Cymbalta vs. Zoloft: Kusiyana, kufanana, ndi zomwe zili zabwino kwa inu
Mankhwala osokoneza bongo Vs. MnzanuKuwunika kwa mankhwala osokoneza bongo & kusiyana kwakukulu | Zinthu zothandizira | Mphamvu | Kuphunzira inshuwaransi ndikufanizira mtengo | Zotsatira zoyipa | Kuyanjana kwa mankhwala | Machenjezo | FAQ
Cymbalta ndi Lexapro ndi mankhwala awiri omwe amagwiritsidwa ntchito kuthana ndi vuto lalikulu la kukhumudwa (MDD) ndi zovuta zina zokhudzana ndi matenda amisala. Matenda okhumudwa, nkhawa, ndi zovuta zina zimakhudza mamiliyoni aku America malinga ndi Nkhawa ndi Kukhumudwa Association of America .
Matenda amisala amakhudza kusinthasintha, zokolola, komanso kuthekera kwa munthu kuthana ndi kupsinjika. Kwa ena, zinthu monga kuchita masewera olimbitsa thupi, kusinkhasinkha, kapena chithandizo chamankhwala zitha kuwapatsa mpumulo, koma kwa ambiri, mankhwala adzafunika kuti athetse vuto lawo. Ngakhale kuti Cymbalta ndi Lexapro amathandizanso pamavuto ambiri ofanana, ndi mankhwala osiyanasiyana, ndipo tikambirana za kusiyana kumeneku.
Kodi pali kusiyana kotani pakati pa Cymbalta ndi Zoloft?
Cymbalta (duloxetine) ndi mankhwala akuchipatala omwe amawonetsedwa pochiza matenda onse okhumudwitsa komanso matenda amisala (GAD). Cymbalta ndi gulu la mankhwala omwe amadziwika kuti serotonin-norepinephrine reuptake inhibitors (SNRIs). Cymbalta imatseka kubwezeretsanso kwa norepinephrine ndi serotonin mu neuronal synapse kusiya serotonin yaulere ndi norepinephrine. Ma neurotransmitters awa amapezeka mosavuta kuti atenge gawo lothandiza pakukhudzidwa komanso kusintha. Ma SNRI ena omwe mungawadziwe ndi Effexor (venlafaxine) ndi Pristiq (desvenlafaxine). Cymbalta imapezeka ngati 20 mg, 30 mg, ndi 60 mg kapisozi wamlomo.
Zoloft (sertraline) ndi mankhwala omwe amathandizidwa ndi MDD. Zoloft amadziwika kuti ndi serotonin reuptake inhibitor yosankha ndipo imagwira ntchito poletsa kubwezeretsanso kwa serotonin kokha pa neuronal synapse. Magulu apamwamba a serotonin omwe amapezeka amapezeka chifukwa cha kusinthasintha kwamaganizidwe ndi mphamvu. Ma SSRI ena omwe mungawadziwe ndi monga Prozac (fluoxetine), Paxil (paroxetine), Celexa (citalopram), ndi Lexapro (escitalopram).
Zoloft imapezeka ngati piritsi yamlomo pamphamvu za 25 mg, 50 mg, ndi 100mg. Ikupezekanso mu yankho lokhazikika pakamwa lomwe ndi 20 mg / ml.
