Waukulu >> Zambiri Zamankhwala >> Zotsatira zoyipa za propranolol ndi machitidwe, ndi momwe mungapewere

Zotsatira zoyipa za propranolol ndi machitidwe, ndi momwe mungapewere

Zambiri Zamankhwala

Propranolol (generic Inderal) ndi mankhwala omwe mumalandira omwe amachiza matenda a kuthamanga kwa magazi, monga kupweteka pachifuwa. Asanamwe mankhwalawa, odwala ayenera kudziwa zoyipa za propranolol, machenjezo, ndi machitidwe. Phunzirani momwe mungapewere zotsatirazi pansipa.

Kodi propranolol ndi chiyani?

Propranolol ndi mankhwala achiberekero omwe amagulitsidwanso ngati dzina Ndondomeko LA , Inderal XL, InnoPran XL, ndi Hemangeol. Ndi za beta-adrenergic blocking agents (kapena otchinga beta ) mankhwala osokoneza bongo, omwe amathandiza mtima kugunda mosavuta komanso mopanda mphamvu. Propranolol imapezeka pokhapokha polemba mankhwala. Nazi zina zathanzi lomwe Food and Drug Administration (FDA) yavomereza mankhwala kuchiza:

Mpweya: Kugunda kwamtima kosafulumira komwe kumachedwetsa kapena kuthamanga kwambiri.
Angina: Kupweteka pachifuwa komwe kumachitika pamene magazi samayenda bwino pamtima.
Kugwedezeka: Kuyenda modzipereka komanso mwaphokoso kwa miyendo, nkhope, zingwe zamawu, kapena mutu.
Matenda oopsa: Kuthamanga kwa magazi chifukwa cha mphamvu yamagazi motsutsana ndi makoma a mitsempha kukhala okwera kwambiri. Kuthamanga kwa magazi kumakhala pamwamba pa 140/90. Pulogalamu ya Propranolol-HCTZ , mankhwala omwe amaphatikiza propranolol ndi diuretic, amachiza matenda oopsa.
Matenda a mtima: Matenda a mtima (myocardial infarction) amachitika magazi akamatsekera pamtima. Propranolol imatha kuthandiza kupewa komanso kuchiza matenda amtima.
Migraine mutu: Migraines ndi mutu wopweteka kwambiri womwe propranolol imatha kuteteza. Ochita kafukufuku amaganiza kuti propranolol ndi yabwino kwa migraines chifukwa imatchinga hormone adrenaline poyambitsa nkhawa m'thupi.
Infantile hemangioma: Chotupa chokhala ndi chotupa chamagazi chomwe chingakhudze ana mpaka miyezi isanu.

Propranolol imatha kuthana ndi mavuto ena, monga nkhawa ndi mantha , pamlanduwu. Ochita kafukufuku akufufuza momwe propranolol imathandizira mitundu ina ya khansa . Mlingo wa propranolol umasiyana kutengera momwe zinthu ziliri ndipo umatha kuyambira 10 mg mpaka 160 mg.

ZOKHUDZA: Kodi Inderal LA ndi chiyani? | Kodi Propranolol ndi chiyani?

Zotsatira zoyipa za propranolol

Monga mankhwala aliwonse, nthawi zonse pamakhala zotheka. Nazi zotsatira zoyipa za propranolol:

Chizungulire
Mitu yopepuka
Kutopa
Kuchepetsa kugonana
Nseru
Kupweteka m'mimba
Kutsekula m'mimba
Kudzimbidwa

Zotsatira zoyipa za propranolol

Kutenga propranolol kumatha kubweretsa zovuta zoyipa. Nazi zina mwazovuta zoyipa zomwe zingachitike kwakanthawi kuti muzindikire mukamaganizira kapena kumwa propranolol:

Ziwerengero
Manja ozizira kapena mapazi ozizira
Minofu kufooka
Kupweteka kwa minofu
Kupuma pang'ono
Kutaya kukumbukira
Kusungidwa kwamadzimadzi
Shuga wamagazi amasintha
Kusowa tulo komanso zoopsa
Matupi awo sagwirizana
Kusanza
Kugwedezeka
Kulemera
Ziphuphu pakhungu

Anthu ena amada nkhawa kuti umunthu wawo usintha pakumwa propranolol, ndipo ngakhale ndizosowa, izi zitha kuchitika. Propranolol imatha kubweretsa kusintha kwamalingaliro ndi kukhumudwa. Ikhozanso kuyambitsa zovuta zokumbukira chifukwa cha momwe zimakhudzira norepinephrine ndi epinephrine, zomwe zimalumikizidwa ndi kukumbukira kukumbukira. Zosintha zilizonse ziyenera kuuzidwa mwachangu kwa dokotala.

