Zyban vs. Chantix: Kusiyana, kufanana ndi zomwe zili zabwino kwa inu
Mankhwala osokoneza bongo Vs. MnzanuKuwunika kwa mankhwala osokoneza bongo & kusiyana kwakukulu | Zinthu zothandizira | Mphamvu | Kuphunzira inshuwaransi ndi kufananiza mtengo | Zotsatira zoyipa | Kuyanjana kwa mankhwala | Machenjezo | FAQ
Phindu la kusiya kusuta ndilochuluka. Kuchepetsa kuthamanga kwa magazi ndi kugunda kwa mtima kumabwera nthawi yomweyo ndipo chiopsezo chodwala matenda a mtima chimachepa pakangodutsa maola 24. Kuphatikiza apo, cholesterol ikhala bwino, chiopsezo cha khansa chimachepa ndipo chitetezo chamthupi ndi mafupa anu zimalimba.
Nthawi zina mumafunikira thandizo lina kusiya, ndipo mankhwala akuchipatala angakuthandizeni. Mankhwala awiri omwe amalembedwa pakutha kwa kusuta ndi Zyban (bupropion Hcl Er) ndi Chantix. Mankhwala onsewa amavomerezedwa ndi US Food and Drug Administration (FDA) ndipo amagwiritsidwa ntchito kuthandiza odwala omwe amasiya kusuta, koma amagwira ntchito m'njira zosiyanasiyana ndipo amakhala ndi zovuta zina.
Kodi pali kusiyana kotani pakati pa Zyban ndi Chantix?
Zyban (bupropion Hcl Er) imapezeka mu generic, monga mapiritsi otulutsa 150 mg. Zyban sichikupezeka mu dzina la dzina; idapangidwa koyamba ndi GlaxoSmithKline. Amagwiritsidwa ntchito kwa odwala 14 kapena kupitilira apo; odwala ayeneranso kulemera osachepera 89 lbs. Zyban imayambika sabata imodzi tsiku loti munthu asute, ndipo amamutenga milungu 7-12, pafupifupi.
Chantix (varenicline) imapezeka mu dzina lokha, monga mapiritsi a 0.5 mg ndi 1 mg, ndipo amapangidwa ndi kampani ya mankhwala Pfizer. Chantix, yomwe imagwiritsidwa ntchito mwa akulu okha, imayambika sabata imodzi tsiku loti munthu asiye kusuta litenge ndipo amatengedwa milungu 12; odwala atha kupitilirabe kwa milungu ina 12 ngati nthawi yoyamba ikuyenda bwino.
| Kusiyana kwakukulu pakati pa Zyban ndi Chantix | ||
|---|---|---|
| Chantix | Zyban | |
| Gulu la mankhwala osokoneza bongo | Aminoketone antidepressant, kusuta fodya kuthandizira | Nicotinic agonist, thandizo losiya kusuta |
| Chizindikiro cha Brand / generic | Zowonjezera | Mtundu |
| Kodi dzina lachibadwa ndi liti? | Bupropion | Mzere |
| Kodi mankhwalawa amabwera mwa mawonekedwe ati? | Pulogalamu yotulutsidwa | Mapiritsi |
| Kodi mulingo woyenera ndi uti? | Yambani sabata limodzi musanasiye kusuta: 150 mg tsiku lililonse masiku atatu, kenako 150 mg kawiri patsiku (osachepera maola 8 osiyanasiya) pambuyo pake | Yambani sabata limodzi musanasiye kusuta: 0.5 mg tsiku lililonse kwa masiku atatu, kenako 0,5 mg kawiri tsiku lililonse kwa masiku 4, kenako 1 mg kawiri tsiku lililonse pambuyo pake |
| Kodi mankhwalawa amatenga nthawi yayitali bwanji? | Masabata 7-12; zimasiyanasiyana | Masabata 12, atha kupitilira milungu ina 12 |
| Ndani amagwiritsa ntchito mankhwalawa? | Akuluakulu ndi achinyamata azaka 14 kapena kupitilira apo, ayenera kukhala opitilira 40.5 kg | Akuluakulu azaka 17 kapena kupitilira apo |
Zinthu zomwe Zyban ndi Chantix adachita
Zyban (bupropion) ndi Chantix (varenicline) onse akuwonetsedwa ngati chithandiziro pakusiya kusuta. Ngakhale mankhwalawa alibe chikonga.