| Kusiyana kwakukulu pakati pa Cymbalta ndi Zoloft | ||
|---|---|---|
| Cymbalta | Zoloft | |
| Gulu la mankhwala osokoneza bongo | Kusankha serotonin norepinephrine reuptake inhibitor | Kusankha serotonin reuptake inhibitor |
| Chizindikiro cha Brand / generic | Zolemba ndi generic zilipo | Zolemba ndi generic zilipo |
| Kodi dzina lachibadwa ndi liti? | Duloxetine | Sertraline |
| Kodi mankhwalawa amabwera mwa mawonekedwe ati? | Makapisozi apakamwa | Mapiritsi apakamwa ndi yankho |
| Kodi mulingo woyenera ndi uti? | 60 mg kamodzi patsiku | 50 mg kamodzi patsiku |
| Kodi mankhwalawa amatenga nthawi yayitali bwanji? | Kutalika (miyezi mpaka zaka) | Kutalika (miyezi mpaka zaka) |
| Ndani amagwiritsa ntchito mankhwalawa? | Achinyamata ndi achikulire | Ana, achinyamata, komanso achikulire |
Zomwe zimachitidwa ndi Cymbalta ndi Zoloft
Cymbalta ndi Zoloft amavomerezedwa kuti athetse vuto lalikulu lachisokonezo, koma mankhwala alionse ali ndi zizindikiro zosiyana. Cymbalta imavomerezedwa kuchiza matenda amisala wamba. Cymbalta imavomerezedwanso kuti ithetse ululu wamitsempha ndi ululu wopweteka. Izi zimapangitsa Cymbalta kupatula mankhwala ena opatsirana pogonana chifukwa ndi okhawo omwe amavomerezedwa ndi matenda opatsirana.
Zoloft imavomerezedwa ndi Food and Drug Administration (FDA) pochiza matenda azisokonezo pagulu komanso matenda osokoneza bongo (OCD). Amagwiritsidwanso ntchito polemba zilembo zamatenda amisala komanso nkhawa yodzipatula. Kugwiritsa ntchito popanda chizindikiro kumawonetsa kuti zomwe akufuna kugwiritsa ntchito sizinavomerezedwe ndi FDA.
Tebulo lazizindikiroli ndilongodziwitsira chabe ndipo siliyenera kukhala upangiri wa zamankhwala. Chonde pitani kwa akatswiri azaumoyo kuti mudziwe chithandizo chomwe chingakuthandizeni.
| Mkhalidwe | Cymbalta | Zoloft |
| Kukhumudwa kwakukulu | Inde | Inde |
| Kuda nkhawa kwakukulu | Inde | Kutumiza |
| Ululu wokhudzana ndi matenda ashuga | Inde | Ayi |
| Ululu wokhudzana ndi fibromyalgia | Inde | Ayi |
| Kupweteka kwaminyewa yaminyewa | Inde | Ayi |
| Kusokonezeka maganizo | Kutumiza | Ayi |
| Matenda amisala | Ayi | Inde |
| Matenda osokoneza bongo | Ayi | Inde |
| Matenda akudzipatula | Ayi | Kutumiza |
| Matenda a Posttraumatic | Ayi | Inde |
| Kusokonezeka kwamantha | Ayi | Kutumiza |
| Kutentha kotentha chifukwa cha kusamba | Ayi | Kutumiza |
| Kuthamangira msanga | Ayi | Kutumiza |
Kodi Cymbalta kapena Zoloft ndi yothandiza kwambiri?
KU kuphunzira lofalitsidwa mu 2016 mwachindunji anafanizira Cymbalta ndi Zoloft pamagwiritsidwe awo othandiza kuthana ndi kukhumudwa, ndipo kafukufukuyu adayang'ana zizindikilo zapadera za kukhumudwa. Ponseponse, mankhwala onsewa adawonetsedwa kuti ndi othandiza kuthana ndi kukhumudwa, pomwe imodzi siyabwino kuposa ina yonse. Komabe, poyang'ana zizindikilo zapadera, mankhwala aliwonse amawoneka kuti ali ndi mwayi wapadera ndi zizindikilo zina. Gulu lomwe limathandizidwa ndi Cymbalta lidawonetsa kusintha kwakukulu pokhudzana ndi kufooka kwa psychomotor, somnolence, komanso kufooka kwa kugonana. Gulu la Zoloft lidawonetsa kusintha kwazizindikiro monga kusokonezeka, nkhawa, ndi hypochondriasis. Onse a Cymbalta ndi Zoloft ndi othandiza kuthana ndi kukhumudwa, koma kafukufukuyu akuwonetsa kuti omwe akuyitanitsa ayenera kusamala kwambiri za zizindikiritso za munthu posankha mankhwala.
