Lovastatin vs Atorvastatin: Kusiyanitsa Kwakukulu ndi Kufanana

Mankhwala osokoneza bongo Vs. Mnzanu

Lovastatin ndi atorvastatin ndi mankhwala achibadwa a statin omwe amachiza cholesterol. Mankhwala onsewa amadziwika kuti HMG-coA reductase inhibitors. Amagwira ntchito poletsa kutulutsa kwa cholesterol m'magazi. Mwa kutsitsa cholesterol cha LDL, zitha kuthandiza kupewa chiopsezo cha mtima ndi zilonda mwa iwo omwe ali ndi matenda amtima. Ngakhale amafanana, amakhalanso ndi zina zomwe zikambirana.

Lovastatin

Lovastatin ndi dzina loti Mevacor ndi Altoprev. Amalangizidwa kuti azichiza matenda a arteriosclerosis ndi hypercholesterolemia (cholesterol). Omwe ali ndi matenda amtima amathanso kuthandizidwa ndi lovastatin kuti muchepetse cholesterol komanso LDL yonse.

Lovastatin imapezeka ngati 10 mg, 20 mg, ndi 40 mg piritsi yamlomo. Altoprev ndi dzina lotulutsidwa lomwe limapezeka ngati 20 mg, 40 mg, kapena piritsi la 60 mg pakamwa. Lovastatin tikulimbikitsidwa kuti titenge ndi chakudya chamadzulo. Izi ndichifukwa cha kuchuluka kwa lovastatin ndi kudya. Omwe ali ndi vuto la impso angafunike kumwa mankhwala ochepa kuti apewe mavuto.

Atorvastatin

Atorvastatin ndi dzina loti Lipitor. Amagwiritsidwa ntchito kuchepetsa cholesterol ndi LDL cholesterol mwa anthu omwe ali ndi magazi ambiri. Amaperekedwanso kuti achepetse chiopsezo cha kufa ndi matenda amtima komanso kupwetekedwa mtima.

Atorvastatin imayendetsedwa ngati piritsi pakamwa mu mphamvu ya 10 mg, 20 mg, 40 mg, kapena 80 mg. Mosiyana ndi lovastatin, imatha kutengedwa nthawi iliyonse ya tsiku. Izi ndichifukwa cha theka la moyo wake. Komabe, sikoyenera kutengedwa ndi chakudya. Atorvastatin sakulimbikitsidwanso kwa iwo omwe ali ndi matenda owopsa a chiwindi.

Lovastatin vs Atorvastatin Mbali ndi Kuyerekeza Koyipa

Lovastatin ndi atorvastatin ndi mankhwala awiri opangira ma statin omwe amafanana kwambiri. Ngakhale amafanana m'njira zingapo, amakhalanso ndi kusiyana kwakukulu. Mankhwala onsewa akhoza kuwerengedwanso pansipa.

