Zotsatira za Topamax ndi momwe mungapewere

Zambiri Zamankhwala

Zotsatira za Topamax | Machenjezo | Kuyanjana | Momwe mungapewere zovuta

Topamax (topiramate) ndi mankhwala omwe amatchedwa anticonvulsant mankhwala omwe amagwira ntchito muubongo kuti asatengeke. Yavomerezedwa ndi FDA kuyambira 1996 ya mankhwala a khunyu mwa ana ndi akulu omwe. Topamax imagwiritsidwanso ntchito pewani mutu waching'alang'ala mwa akulu . Amagwiritsidwanso ntchito ngati chizindikiro kwa chitani odwala omwe ali ndi matenda osokoneza bongo (amatchedwanso manic depression) ndipo amathandizira kuchepetsa thupi. Mankhwalawa amaperekedwa mu 25 mg mpaka 400 mg.

Topamax ndi yotetezeka kuti igwiritsidwe ntchito kwa nthawi yayitali mukamayamwa moyenera. Komabe, zovuta zingapo zomwe zimafala komanso mwina zowopsa zidanenedwapo ndi odwala ochepa. Palinso mankhwala angapo omwe angayambitse kuyanjana kovulaza kapena kukhala opanda ntchito akagwiritsidwa ntchito limodzi ndi Topamax. Nazi zonse zomwe muyenera kudziwa zakutenga Topamax mosamala, kuphatikizapo zomwe mungachite kuti muchepetse chiopsezo chokhala ndi zovuta zoyipa.

ZOKHUDZA: Kodi Topamax ndi chiyani? | Pezani makuponi a Topamax

Zotsatira zoyipa za Topamax

Zotsatira zoyipa zambiri zomwe zimakhudzana ndi Topamax zimawerengedwa kuti ndizochepa pang'ono. Zambiri zimatha kapena kuzimiririka mukamazolowera mankhwalawo. Ngati mukumane ndi izi, dziwitsani dokotala nthawi yomweyo chifukwa atha kuwonetsa zovuta zina. Izi ndi zotsatira zoyipa kwambiri za Topamax, malinga ndi wopanga :

• Kutaya njala, kusintha kwa kukoma, kuchepa thupi, kupweteka m'mimba, ngakhalenso anorexia
• Zotsatira za GI (nseru, kutsegula m'mimba, kudzimbidwa)
• Kutopa
• Paresthesia (kumva kulasalasa kapena kumenyedwa)
• Mavuto olankhula
• Kulephera kuzindikira (vuto ndi kukumbukira ndi kuganiza)
• Matenda opatsirana apamwamba
• Chizungulire
• Mantha
• Zomwe zimachitika pang'onopang'ono
• Zosintha zowoneka (kusawona, mitambo, kusuntha kwamaso)
• Malungo
• Kuchepetsa kukhudzidwa kapena kufooka

Kodi Topamax imakupangitsani kugona?

Kutenga Topamax kumatha kukupangitsani kuti muzisinza komanso kuzungulirazungulira. Muyenera kupewa kuyendetsa galimoto, kugwiritsa ntchito makina olemera, kapena kuchita zina zomwe zimafunikira kukhala tcheru mpaka mutadziwa momwe mankhwalawa amakukhudzirani. Chifukwa imatha kuyambitsa tulo, Topamax nthawi zambiri amatengedwa usiku.

Kodi Topamax imayambitsa ubongo wa ubongo?

Odwala nthawi zambiri amakhala ndi utsi wamaubongo, kapena kuchepa kuzindikira , poyambira Topamax. Ena amati amalephera kukonza mwachangu zambiri, mavuto azilankhulo, kapena kuganiza bwino. Kwa ena, chizindikirochi chimathera pomwe thupi limafanana ndi dosing. Ena angafunike kufunafuna njira zina za Topamax.

Kodi Topamax imapangitsa tsitsi lanu kugwa?

Malinga ndi Ma National Institutes of Health , Kutayika kwa tsitsi ndi zotsatira zoyipa za topiramate, koma wopanga Topamax samazilemba monga wamba. Tsitsi nthawi zambiri limakula msanga mukaleka kumwa mankhwala.

