FDA ivomereza Trijardy XR yamtundu wa 2 shuga

Nkhani

Nkhani yabwino kwa akulu omwe ali ndi matenda a shuga amtundu wa 2: Muli ndi njira yatsopano yothandizira kuchepetsa shuga m'magazi. US Food and Drug Administration (FDA) yalengeza kuvomereza kwa Trijardy XR. Piritsi yatsopano yophatikizira patatu imaphatikizira atatu mankhwala a shuga muzolemba kamodzi tsiku ndi tsiku:

• Glucophage ( metformin HCl ), chachikulu
• Chikhalidwe (linagliptin), cholepheretsa dipeptidyl peptidase-4 (DPP-4)
• Makhalidwe (empagliflozin), sodium-glucose co-transporter 2 (SGLT2) inhibitor

Piritsi ili silomwe limakhala mankhwala atsopano — ndikungolekanso mankhwala atatu omwe alipo, atero Dr. Marie Bellantoni, katswiri wodziwitsa anthu za endocrinologist ku The Center for Endocrinology ku Mercy Medical Center ku Baltimore, Maryland.

Komabe, chinthu chosavuta chingakhale chosangalatsa.

Kufikira pamene chilichonse chimawonjezera kutsata kwa wodwala mankhwala ndikwabwino-mapiritsi sagwira ntchito ngati salowa mwa wodwalayo-ndiye kuti izi ndizothandiza, akutero Dr. Anthu ena samangodandaula ngati akumwa mapiritsi ochepa.

Kodi Trijardy XR ndi chiyani?

Ena mwa mankhwala omwe ali mu Trijardy XR atha kumveka bwino kwa inu, ngati inu kapena wokondedwa wanu muli ndi matenda ashuga amtundu wa 2. Mwinanso munatenga chimodzi kapena zonsezi panthawi ina.

Metformin amalembedwa ngati chithandizo choyamba kwa anthu omwe ali ndi matenda amtundu wa 2. Zimathandiza kuchepetsa shuga m'magazi pochepetsa kuchepa kwa insulin m'thupi lanu. Amachepetsanso kuchuluka kwa shuga wopangidwa ndi chiwindi chanu komanso kuyamwa kwa thupi lanu shuga. Anthu ena amatenga metformin okha, koma ena amayenera kumwa mankhwala ena a shuga.

Chikhalidwe lakonzedwa kuti lithandizire anthu omwe ali ndi matenda a shuga amtundu wachiwiri kuti azitha kuyendetsa shuga, komanso kuchita masewera olimbitsa thupi komanso kudya. Zimathandiza kuchepetsa shuga m'magazi pochepetsa kuchuluka kwa shuga kotulutsidwa ndi chiwindi ndikuwonjezera kuchuluka kwa insulin komwe kumapangidwa ndi kapamba. Nthawi zambiri zimaperekedwa kwa anthu omwe amamwa kale mankhwala a shuga ndikusintha moyo wawo koma amafunikirabe thandizo kuti akwaniritse cholinga chawo cha A1C. (A1C imayeza kuchuluka kwa shuga m'magazi pamwezi wa miyezi itatu.) Imapezekanso piritsi limodzi tsiku lililonse.

Makhalidwe Ndi mankhwala ena omwe amatha kuthandiza anthu kutsitsa shuga m'magazi komanso kudya komanso kuchita masewera olimbitsa thupi, koma amathanso kuchepetsa ngozi yakufa kwamtima mwa anthu omwe ali ndi matenda a shuga achiwiri komanso matenda amtima. Ndi piritsi kamodzi patsiku lomwe limabwera m'mipangidwe iwiri (10 mg ndi 25 mg) ndipo imatha kutengedwa limodzi ndi mankhwala ena ambiri, kuphatikiza metformin, insulin, beta blockers, ACE inhibitors, ndi ma statins.

Mlingo wa Trijardy XR

Trijardy XR, yogulitsidwa ndi Boehringer Ingelheim Pharmaceuticals, Inc. ndi Eli Lilly ndi Company, ipezeka m'mayeso anayi:

• 5 mg empagliflozin, 2.5 mg linagliptin, 1000 mg metformin HCl yotulutsidwa
• 10 mg empagliflozin, 5 mg linagliptin, 1000 mg metformin HCl yotulutsidwa
• 12.5 mg empagliflozin, 2.5 mg linagliptin, 1000 mg metformin HCl yotulutsidwa
• 25 mg empagliflozin, 5 mg linagliptin, 1000 mg metformin HCl yotulutsidwa

Malinga ndi opanga, Trijardy XR ndiye piritsi loyamba kuphatikiza katatu kuphatikiza Jardiance. Jardiance idavomerezedwa koyamba ndi a FDA mu 2014, koma kuvomerezedwa kwake idakulitsidwa kumapeto kwa 2016 kuvomereza kugwiritsa ntchito kwake kuti muchepetse chiopsezo chakufa kwamtima.

Machenjezo a Trijardy XR

Trijardy XR sikuti imapangidwira anthu omwe ali ndi matenda amtundu wa 1 kapena anthu omwe ali ndi matenda ashuga ketoacidosis. Wopanga amachenjeza kuti Mankhwala sanaphunzire mwa anthu omwe ali ndi kapamba , choncho sizoyenera kwa anthu omwe ali ndi vutoli. Wopangayo amachenjezanso anthu omwe amakhala ndi zizindikilo za metformin yokhudzana ndi lactic acidosis kusiya kumwa mankhwala nthawi yomweyo. Sayeneranso kugwiritsidwa ntchito kwa iwo omwe ali ndi vuto lalikulu la impso, matenda a impso, kapena omwe ali ndi dialysis.

Vuto lina lomwe lingakhalepo chifukwa chophatikizira katatu ndikhoza kukhala kovuta kudziwa kuti ndi mankhwala ati omwe angakuchitikireni, atero Dr. Bellantoni.

Kugwiritsa ntchito moyenera mankhwala osakaniza atatu kungachitike pambuyo poti wodwalayo awonetsa kuyenera komanso kulekerera mankhwala omwe amaperekedwa padera, akutero, ndiye kuti amayamikiradi kuchepa kwa kuchuluka kwa mankhwala omwe amafunikiranso.

Komabe, ndi njira yodalirika yatsopano yothandizira. Tikukhulupirira Trijardy XR ili ndi mwayi wothandiza achikulire omwe ali ndi matenda a shuga amtundu wa 2 kusamalira bwino chithandizo chawo, makamaka iwo omwe amamwa mankhwala ena ndikugwira ntchito zosintha pamoyo wawo, Dr. Mohamed Eid, Wachiwiri kwa Purezidenti wa Clinical Development and Medical Affairs, Cardio- Metabolism and Respiratory Medicine for Boehringer Ingelheim Pharmaceuticals, Inc. adanena m'mawu olengeza kuvomerezedwa.