Zotsatira zoyipa za propranolol zomwe zimafunikira kuchipatala mwachangu zimaphatikizapo kupuma movutikira, kupuma, kutupa kwa manja kapena nkhope, ndi kutupa khungu. Zizindikiro izi zimasonyeza kuti thupi lanu silimatha kuchita chilichonse, lomwe lingawononge moyo wanu.

Muyenera kusiya kumwa propranolol ngati zotsatira zoyipa zimachitika, koma motsogozedwa ndi dokotala, kutengera kuchuluka kwa mankhwala ndi zovuta zake, dokotala wanu angafune kuti muchepetse pang'onopang'ono propranolol, atero a Reuben Elovitz, MD, woyambitsa ndi Mtsogoleri wamkulu wa Zaumoyo Zachinsinsi ku Dallas . Pali zotsatira zomwe zingachitike mukamasiya mankhwala mwadzidzidzi kutengera chifukwa chomwe mudayambira.

Ngakhale kumwa mankhwala a propranolol kumatha kubweretsa zovuta, akadali mankhwala omwe amatha kuchita zabwino zambiri. Zimathandiza mtima kugwira ntchito, sizidzawononga mtima, ndipo zimakhala ndi zotsatira zabwino pachitetezo cha mthupi powonjezera kuchuluka kwa ma T amthupi. Nthawi zonse pamakhala zabwino ndi zoyipa pamankhwala aliwonse, ndipo kwa anthu ambiri, maubwino a propranolol amaposanso zovuta.

Kodi zotsatira za propranolol zimatenga nthawi yayitali bwanji?

Zotsatira zoyipa za propranolol zimatha kukhala masiku amodzi mpaka milungu. Zotsatira zoyipa zambiri zimatha masiku ochepa thupi likasintha. Kwa ena, kusintha kumeneku kumatha kutenga nthawi yayitali. Zotsatira zoyipa zimatha kukulira kapena kupitilira pomwe kuchuluka kwa mankhwala kumachepetsa kapena kuchepa. Zotsatira zoyipa za propranolol ndizotheka, koma izi sizichitika kwa aliyense.

Machenjezo a Propranolol

Propranolol si aliyense. Dr. Elovitz akufotokoza kuti anthu omwe ali ndi matendawa sayenera kumwa propranolol:

Bradycardia (kugunda kwamtima pang'onopang'ono)
Mphumu (kupuma movutikira kuchokera munjira zopumira)
Kulephera kwa mtima kosalamulirika (mtima osapopa bwino)
Matenda a m'mitsempha (otsekeka kapena kupopera mitsempha)
Matenda ashuga (matenda a shuga wambiri m'magazi)
Pheochromocytoma (chotupa cha adrenal gland minofu)
Myasthenia gravis (matenda ofooka a minofu)
Kuthamanga kwambiri (kuthamanga kwa magazi)
Orthostatic hypotension (kuthamanga kwa magazi komwe kumachitika mutayima pansi kapena kugona)

Anthu omwe amakhala ndi hyperthyroidism (chithokomiro chopitilira muyeso), matenda a Raynaud, matenda a chiwindi, matenda a impso, matenda am'mapapo, kapena matenda amtima, ayenera kukambirana ndi omwe amawapatsa chithandizo chamankhwala asanamwe mankhwala a propranolol. Kukhala ndi matendawa kumatha kuyambitsa vuto la propranolol, kumabweretsa mavuto ena azaumoyo.

Propranolol panthawi yoyembekezera

Propranolol ikhoza kukhala yotetezeka kwa amayi apakati kutenga. Sipanakhale maphunziro okwanira kuti atsimikizire momwe propranolol imakhudzira fetus, koma kafukufuku akuwonetsa kuti mankhwalawa amatha kuchokera kwa mayi kupita kwa khanda kudzera mkaka wa m'mawere. Amayi apakati kapena omwe angakhale ndi pakati ayenera kufunsa omwe amawapatsa chithandizo chamankhwala asanamwe kapena kusiya mwadzidzidzi propranolol.