Zotsatira zoyipa za Topamax

Palinso zovuta zoyipa zomwe muyenera kudziwa mukamamwa Topamax. Zotsatirazi nthawi zambiri zimafuna kuchipatala kapena chithandizo chamankhwala, ndipo zimatha kubweretsa kuvulala kosatha kapena kuwopseza moyo.

• Metabolic acidosis (kutopa, kusowa njala, kugunda kwamtima mosasinthasintha, utsi wabongo)
• Kuchuluka kwa ammonia m'magazi (pamene Topamax imamwedwa ndi mankhwala okhala ndi valproic acid)
• Kukhumudwa kwatsopano kapena kukulira, nkhawa, kapena malingaliro ofuna kudzipha / machitidwe (omwe amapezeka mwa 1 mwa odwala 500)
• Kuchepetsa thukuta koma kutentha kwa thupi
• Glaucoma
• Matenda a Stevens-Johnson (khungu lotupa kwambiri, zotupa, khungu losenda)
• Kukula pang'onopang'ono kwa ana
• Kugwidwa mwadzidzidzi (ngati Topamax imayimitsidwa mwadzidzidzi)

Kodi Topamax ingasinthe umunthu wanu?

Ma Anticonvulsants ngati Topamax, amathanso kukhudza kwambiri zomwe zimapangitsa kuti munthu akhale ndi matenda amisala monga nkhawa, kukhumudwa, kapena mania. Topamax imatha kukhala ndi zovuta zingapo zamankhwala osokoneza bongo komanso neuropsychiatric, kuphatikiza iyi Matenda osokoneza bongo a topamax . Odwala ayenera kudziwa kusintha kwakanthawi pamalingaliro kapena momwe akumvera komanso kupita kuchipatala ngati akasintha kwambiri umunthu wawo.

Kodi Topamax ingayambitse kukumbukira kosatha?

Topamax itha kukhala yokhudzana ndi dementia ndipo iyenera kugwiritsidwa ntchito mosamala mu odwala okalamba . Komabe, sizinatsimikizidwe kuti Topamax imatha kubweretsa kukumbukira kosatha.

Topamax ndi kagayidwe kachakudya acidosis

Topamax ingayambitse kuchuluka kwa asidi m'magazi, otchedwa kagayidwe kachakudya acidosis . Izi zikachitika, thupi limatulutsa asidi mwachangu kwambiri, ndipo impso sizingafanane ndi kusefa. Pachifukwa ichi, odwala omwe ali ndi vuto la impso kapena matenda a impso ayenera kuyang'aniridwa kwambiri akamamwa Topamax.

Nthawi zovuta kwambiri, kagayidwe kachakudya acidosis kangayambitse impso, mantha, kapena kufa kumene. Matendawa amathanso kuyambitsa mafupa ofewa kapena ofewa komanso miyala ya impso, kuchepetsa kukula kwa ana, komanso kuvulaza mwana ali ndi pakati. Zizindikiro zama metabolic acidosis zimaphatikizapo kupuma mwachangu, kuthamanga kwa magazi, ulesi ndi kusokonezeka, komanso kusowa njala.

Matenda a topamax ndi maso

Topamax imatha kuyambitsa mavuto akulu amaso omwe angayambitse khungu. Myopia yovuta, yomwe imayambitsa kuyandikira, imatha kuyambitsa mutu kapena kusawona bwino chifukwa chakupsinjika m'maso. Odwala ananenanso zochitika zingapo za kutsekedwa kwa khungu lachiwiri la glaucoma, lomwe, ngati silichiritsidwa, limatha kubweretsa kuwonongeka kwa masomphenya. Odwala omwe amatenga Topamax ayenera kupita kuchipatala ngati akumana ndi zowawa m'maso kapena kusapeza bwino.

Machenjezo a Topamax

Musatenge Topamax ngati:

• zimakhala zosavomerezeka kwa iwo kapena zina mwa zosakaniza zake
• amwe mowa pasanathe maola 6 mutatenga Topamax
• mwakhala kapena mwakhalapo ndi izi:
  • Glaucoma kapena mavuto ena amaso
  • Matenda a impso
  • Matenda a acidosis
  • Matenda am'mapapo kapena kupuma
  • Mavuto amakono, kukhumudwa, malingaliro ofuna kudzipha kapena zochita
  • Matenda akukula
  • Mafupa ofewa kapena osweka (kufooka kwa mafupa, osteomalacia)
• mukukonzekera kutenga pakati kapena ngati mukuyamwitsa

Khalidwe lodzipha komanso malingaliro

Monga anticonvulsant, Topamax imakhudza mwachindunji zochitika zaubongo. Pafupi 1 mwa 500 Odwala omwe amamwa mankhwala a antiepileptic monga Topamax awonetsa kuti adakumana ndi malingaliro ofuna kudzipha, makamaka akamayamba mankhwala kapena kusintha miyezo.