Zyban ndi aminoketone antidepressant; njira yake yeniyeni yosuta fodya kapena kukhumudwa sikudziwika koma amaganiza kuti amaletsa kutenga norepinephrine ndi dopamine. Potero, kulakalaka chikonga kumachepa ndipo zizindikiritso zakuchepa zimachepa.
Osati kusokonezedwa ndi Wellbutrin, yomwe ilinso ndi bupropion, Zyban imagwiritsidwa ntchito pokhapokha pakusiya kusuta pomwe mtundu wa Wellbutrin wa bupropion umagwiritsidwa ntchito ku Major Depression Disorder ndi Seasonal Affective Disorder. Mankhwala awiriwa sasinthana. Komabe, madokotala ena amapereka Wellbutrin osalemba chifukwa chosiya kusuta.
Chantix imagwira ntchito poletsa ma nicotine receptors. Potero, dongosolo lamkati lamanjenje silimayambitsa dongosolo lolimbikitsira / mphotho lomwe limakhudzana ndi nikotini, ndipo mudzakhala wosasangalala m'maganizo ndi mthupi chifukwa chosuta. Chantix amachepetsanso zizindikiro zakusuta.
| Mkhalidwe | Zyban | Chantix |
| Kuleka kusuta | Inde | Inde |
Kodi Zyban kapena Chantix ndiwothandiza kwambiri?
Chitetezo ndi mphamvu ya Zyban adaphunziridwa angapo mayesero , pogwiritsa ntchito Zyban limodzi ndi uphungu. Pakafukufuku wamasabata asanu ndi awiri, Zyban adawonetsedwa kuti ndiwothandiza kwambiri kuposa placebo. Kwa miyezi isanu ndi umodzi, odwala adachita bwino kudziletsa atalandira chithandizo ndi Zyban. Pakafukufuku wina, chithandizo ndi Zyban chidalinso chothandiza kwambiri kuposa placebo, kuchepetsa chidwi chosuta, ndikuchepetsa zizindikiritso zakusiya (monga kukwiya, mkwiyo, ndi nkhawa).
Pazipatala mayesero wa Chantix, mankhwalawa adapezeka kuti amachepetsa chidwi chofuna kusuta, kuchepetsa zizolowezi zosuta, komanso kuthandiza odwala kudziletsa. Kafukufuku wina anayerekezera Chantix ndi Zyban ndi placebo. Kafukufukuyu anapeza kuti mankhwala onsewa anali abwino kuposa placebo, ndipo adazindikira kuti Chantix anali wothandiza kuposa Zyban.
Mankhwala othandiza kwambiri ayenera kutsimikiziridwa ndi dokotala wanu, poganizira zaumoyo wanu, mbiri yanu, ndi mankhwala ena omwe mukumwa omwe angagwirizane ndi Zyban kapena Chantix.
Kuyerekeza ndi kuyerekezera mtengo kwa Zyban vs. Chantix
Zyban generics nthawi zambiri amakhala ndi inshuwaransi komanso Medicare Part D. Popanda inshuwaransi, kupezeka kwa mwezi umodzi kwa generic Zyban kumawononga pafupifupi $ 90. Mutha kutsitsa mtengo uwu mpaka $ 50-80 ndi coupon ya SingleCare kutengera mankhwala apanyumba yanu.
Ndi Chantix, mudzayamba ndi muyezo wocheperako (paketi yoyambira mwezi), kenako pitirizani kudzaza paketi ya mwezi yopitilira mwezi wachiwiri ndi wachitatu. Chantix nthawi zambiri imakhala ndi inshuwaransi ndi Medicare Part D, yokhala ndi ma copay osiyanasiyana. Popanda inshuwaransi, paketi yoyambira mwezi imawononga pafupifupi $ 515 ndipo mwezi womwe ukupitilira umawononga $ 500. Mutha kuchepetsa mtengo wazogulitsa za Chantix ndi coupon ya SingleCare.