Kuphunzira ndi kuyerekezera mtengo wa Cymbalta vs. Zoloft
Cymbalta ndi mankhwala omwe amapatsidwa ndi mankhwala komanso mankhwala a Medicare. Mtengo wamthumba wa Cymbalta 60 mg utha kukhala wopitilira $ 300, koma ndi coupon yochokera ku SingleCare, mutha kupeza generic yotsika $ 15 kuma pharmacies omwe akutenga nawo mbali.
Zoloft ndi mankhwala omwe amalembedwa ndi Medicare komanso mapulani azamalonda. Mtengo wapa thumba wa dzina lake Zoloft utha kukhala wopitilira $ 400, koma mutha kugwiritsa ntchito coupon kuchokera ku SingleCare kuti mupeze mtundu wa $ 10.
Pezani khadi yotsitsa ya SingleCare
| Cymbalta | Zoloft | |
| Nthawi zambiri amakhala ndi inshuwaransi? | Inde | Inde |
| Nthawi zambiri amakhala ndi Medicare Part D? | Inde | Inde |
| Mlingo woyenera | 30, 60 mg makapisozi | 30, 50 mg mapiritsi |
| Wopanga Medicare wamba | Osakwana $ 10 | Osakwana $ 10 |
| Mtengo wosakwatiwa | $ 15 + | $ 10 + |
Zotsatira zoyipa za Cymbalta vs. Zoloft
Cymbalta ndi Zoloft onse amadziwika kuti amachititsa kusokonezeka m'mimba monga nseru, kutsegula m'mimba, ndi kudzimbidwa. Nausea ndi gawo lofala kwambiri pamankhwala onsewa ndipo limatha kusintha moyo. Ngati mukumva nseru zomwe zikukhudza zochitika zanu za tsiku ndi tsiku, muyenera kudziwitsa omwe adakulemberani.
Kupweteka, kapena kugona kwambiri kapena kugona, ndichimodzi mwazovuta za Cymbalta ndi Zoloft. Odwala omwe amatenga Cymbalta amathanso kumva kupweteka mutu komanso kuthamanga kwa magazi. Cymbalta, komabe, sikuwoneka kuti ikukhudza libido, pomwe kugwiritsa ntchito Zoloft kutero.
Tebulo ili siliyenera kukhala mndandanda wathunthu wazotsatira zoyipa zomwe zingachitike ndipo ndizongodziwitsa chabe. Chonde funsani akatswiri azaumoyo kuti mumve mndandanda wathunthu.
| Cymbalta | Zoloft | |||
| Zotsatira zoyipa | Zoyenera? | Pafupipafupi | Zoyenera? | Pafupipafupi |
| Nseru | Inde | 2. 3% | Inde | 26% |
| Pakamwa pouma | Inde | 13% | Inde | 14% |
| Kutuluka thukuta | Inde | 6% | Inde | 7% |
| Kutsekula m'mimba | Inde | 9% | Inde | 4% |
| Kudzimbidwa | Inde | 9% | Inde | 6% |
| Dyspepsia | Ayi | n / A | Inde | 8% |
| Chizungulire | Inde | 9% | Inde | 12% |
| Kusinza | Inde | 10% | Inde | khumi ndi chimodzi% |
| Mutu | Inde | 14% | Ayi | n / A |
| Kuchuluka kwa magazi | Inde | awiri% | Ayi | n / A |
| Kuchepetsa chilakolako | Inde | 7% | Inde | 3% |
| Kuchepetsa libido | Ayi | n / A | Inde | 6% |
Gwero: Cymbalta ( Tsiku ndi Tsiku Zoloft ( Tsiku ndi Tsiku )
Kuyanjana kwa mankhwala a Cymbalta vs. Zoloft
Cymbalta ndi Zoloft amagawana zochitika zina zomwe zimagwiritsidwa ntchito ndi mankhwala, koma pali zina zomwe zimafotokozedwanso pamankhwala aliwonse. Cymbalta imaletsa CYP2D6, enzyme yomwe imayambitsa kagayidwe ka mankhwala ambiri kuphatikiza mankhwala okhudzana ndi amphetamine. Amphetamines amagwiritsidwa ntchito pochiza matenda osowa chidwi, omwe amathanso kupezeka kwa odwala omwe ali ndi nkhawa kapena nkhawa. Kuletsa kwa cymbalta kwa enzyme iyi kumatha kubweretsa kuchuluka kwama amphetamines m'magazi. Odwala omwe ali pamitundu yonse iwiri ya mankhwala ayenera kuyang'aniridwa mosamala.
