Shingrix vs.Zostavax: Kusiyana, kufanana, ndi zomwe zili zabwino kwa inu
Mankhwala osokoneza bongo Vs. MnzanuKuwunika kwa mankhwala osokoneza bongo & kusiyana kwakukulu | Zinthu zothandizira | Mphamvu | Kuphunzira inshuwaransi ndi kufananiza mtengo | Zotsatira zoyipa | Kuyanjana kwa mankhwala | Machenjezo | FAQ
Pakalipano pali katemera awiri omwe angaperekedwe kuti ateteze herpes zoster, omwe amadziwika kuti shingles: Shingrix ndi Zostavax. Katemera wa shingles amalimbikitsidwa kwa akulu atakwanitsa zaka 50.
Anthu ambiri ali ndi kachilombo ka varicella zoster ngati adakhalapo ndi nthomba. Nkhuku ikatha, kachilombo ka varicella zoster kamagona m'thupi kwazaka zambiri, kapenanso mpaka kalekale. Pambuyo pake m'moyo, kachilomboka kakhoza kuyambiranso ngati kulumikizana ndikupangitsa zotupa zopweteka zomwe nthawi zambiri zimazungulira nkhope kapena thunthu.
Ngakhale Shingrix ndi Zostavax amagwira ntchito m'njira zofananira kuti asagwedezeke, pali kusiyana kofunikira pakati pa ziwirizi.
Kodi pali kusiyana kotani pakati pa Shingrix ndi Zostavax?
Shingrix (Shingrix ndi chiyani?) Ndi mankhwala ophatikizidwanso, osakanikirana ndi zoster omwe adavomerezedwa koyamba ndi FDA mu 2017. Amagwiritsa ntchito varicella-zoster glycoprotein E antigen kuti apange chitetezo chamthupi mthupi. Chothandizira, kapena chowonjezera chowonjezera, chimathandiza kulimbikitsa chitetezo cha mthupi ku kachilomboka. Chifukwa Shingrix ndi katemera wosagwira, amatha kugwiritsidwa ntchito kwa odwala omwe ali ndi chitetezo chokwanira kapena omwe ali ndi chitetezo chamthupi chofooka.
Shingrix imayendetsedwa ngati jekeseni mu mnofu (mnofu). Amapatsidwa magawo awiri osiyana ndi nthawi ya miyezi iwiri kapena isanu ndi umodzi pakati. Mlingo wachiwiri ndikofunikira kuti zitsimikizike kuti zitha kugwira ntchito nthawi yayitali.
Zostavax, yovomerezedwa mu 2006, ndi katemera wa herpes zoster wamoyo. Mwanjira ina, Zostavax imakhala ndi kachilombo kofooka kamene kamatulutsa chitetezo chamthupi. Pachifukwa ichi, sikulimbikitsidwa kwa iwo omwe ali ndi chitetezo chokwanira. Kapenanso, katemerayo atha kuyambitsa matenda.
Zostavax imayikidwa ngati jekeseni imodzi pansi pa khungu (subcutaneous). Ikubwera mu mtundu wachisanu ndi a mtundu wosakhazikika wa firiji . Mtundu wachisanu uyenera kusungidwa pakuzizira komanso posungitsa kuti zitsimikizike ngati zostavax yosungika mufiriji itha kusungidwa mufiriji mpaka itagwiritsidwa ntchito.
| Kusiyana kwakukulu pakati pa Shingrix ndi Zostavax | ||
|---|---|---|
| Shingrix | Zostavax | |
| Gulu la mankhwala osokoneza bongo | Katemera | Katemera |
| Chizindikiro cha Brand / generic | Dzina Brand yekha | Dzina Brand yekha |
| Kodi dzina lachibadwa ndi liti? | Zoster Vaccine Recombinant, Yothandiza | Katemera wa Zoster Live |
| Kodi mankhwalawa amabwera mwa mawonekedwe ati? | Kuyimitsidwa kwa jekeseni wamitsempha | Kuyimitsidwa kwa jakisoni wamagetsi |
| Kodi mulingo woyenera ndi uti? | Onetsetsani mlingo umodzi (0,5 ml) kenako mulingo wina (0,5 ml) pakati pa miyezi iwiri ndi 6 pambuyo pake | Yambitsani mlingo umodzi (0.65 ml) kamodzi |
| Kodi mankhwalawa amatenga nthawi yayitali bwanji? | Katemera amatha mu miyezi iwiri kapena isanu ndi umodzi mutalandira mankhwala awiri | Katemera amaliza pambuyo pa mlingo umodzi |
| Ndani amagwiritsa ntchito mankhwalawa? | Akuluakulu azaka 50 kapena kupitilira apo | Akuluakulu azaka 50 kapena kupitilira apo |
Zomwe amathandizidwa ndi Shingrix ndi Zostavax
Shingrix ndi Zostavax ndi FDA yovomerezedwa kupewa ma shingles (herpes zoster). Katemera onsewa akuwonetsedwa kuti amateteza kumankhwala kwa achikulire azaka 50 kapena kupitilira apo. Shingrix ndi Zostavax sagwiritsidwa ntchito popewa matenda a varicella, omwe amadziwika kuti nkhuku.
