterol ndi albuterol ali ndi zotsatira zofanana zachipatala. Olembera angaganizire za mtengo ngati womwe ungachitike komanso zotsatirapo zoyipa posankha wina ndi mnzake.
Kodi nditha kugwiritsa ntchito Levalbuterol kapena Albuterol ndili ndi pakati?
Levalbuterol ndi albuterol onse amawerengedwa kuti ali ndi pakati C ndi FDA. Izi zikutanthauza kuti palibe maphunziro azachipatala owonetsa chitetezo pathupi. Mankhwalawa ayenera kugwiritsidwa ntchito pokhapokha phindu litaposa chiwopsezo chake. Pakadali pano, albuterol itha kusankhidwa chifukwa chopezeka pazambiri zakale zakugwiritsa ntchito kwake pathupi.
Kodi ndingagwiritse ntchito Levalbuterol kapena Albuterol ndi mowa?
Palibe zotsutsana mwachindunji ndi albuterol ndi mowa. Komabe, mowa umatha kuchepetsa kupuma komanso kukhudza magwiridwe antchito am'mapapo, zomwe sizothandiza kuthana ndi bronchospasm.
Kodi Levalbuterol ndi yopulumutsa inhaler?
Inde, levalbuterol HFA ndi yopulumutsa inhaler yomwe imagwiritsidwa ntchito pochiza kuwonjezeka kwa mphumu kapena bronchospasms chifukwa cha COPD.
Kodi Levalbuterol ndi steroid?
Levalbuterol si steroid kapena anti-inflammatory ndipo sayenera kugwiritsidwa ntchito m'malo mwa steroid pomwe kugwiritsa ntchito steroid kukuwonetsedwa, monga kuphulika kwa mphumu.
Kodi Levalbuterol amatenga nthawi yayitali bwanji?
Pafupifupi, zotsatira za mankhwala amodzi a levalbuterol amatha maola asanu kapena asanu ndi limodzi. Levalbuterol imayamba kugwira ntchito pafupifupi mphindi 15 mutayang'anira.