Chifukwa cha izi, odwala amayenera kuyang'aniridwa mosalekeza ndikupita kuchipatala ngati akumana ndi nkhawa, mantha, kuyamba kapena kukhumudwa. Ngakhale ndizosowa, Topamax imatha kuchititsanso kusintha kwamakhalidwe kapena machitidwe, monga nkhanza kapena chiwawa, kukwiya, mphwayi, mkwiyo, kapena kukwiya. Uzani katswiri wa zamankhwala za izi.

Topamax ndi mimba

Ngati muli ndi pakati kapena mukukonzekera kutenga pakati, muyenera kudziwitsa dokotala posachedwa. Topamax imawonjezera chiopsezo chakulephera kubadwa pakamwa monga milomo yolukana ndi m'kamwa nthawi 16 . Kugwiritsira ntchito Topamax panthawi yoyembekezera kungayambitsenso vuto la mtima, mapapo, chigaza, ndi mafupa ngati ziwalo zolakwika. Zolakwika zina zobadwa zimatha kuphatikizira kupsyinjika kwa m'mapapo kwa wakhanda (PPHN), spina bifida, ndi zolakwika zina za neural tube, zomwe zitha kupha moyo.

Chifukwa chake, ndikofunikira kusamala kuti muchepetse zovuta zomwe zingachitike poyang'anira Mlingo wa Topamax ndi mankhwala ena panthawi yapakati. Kusiya mwadzidzidzi mankhwala ngati Topamax panthawi yoyembekezera sikuvomerezeka, chifukwa chake musasinthe kuchuluka kwanu kapena kusiya kumwa osalankhula ndi dokotala. Topamax iyenera kugwiritsidwa ntchito pochiza zinthu zomwe zingawopseze odwala.

Kuyanjana kwa Topamax

Pali mankhwala ambiri omwe amagulitsidwa ndi Topamax. Zotsatira zoyipa zamayendedwe amtunduwu zimachokera pakuchepa mpaka kufooka, ndikupangitsa kuti izi zitheke. Funsani dokotala musanatenge Topamax ngati muli ndi imodzi mwa mankhwala awa:

• Mapiritsi oletsa kubereka: Topamax ingachepetse mphamvu ndi zotsatira za mankhwala opatsirana pakamwa kapena mankhwala osamba omwe ali ndi estrogen. Njira yoletsa kubereka ngati kondomu kapena diaphragm yokhala ndi spermicide njira yabwino yodzitetezera potenga Topamax.
• Kulanda mankhwala: Tegretol (carbamazepine), Dilantin (phenytoin), Depakote (valproate), lamotrigine, ndi phenobarbital zitha kuchepetsa kuchuluka kwa zotsatira za Topamax mthupi lanu. Kutenga Depakote (valproate) molumikizana ndi Topamax kumakweza ammonia m'magazi anu. Izi zikachitika, mutha kukhala osokonezeka, osokonezeka, kapena mumavutika kuganiza.
• Mpweya wa anhydrase inhibitors: Mankhwala osokoneza bongo monga acetazolamide, dichlorphenamide, methazolamide, ndi dorzolamide amatha kuonjezera ngozi ya miyala ya impso ikatengedwa ndi Topamax.
• Mankhwala owopsa: Mankhwala ena opatsirana monga diphenhydramine, chlorpheniramine, hydroxyzine amatha kuonjezera mavuto monga chizungulire, kugona tulo, kapena kusokonezeka.
• Kupweteka kumachepetsa: Odwala omwe amatenga Topamax amatha kukhala ndi tulo, chizungulire, kapena kuvutika kuganiza akauzidwa molumikizana ndi mankhwala opweteka monga hydrocodone, oxycodone, morphine, kapena hydromorphone.
• Mankhwala osokoneza bongo: Topamax imachulukitsa ma lithiamu mthupi mukatengedwa pamodzi.
• Mankhwala a shuga: Glyburide kapena pioglitazone sizingathandize kuchepetsa shuga m'magazi kuti athe kuchiza matenda ashuga. Kutenga metformin ndi Topamax kumakhalanso koopsa, makamaka ngati wodwalayo ali ndi metabolic acidosis.