| Zyban | Chantix | |
| Nthawi zambiri amakhala ndi inshuwaransi? | Inde (generic) | Kawirikawiri; Zitha kufuna chilolezo cham'mbuyomu komanso / kapena kukhala ndi copay yayikulu |
| Nthawi zambiri amakhala ndi Medicare Part D? | Inde (generic) | Kawirikawiri; copays amasiyana kwambiri |
| Mlingo woyenera | 150 mg tsiku lililonse masiku atatu kenako 150 mg kawiri tsiku lililonse | 0.5 mg tsiku lililonse kwa masiku atatu, kenako 0,5 mg kawiri tsiku lililonse kwa masiku 4, kenako 1 mg kawiri tsiku lililonse (poyambira paketi imagwiritsidwa ntchito mwezi umodzi, kenako kupitiriza paketi kumagwiritsidwa ntchito) |
| Chitsanzo cha Medicare Part D copay | Avereji ya $ 3-64; zimasiyanasiyana | $ 25-578; zimasiyanasiyana |
| Mtengo wosakwatiwa | $ 58 | $ 400 poyambira paketi, $ 452 yopitilira paketi |
Zotsatira zoyipa za Zyban ndi Chantix
Kuphatikiza pa zovuta zoyipa / machenjezo, omwe afotokozedwa pansipa, mankhwala aliwonse amabwera ndi zovuta zoyipa. Zyban nthawi zambiri amapatsidwa limodzi ndi a chikonga cha chikonga (yemwenso amadziwika kuti nicotine replacement therapy, kapena NRT), ndipo zotsatira zoyipa zimatha kukhala zazikulu pamene Zyban imagwiritsidwa ntchito limodzi ndi chikonga.
Zotsatira zoyipa kwambiri za Zyban ndi kusowa tulo, mkamwa mouma, komanso chizungulire. Zotsatira zoyipa kwambiri za Chantix ndi nseru, kupweteka m'mimba, kupweteka mutu, ndi kugona tulo.
Chitsogozo cha mankhwala, chatsatanetsatane chokhudza mankhwalawa, adzakupatsani chiphaso chatsopano kapena chodzazitsanso cha Zyban kapena Chantix. Funsani wothandizira zaumoyo wanu kuti mupeze mndandanda wa zotsatirapo zake.
| Zotsatira zoyipa | Zyban: kuyenera? | Zyban: peresenti | Chantix: kuyenera? | Chantix: peresenti |
| Nseru | Inde | 9% | Inde | 30% |
| Kupweteka m'mimba | Inde | 3% | Inde | 7% |
| Kusowa tulo / vuto kugona | Inde | 40% | Inde | 18% |
| Maloto achilendo | Inde | 5% | Inde | 13% |
| Mutu | Ayi | - | Inde | khumi ndi zisanu% |
| Kutopa | Kawirikawiri | % sanapatsidwe | Inde | 7% |
| Chizungulire | Inde | 10% | Inde | Pafupipafupi:% sanaperekedwe |
| Pakamwa pouma | Inde | 10% | Inde | 6% |
Zotsatira: Tsiku ndi Tsiku (Chantix) ndipo Tsiku ndi Tsiku (Zyban)
Kuyanjana kwa mankhwala a Zyban vs. Chantix
Zyban ali ndi kuchuluka kwakanthawi kothandizirana ndi mankhwala, kotchulidwa mu tchati chili pansipa. Zambiri mwazogwiritsira ntchito mankhwalawa zimachitika chifukwa cha michere yotchedwa CYP2B6 ndi CYP2D6. Zitsanzo zina ndi mankhwala olanda komanso Digoxin, mankhwala amtima. Mowa uyenera kupewedwa mukakhala ku Zyban.
Kutengera ndi mawonekedwe a mankhwalawa, Chantix ilibe njira yothandizirana ndi mankhwala. Chantix sanaphunzire za chitetezo kuphatikiza ndi Zyban. Chantix ataphunzira limodzi ndi mankhwala osinthira chikonga, zovuta zoyipa monga nseru, kupweteka mutu, kusanza, chizungulire, kudzimbidwa, ndi kutopa, zinali zazikulu kwambiri kuposa ndi chikonga chokha.
