Armodafinil vs. modafinil: Kusiyana, kufanana, ndi zomwe zili zabwino kwa inu
Mankhwala osokoneza bongo Vs. MnzanuKuwunika kwa mankhwala osokoneza bongo & kusiyana kwakukulu | Zinthu zothandizira | Mphamvu | Kuphunzira inshuwaransi ndi kufananiza mtengo | Zotsatira zoyipa | Kuyanjana kwa mankhwala | Machenjezo | FAQ
Mutha kukhala ndi tulo tofa nato masana ngati mumagwira ntchito usiku. Koma ndi chithandizo choyenera monga Armodafinil (Nuvigil) kapena modafinil (Provigil), mutha kukhala ogalamuka ndikumva tcheru. Mankhwalawa atha kulembedwa ngati mwapezeka kuti muli ndi vuto la kusintha ntchito (SWD), narcolepsy, kapena obstructive sleep apnea (OSA). Monga othandizira-kutsitsimutsa, armodafinil ndi modafinil ali ndi zotsatira zokopa.
Ngakhale magwiridwe antchito awo sakudziwika, armodafinil ndi modafinil amakhulupirira kuti amagwira ntchito m'katikati mwa manjenje (CNS) ndikulimbikitsa zochitika za dopamine muubongo. Zotsatira zawo zitha kukhala zofanana ndi zowonjezera zina monga amphetamine (Adderall) ndi methylphenidate (Concerta). Komabe, ndi osiyana mosiyanasiyana kuposa zolimbikitsa zina.
Onse awiri armodafinil ndi modafinil ndi ndandanda ya Ndandanda IV yomwe imatha kuzunza komanso kudalira. Ndi zinthu zoyendetsedwa zomwe zimapezeka ndi mankhwala.
Kodi pali kusiyana kotani pakati pa armodafinil ndi modafinil?
Armodafinil, yogulitsidwa pansi pa dzina la Nuvigil, ndi mankhwala atsopano poyerekeza ndi modafinil. Idavomerezedwa mu 2007 ngati R-enantiomer ya modafinil. Enantiomers ndi mamolekyu omwe ali zithunzi zofananira - ganizani magolovesi akumanzere ndi kumanja. Mwanjira iyi, armodafinil ili ndi mawonekedwe osiyana pang'ono poyerekeza ndi modafinil.
Armodafinil atha kukhala ndi theka la moyo poyerekeza ndi modafinil (dzina lodziwika kuti Provigil). Nthawi zina, armodafinil imatha kuonedwa ngati mankhwala amphamvu omwe ali ndi zotsatira zabwino zodzuka. Ngakhale mankhwala onsewa amatha kukhala ndi zotsatirapo zofananira, zovuta zina zimatha kupezeka pamankhwala ena motsutsana ndi enawo.
| Kusiyana kwakukulu pakati pa armodafinil ndi modafinil | ||
|---|---|---|
| Armodafinil | Modafinil | |
| Gulu la mankhwala osokoneza bongo | Mankhwala osokoneza bongo Wothandizira kutsatsa | Mankhwala osokoneza bongo Wothandizira kutsatsa |
| Chizindikiro cha Brand / generic | Mitundu yama brand ndi generic ikupezeka | Mitundu yama brand ndi generic ikupezeka |
| Kodi dzina lake ndi ndani? | Nuvigil | Provigil |
| Kodi mankhwalawa amabwera mwa mawonekedwe ati? | Piritsi lapakamwa | Piritsi lapakamwa |
| Kodi mulingo woyenera ndi uti? | 150 mg kamodzi patsiku | 200 mg kamodzi patsiku |
| Kodi mankhwalawa amatenga nthawi yayitali bwanji? | Kutalika kapena kulangizidwa ndi dokotala | Kutalika kapena kulangizidwa ndi dokotala |
| Ndani amagwiritsa ntchito mankhwalawa? | Akuluakulu komanso achinyamata azaka 17 kapena kupitilira apo | Akuluakulu komanso achinyamata azaka 17 kapena kupitilira apo |
Mukufuna mtengo wabwino kwambiri pa armodafinil?
Lowani zidziwitso zamitengo ya armodafinil ndikupeza kuti mitengo ikasintha liti!
Pezani zidziwitso zamitengo
Zomwe zimathandizidwa ndi armodafinil ndi modafinil
Armodafinil ndi modafinil ndi mankhwala omwe amavomerezedwa ndi FDA kuti azitha kugona tulo masana okhudzana ndi matenda osokoneza bongo, kusinthasintha kwa ntchito, komanso kupuma tulo tating'onoting'ono. Matendawa amadziwika ndi kupuma kokwanira komwe kumabweretsa tulo tambiri. Mankhwala onsewa amathandizira kuti anthu omwe ali ndi vuto lotopa komanso kugona azikhala osangalala tsiku lonse.