Zoletsa zaka

Propranolol nthawi zina amagwiritsidwa ntchito pochiza matenda monga infantile hemangioma kwa ana ena, koma izi sizitanthauza kuti ndi mankhwala oyenera kwa mwana aliyense. Dokotala amangopatsa mwana mankhwala a propranolol ngati kuli kofunikira.

Propranolol imaperekedwa kwa okalamba mosamala, makamaka kwa omwe ali ndi chiwindi, impso, ndi mtima. Ena maphunziro akuwonetsa kuti achikulire oposa 60 omwe ali ndi matenda oopsa sayenera kumwa propranolol, koma odwala ena omwe ali ndi vuto la mtima angafune. Madokotala nthawi zonse amapereka mankhwala a propranolol pazochitika ndi zochitika.

Kugwiritsa ntchito nthawi yayitali ya propranolol

Monga beta-blocker, kugwiritsa ntchito kwa nthawi yayitali kwa propranolol kumatha kuteteza kupwetekedwa mtima komanso kukhalabe ndi kuthamanga kwa magazi. Si zachilendo kuti wina atenge beta-blockers kwa zaka zingapo, makamaka kutsatira matenda amtima, koma madotolo ayamba funso kaya kugwiritsa ntchito nthawi yayitali ndikofunikira.

Kugwiritsa ntchito beta-blockers kwakanthawi kochepa kumatha kuyambitsa zovuta zina ku kuipiraipira . Ikhozanso kuphimba zizindikiro za shuga wotsika m'magazi mwa anthu omwe ali ndi matenda ashuga, omwe atha kukhala owopsa. Mankhwala apamwamba a propranolol omwe amatengedwa nthawi yayitali amatha kupangitsa mavuto amtima kukulirakulira ndikupangitsa kugunda kwamtima mosasinthasintha.

Propranolol si mankhwala omwe munthu amatha kusiya nthawi yomweyo kumwa, ngakhale atakumana ndi zovuta zina. Kuletsa mwadzidzidzi propranolol kumatha kuyambitsa matenda amtima komanso kupweteka pachifuwa. Kufunsira kwa dokotala ndiyo njira yabwino kwambiri yosungira izi kuti zisachitike.

ZOKHUDZA: Momwe mungachepetse kuthamanga kwa magazi mwachangu komanso mwachilengedwe

Kuyanjana kwa Propranolol

Monga propranolol sichiyenera kutengedwa ndi aliyense, iyenso sayenera kumwa ndi mankhwala ena. Kutenga propranolol ndi mankhwalawa kumatha kuyambitsa mavuto:

Alpha blockers: Prazosin
Anticholinergics: Kutulutsa
Mankhwala ena othamanga magazi: Clonidine , acebutolol , nebivolol, Chinthaka , metoprolol
Mankhwala ena amtima: Quinidine , Chinthaka , alireza
Mankhwala a steroid: Prednisone
Mankhwala osagwiritsidwa ntchito poletsa kutupa (NSAIDs): Asipilini , ibuprofen
Mankhwala ena opatsirana pogonana: Fluoxetine , fluvoxamine

Mndandanda wa mankhwalawa suli wathunthu. Ogwira ntchito zaumoyo atha kupereka mndandanda wathunthu wamagwiritsidwe azamankhwala. Mavitamini ndi zowonjezera zowonjezera ndizabwino kumwa ndi propranolol, koma ena monga St. John's Wort mwina sangakhale.

Kupatula mankhwala, propranolol sayenera kutengedwa ndi mowa. Mowa umatha kuonjezera kuchuluka kwa magazi a propranolol, ndikupangitsa kuti asakhale otetezeka. Kumwa tiyi kapena khofi wambiri kuyeneranso kupewa chifukwa caffeine imatha kuwonjezera nkhawa komanso kuthamanga kwa magazi.

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Propranolol vs.propranolol ER zoyipa

Propranolol imabwera m'njira ziwiri zosiyanasiyana zomwe zimagwira ntchito mosiyana pang'ono. Kutulutsa propranolol pafupipafupi kuyenera kumwedwa kangapo patsiku kuti mutsimikizire kuti ndiwothandiza. Kutulutsa kwa Propranolol (ER) kumangofunika kumwedwa kamodzi patsiku chifukwa kumatulutsa pang'onopang'ono propranolol hydrochloride mthupi.