Chantix sayenera kugwiritsidwa ntchito limodzi mowa , osachepera mpaka mutadziwa momwe Chantix imakhudzira kuthekera kwanu kulekerera mowa. Funsani omwe akukuthandizani kuti mumve zambiri.
| Mankhwala (s) | Gulu la mankhwala osokoneza bongo | Zyban | Chantix |
| Chikonga | Chithandizo chobwezeretsa chikonga | Ayi | Inde |
| Tegretol (carbamazepine), Neurontin (gabapentin), Lamictal (lamotrigine), Phenobarbital, Dilantin (phenytoin), Trileptal (oxcarbazepine), Topamax (topiramate), Depakote (divalproex sodium). | Mankhwala olanda, ena amagwiritsidwanso ntchito kuthana ndi kusinthasintha zochitika | Inde | Ayi |
| Klonopin (clonazepam), Valium (diazepam), Ativan (lorazepam) | Benzodiazepines | Inde | Ayi |
| Chidwi (clopidogrel) | Chotupa | Inde | Ayi |
| Mowa | Mowa | Inde | Inde |
| Lanoxin (digoxin) | Mtima glycoside | Inde | Ayi |
| Lopressor kapena Toprol XL (metoprolol), Tenormin (atenolol), Inderal (propranolol) | Beta-blockers | Inde | Ayi |
| Risperdal (risperidone), Haldol (haloperidol) | Mankhwala oletsa antipsychotic | Inde | Ayi |
| Effexor (venlafaxine), Pamelor (nortriptyline), Paxil (paroxetine), Prozac (fluoxetine), Zoloft (sertraline) | Mankhwala opatsirana | Inde | Ayi |
| Ultram (tramadol), Codeine | Opweteka | Inde | Ayi |
| Eldepryl (selegiline), Parnate (tranylcypromine) | Mao zoletsa | Inde | Ayi |
Mndandanda wamagulu azachipatala a Zyban ndiwotalika kwambiri kuti tilembere apa; funsani omwe akukuthandizani kuti mumve zambiri.
Machenjezo a Zyban ndi Chantix
Zyban machenjezo:
Zyban amabwera ndi chenjezo lakuda lakuda (chenjezo lamphamvu monga momwe a FDA amafunira, kuwonetsa chiwopsezo cha zochitika zazikulu kapena zowopsa) zodzipha. Zyban imakhala ndi bupropion, anti-depressant, ndi anti-depressants zitha kuwonjezera ngozi yakudzipha komanso kudzipha kwa odwala azaka 24 kapena kupitilira apo. Odwala ndi omwe amawasamalira akuyenera kudziwa kusintha kwamalingaliro, kuyerekezera zinthu m'maganizo, kuyerekezera zinthu, kusokeretsa, malingaliro ofuna kudzipha, nkhanza, nkhanza, kukwiya, nkhawa, ndi mantha. Wodwala aliyense wotenga Zyban, mosasamala kanthu za msinkhu, ayenera kuyang'aniridwa mosamala. Nazi machenjezo ena:
- Kuopsa kwa mania kapena psychosis; chiopsezo chikhoza kukhala chachikulu kwa odwala omwe ali ndi matenda osinthasintha zochitika.
- Zyban zingayambitse kugwidwa; chiopsezo chimakhudzana ndi mlingo. Mlingo sayenera kupitirira 300 mg patsiku. Matenda ena atha kukulitsa chiwopsezo cha kugwidwa.
- Zyban angayambitse kuthamanga kwa magazi; kuwunika kuthamanga kwa magazi mukamatenga Zyban.
- Odwala ena atha kukhala pachiwopsezo cha glaucoma; funsani dokotala wanu wa maso kuti mumve zambiri.
- Matenda akulu, omwe atha kuwononga khungu (matenda a Stevens-Johnson) atha kuchitika; Lumikizanani ndi omwe amakuthandizani azaumoyo mukangotuluka khungu.
Zyban iyenera kugwiritsidwa ntchito panthawi yapakati ngati phindu lomwe lingakhalepo likuthandizira chiopsezo kwa mwana wosabadwayo. Osuta oyembekezera ayenera kulimbikitsidwa kuti asiye kusuta pogwiritsa ntchito njira asanagwiritse ntchito Zyban. Zyban phukusi lowonjezera akuti chifukwa cha chiopsezo kwa mwana, amayi oyamwitsa ayenera kusiya kuyamwitsa kapena kuletsa Zyban. Funsani wothandizira zaumoyo wanu kuti akuthandizeni.