Armodafinil ndi modafinil adaphunziranso pazinthu zina. Ena maphunziro onetsani kuti modafinil ikhoza kukhala njira yothandiza yothandizira kutopa komwe kumachitika chifukwa cha khansa ndi khansa. Kwa achikulire omwe akulandila khansa mwachangu, modafinil itha kuthandizira kuthetsa kutopa kwambiri kuchokera ku chemotherapy.
Mwa iwo omwe ali ndi matenda ofoola ziwalo , kuchepa kwa modafinil kungakhale kothandiza pochiza zizindikiro za kutopa. Komabe, zambiri zimafotokoza kuti modafinil sayenera kugwiritsidwa ntchito ngati mzere woyamba pazomwe zachitika.
Ntchito zina zomwe sizinalembedwe zimaphatikizaponso chithandizo chamavuto amisala monga kukhumudwa ndi kuchepa kwa chidwi-matenda oopsa (ADHD). Armodafinil kapena modafinil atha kukhala othandiza kuthana ndi zovuta zamatendawa koma samalimbikitsidwa ngati njira zoyambirira zochizira.
| Mkhalidwe | Armodafinil | Modafinil |
| Kugonana | Inde | Inde |
| Kusintha kwa ntchito kosintha | Inde | Inde |
| Kulepheretsa kugona tulo | Inde | Inde |
| Kutopa kokhudzana ndi khansa | Kutumiza | Kutumiza |
| Kutopa kokhudzana ndi sclerosis | Kutumiza | Kutumiza |
| Matenda amisala monga kukhumudwa ndi ADHD | Kutumiza | Kutumiza |
Mukufuna mtengo wabwino pa modafinil?
Lowani zidziwitso zamitengo ya modafinil ndikupeza kuti mitengo ikasintha liti!
Pezani zidziwitso zamitengo
Kodi armodafinil kapena modafinil ndiyothandiza kwambiri?
Armodafinil ndi modafinil nawonso amathandizanso pochiza tulo pamavuto ogona monga matenda opatsirana pogonana, zolepheretsa kugona tulo, komanso vuto la magwiridwe antchito. Komabe, armodafinil itha kukhala ndi zotsatira zokhalitsa poyerekeza ndi modafinil.
M'masabata a 12 osasinthika, mayesero azachipatala, onse a armodafinil ndi modafinil kugona bwino mu maphunziro omwe amagwira ntchito usiku. Zotsatira zidapeza kuti armodafinil ndi modafinil anali ofanana ndi ziwopsezo zofananira.
Mu kusanthula meta poyerekeza armodafinil ndi modafinil yolepheretsa kugona tulo, mankhwala onsewa amapezeka kuti ndi othandiza pochotsa tulo. Odwala omwe amamwa mankhwala omwe amalephera kulandira mankhwalawa amakhala osangalala masana.
Armodafinil yawonetsedwa kuti yakwera kwambiri kuchuluka kwa plasma m'thupi pambuyo pake masana. Mulingo wapamwamba wa armodafinil m'thupi umatha kubweretsa kudzuka bwino poyerekeza ndi modafinil.
Ngakhale mankhwalawa atha kugwiritsidwa ntchito ngati chithandizo chogona kwambiri, ndibwino kukaonana ndi dokotala kuti akuthandizeni. Pakadali pano, palibe kafukufuku wotsimikiza yemwe akuti imodzi ndiyothandiza kuposa inayo.
Kuphunzira ndi kuyerekezera mtengo wa armodafinil vs. modafinil
Armodafinil nthawi zambiri amalembedwa ngati piritsi la 250 mg lomwe limatengedwa kamodzi tsiku lililonse. Amapezeka kwambiri ngati mankhwala achibadwa omwe amapangidwa ndi Medicare ndi mapulani a inshuwaransi. Generic Nuvigil atha kukhala ndi mtengo wogulitsa wopitilira $ 500. Mtengo uwu ukhoza kutsitsidwa ndi khadi yotsitsa ya SingleCare. M'malo molipira mitengo yokwera, armodafinil itha kugulidwa pamtengo wotsika mpaka $ 277.