Lovastatin	Atorvastatin
Yotchulidwa Kwa
Cholesterol Yambiri Mkulu Triglycerides Kupewa Matenda a Mtima ndi zochitika zina zokhudzana nazo Matenda a Coronary arteriosclerosis Matenda achilengedwe Matenda a Atrial	Cholesterol Yambiri Mkulu Triglycerides Kupewa Matenda a Mtima ndi zochitika zina zokhudzana nazo Hyperlipoproteinemia Matenda a m'mimba
Gulu la Mankhwala
HMG CoA reductase inhibitors	HMG CoA reductase inhibitors
Wopanga
Zowonjezera	Zowonjezera
Zotsatira zoyipa
Kupweteka m'mimba Kudzimbidwa Ululu wophatikizana Mutu Kupweteka kwa minofu	Nasopharyngitis Kupweteka kwa minofu Ululu wophatikizana Kutsekula m'mimba Matenda a mkodzo Kupweteka m'mimba Ululu kumapeto
Kodi pali generic?
Lovastatin ndi dzina lodziwika bwino.	Atorvastatin ndi dzina lodziwika bwino.
Kodi imakhala ndi inshuwaransi?
Zimasiyanasiyana malinga ndi omwe amakupatsani	Zimasiyanasiyana malinga ndi omwe amakupatsani
Mafomu a Mlingo
Piritsi lapakamwa	Piritsi lapakamwa
Avereji ya Mtengo wa Cash
30 (pa mapiritsi 30)	519 (pa mapiritsi 30)
Mtengo Wotsatsa Wa singleCare
Mtengo wa Lovastatin	Mtengo wa Atorvastatin
Kuyanjana kwa Mankhwala Osokoneza bongo
CYP3A4 inhibitors (ketoconazole, itraconazole, posaconazole, voriconazole, erythromycin, clarithromycin, HIV protease inhibitors, telaprevir, nefazodone, boceprevir, etc.) Cyclosporine Protease inhibitors (tipranavir, ritonavir, saquinavir, fosamprenavir, nelfinavir) Amiodarone Colchicine Ranolazine Fenofibrate Gemfibrozil Niacin Diltiazem Zamgululi Dronedarone Kutumiza Madzi amphesa	CYP3A4 inhibitors (ketoconazole, itraconazole, posaconazole, voriconazole, erythromycin, clarithromycin, HIV protease inhibitors, telaprevir, nefazodone, boceprevir, etc.) Cyclosporine Protease inhibitors (tipranavir, ritonavir, saquinavir, fosamprenavir, nelfinavir) Fenofibrate Gemfibrozil Niacin Digoxin Diltiazem Njira zolera zapakamwa Rifampin Madzi amphesa
Kodi nditha kugwiritsa ntchito pokonzekera kutenga pakati, kutenga pakati, kapena kuyamwitsa?
Lovastatin ali mgulu la X ndipo amatha kupweteketsa mwana akagwiritsidwa ntchito kwa amayi apakati. Lovastatin sichivomerezeka kwa amayi apakati.	Atorvastatin ili m'gulu la Mimba X ndipo imatha kuvulaza mwana akagwidwa. Atorvastatin sichivomerezeka kwa amayi apakati.

Chidule

Lovastatin ndi atorvastatin ndi mankhwala othandiza oteteza cholesterol. Onsewa amagwiritsidwa ntchito popewa zovuta zamtima monga matenda amtima ndi sitiroko kwa odwala ena. Ngakhale mankhwala onsewa amagwira ntchito mofananamo, amakhalanso ndi magwiridwe antchito.

Potengera potency, kafukufuku wasonyeza kuti atorvastatin ndiyamphamvu kuposa lovastatin. Omwe amatenga atorvastatin amapezeka kuti akucheperachepera mu cholesterol cha LDL. Komabe, mankhwala onsewa ndi othandiza pochepetsa chiopsezo cha zochitika zokhudzana ndi matenda amtima.

Lovastatin nthawi zambiri amalimbikitsidwa kuti atenge usiku ndi chakudya chifukwa cha theka la moyo wake. Mbali inayi, atorvastatin imatha kutengedwa m'mawa kapena usiku.

Mankhwala onsewa amathandizidwa ndi mavitamini a CYP3A4 m'chiwindi. Pachifukwa ichi, amagawana zovuta zofananira komanso kulumikizana ndi mankhwala. Mwachitsanzo, sayenera kugwiritsidwa ntchito ndi mankhwala oletsa enzyme omwe angapangitse kuti pakhale zovuta.

Kugwiritsa ntchito lovastatin kapena atorvastatin kuyenera kukambirana ndi dokotala. Mankhwala onsewa sayenera kugwiritsidwa ntchito ali ndi pakati chifukwa chowoneka kuti ali pachiwopsezo cha fetus. Chifukwa cha chiwopsezo cha zotsatirapo zake komanso momwe amathandizira pakumwa mankhwala, ndikofunikira kuwunikanso mosamala mankhwala onse a statin.