Cymbalta ndi Zoloft amatha kuyambitsa matenda a serotonin akaphatikizidwa ndi mankhwala ena okhala ndi serotonergic. Matenda a Serotonin ndi zotsatira za kuchuluka kwa serotonin yaulere ndipo imatha kubweretsa kusokonezeka, chizungulire, komanso kugunda kwa mtima. Mankhwala monga migraine eletriptan kapena chowonjezera cha St. John's Wort chingayambitse kulumikizanaku.
Zoloft imatha kuyambitsa mtundu wina wamatenda amtima omwe amadziwika kuti nthawi yayitali ya QTc akamamwa mankhwala ena. Ndikofunikira kuti katswiri wanu wamankhwala komanso wamankhwala azikhala ndi mndandanda wathunthu wamankhwala omwe mukumwa kuti muwone moyenera mayankho omwe mungachitike.
Mndandanda wotsatirawu sikuti ukhale mndandanda wathunthu wamagwiritsidwe azamankhwala. Dokotala wanu kapena wamankhwala atha kupereka mndandanda wathunthu.
| Mankhwala osokoneza bongo | Gulu la mankhwala osokoneza bongo | Cymbalta | Lexapro |
| Almotriptan Eletriptan Oxitriptan | 5HT Agonist / Triptans (othandizira ma antimigraine) | Inde | Inde |
| Amphetamine mchere Dexmethylphenidate Methylphenidate | Amphetamine | Inde | Inde |
| Alosetron Ondansetron Ramosetron | Otsutsa a 5HT3 (odana ndi nseru) | Ayi | Inde |
| Aripiprazole | Mankhwala oletsa antipsychotic | Inde | Inde |
| Asipilini Zamgululi Naproxen Diclofenac | Mankhwala osagwiritsidwa ntchito poletsa kutupa (NSAIDs) | Inde | Inde |
| Enoxaparin Heparin | Maantibayotiki | Ayi | Inde |
| Buspirone | Kuda nkhawa | Inde | Inde |
| Carbamazepine | Wosakanikirana | Ayi | Inde |
| Esomeprazole Omeprazole | Proton pump inhibitor | Ayi | Inde |
| Fluconazole | Zosakanikirana | Ayi | Inde |
| Fluoxetine Citalopram Paroxetine Kuyanjana | SSRIs | Inde | Inde |
| Hydroxychloroquine | Aminoquinolone / Antimalarial | Ayi | Inde |
| Mzere | Maantibayotiki | Inde | Inde |
| Metaxalone | Opumitsa minofu | Inde | Inde |
| Pimozide | Mankhwala oletsa antipsychotic | Ayi | Inde |
| Selegiline Phenelzine Rasagiline | Monoamine oxidase inhibitor (MAOI) | Inde | Inde |
| St. John's Wort | Mankhwala owonjezera azitsamba | Inde | Inde |
| Hydrochlorothiazide Chlorthalidone Metolazone | Odzetsa okodzetsa | Ayi | Inde |
| Zamgululi | Opiate ochepetsa ululu | Inde | Inde |
| Amitriptyline Clomipramine Doxepin Mzere wa Nortriptyline | Tricyclic antidepressants | Inde | Inde |
Machenjezo a Cymbalta ndi Zoloft
Ndikofunika kumvetsetsa kuti ngakhale Cymbalta kapena Zoloft sizingabweretse kuchotseredwa kwazizindikiro zamatenda amisala kapena nkhawa. Zitenga masabata osachepera awiri kuti muone kusintha kulikonse kwa odwala ambiri, komanso mpaka milungu inayi mpaka isanu ndi umodzi kuti muzindikire zotsatira zake. Osasiya msanga mankhwala anu ndikukhulupirira kuti sikugwira ntchito musanalankhule ndi omwe anakupatsani.
Odwala omwe ali ndi MDD atha kukhala ndi vuto lakukhumudwa kapena malingaliro ofuna kudzipha ngati akumwa kapena ayi. Izi zitha kukulirakulira mpaka kukhululukidwa kukwaniritsidwa. Chithandizo cha Cymbalta ndi Zoloft chitha kukulitsa malingaliro ofuna kudzipha pakati pa achinyamata ndi achinyamata, makamaka kumayambiriro kwa chithandizo. Odwalawa ayenera kuyang'aniridwa mosamala ngati mankhwalawa akuwoneka kuti ndi ofunikira. Kusintha kwa mankhwala kungakhale kofunikira ngati zizindikiro zadzidzimuka kapena zikukula.
Pakhala pali malipoti a kulephera kwa chiwindi, nthawi zina amapha, ndi Cymbalta. Milanduyi imatha kubwera ndikumva kupweteka m'mimba komanso michere yayikulu ya chiwindi yokhala ndi jaundice kapena yopanda. Kumwa mowa kumatha kuwonjezera ngoziyi, chifukwa chake kuyenera kupewedwa.
Zoloft imatha kuyambitsa mtundu wina wamatenda amtima omwe amadziwika kuti nthawi yayitali ya QTc akamamwa mankhwala ena. Ndikofunikira kuti katswiri wanu wamankhwala komanso wamankhwala azikhala ndi mndandanda wathunthu wamankhwala omwe mukumwa kuti muwone moyenera mayankho omwe mungachitike. Chonde funsani chithandizo chamankhwala kuchokera kwa omwe amakuthandizani asanayambe njira zochiritsira zatsopano.
Matenda a Serotonin adanenedwa ndi ma SSRIs onse ndi ma SNRIs, kuphatikiza Cymbalta ndi Zoloft. Izi ndizomwe zimakhudzana ndi kuchuluka kwa serotonin ndipo zimatha kupangitsa wodwalayo kukhala wamanjenje, wamisala, komanso kuwonjezeka kwa mtima.
Mafunso omwe amafunsidwa kawirikawiri za Cymbalta vs. Zoloft
Kodi Cymbalta ndi chiyani?
Cymbalta (Cymbalta ndi chiyani?) Ndi mankhwala olepheretsa kupanikizika omwe amagwiritsidwa ntchito pochiza kukhumudwa kwakukulu, matenda amisala wamba, ndi matenda osiyanasiyana am'mapapo ndi mafupa. Cymbalta ili mgulu la mankhwala omwe amadziwika kuti serotonin-norepinephrine reuptake inhibitors (SNRIs). Cymbalta imapezeka ngati kapisozi wamlomo mu 20 mg, 30 mg, ndi 60 mg mphamvu.
Kodi Zoloft ndi chiyani?
Zoloft (Zoloft ndi chiyani?) Ndi mankhwala omwe amagwiritsidwa ntchito pochiza matenda osokoneza bongo komanso mavuto ena amisala. Zoloft ali mgulu la mankhwala omwe amadziwika kuti serotonin reuptake inhibitors (SSRIs). Zoloft imapezeka ngati mapiritsi apakamwa mu 25 mg, 50 mg, ndi mphamvu za 100 mg, komanso kusungunuka kwamadzi am'kamwa.
