Ozempic vs. Trulicity: Kusiyana, kufanana, ndi zomwe zili zabwino kwa inu
Mankhwala osokoneza bongo Vs. MnzanuKuwunika kwa mankhwala osokoneza bongo & kusiyana kwakukulu | Zinthu zothandizira | Mphamvu | Kuphunzira inshuwaransi ndikufanizira mtengo | Zotsatira zoyipa | Kuyanjana kwa mankhwala | Machenjezo | FAQ
Ngati muli ndi matenda ashuga amtundu wa 2, endocrinologist wanu kapena wothandizira zaumoyo woyamba atha kugwiritsa ntchito mankhwala ojambulidwa kuti muchepetse shuga wanu wamagazi. Ozempic (semaglutide) ndi Trulicity (dulaglutide) ndi mankhwala awiri ojambulidwa omwe amagwiritsidwa ntchito pochiza matenda amtundu wa 2. Ozempic amapangidwa ndi Novo Nordisk, ndipo Trulicity imapangidwa ndi Eli Lilly ndi Company. Mankhwala onsewa amavomerezedwa ndi FDA. Amagawidwa mgulu la mankhwala otchedwa GLP-1 receptor agonists (glucagon-ngati peptide agonists).
Ozempic ndi Trulicity ndi mankhwala ojambulidwa ndi matenda ashuga - koma ayi insulini . Amagwira ntchito polimbikitsa kutsekemera kwa insulin ndikuchepetsa kutsekemera kwa glucagon, potero amachepetsa magazi m'magazi. Mankhwalawa amachepetsanso pang'ono kutulutsa m'mimba, komwe kumathandizira kuchepetsa kudya komanso pambuyo pobereka (pambuyo pakudya) shuga m'magazi. Amathandizira kuchepetsa thupi pothandiza kuchepetsa thupi.
Ozempic ndi Trulicity amathandizanso kuchepetsa hemoglobin A1c (HbA1c), komwe kumayesa kuwongolera kwa nthawi yayitali. Ngakhale mankhwala onsewa ndi agonists a GLP-1, ali ndi zosiyana, zomwe tikambirana pansipa.
Kodi pali kusiyana kotani pakati pa Ozempic ndi Trulicity?
Ozempic ndi Trulicity ali mgulu la mankhwala lotchedwa GLP-1 agonists, kapena glucagon-ngati peptide agonists. Mankhwala onsewa amapezeka muzina lokha. Chogwiritsira ntchito mu Ozempic ndi semaglutide, ndipo chinthu chogwira ntchito mu Trulicity ndi dulaglutide. Komabe, palibe mankhwala omwe alipo pakadali pano mwanjira yachibadwa. Mankhwala onsewa amapezeka mu fomu yopangira jekeseni. Ndi mulingo uliwonse sabata iliyonse, mankhwalawa amalowetsedwa m'mimba, ntchafu, kapena mkono wapamwamba.
| Kusiyana kwakukulu pakati pa Ozempic ndi Trulicity | ||
|---|---|---|
| Ozempic | Kutuluka | |
| Gulu la mankhwala osokoneza bongo | Glucagon ngati peptide 1 (GLP-1) receptor agonist | Glucagon ngati peptide 1 (GLP-1) receptor agonist |
| Chizindikiro cha Brand / generic | Mtundu | Mtundu |
| Kodi dzina lachibadwa ndi liti? | Semaglutide | Dulaglutide |
| Kodi mankhwalawa amabwera mwa mawonekedwe ati? | Jekeseni ya pensi ya jakisoni wochepera | Jekeseni ya pensi ya jakisoni wochepera |
| Kodi mulingo woyenera ndi uti? | Mlingo woyambira: 0.25 mg kamodzi sabata iliyonse. Pambuyo pa masabata 4, wonjezerani mlingo wa 0,5 mg kamodzi pa sabata. Atha kuchuluka mpaka 1 mg kamodzi sabata iliyonse pakatha milungu inayi ngati pakufunika kuwonjezerapo glycemic control. Mlingo woyenera kwambiri ndi 1 mg sabata iliyonse | Mlingo woyambira: 0.75 mg kamodzi sabata iliyonse. Atha kuchuluka mpaka 1.5 mg kamodzi sabata iliyonse ngati kulimbikitsidwa kowonjezera kwa glycemic pakufunika. Mlingo woyenera kwambiri ndi 1.5 mg kamodzi pamlungu |
| Kodi mankhwalawa amatenga nthawi yayitali bwanji? | Zimasintha | Zimasintha |
| Ndani amagwiritsa ntchito mankhwalawa? | Akuluakulu azaka 18 kapena kupitilira apo | Akuluakulu azaka 18 kapena kupitilira apo |
Mukufuna mtengo wabwino kwambiri pa Trulicity?
Lowani zidziwitso zamitengo ya Trulicity ndikupeza kuti mitengo ikasintha liti!
Pezani zidziwitso zamitengo
Zomwe zimathandizidwa ndi Ozempic ndi Trulicity
Onse Ozempic ndi Trulicity ali ndi ziwonetsero ziwiri. Chizindikiro choyamba ndi kukonza kuwongolera kwa glycemic mwa akulu omwe ali ndi matenda amtundu wa 2 (molumikizana ndi zakudya ndi masewera olimbitsa thupi). Chizindikiro chachiwiri ndikuchepetsa chiopsezo cha zochitika zazikulu zamtima (stroke, matenda amtima, kufa kwamtima) mwa odwala omwe ali ndi Type 2 shuga ndi matenda amtima.
| Mkhalidwe | Ozempic | Kutuluka |
| Phatikizani ndi zakudya ndi masewera olimbitsa thupi kuti muchepetse kuwongolera kwa glycemic mwa akulu omwe ali ndi Type 2 diabetes mellitus (DM) | Inde | Inde |
| Kuchepetsa chiopsezo cha zovuta zazikulu zam'mimba mwa akulu omwe ali ndi Type 2 DM ndimatenda amtima | Inde | Inde |
Kodi Ozempic kapena Trulicity ndiyothandiza kwambiri?
Mu gawo 3b mayesero azachipatala . Komabe, ndikofunikira kudziwa kuti kafukufukuyu adachitidwa ndi Novo Nordisk, wopanga Ozempic. Palibe maphunziro ena am'mutu ndi mutu omwe adachitika poyerekeza Ozempic ndi Trulicity.
Mankhwala othandiza kwambiri kwa inu amatsimikiziridwa bwino ndi endocrinologist wanu kapena wothandizira zaumoyo, yemwe angaganizire zaumoyo wanu komanso mbiri yazachipatala, komanso mankhwala ena omwe mumamwa.
Kuphunzira ndi kuyerekezera mtengo wa Ozempic vs. Trulicity
Zonse za Ozempic ndi Trulicity zimaphimbidwa ndi inshuwaransi yambiri komanso mapulani a Medicare Part D. Funsani ndi omwe amakupatsirani inshuwaransi kuti mumve zambiri / zolipitsa dongosolo lanu.
Mankhwala a Ozempic pafupifupi $ 970. Mutha kugula kwa $ 711 ndi coupon ya SingleCare Ozempic kuchotsera.
Mankhwala a Trulicity amatha kuthamanga pafupifupi $ 2,000. Mutha kusunga ndi SingleCare ndikulipira $ 1,432 kuma pharmacies omwe akutenga nawo mbali.
| Ozempic | Kutuluka | |
| Nthawi zambiri amakhala ndi inshuwaransi? | Inde (kawirikawiri) | Inde (kawirikawiri) |
| Nthawi zambiri amakhala ndi Medicare Part D? | Inde (kawirikawiri) | Inde (kawirikawiri) |
| Mlingo woyenera | 1 cholembera chodziwika bwino (imapereka 0.25 mg, 0.5 mg, kapena 1 mg pa jakisoni) | Bokosi limodzi la 4, zolembera zamtundu umodzi (0.75 mg kapena 1.5 mg pa jekeseni wa 0.5 ml) |
| Chitsanzo cha Medicare Part D copay | $ 25- $ 888 | $ 25- $ 873 |
| Mtengo wosakwatiwa | $ 711 | $ 1,432 |
Zotsatira zoyipa za Ozempic vs. Trulicity
Zotsatira zoyipa kwambiri za Ozempic ndi nseru, kusanza, kutsegula m'mimba, kupweteka m'mimba, ndi kudzimbidwa. Zotsatira zoyipa kwambiri za Trulicity ndi nseru, kusanza, kutsegula m'mimba, kupweteka m'mimba, kudzimbidwa, kuchepa kwa njala, kutopa, ndi kudzimbidwa. Hypoglycemia (shuga wotsika magazi) imatha kuchitika ndi mankhwala. Ili si mndandanda wathunthu wazotsatira. Zotsatira zina zoyipa zimatha kuchitika. Funsani wothandizira zaumoyo wanu kuti mupeze mndandanda wa zotsatirapo zake.
| Ozempic | Kutuluka | |||
| Zotsatira zoyipa | Zoyenera? | Pafupipafupi | Zoyenera? | Pafupipafupi |
| Nseru | Inde | 15.8-20.3% * | Inde | 12.4-21.1% * |
| Kusanza | Inde | 5.0-9.2% | Inde | 6.0-12.7% |
| Kutsekula m'mimba | Inde | 8.5-8.8% | Inde | 8.9-12.6% |
| Kupweteka m'mimba | Inde | 5.7-7.3% | Inde | 6.5-9.4% |
| Kudzimbidwa | Inde | 3.1-5.0% | Inde | 3.7-3.9% |
| Hypoglycemia (shuga wotsika magazi) | Inde | Zimasintha | Inde | Zimasintha |
| Kuchepetsa chilakolako | Inde | % sananene | Inde | 4.9-8.6% |
| Kutopa | Inde | > 0.4% | Inde | 4.2-5.6% |
| Dyspepsia (kudzimbidwa) | Inde | 2.7-3.5% | Inde | 4.1-5.8% |
* Zimadalira mlingo
Gwero: DailyMed ( Ozempic ), Tsiku Lililonse ( Kutuluka ).
Kuyanjana kwa mankhwala a Ozempic vs. Trulicity
Kugwiritsa ntchito Ozempic kapena Trulicity ndi insulin kapena insulin secretagogues (mankhwala ena ashuga am'kamwa) kumatha kuwonjezera ngozi ya hypoglycemia. Mukamamwa mankhwala osakaniza awa, woyimilirayo atha kusintha kusintha kwa insulin kapena mankhwala akumwa. Komanso, chifukwa Ozempic kapena Trulicity imachedwetsa kutaya kwa m'mimba, kuyamwa kwa mankhwala akumwa kumatha kukhudzidwa ngati kungatenge nthawi yomweyo. M'maphunziro, kulumikizana kumeneku sikunachitike kwenikweni; Komabe, ndibwino kuti mufunsane ndi omwe amakuthandizani pazanthawi yanu yamankhwala.
Mankhwala omwe ali ndi ndandanda yocheperako amayenera kuyang'aniridwa makamaka. Izi zimaphatikizapo mankhwala osokoneza bongo pomwe pali zenera laling'ono pakati pazithandizo ndi poizoni monga Coumadin (warfarin), Lanoxin (digoxin), ndi mankhwala olanda.
Ili si mndandanda wathunthu wazomwe zimachitika ndi mankhwala. Funsani wothandizira zaumoyo wanu kuti mupeze mndandanda wathunthu wamagwiridwe antchito.
| Mankhwala osokoneza bongo | Gulu la mankhwala osokoneza bongo | Ozempic | Kutuluka |
| Meglitinides (gulu, repaglinide) Sulfonylureas (glimepiride, glipizide, glyburide) | Kubisa kwa insulin | Inde | Inde |
| Basaglar Zolemba Lantus Levemir Novolog Toujeo Tresiba | Insulini | Inde | Inde |
| Mankhwala apakamwa | Mankhwala apakamwa | Inde (mwina) | Inde (mwina) |
Machenjezo a Ozempic ndi Trulicity
Chifukwa mankhwala onsewa ali mgulu limodzi la mankhwala, machenjezo ndi zodzitetezera ndizofanana. Mukalandira chitsogozo cha mankhwala nthawi iliyonse mukadzaza mankhwala a Ozempic kapena Trulicity, omwe amapitilira zoyipa ndi machenjezo.
Pali chenjezo la bokosi la Ozempic ndi Trulicity, lomwe ndi chenjezo lalikulu lomwe a FDA amafunikira. Mu makoswe, Ozempic kapena Trulicity imayambitsa zotupa za C-cell, kuphatikiza MTC (medullary thyroid carcinoma). Sizikudziwika ngati izi zimachitika mwa anthu. Komanso, odwala omwe ali ndi mbiri (kapena mbiri yabanja) ya MTC kapena omwe ali ndi endocrine neoplasia syndrome mtundu wa 2 (MEN 2) sayenera kutenga Ozempic kapena Trulicity.
Machenjezo ena ndi awa:
- Pachimake kapamba kumachitika. Odwala amayenera kuyang'aniridwa mosamala pazizindikiro za kapamba, kuphatikiza kupweteka kwam'mimba kosalekeza, komwe kumatha kutuluka kumbuyo, ndipo mwina kumatha kusanza. Ngati mukukayikira kuti kapamba amayamba chifukwa cha kapamba, Ozempic kapena Trulicity ayenera kuyimitsidwa ndikuwunika koyenera. Ngati kapamba katsimikiziridwa, mankhwalawa sayenera kuyambiranso.
- Matenda a shuga omwe angayambitsenso matenda a shuga amatha kuchitika-chiopsezo chimakhala chachikulu kwa odwala omwe ali ndi mbiri yokhudzana ndi matenda ashuga. Kuwongolera mwachangu kwa kuwongolera shuga m'magazi kumatha kuphatikizidwa ndi kukulirakulira kwakanthawi kwa matenda ashuga. Odwala ayenera kuyang'aniridwa.
- Zolembera za Ozempic kapena Trulicity siziyenera kugawidwa pakati pa odwala, ngakhale singano itasinthidwa, chifukwa cha chiwopsezo chowonjezereka chofalitsira tizilombo toyambitsa matenda. Zolembera za Trulicity ndi zolembera zogwiritsa ntchito kamodzi-cholembera chilichonse chogwiritsa ntchito katatu chimagwiritsidwa ntchito kamodzi.
- Shuga wamagazi ochepa amatha kupezeka Ozempic kapena Trulicity akamamwa mankhwala a insulin kapena insulin secretagogue. Kusintha kwa insulin kapena insulin secretagogue kungafunike.
- Kuvulala koopsa kwa impso komanso kuwonongeka kwa impso kosatha kumatha kuchitika, komwe kungafune dialysis. Zizindikiro zimatha kukhala ndi nseru, kusanza, kutsegula m'mimba, ndi / kapena kuchepa madzi m'thupi. Ntchito ya impso iyenera kuyang'aniridwa.
- Zochitika zazikulu za hypersensitivity (anaphylaxis kapena angioedema) zafotokozedwa. Izi zikachitika, Ozempic kapena Trulicity ayenera kusiya. Odwala omwe kale anali ndi hypersensitivity reaction sayenera kugwiritsa ntchito Ozempic kapena Trulicity.
- Chifukwa choopsa kwa mwana wosabadwayo, Ozempic kapena Trulicity nthawi zambiri sayenera kugwiritsidwa ntchito pathupi, pokhapokha phindu litaposa ngozi. Wopereka chithandizo chamankhwala atha kupeza mankhwala enanso osagwiritsidwa ntchito.
- Kuphatikiza apo, chidziwitso cha wopanga Trulicity chimati mankhwalawa atha kuphatikizidwa ndi zomwe zimachitika m'mimba (GI), nthawi zina zimakhala zovuta. Chifukwa Trulicity sinaphunzirepo kwa odwala omwe ali ndi matenda oopsa a GI, kuphatikiza gastroparesis yayikulu, sizoyenera kugwiritsidwa ntchito mwa odwalawa.
Mafunso omwe amafunsidwa pafupipafupi okhudza Ozempic vs. Trulicity
Kodi Ozempic ndi chiyani?
Ozempic ndi mankhwala omwe amalowa kamodzi kamodzi sabata iliyonse pochiza matenda amtundu wa Type 2. Amadziwika kuti GLP-1 receptor agonist.
Kodi Trulicity ndi chiyani?
Trulicity ndi jakisoni kamodzi kamodzi pamlungu wothandizira mtundu wa 2 shuga. Ndi GLP-1 receptor agonist.
Kodi Ozempic ndi Trulicity ndizofanana?
Ozempic ndi Trulicity onse ali mgulu la mankhwala lotchedwa GLP-1 receptor agonists. Ndizofanana, koma sizofanana kwenikweni. Zomwe zili pamwambazi zimafotokoza mwatsatanetsatane za mankhwala aliwonse. Mankhwala ena omwe ali mgulu la GLP-1 receptor agonist ndi a Victoza (liraglutide), Byetta (exenatide), Bydureon (exenatide yotulutsidwa), ndi Adlyxin (lixisenatide). Palinso piritsi la semaglutide lomwe limapezeka, lokhala ndi zomwezi mu Ozempic. Piritsi lomwelo limatchedwa Rybelsus.
Kodi Ozempic kapena Trulicity ndibwino?
Mankhwala onsewa akuwoneka ngati ofanana pamagwiridwe antchito a glycemic control ndikuthandizira kuchepetsa kunenepa. Kafukufuku wina (onani pamwambapa) anayerekezera mankhwala awiriwo ndipo anapeza Ozempic kukhala yabwinoko pang'ono. Koma ndikofunikira kuzindikira kuti kafukufukuyu adachitika ndi wopanga Ozempic. Funsani omwe amakuthandizani kuti muwone ngati Ozempic kapena Trulicity ingakhale mankhwala oyenera kwa inu.
Kodi ndingagwiritse ntchito Ozempic kapena Trulicity ndili ndi pakati?
Pali zochepa pa Ozempic ndi Trulicity ali ndi pakati. Zitha kupweteketsa mwana. Funsani omwe akukuthandizani kuti akuthandizeni. Ngati mukumwa kale Ozempic kapena Trulicity ndikupeza kuti muli ndi pakati, lemberani OB-GYN mwachangu kuti akutsogolereni.
Kodi ndingagwiritse ntchito Ozempic kapena Trulicity ndi mowa?
Ndikofunika kupewa mowa mukamagwiritsa ntchito Ozempic kapena Trulicity. Mowa ungayambitsenso shuga m'magazi, ndipo Ozempic kapena Trulicity amathanso kuyambitsa shuga wotsika magazi. Kuphatikizana kungayambitse shuga wotsika kwambiri kapena wautali.
Kodi Ozempic ndiyofanana ndi metformin?
Ayi jekeseni wa Ozempic kapena mankhwala am'thupi a metformin atha kugwiritsidwa ntchito limodzi ndi insulin komanso / kapena mankhwala ena am'kamwa, komanso zakudya ndi masewera olimbitsa thupi, pochiza matenda amtundu wa Type 2. (Ozempic sinafotokozedwe pochiza matenda ashuga amtundu wa 1 kapena pochiza matenda ashuga ketoacidosis).
Zimatenga nthawi yayitali bwanji kuti Ozempic ayambe kugwira ntchito?
Mukabaya Ozempic, kuchuluka kwake kumafika tsiku limodzi kapena atatu. Komabe, zimatha kutenga nthawi kuti muwone zotsatira zake. Mlingo wofala kwambiri ndikuyamba pa 0.25 mg kamodzi pa sabata ndipo pakatha milungu inayi, mukulitsa mlingo mpaka 0.5 mg kamodzi pa sabata. Ngati patatha milungu inayi, mukufunika kuwongolera, mudzawonjezeka mpaka 1 mg kamodzi pa sabata. Wothandizira zaumoyo wanu adzakutsogolerani pamlingo woyenera.
Kodi Ozempic imayambitsa nkhawa?
Ozempic zambiri za wopanga sichikutchula nkhawa ngati zoyipa zina. Komabe, Ozempic imatha kuyambitsa hypoglycemia (shuga wotsika magazi), ndipo kuda nkhawa kumatha kukhala chimodzi mwazizindikiro za shuga wotsika magazi. Ngati muli pa Ozempic ndipo muli ndi nkhawa zomwe simunakumanepo nazo, funsani omwe akukuthandizani.