Pulogalamu ya ER amapezeka kuti mugule ngati 60 mg, 80 mg, 120 mg, ndi makapisozi a 160 mg. Pulogalamu ya muyezo wokhazikika ya propranolol ER ndi 80 mg yomwe imamwedwa kamodzi patsiku, yomwe ndiyokwera kuposa kuchuluka kwa propranolol yotulutsidwa mwachangu chifukwa imangotengedwa kamodzi.

Anthu ena amakonda kutulutsa kotulutsidwa chifukwa amangofunika kuda nkhawa zakumwa mankhwala awo kamodzi patsiku. Komabe, dokotala azitha kudziwa mtundu wabwino kwambiri kwa wina kutengera zosowa zake komanso zizindikiritso zake.

Actavis Elizabeth amapanga pulogalamu yotulutsa propranolol yowonjezera. Mankhwala a propranolol HCl ER ndi Hemangeol. Mankhwala a generic nthawi zambiri amakhala otchipa poyerekeza ndi maina amtundu wa dzina, koma amagwiranso ntchito mofananamo ndipo amathandizanso chimodzimodzi.

Zotsatira zoyipa zakatulutsidwa za propranolol ndi propranolol zowonjezera ndizofanana. Machenjezo omwewo, kusamala, komanso kuyanjana kwa mankhwala a propranolol amayimiranso propranolol ER.

Momwe mungapewere zotsatira zoyipa za propranolol

Njira yabwino yopewera zotsatirapo za propranolol ndikutsatira malangizo opanga ndi malangizo aliwonse omwe amaperekedwa ndi akatswiri azachipatala.

Mlingo wa Propranolol utengera zaka za wodwala, zizindikiritso zake, komanso mbiri yazachipatala, koma muyezo wokhazikika 40 mg amatengedwa kawiri patsiku. Mapiritsi otulutsa pulogalamu ya propranolol nthawi zonse amayenera kumwedwa m'mimba yopanda kanthu kuti muonetsetse kuti thupi lanu likulowa bwino. Mapiritsi otulutsa Propranolol otulutsidwa (ER) atha kumwa kapena opanda chakudya, koma amayenera kumwedwa nthawi zonse, kaya ndi chakudya, kuti atsimikizire kuti thupi limayamwa mayeza ofanana. Komanso, kutenga propranolol ER ndi chakudya kumatha kuthandiza kupewa kupwetekedwa m'mimba ndikukumbukira KUTI musatafune kapena kuphwanya mapiritsi a ER kapena mulingo wonsewo ungatengeke mwachangu kwambiri. Propranolol amatengedwa kamodzi m'mawa komanso nthawi yogona asanagone, koma izi zimatha kusintha kutengera malingaliro a wothandizira zaumoyo.

Mankhwala osowa a propranolol amathanso kuyambitsa mavuto. Kutenga mankhwala omwe mwaphonya mukangokumbukira kungakuthandizeni kupewa zovuta zomwe zingachitike kapena kukulirakulira. Komabe, ngati ili pafupi nthawi yoti mutenge mlingo wotsatira, ndiye kuti wodwalayo sayenera kumwa mlingo wowonjezera kuti apange ndalama zomwe zasowa.

Propranolol iyenera kusungidwa kutentha kutentha, kutentha kwa dzuwa, komanso kuzizira kwambiri. Zinthu zachilengedwezi zitha kusintha mankhwala ndi momwe zimagwirira ntchito. Sungani mankhwala osokoneza bongo patali ndi ana. Funsani uphungu mwachangu ngati mwana watenga propranolol mwangozi.

Ngati zovuta za propranolol ndizowopsa, madokotala amatha kukupatsani mankhwala ena. Chifukwa chakuti wina ayamba kumwa beta-blocker ngati propranolol, sizitanthauza kuti ayenera kuyitenga kosatha. Mankhwala monga Zoletsa za ACE ndipo ma ARB amathandizanso mikhalidwe yofanana ndi yomwe beta-blockers amachita, ndipo atha kugwira bwino ntchito kwa anthu ena. Nawa ena mwa omwe amalembedwa kwambiri a ACE inhibitors ndi ma ARB: