Tresiba vs. Lantus: Kusiyana, kufanana, ndi zomwe zili zabwino kwa inu
Mankhwala osokoneza bongo Vs. MnzanuKuwunika kwa mankhwala osokoneza bongo & kusiyana kwakukulu | Zinthu zothandizira | Mphamvu | Kuphunzira inshuwaransi ndikufanizira mtengo | Zotsatira zoyipa | Kuyanjana kwa mankhwala | Machenjezo | FAQ
Matenda a shuga ndi matenda omwe imakhudza kupitirira 10% mwa anthu aku United States, omwe ali ndi 1.5 miliyoni omwe amapezeka mwatsopano chaka chilichonse. Matenda a shuga amapezeka m'njira ziwiri: Mtundu 1 ndi Mtundu 2. Ndi mtundu woyamba wa matenda ashuga, thupi silimatulutsa insulini yofunikira kuti muchepetse kuchuluka kwa magazi m'magazi, omwe nthawi zina amatchedwa shuga wamagazi. Pachifukwa ichi, jakisoni wa insulin ndiye mankhwala oyamba. Thupi la odwala matenda ashuga amtundu wa 2 limapanga insulini koma siligwiritsa ntchito moyenera. Mtundu wachiwiri ndiofala kwambiri ku United States. Nthawi zina, zakudya, masewera olimbitsa thupi, ndi / kapena mankhwala akumwa ashuga amatha kuchepetsa shuga m'magazi mokwanira. Nthaŵi zambiri, komabe, jakisoni wa insulini angafunike kuti muchepetse kuchuluka kwa shuga m'magazi amtundu wa 2 ashuga.
Tresiba ndi Lantus ndi zitsanzo ziwiri za basal insulin, yomwe nthawi zina imatchedwa maziko kapena insulin yayitali. Mtundu uwu wa insulini umatsimikizira kuchuluka kwa shuga wamagazi tsiku lonse.
Kodi pali kusiyana kotani pakati pa Tresiba ndi Lantus?
Tresiba (insulin degludec) ndi mankhwala okhaokha ojambulidwa ndi basal insulini omwe amagwiritsidwa ntchito pochizira mtundu wa 1 ndi Type 2 shuga mellitus ndipo amapangidwa ndi Novo Nordisk, Inc. Insulin imathandizanso kuwongolera mafuta ndi mapuloteni kagayidwe kake. Ma insulins a biosynthetic amakhala ngati njira yothandizira odwala matenda ashuga kubwezeretsa mafuta awo, mapuloteni, ndi kagayidwe kazakudya.
Hafu ya moyo wa Tresiba ndi maola 25 ndipo alibe pachimake pachidziwikire. Kutalika kwa ntchito kwa Tresiba kumapereka shuga wokhazikika m'magazi tsiku lonse ndikumangowamwa kamodzi tsiku lililonse. Palibe mtundu wa Tresiba womwe ulipo.
Lantus (insulini glargine) ndi mankhwala okhaokha ojambulidwa ndi basal insulin omwe amagwiritsidwa ntchito pochizira Type 1 ndi Type 2 diabetes mellitus. Lantus amapangidwa ndi Sanofi. Lantus ndi Tresiba amagwiranso ntchito momwemo kuti alimbikitse kugwiritsa ntchito bwino mafuta, mapuloteni, ndi chakudya mwa odwala matenda ashuga. Hafu ya moyo wa Lantus ili pafupifupi maola 12 ndipo imayikidwa kamodzi patsiku. Lantus imaperekedwa mobisa ndipo imapezeka ngati njira yothetsera jakisoni wa 10 ml mu 100 mayunitsi / ml. Imapezekanso mu cholembera cha Lantus Solostar chimodzimodzi.
Palibe generic yovomerezeka ya FDA ya Lantus. Basaglar, komanso insulin glargine, ndi biosimilar insulin ku Lantus ndipo itha kukhala yotsika mtengo nthawi zina. Toujeo, yemwenso insulin glargine, ndi chinthu chatsopano chomwe chimakhazikika kwambiri pamayunitsi 300 / ml. Izi zitha kukhala zothandiza kwa odwala omwe amamwa kwambiri kuti achepetse jakisoni.
| Kusiyana kwakukulu pakati pa Tresiba ndi Lantus | ||
|---|---|---|
| Tresiba | Lantus | |
| Gulu la mankhwala osokoneza bongo | Biosynthetic insulin (insulin analog) | Biosynthetic insulin (insulin analog) |
| Chizindikiro cha Brand / generic | Mtundu | Mtundu |
| Kodi dzina lachibadwa ndi liti? | Jekeseni wa insulini | Insulini glargine |
| Kodi mankhwalawa amabwera mwa mawonekedwe ati? | Yankho m'jekeseni mu pulogalamu yobweretsera FlexPen | Yankho m'jekeseni ya vial kapena Solostar cholembera |
| Kodi mulingo woyenera ndi uti? | Zimadalira magulu a shuga m'magazi | Zimadalira magulu a shuga m'magazi |
| Kodi mankhwalawa amatenga nthawi yayitali bwanji? | Zosatha | Zosatha |
| Ndani amagwiritsa ntchito mankhwalawa? | Ana ndi akulu | Ana 6 kapena kupitirira, akulu |
Mukufuna mtengo wabwino pa Tresiba?
Lowani zidziwitso zamtengo wa Tresiba kuti mudziwe kuti mitengo isintha liti!
Pezani zidziwitso zamitengo
Zomwe amathandizidwa ndi Tresiba ndi Lantus
Tresiba ndi Lantus amawonetsedwa m'mankhwala a Type 1 ndi Type 2 diabetes mellitus. Anthu omwe ali ndi matenda a shuga a mtundu woyamba alibe insulini, ndipo majakisoni obayidwa ngati Tresiba ndi Lantus amakhala othandizira. Anthu omwe ali ndi Type 2 atha kukhala ndi insulin yocheperako, koma amakhalanso osagwiritsa ntchito insulin, kutanthauza kuti thupi lawo siligwiritsa ntchito insulini yomwe imapanga bwino. Tresiba ndi Lantus amakhala m'malo mwa insulin ndikuthandizira pamtundu wamatenda amtunduwu.
| Mkhalidwe | Tresiba | Lantus |
| Matenda a shuga Mtundu 1 | Inde | Inde |
| Matenda a shuga Mtundu 2 | Inde | Inde |
Kodi Tresiba kapena Lantus ndiwothandiza kwambiri?
Kusanthula kwa meta Maphunziro azachipatala a 15 lofalitsidwa mu 2019 linayang'ana deta kuchokera kwa opitilira 16,000 ophatikizidwa. Tresiba adachepetsa kwambiri kuchuluka kwa shuga m'magazi, koma pazonse, zotsatira za Tresiba ndi Lantus pa hemoglobin A1C (HbA1C) zinali zofanana. Tresiba anali ndi mwayi wocheperako wochititsa hypoglycemia. Ofufuzawo adazindikira kuti ngakhale kulamulira kwa glycemic kunali kofanana, Tresiba atha kusankhidwa chifukwa cha kuchepa kwa mwayi wa hypoglycemia.
KU kusanthula meta lofalitsidwa mu 2018 linali ndi zotsatira zofananira. Tresiba anali ocheperako chifukwa cha zochitika za hypoglycemia. Pachifukwa ichi, Tresiba atha kusankhidwa kuposa Lantus.
Nkhaniyi sikuti ikupereka upangiri wazachipatala. Wothandizira zaumoyo wanu adzasankha mitundu iti ya insulin yomwe ingakuthandizeni.
Mukufuna mtengo wabwino ku Lantus?
Lowani zidziwitso zamitengo ya Lantus kuti mudziwe kuti mitengo isintha liti!
Pezani zidziwitso zamitengo
Kuphunzira ndi kuyerekezera mtengo wa Tresiba vs. Lantus
Tresiba ndi mankhwala a insulini omwe nthawi zambiri amakhala ndi inshuwaransi zamalonda komanso mapulani azamankhwala a Medicare. Ndi mapulani ena, pakhoza kukhala zoletsa zoyambira, ndipo mungafune kuwona zomwe mukufotokoza ndi pulani yanu kapena mankhwala. Mtengo wapakati pa 3 ml cholembera cha Tresiba Flextouch 100 unit / ml ndi pafupifupi $ 400 popanda inshuwaransi. Mutha kulipira mtengo wochotseredwa pafupifupi $ 350 ndi coupon kuchokera ku SingleCare.