Postherpetic neuralgia ndi mtundu wodziwika wa ululu wamitsempha womwe umakhalapo ndi ma shingles. Chifukwa Shingrix ndi Zostavax amatha kupewa ma shingles, amathanso kupewa postherpetic neuralgia (PHN) ndi zovuta zina zopweteka. Komabe, katemerayu sanalembedwe kuti akuchiza PHN.
| Mkhalidwe | Shingrix | Zostavax |
| Kupewa kwa herpes zoster (ming'alu) | Inde | Inde |
Kodi Shingrix kapena Zostavax ndiyothandiza kwambiri?
Shingrix ndi Zostavax onse atsimikiziridwa kuti amateteza ma shingles. Komabe, Shingrix ndi katemera watsopano yemwe amaonedwa kuti ndiwothandiza kwambiri kuposa Zostavax. Shingrix imalimbikitsidwanso kwa iwo omwe adalandira kale katemera wa Zostavax m'mbuyomu.
Mayesero azachipatala awonetsa kuti Shingrix ndi 97% yothandiza poletsa ma shingles kwa akulu azaka zapakati pa 50 ndi 69. Shingrix imathandizanso kupewa ming'oma kwa achikulire-achikulire azaka zopitilira 70, Shingrix ali 91% yothandiza .
Zostavax ili ndi Mphamvu 70% mlingo wopewa kugwedezeka kwa achikulire azaka 50 mpaka 69, malinga ndi Zoster Efficacy and Safety Trial (ZEST). Zotsatira zochokera ku Phunziro la Kupewa kwa Shingles adawonetsa kuti Zostavax ndi 51% yothandiza polimbana ndi ma shingles. Poyerekeza ndi Shingrix, mphamvu ya Zostavax imachepa m'magulu okalamba. Kutengera zotsatira za SPS, Zostavax ndi 64% yothandiza kwa achikulire azaka 60 mpaka 69 zakubadwa; 41% yogwira mwa achikulire azaka zapakati pa 70 mpaka 79; ndi 18% yothandiza kwa akulu azaka 80 kapena kupitilira apo.
Wothandizira zaumoyo wanu angakulimbikitseni Shingrix pa Zostavax. Shingrix imalimbikitsidwa makamaka kwa odwala omwe ali ndi chitetezo chokwanira chifukwa ndi katemera wopanda moyo. Funsani dokotala wanu kapena wamankhwala za katemera wa shingles woyenera.
Kuphunzira ndi kuyerekezera mtengo wa Shingrix vs.Zostavax
Kwa achikulire azaka 50 kapena kupitilira apo, ndi mapulani okha ndi Medicare Part D kufalitsa idzafotokoza katemera wa Shingrix. Komabe, pangakhalebe copay ngakhale kufotokozedwa kwa Medicare Part D. Mtengo wapakati wa ndalama imodzi ya Shingrix ndi $ 167, ngakhale mutha kugwiritsa ntchito khadi yochotsera ndi mankhwala kuti muchepetse mtengo uwu. Funsani ku pharmacy kwanuko kuti muwone ngati mungagwiritse ntchito khadi ya Shingrix SingleCare.
Monga Shingrix, Zostavax imakonzedwa makamaka ndi mapulani a Medicare Part D kapena mapulani a Medicare Advantage okhala ndi kufotokozera kwa Medicare Part D. Copay ya Zostavax yokhala ndi inshuwaransi imatha kusiyanasiyana. Ndi mtengo wapakati wa $ 278, Zostavax ikhoza kukhala yokwera mtengo popanda kapena popanda inshuwaransi. Kugwiritsa ntchito khadi yochotsera ndi Zostavax kumatha kuchepetsa mtengo.