Kutengera pulani ya inshuwaransi yanu, modafinil atha kuphimbidwa. M'malo mwake, Medicare ndi mapulani ambiri a inshuwaransi amatenga modafinil pazovomerezeka. Mtengo wapakati wa modafinil ukhoza kuwononga $ 600. Kumasitolo omwe akutenga nawo mbali, mutha kugwiritsa ntchito khadi yosungira ya SingleCare kuti musunge ndalama. Kusungidwa kwa modafinil kumatha kubweretsa mtengo wotsika wa $ 35- $ 280 kutengera mankhwala omwe mumagwiritsa ntchito.
| Armodafinil | Modafinil | |
| Nthawi zambiri amakhala ndi inshuwaransi? | Inde | Inde |
| Nthawi zambiri amadzazidwa ndi Medicare? | Inde | Inde |
| Mlingo woyenera | Mapiritsi a 150 mg | Mapiritsi 200 mg |
| Wopanga Medicare wamba | $ 15- $ 217 | $ 11- $ 392 |
| Mtengo wosakwatiwa | $ 277 | $ 35- $ 280 |
Zotsatira zoyipa za armodafinil vs. modafinil
Zotsatira zoyipa zomwe zimakhudzana ndi armodafinil ndi modafinil ndizopweteketsa mutu, nseru, chizungulire, komanso kugona tulo. Modafinil atha kuyambitsa zina zotsatira zoyipa monga mantha, kuchulukana kwammphuno (rhinitis), kutsegula m'mimba, ndi kupweteka msana.
Mankhwala onsewa amathanso kuyambitsa mkamwa wouma, kudzimbidwa (dyspepsia), komanso nkhawa. Zotsatira zoyipa zokhudzana ndi kuchepa thupi zitha kuchitika. Anthu ena omwe amatenga armodafinil kapena modafinil amatha kuchepa kudya.
Zotsatira zina zosawerengeka koma zoyipa zimaphatikizapo kusokonezeka monga kuthamanga ndi kupuma movutikira. Zotsatira zamisala monga kukhumudwa kapena psychosis ndizothekanso. Pitani kuchipatala ngati mukumva izi.
| Armodafinil | Modafinil | |||
| Zotsatira zoyipa | Zoyenera? | Pafupipafupi | Zoyenera? | Pafupipafupi |
| Mutu | Inde | 17% | Inde | 3. 4% |
| Nseru | Inde | 7% | Inde | khumi ndi chimodzi% |
| Mantha | Inde | 1% | Inde | 7% |
| Kusowa tulo | Inde | 5% | Inde | 5% |
| Chizungulire | Inde | 5% | Inde | 5% |
| Kutsekula m'mimba | Inde | 4% | Inde | 6% |
| Ululu wammbuyo | Ayi | - | Inde | 6% |
| Kuchulukana m'mphuno | Ayi | - | Inde | 7% |
| Kudzimbidwa | Inde | awiri% | Inde | 5% |
| Pakamwa pouma | Inde | 4% | Inde | 4% |
| Nkhawa | Inde | 4% | Inde | 5% |
| Kuchepetsa chilakolako | Inde | 1% | Inde | 4% |
Uwu sungakhale mndandanda wathunthu. Funsani dokotala wanu kapena wamankhwala pazotsatira zomwe zingachitike.
Gwero: DailyMed ( chododafinil ), Tsiku Lililonse ( modafinil )
Kuyanjana kwa mankhwala a armodafinil vs. modafinil
Armodafinil ndi modafinil amagawana zolumikizana chimodzimodzi. Mankhwalawa amatha kukhala ngati olowerera mavitamini a CYP3A4 komanso zoletsa mavitamini a CYP2C19. Mwanjira ina, zimatha kukhudza momwe mankhwala ena amasinthidwa mthupi.
Armodafinil ndi modafinil zitha kuchepetsa mphamvu ya steroidal njira zolerera . Njira zina zakulera zimalimbikitsidwa mukamalandira chithandizo cha armodafinil kapena modafinil komanso kwa mwezi umodzi mutasiya kumwa mankhwalawa.
Armodafinil ndi modafinil zitha kukulitsa chilolezo cha cyclosporine mthupi. Ngati atengedwa pamodzi, mphamvu ya cyclosporine ikhoza kuchepetsedwa. Kumbali inayi, armodafinil ndi modafinil zitha kukulitsa kuchuluka kwa mankhwala ena omwe amadziwika kuti magawo a CYP2C19. Kuchuluka kwa mankhwala kumatha kubweretsa zovuta.
| Mankhwala osokoneza bongo | Gulu la Mankhwala | Armodafinil | Modafinil |
| Ethinyl estradiol Norethindrone | Njira zolerera za Steroidal | Inde | Inde |
| Cyclosporine | Wodwalitsa | Inde | Inde |
| Omeprazole Phenytoin Diazepam | Magawo a CYP2C19 | Inde | Inde |
Izi sizingakhale mndandanda wathunthu wazomwe zingachitike mukamagwiritsa ntchito mankhwala osokoneza bongo. Funsani dokotala ndi mankhwala onse omwe mukumwa.