Lantus ndi mankhwala a insulini omwe nthawi zambiri amakhala ndi inshuwaransi zamalonda komanso mapulani azamankhwala ambiri a Medicare. Zoletsa zoyambilira zingakhudzenso kufalitsa kwa Lantus. Mtengo wapakati wa cholembera cha 3 ml ndi pafupifupi $ 100, koma ndimaponi ochokera ku SingleCare, mutha kulipira pafupifupi $ 70.
Ndikofunika kudziwa kuti cholembera chimodzi chamtundu uliwonse wa insulini sichikhala ndi nthawi yofanana kwa wodwala aliyense. Izi zimadalira mulingo wa insulini woperekedwa kwa wodwala aliyense.
| Tresiba | Lantus | |
| Nthawi zambiri amakhala ndi inshuwaransi? | Inde | Inde |
| Nthawi zambiri amakhala ndi Medicare Part D? | Inde | Inde |
| Mlingo woyenera | 1, 3 ml Flextouch 100 unit / ml cholembera | 1, 3 ml Solostar 100 unit / ml cholembera |
| Wopanga Medicare wamba | Zimasiyanasiyana kutengera dongosolo | Zimasiyanasiyana kutengera dongosolo |
| Mtengo wosakwatiwa | $ 350 + | $ 70 + |
Zotsatira zoyipa za Tresiba vs. Lantus
Tresiba ndi Lantus onse amatha kuyambitsa hypoglycemia, kapena shuga wotsika magazi. Chizolowezichi chimakhala chosiyanasiyana kutengera zinthu monga wodwalayo ali mtundu wa 1 kapena mtundu wachiwiri wa matenda ashuga, ndi mankhwala ena otani a insulin kapena mankhwala ashuga omwe wodwalayo angagwiritse ntchito, komanso zakudya. Mukamagwiritsa ntchito Tresiba kapena Lantus okhala ndi ma insulini ochita zinthu mwachidule kapena mwachangu, ngozizi zimawonjezeka.
Odwala ayenera kukhala ndi mwayi wowunika kuchuluka kwa magazi m'magazi ndi mita yachikhalidwe kapena njira yowunikira glucose (CGMS). Odwala ayeneranso kuphunzitsidwa zizindikilo za hypoglycemia, popeza zitha kupha moyo. Izi zimaphatikizapo kugwedezeka, mutu wopepuka, kusokonezeka kwamaganizidwe, nseru, kusawona bwino, komanso kupweteka mutu. Hypoglycemia ikhoza kusinthidwa ndikulowetsedwa kwa shuga kapena kuyendetsa jekeseni wa Glucagon.
Zochita patsamba la jakisoni zitha kukhala zovuta kwa wodwalayo. Izi zingaphatikizepo kufiira, kuyabwa, kapena kuvulala. Malo ozungulira jekeseni angathandize kuchepetsa kapena kuchepetsa izi.
Mndandandawu sikuti ukhale mndandanda wazomwe zingachitike. Chonde funsani omwe akukuthandizani kuti mupeze mndandanda wathunthu.
| Tresiba | Lantus | |||
| Zotsatira zoyipa | Zoyenera? | Pafupipafupi | Zoyenera? | Pafupipafupi |
| Thupi lawo siligwirizana | Inde | 0.9% | Inde | Osatanthauziridwa |
| Kuyabwa | Inde | Osatanthauziridwa | Inde | Osatanthauziridwa |
| Kutupa | Inde | Osatanthauziridwa | Inde | Osatanthauziridwa |
| Jekeseni wa jakisoni | Inde | 3.8% | Inde | Osatanthauziridwa |
| Kukhazikika kwa khungu kapena kupindika pamalo opangira jakisoni (lipodystrophy) | Inde | 0.3% | Inde | Osatanthauziridwa |
| Mutu | Inde | 12% | Inde | 5-10% |
| Kulemera | Inde | Osatanthauziridwa | Inde | Osatanthauziridwa |
| Hypoglycemia (shuga wotsika magazi) | Inde | 10-12% | Inde | 6-10% |
| Kutupa kwa manja ndi mapazi (zotumphukira edema) | Inde | 0.9-3% | Inde | makumi awiri% |
Gwero: Tresiba ( Tsiku ndi Tsiku Lantus ( Tsiku ndi Tsiku )
Kuyanjana kwa mankhwala a Tresiba vs. Lantus
Pali mitundu yambiri ya mankhwala ochepetsa matenda ashuga, ndipo nthawi zambiri, anthu omwe ali ndi matenda a shuga amtundu wa 2 angafunike kuphatikiza mitundu yosiyanasiyana ya maantibayotiki kupewa hyperglycemia (shuga wokwera m'magazi). Tsoka ilo, kuphatikiza kwa mankhwala angapo omwe cholinga chake ndikuchepetsa shuga m'magazi kumatha kuchepetsa kuchuluka kwa shuga, zomwe zimapangitsa hypoglycemia. Odwala ayenera kuyang'aniridwa bwino akamagwiritsa ntchito Tresiba ndi Lantus kuphatikiza mankhwala ena ochepetsa matenda ashuga monga metformin ndi glyburide. Thiazolidinediones, monga pioglitazone, imatha kupangitsa odwala makamaka kukhala ndi hypoglycemia. Mlingo wanu wa Tresiba kapena Lantus ungafunikire kusinthidwa pafupipafupi.