| Shingrix | Zostavax | |
| Nthawi zambiri amakhala ndi inshuwaransi? | Inde | Inde |
| Nthawi zambiri amakhala ndi Medicare Part D? | Inde | Inde |
| Mlingo woyenera | 1 jakisoni (0.5 ml) ndiyeno jakisoni wina (0.5 ml) miyezi 2 mpaka 6 pambuyo pake | 1 jekeseni wa mlingo umodzi (0.65 ml) |
| Wopanga Medicare wamba | $ 0- $ 164 | $ 0- $ 237 |
| Mtengo wosakwatiwa | $ 155 + | N / A |
Zotsatira zoyipa za Shingrix vs.Zostavax
Zotsatira zoyipa kwambiri za Shingrix ndi Zostavax zimakhudza zomwe zimachitika patsamba la jakisoni. Pambuyo pa jakisoni wa Shingrix kapena Zostavax, mutha kumva kupweteka, kufiira, kapena kutupa mozungulira tsamba la jakisoni. Muthanso kumva kuwawa kapena kuyabwa kuzungulira jekeseni.
Poyerekeza ndi Zostavax, Shingrix akuti amayambitsa machitidwe ena monga mutu, malungo, kupweteka kwa minofu (myalgia), ndi kutopa. Ngakhale zotsatirazi zitha kukhala zosokoneza, nthawi zambiri zimakhala zofatsa ndipo zimatha zokha.
| Shingrix | Zostavax | |||
| Zotsatira zoyipa | Zoyenera? | Pafupipafupi | Zoyenera? | Pafupipafupi |
| Kufiira pamalo obayira | Inde | 39% | Inde | 36% |
| Ululu pamalo obayira | Inde | 86% | Inde | 3. 4% |
| Kutupa pamalo obayira | Inde | 29% | Inde | 26% |
| Kuyabwa pamalo obayira | Inde | awiri% | Inde | 7% |
| Mutu | Inde | Zinayi. Asanu% | Inde | 1% |
| Malungo | Inde | 26% | Inde | awiri% |
| Kupweteka kwa minofu | Inde | 53% | Ayi | * |
| Kutopa | Inde | 51% | Ayi | * |
* sananene
Pafupipafupi sizidalira zomwe zimayesedwa pamutu. Izi sizingakhale mndandanda wathunthu wazovuta zomwe zingachitike. Chonde onani dokotala wanu kapena wothandizira zaumoyo kuti mudziwe zambiri.
Gwero DailyMed (Shingrix) , Tsiku ndi Tsiku (Zostavax)
Kuyanjana kwa mankhwala a Shingrix vs.Zostavax
Mankhwala osokoneza bongo monga cyclosporine ndi tacrolimus amatha kuchepetsa mphamvu ya katemera. Steroids, monga prednisone, ndi chemotherapy amathanso kukhala ndi zovuta zoteteza thupi zomwe zingasinthe momwe katemera amagwirira ntchito.
Omwe ali ndi chithandizo chamankhwala osokoneza bongo ayenera kupewa Zostavax palimodzi; Zostavax ili ndi kachilombo koyambitsa matenda, kamene kangayambitse matenda.
Mankhwala osokoneza bongo monga acyclovir ndi famciclovir amatha kusokoneza zotsatira za katemera wa Zostavax. Advisory Committee on Immunization Practices (ACIP) ikulimbikitsa kuti anthu omwe ali ndi mankhwala ochepetsa mphamvu ya ma virus sayenera kumwa mankhwala ochepetsa mphamvu Maola 24 kale kupeza katemera wa Zostavax. Chithandizo ndi mavairasi oyambitsa sayenera kuyambiranso kwa masiku osachepera 14 mutalandira katemera wa Zostavax.
| Mankhwala osokoneza bongo | Gulu la Mankhwala | Shingrix | Zostavax |
| Cyclosporine Tacrolimus Prednisone Chemotherapy | Njira zochizira matenda | Inde | Inde |
| Acyclovir Valacyclovir Famciclovir | Maantivayirasi | Ayi | Inde |
Funsani katswiri wa zamankhwala pazinthu zina zomwe zingagwiritsidwe ntchito ndi mankhwala
Machenjezo a Shingrix ndi Zostavax
Shingrix ndi Zostavax zimatha kuyambitsa vuto la hypersensitivity, kapena matupi awo sagwirizana ndi omwe ali ndi chifuwa chodzipangira katemera. Zostavax imatha kuyambitsa mavuto ena mwa omwe ali ndi ziwengo ku gelatin kapena neomycin. Kulimbana ndi zovuta zina kumatha kubweretsa kupsa mtima komanso kupuma movutikira (anaphylaxis).
Zostavax iyenera kupewedwa mwa iwo omwe amatenga ma immunosuppressive agents komanso omwe akukhudzidwa ndimatenda omwe amachepetsa chitetezo chamthupi.
Funsani dokotala wanu kapena wamankhwala za zodzitetezera zina musanalandire katemera wa shingles.