Machenjezo a Chantix:
Chantix amabwera ndi chenjezo la nkhonya pazochitika zazikulu za neuropsychiatric. Matenda okhumudwa, malingaliro ofuna kudzipha, kuyesa kudzipha, komanso kudzipha kwatchulidwa mwa odwala omwe amatenga Chantix. Muyenera kusiya Chantix ndikulumikizana ndi omwe amakuthandizani azaumoyo nthawi yomweyo mukayamba kusokonezeka, kudana, kukhumudwa, kapena kusintha machitidwe kapena malingaliro omwe siachilendo, kapena ngati mumakhala ndi malingaliro ofuna kudzipha. Nawa machenjezo ena okhudzana ndi Chantix:
- Kuopsa kwa hypersensitivity kapena angioedema, komwe ndikutupa kwa nkhope, pakamwa, (lilime, milomo, ndi m'kamwa), malekezero, ndi khosi. Imani Chantix ndikufunafuna chithandizo chadzidzidzi ngati izi zichitika.
- Monga Zyban, matenda a Stevens-Johnson amatha kuchitika. Lumikizanani ndi omwe amakuthandizani azaumoyo mukangotuluka khungu.
- Kuthekera kowonjezeka kwa zochitika zamtima; dziwitsani omwe amakuthandizani zaumoyo pazizindikiro zatsopano kapena zowonjezereka za matenda amtima.
- Samalani kuyendetsa kapena kugwiritsa ntchito makina mpaka mutadziwa momwe Chantix amakukhudzirani; kuvulala mwangozi kwachitika chifukwa chogona kapena chizungulire.
Amayi oyembekezera samalani ndi zotsatira za Chantix pa mwana wosabadwayo. Monga Zyban, omwe amasuta fodya ayenera kulimbikitsidwa kuti asiye kusuta pogwiritsa ntchito machitidwe. Chantix phukusi lowonjezera akuti chifukwa cha chiopsezo kwa mwana, amayi oyamwitsa ayenera kusiya kuyamwitsa kapena kusiya Chantix.
Odwala pa Chantix ayenera kuyang'aniridwa mosamala.
Mu 2016, the Adatero a FDA kuti chiwopsezo cha zovuta zoyipa zamaganizidwe kuchokera ku Zyban ndi Chantix chitha kukhala chocheperako kuposa momwe zimaganiziridwapo kale komanso kuti maubwino osuta fodya amapitilira chiwopsezo chogwiritsa ntchito mankhwalawa. Mosasamala kanthu, chidziwitso cha mankhwalawa chimakhalabe ndi machenjezo omwewo ndipo odwala ayenera kuyang'aniridwa kwambiri ali ku Zyban kapena Chantix.
Mafunso omwe amafunsidwa pafupipafupi za Zyban vs. Chantix
Zyban ndi chiyani?
Zyban (bupropion) ndi mankhwala omwe amagwiritsidwa ntchito ngati chithandizo pakusiya kusuta.
Chantix ndi chiyani?
Chantix (varenicline) ndi mankhwala omwe amagwiritsidwa ntchito ngati chithandizo pakusiya kusuta.
Kodi Zyban ndi Chantix ali ofanana?
Ayi. Mankhwala onsewa amagwira ntchito m'njira zosiyanasiyana kuti athandizire pakusiya kusuta. Njira yeniyeni ya Zyban sichidziwika koma imaganiziridwa kuti ndi yokhudzana ndi dopamine ndi norepinephrine. Chantix imagwira ntchito poletsa chikonga cholandirira, komanso kutsekereza kulimbikitsidwa ndi mphotho mkati mwa dongosolo lamanjenje. Ngakhale mankhwalawa alibe chikonga. Amakhalanso ndi mitengo yosiyana, kugwiritsa ntchito mankhwala osokoneza bongo, zotsatirapo zake, ndi machenjezo, monga tafotokozera pamwambapa.
Kodi Zyban kapena Chantix ndibwino?
Aliyense amachita mosiyanasiyana ndi mankhwala osiyanasiyana. Ndi dokotala wanu yekha yemwe angadziwe mankhwala omwe angakuthandizeni, poganizira mbiri yanu yazachipatala, matenda anu, ndi mankhwala ena omwe mukumwa.
Kodi pali njira ina kuposa Chantix?
Pakadali pano palibe njira ina yodziwika bwino kuposa Chantix.
Kodi Chantix Amathandiza Kusiya Kusuta?
Inde. Chantix itha kuthandizira kuchepetsa chidwi chanu chofuna kusuta ndikuthandizani ndi zizindikiritso zakusuta.