Mankhwala wamba omwe amadziwika kuti angiotensin-converter enzyme (ACE) inhibitors awonetsedwa kuti amachulukitsa chidwi cha insulin. Mukamagwiritsa ntchito mankhwalawa kuti muchepetse kuthamanga kwa magazi kwa odwala matenda ashuga akamwenso Tresiba kapena Lantus, chiopsezo cha hypoglycemia chimawonjezeka. Odwala ayenera kuyang'aniridwa ngati ali ndi zizindikiro za hypoglycemia ngati kuphatikiza uku kukuwoneka kuti ndikofunikira.
Izi sizitanthauza kuti pakhale mndandanda wathunthu wamagulu azakumwa a Tresiba ndi Lantus. Chonde funsani wamankhwala wanu kapena wothandizira zaumoyo kuti mumve mndandanda wonse.
| Mankhwala osokoneza bongo | Gulu la mankhwala osokoneza bongo | Tresiba | Lantus |
| Benazepril Wolemba Enalapril Zosakaniza Lisinopril Quinapril | Angiotensin-otembenuza enzyme (ACE) inhibitors | Inde | Inde |
| Isocarboxazid Selegiline Phenelzine | Monoamine oxidase (MAO) zoletsa | Inde | Inde |
| Metformin Glyburide Glipizide Wobwezeretsanso Pioglitazone Sitagliptin Saxagliptin | Mankhwala osokoneza bongo | Inde | Inde |
| Sulfamethoxazole | Mankhwala a Sulfonamide | Inde | Inde |
| Hydrochlorothiazide Furosemide Chlorthalidone | Okodzetsa | Inde | Inde |
| Prednisone Methylprednisolone | Corticosteroids | Inde | Inde |
| Chlorpromazine Fluphenazine Zowonjezera | Zotsatira za Phenothiazine | Inde | Inde |
| Lifiyamu Clozapine Olanzapine | Mankhwala oletsa antipsychotic | Inde | Inde |
| Estradiol Ethinyl Estradiol Norethindrone Kutalikirana Desogestrel Progesterone | Njira zolera zapakamwa | Inde | Inde |
| Atenolol Bisoprolol Chosema Zolemba Zamgululi Sotalol | Oletsa Beta | Inde | Inde |
| MulembeFM Liothyronine | Mahomoni a chithokomiro | Inde | Inde |
| Asipilini Magnesium salicylate Bismuth subsalicylate | Ma Salicylates | Inde | Inde |
| Fluoxetine | Kusankha serotonin reuptake inhibitor (SSRI) | Inde | Inde |
Machenjezo a Tresiba ndi Lantus
Tresiba ndi Lantus amakhala pachiwopsezo cha hypoglycemia, kapena kutsika kwa magazi m'magazi. Odwala a Tresiba kapena Lantus ayenera kudziwa zizindikilo za hypoglycemia, zomwe zimaphatikizapo kugwedezeka, mutu wopepuka, kusokonezeka kwamaganizidwe, nseru, kusawona bwino, komanso kupweteka mutu.
Hypokalemia, kapena potaziyamu yotsika, ndichinthu choopsa chomwe chingachitike chokhudzana ndi kugwiritsa ntchito kwa Tresiba kapena Lantus. Izi ndizofunikira makamaka kwa odwala omwe ali ndi vuto la impso kapena omwe amatha kumwa mankhwala a potaziyamu monga furosemide.