Kodi Cymbalta ndi Zoloft ndizofanana?
Ngakhale onse a Cymbalta ndi Zoloft amathandizira kukhumudwa ndi matenda amisala osiyanasiyana, siamtundu womwewo wa mankhwala. Cymbalta ili m'gulu la mankhwala omwe amadziwika kuti serotonin-norepinephrine reuptake inhibitors (SNRIs), ndipo imawonjezera kuchuluka kwa serotonin ndi norepinephrine. Zoloft ali mgulu la mankhwala omwe amadziwika kuti serotonin reuptake inhibitors (SSRIs) ndipo amachititsa kuchuluka kwa serotonin komwe kulipo.
Kodi Cymbalta kapena Zoloft ndibwino?
Cymbalta ndi Zoloft ali ofanana ndi kuthekera kwawo kuthana ndi kukhumudwa. Cymbalta ili ndi chisonyezero chowonjezera cha nkhawa yayikulu. Ndikofunika kuyang'ana pazizindikiro zakukhumudwa komanso zovuta zina posankha mankhwala omwe angakhale abwino kwa wodwala wina.
Kodi ndingagwiritse ntchito Cymbalta kapena Zoloft ndili ndi pakati?
A FDA amatenga onse awiri a Cymbalta ndi Lexapro (omwe ndi Lexapro) omwe ali ndi pakati C, kutanthauza kuti sipanakhale maphunziro okwanira aanthu kuti athetse chitetezo. Ndi Cymbalta, zotsatira zosakhala za teratogenic zawonedwa mwa ana akhanda kutsatira kuyang'anira kwa Cymbalta ali ndi pakati. Izi zimaphatikizapo kupuma, kupuma movutikira, ndi kunjenjemera. Mwambiri, mankhwala aliwonse ayenera kugwiritsidwa ntchito pokhapokha phindu kwa mayi limaposa chiopsezo cha mwana wosabadwayo.
Kodi ndingagwiritse ntchito Cymbalta kapena Zoloft ndi mowa?
Odwala ayenera kupewa kumwa kwambiri ngati atenga Cymbalta kapena Zoloft. Mowa umatha kuwonjezera zotsatira zoyipa zamankhwala onsewa ndipo utha kuyambitsa kuwonongeka kwakukulu kwama psychomotor. Ndi Cymbalta makamaka, mowa umachulukitsa kuchepa kwa chiwindi.
Kodi ndi antidepressant iti yabwino yomwe imakhala ndi zovuta zochepa?
Mankhwala ochepetsa nkhawa pamsika ku United States akhala akuyesedwa mokwanira kuti awonetsetse kuti ndi othandiza kuthana ndi kukhumudwa. Zonsezi zimakhala ndi zovuta zomwe zimachitika mosiyanasiyana. Dokotala wanu adzawona zizindikiro zanu zakukhumudwa komanso zovuta zomwe zimakukhudzani kwambiri posankha mankhwala.
Kodi Zoloft amakukhudzani pogonana?
Wopanga akuti pafupifupi 6% ya odwala atha kuchepa ndi libido, kapena kutsika pagalimoto, akamatenga Cymbalta. Odwala omwe akukumana ndi izi ayenera kulankhula ndi akatswiri awo azaumoyo za njira zina.
Zomwe zili bwino: Prozac kapena Zoloft?
Pali deta kunena kuti Zoloft atha kukhala wopambana kuposa Prozac (Prozac ndi chiyani) potengera mphamvu yake pochiza kukhumudwa. Komabe, olemba mankhwalawa adzaganizira zinthu zambiri posankha mankhwala. Ndi dokotala wanu yekhayo amene angasankhe zomwe zingakhale zoyenera kwa inu.