Machenjezo a armodafinil ndi modafinil
Onse awiri armodafinil ndi modafinil amatha kuyambitsa ziwopsezo zazikulu. Mankhwalawa ayenera kuthetsedwa nthawi yomweyo ngati pali zotupa zazikulu. Musamamwe mankhwalawa ngati mukukayikira kuti ali ndi vuto lililonse pazinthu zawo.
Mlingo wa armodafinil kapena modafinil angafunikire kusintha kuti athe kugona tulo masana. Ngakhale kupititsa patsogolo mankhwala, kugona kosalekeza kumatha kuchitika. Chifukwa chake, ndikofunikira kupewa kuyendetsa galimoto kapena kuchita nawo zoopsa mukamayambitsa mankhwala ngati armodafinil kapena modafinil.
Armodafinil ndi modafinil zimatha kuyambitsa matenda amisala makamaka kwa iwo omwe ali ndi mbiri ya psychosis , kukhumudwa, kapena kukwiya. Mankhwalawa ayenera kuyang'aniridwa kapena kutayidwa pakakhala zovuta zamankhwala.
Mankhwala osokoneza bongo amatha kuyambitsa mavuto mumtima ndi mumtima. Omwe ali ndi kuthamanga kwa magazi angafunike kuyang'aniridwa akamayamba armodafinil kapena modafinil. Funsani dokotala ngati mukumva kupweteka pachifuwa, kupuma pang'ono, kapena kugundana (kugunda kwamtima mwachangu).
Mafunso omwe amafunsidwa kawirikawiri za armodafinil vs. modafinil
Kodi armodafinil ndi chiyani?
Armodafinil imadziwikanso ndi dzina lake lotchedwa Nuvigil. Armodafinil imagwiritsidwa ntchito pochiza tulo tambiri kuchokera ku narcolepsy ndi mavuto ena ogona. Imabwera mu 50 mg, 150 mg, 200 mg, ndi mapiritsi a 250 mg.
Modafinil ndi chiyani?
Modafinil ndi dzina lodziwika bwino la Provigil. Modafinil ndivomerezedwa ndi FDA kuti athetse tulo masana omwe amabwera chifukwa chakusowa tulo. Imatha kuthana ndi vuto lobanika kutulo, kunyong'onyeka , ndi kusintha kosintha kwa ntchito.
Kodi armodafinil ndi modafinil ndizofanana?
Armodafinil ndi modafinil ali ndi zinthu zofananira koma sizofanana. Armodafinil ili ndi R-enantiomer ya modafinil. Modafinil ili ndi kusakanikirana kwamtundu wa R- ndi S-modafinil.
Kodi armodafinil kapena modafinil ndibwino?
Armodafinil ndi modafinil ndizofanana pakugwira ntchito komanso chitetezo. Komabe, armodafinil atha kukhala nayo misinkhu apamwamba m'thupi kupitirira masana. Zotsatira za armodafinil zitha kukhala nthawi yayitali poyerekeza ndi modafinil.
Kodi ndingagwiritse ntchito armodafinil kapena modafinil ndili ndi pakati?
Ayi. Armodafinil ndi modafinil samalimbikitsidwa nthawi yapakati. Kambiranani zosankha zanu ndi dokotala ngati muli ndi pakati kapena mukuyamwitsa.
Kodi ndingagwiritse ntchito armodafinil kapena modafinil ndi mowa?
Sikoyenera kutenga armodafinil kapena modafinil mukamamwa mowa. Kumwa mowa muli pa armodafinil kapena modafinil kumatha kuyambitsa mavuto.
Kodi mungatenge armodafinil ndi modafinil limodzi?
Armodafinil ndi modafinil samatengedwa nthawi zambiri. Onse armodafinil ndi modafinil ali ndi zinthu zofananira zofananira. Kutenga armodafinil ndi modafinil palimodzi kumawonjezera chiopsezo chazovuta.
Kodi armodafinil iwonetsedwa poyesa mankhwala?
Ayi. Mayeso a mankhwala samakonda kuwunika armodafinil. Armodafinil mulibe amphetamine kotero malingaliro abodza a amphetamine ndi osowa.
Kodi mungatenge armodafinil tsiku lililonse?
Armodafinil imagwira ntchito bwino ikamamwa tsiku lililonse. Ndibwino kuti mutenge mlingo umodzi wa armodafinil nthawi imodzi tsiku lililonse, nthawi zambiri m'mawa.