Zipangizo zoperekera insulini, monga zolembera za Flextouch kapena Solostar, komanso masingano a pensulo ndi ma syringe, siziyenera kugawidwa pakati pa odwala. Pali chiopsezo chodetsedwa pamtanda ndi tizilombo toyambitsa matenda timagazi komanso matenda. Odwala ayenera kulandira maphunziro ndi upangiri pazithandizo zoyambirira za matenda ashuga, kuphatikiza kugwiritsa ntchito singano mosamala.
Tresiba ndi Lantus amapangidwira mankhwala ochepa okha. Sayenera kupatsidwa mankhwala osokoneza bongo kapena kudzera m'mitsempha.
Mafunso omwe amafunsidwa pafupipafupi za Tresiba vs. Lantus
Tresiba ndi chiyani?
Tresiba (insulin degludec) ndi insulini yayitali yomwe imagwiritsidwa ntchito kamodzi kokha patsiku. Amapezeka kokha ngati mankhwala. Tresiba imapezeka mu FlexTouch cholembera dongosolo mozungulira magawo 100 / ml ndi 200 mayuniti / ml.
Lantus ndi chiyani?
Lantus (insulin glargine) ndi insulini yayitali yomwe imagwiritsidwa ntchito kamodzi kokha patsiku. Amapezeka kokha ngati mankhwala. Lantus imapezeka mu njira yotumizira Solostar pamagulu 100 / ml komanso mu 10 ml vial wa mayunitsi 100 / ml ya ndende.
Kodi Tresiba ndi Lantus ndi ofanana?
Tresiba ndi Lantus amatenga nthawi yayitali, koma osafanana. Tresiba ndi insulin degludec ndipo amakhala ndi theka la moyo wa maola 25. Lantus ndi insulin glargine ndipo amakhala ndi theka la moyo wa maola 12. Zonsezi zimayikidwa kamodzi tsiku lililonse.
Kodi Tresiba kapena Lantus ali bwino?
Ngakhale kulamulira kwa glycemic kuli kofanana pakati pa Tresiba ndi Lantus, zambiri zikuwonetsa kuti Tresiba mwina sangatengere zochitika zowopsa zama hypoglycemic. Pachifukwa ichi, Tresiba atha kusankhidwa, makamaka kwa odwala omwe amakonda kukhala ndi mbiri ya hypoglycemia.
Kodi ndingagwiritse ntchito Tresiba kapena Lantus ndili ndi pakati?
Tresiba amadziwika kuti ndi m'gulu la mimba C ndi Food and Drug Administration (FDA). Pali maphunziro azachipatala othandizira kugwiritsa ntchito komanso chitetezo chake pakubereka. Lantus ndi gawo B chifukwa chakuti kafukufuku wasonyeza kuti pali chiopsezo chochepa chovulaza mwana. Lantus amaonedwa kuti ndi wotetezeka pakati.
Kodi ndingagwiritse ntchito Tresiba kapena Lantus ndi mowa?
Kugwiritsa ntchito Tresiba kapena Lantus ndi mowa nthawi imodzi kumatha kutenga chiopsezo cha hypoglycemia. Kumwa mowa, makamaka pamimba yopanda kanthu, kumalepheretsa gluconeogenesis. Izi zimabweretsa chiopsezo chotalika cha shuga wotsika magazi.
Kodi insulin imafanana ndi Lantus?
Basaglar ndi yofanana ndi Lantus, ngakhale siyiyomwe imavomerezedwa ndi FDA ku Lantus ndipo siyikhala m'malo mwa Lantus. Lantus ndi Basaglar onse ndi insulin glargine m'magulu a 100 / ml.
Nthawi yabwino kutenga Tresiba ndi iti?
Tresiba atha kupatsidwa nthawi iliyonse patsiku osaganizira nthawi yakudya, koma ndikofunikira kupereka mankhwalawo nthawi yomweyo.
Kodi njira ina yabwino ku Tresiba ndi iti?
Toujeo ndi basal insulini yomwe imapezeka mgulu lalikulu la mayunitsi 300 / ml. Kukula kwakukulu m'mayendedwe am'munsi kumalola odwala omwe ali ndi mayeza ofunikira kwambiri kuti alowetse voliyumu yochepa.