Kodi mutha kumwa tiyi kapena khofi ndi Topamax?

Topamax ikhoza kukulitsa kuchuluka kwa zakumwa za caffeine, zomwe zimatha kuchepetsa mphamvu zake mthupi, koma nthawi zambiri zimakhala zosakanikirana.

Kodi ndiyenera kudya chiyani ndikamamwa Topamax?

Mutha kutenga Topamax kapena wopanda chakudya. Popeza chimodzi mwazovuta zoyipa kwambiri zotenga Topamax ndi kagayidwe kachakudya acidosis, pewani kudya ketogenic (low carbohydrate, protein yowonjezera). Kudya zakudya zomwe zimalimbikitsa ketosis kumatha kuwonjezera chiopsezo cha miyala ya impso, yomwe imatha kupititsa patsogolo impso zanu.

Momwe mungapewere zotsatira zoyipa za Topamax

Kuti mumve zambiri za mankhwala, werengani Chitsogozo cha mankhwala a Topamax musanayambe mankhwala anu.

1. Ngati mukukumana ndi zovuta zilizonse, funsani omwe akukuthandizani. Kuyesa kosiyanasiyana kwa seramu kuti muwone momwe impso ndi chiwindi zimagwirira ntchito, mwachitsanzo, kumathandizanso kuchepetsa mavuto azovuta.
2. Dziwani zonse zomwe zimachitika ndi mankhwala. Mankhwala ena monga kulera pakamwa siwothandiza mukamamwa ndi Topamax, ndipo ena, monga mankhwala osokoneza bongo, amatha kukulitsa zovuta za Topamax.
3. Musatenge Topamax pasanathe maola asanu ndi limodzi mutamwa mowa.
4. Pewani kugwiritsa ntchito makina olemera, kuyendetsa galimoto, kapena kuchita zina zowopsa ngati Topamax ikupangitsani kugona kapena chizungulire.
5. Imwani madzi ambiri ndipo yesetsani kupewa kutaya madzi m'thupi komanso kudzimbidwa. Izi zitha kuthandiza kuchepetsa chiopsezo cha kupangidwa kwa miyala ya impso, zomwe zingathandize kupewa kagayidwe kachakudya acidosis.
6. Pewani kutsatira zakudya za ketogenic popewa kukula kwa miyala ya impso komanso kutha kwa kagayidwe kake ka acidosis.
7. Pitani kuchipatala mwachangu mukawona zosintha mwadzidzidzi kapena kusintha kwa kukhumudwa kapena malingaliro ofuna kudzipha.
8. Ngati ndinu mayi pa za kulera zakumwa, lingalirani kugwiritsa ntchito njira ina yotchingira kuti musatenge mimba. Imeneyi ndi imodzi mwa njira zabwino kwambiri zopewera chiopsezo cha kubadwa kwakukulu komwe kumakhudzana ndi kutenga Topamax.
9. Mukaphonya mlingo, imwani mukamakumbukira. Ngati ili pafupi nthawi ya mlingo wanu wotsatira, tulukani ndi kumwa mankhwala omwe akubwera. Musatenge ndalama zowirikiza kuti mupange mlingo wosowa.
10. Osasiya kutenga Topamax modzidzimutsa, chifukwa izi zimatha kuyambitsa khunyu, ngakhale simunakhalepo m'mbuyomu. Ngati mukufuna kusiya kumwa Topamax, dokotala wanu amachepetsa pang'onopang'ono mlingo wanu kuti akuchotseni pamankhwala.

Nthawi yoti muwone dokotala wa zotsatira zoyipa za Topamax

Zotsatira zambiri za Topamax zitha kukhala zowopsa ndikuwopseza moyo. Dziwitsani akatswiri azachipatala anu ndipo pitani kuchipatala nthawi yomweyo mukayamba kukumana ndi ena mwa iwo, makamaka omwe amawoneka kuti ndi ovuta.