Mafunso omwe amafunsidwa pafupipafupi za Shingrix vs. Zostavax
Shingrix ndi chiyani?
Shingrix ndi Katemera wophatikizidwanso ankapewa herpes zoster, kapena ma shingles, mwa akulu azaka 50 kapena kupitilira apo. Ovomerezeka mu 2017, Shingrix ndi katemera wosagwira omwe mulibe varicella-zoster virus. Amapatsidwa mankhwala awiri ndi miyezi iwiri kapena isanu ndi umodzi pakati pa mlingo woyamba ndi wachiwiri. Shingrix amapangidwa ndi GlaxoSmithKline.
Kodi Zostavax ndi chiyani?
Zostavax ndi katemera wa zoster wamoyo yemwe FDA idavomerezedwa mu 2006. Monga katemera wokhazikika, Zostavax ili ndi mtundu wofooka wa varicella-zoster virus. Zostavax imayendetsedwa kamodzi kokha kwa akulu azaka 50 kapena kupitilira apo. Amapangidwa ndi Merck.
Kodi Shingrix ndi Zostavax ndi ofanana?
Onse Shingrix ndi Zostavax amatha kuchepetsa ngozi ya ma shingles. Komabe, zimasiyana pakukwaniritsa, kuwongolera, ndi zotsatirapo zake. Shingrix ndi mankhwala ophatikiziranso zoster ndipo Zostavax ndi katemera wamoyo. Kutanthauza kuti, Shingrix ili ndi mtundu wosagwira ntchito wa varicella zoster virus ndipo Zostavax ili ndi mtundu wamoyo, wofooka wa virus. Kusiyananso kwina ndikuti Shingrix amalowetsedwa mu mnofu pomwe Zostavax imayikidwa pansi pa khungu. Poyerekeza ndi Zostavax, Shingrix ndi katemera wa shingles watsopano.
Kodi Shingrix kapena Zostavax ndibwino?
Shingrix ndi yothandiza kwambiri kuposa Zostavax. Shingrix ndi 97% yothandiza popewera ma shingles kwa achikulire azaka 50 mpaka 69 pomwe Zostavax ndi 70% yokha yothandiza kupewa ma shingles amsinkhu womwewo. Shingrix nthawi zonse imalepheretsa kulumikizana kwa achikulire pomwe mphamvu ya Zostavax imachepa ndikukula. Komabe, Shingrix imakhala ndi zoyipa zambiri kuposa Zostavax.
Kodi nditha kugwiritsa ntchito Shingrix kapena Zostavax ndili ndi pakati?
Centers for Disease Control and Prevention (CDC) silimbikitsa Shingrix kapena Zostavax mwa amayi omwe ali ndi pakati. Palibe maphunziro okwanira kuti adziwe fayilo ya chitetezo cha Shingrix kapena Zostavax mwa amayi apakati . Funsani dokotala wanu kapena wothandizira zaumoyo musanalandire katemera wa shingles.
Kodi ndingagwiritse ntchito Shingrix kapena Zostavax ndi mowa?
Kumwa mowa sikusintha mphamvu ya Shingrix kapena Zostavax. Ndibwino kumwa mosapitirira malire mukalandira katemera wa katemera wa shingles.
Katemera wa Shingrix amatenga nthawi yayitali bwanji?
Mayesero azachipatala awonetsa kuti Shingrix imakhala yogwira ntchito kwa zaka zosachepera zinayi pambuyo mlingo wachiwiri. Akuti Shingrix amatenga nthawi yayitali kuposa pamenepo. Komabe, maphunziro ena akuchitidwa pakuthandizira kwa Shingrix kwakanthawi.
Kodi Zostavax imagwira ntchito nthawi yayitali bwanji?
Chitetezo ku zikopa chimakhala chozungulira zaka zisanu mutalandira katemera ndi Zostavax . Pambuyo pa zaka zisanu, mphamvu ya Zostavax ikhoza kuchepa pakapita nthawi. CDC ikulimbikitsa kupeza katemera watsopano wa shingles, Shingrix, ngakhale mutalandira kale katemera wa Zostavax m'mbuyomu.
Kodi chimachitika ndi chiyani ngati simupeza kuwombera kwachiwiri kwa Shingrix?
Kuwombera kwachiwiri kwa Shingrix ndikofunikira kuti muwonetsetse chitetezo chathunthu ndi katemerayu. Komabe, simuyenera kuda nkhawa ngati padutsa miyezi yoposa isanu ndi umodzi musanalandire cholimbikitsacho. Onetsetsani kuti mwalandira kuwombera kwachiwiri pafupi ndi miyezi iwiri kapena isanu ndi umodzi momwe mungathere.
