Waukulu >> Zambiri Zamankhwala >> Levaquin ndi chiyani ndipo imagwiritsidwa ntchito bwanji?

Levaquin ndi chiyani ndipo imagwiritsidwa ntchito bwanji?

Levaquin ndi chiyani ndipo imagwiritsidwa ntchito bwanji?Zambiri Zamankhwala

Levaquin anasiya mu December 2017. Lankhulani ndi dokotala wanu za njira zina kuphatikizapo generic levofloxacin kapena fluoroquinolones ena.





Kodi matenda a sinus, chibayo, matenda a impso, ndi anthrax amafanana bwanji? Matendawa akamayambitsidwa ndi bakiteriya, amatha kulandira mankhwala opha tizilombo otchedwaLevaquin. Mabakiteriya amabwera mosiyanasiyana. Amalumikizana ndi thupi m'njira zosiyanasiyana, ndikupangitsa chilichonse kuyambira matenda ang'onoang'ono mpaka matenda akulu. Ndicho chifukwa chake maantibayotiki osiyanasiyana monga Levaquin ndi amoxicillin amafotokozedwa kwambiri. Amatha kulimbana ndi mabakiteriya pafupifupi gawo lirilonse la thupi, kuwapanga kukhala owonjezera oyenera kubokosi lazida lililonse la wothandizira zaumoyo.



Koma Levaquin sichochiritsira chozizwitsa-ndi mankhwala ovuta omwe amakhala ndi kulumikizana mosavomerezeka komanso zovuta zina zomwe zingakhale zovuta. Pali zambiri pansi pano. Gwiritsani ntchito nkhaniyi ngati choyambira pa Levaquin, chitsogozo chamankhwala chofunikira kwambiri chokhudza ntchito zake, momwe amagwirira ntchito, ndi zotsatira zake.

Levaquin ndi chiyani?

Levaquin ndi mankhwala omwe amachiza matenda osiyanasiyana am'mapapo m'mapapo, kwamikodzo, impso, sinus, ndi khungu. Opereka chithandizo chamankhwala nthawi zambiri amapatsidwa mankhwala ochizira chibayo, bakiteriya sinusitis, bronchitis, prostatitis, ndi matenda am'mikodzo.

Ndi maantibayotiki osiyanasiyana omwe amabwera m'njira zosiyanasiyana. Opereka chithandizo chamankhwala atha kugwiritsa ntchito mankhwala am'kamwa, amitsempha, komanso ophthalmic kuti athetse matenda am'mabakiteriya amitundu yosiyanasiyana, malinga ndi Justin Friedlander, MD, urologist wa Einstein Healthcare Network .



Chogwiritsira ntchito ndi mankhwala otchedwa levofloxacin, mtundu wa mankhwala a fluoroquinolone antibiotic. Levaquin ndi dzina lodziwika lomwe linapangidwa ndi kampani yothandizira ya Johnson & Johnson ya Janssen Pharmaceuticals. Fluoroquinolones imagwiritsa ntchito ma enzyme awiri osiyana omwe ndi ofunikira kuti mabakiteriya abwererenso, kuti maselo asachulukane. Koma imagwira ntchito mabakiteriya okha, osati mavairasi, chifukwa chake Levaquin siyothandiza pachimfine, chimfine, kapena matenda ena a virus (monga coronavirus, kapena COVID-19).

Ngakhale ndi maantibayotiki othandiza kwambiri, Levaquin amayambitsa zovuta zina zowopsa, chifukwa chake sichipezeka pakauntala. Amapezeka pokhapokha pamankhwala kuti wothandizira zaumoyo athe kuwunika momwe zinthu zilili kuti agwiritsidwe ntchito.

Kodi Levaquin amagwiritsidwa ntchito bwanji?

Pali gulu lonse la mabakiteriya osiyanasiyana kunjaku, ndipo Levaquin imagwira ntchito polimbana ndi ambiri mwa iwo, kuphatikiza E. coli, Staphylococcus, ndi Streptococcus. M'malo mwake, levofloxacin ndi abale ake apamtima amatchedwa fluoroquinolones opumira chifukwa chothandiza motsutsana ndi Streptococcus pneumoniae makamaka.



Nthawi zambiri, levofloxacin imachita:

  • Matenda bronchitis
  • Chibayo cha bakiteriya
  • Matenda ovuta komanso osavuta
  • Matenda a impso (monga pyelonephritis)
  • Matenda a prostate
  • Matenda a khungu
  • Matenda a Sinus

Nthawi zina, othandizira azaumoyo adzaperekanso levofloxacin yokhudzana ndi matenda amkati mwa m'mimba, anthrax pambuyo poonekera, mitundu ina ya mliri, ndi matenda otsekula m'mimba opatsirana ndi matenda a E. coli. Kuphatikiza apo, zawonetsa zina zothandiza pochiza matenda ena opatsirana pogonana, makamaka chlamydia .

Pezani khadi yochotsera ya SingleCare



Komabe, chiwopsezo chazovuta zoyipa za Levaquin sichabwino pazifukwa zazing'ono. M'malo mwake, Food and Drug Administration (FDA) yanena , fluoroquinolones iyenera kusungidwa kuti igwiritsidwe ntchito kwa odwala… omwe alibe njira zina zochiritsira.

Mukufuna mtengo wabwino pa Levaquin?

Lowani zidziwitso zamitengo ya Levaquin kuti mupeze kuti mitengo ikasintha liti!



Pezani zidziwitso zamitengo

Mlingo wa levaquin

Mlingo wa Levaquin tsiku lililonse umapezeka m'mapiritsi amlomo a 250, 500, kapena 750 mg. Tengani Levaquin ndi madzi okwanira. Mlingowo umatha kusiyanasiyana kutengera mtundu wa momwe zinthu ziliri, njira yoyendetsera, msinkhu wa wodwala, kulemera kwa wodwalayo, ndi mankhwala ena.



Monga maantibayotiki olimba, levofloxacin iyamba kugwira ntchito patangopita maola ochepa, koma atha kukhala masiku awiri kapena atatu zizindikilo zisanayambike. Tengani mitundu yonse ya maantibayotiki malinga ndi zomwe wothandizira zaumoyo wanena, ngakhale mutakhala bwino pakatha masiku ochepa.

M'munsimu muli mankhwala akulimbikitsidwa ndi FDA akuluakulu omwe ali ndi vuto la impso.



Matendawa Mlingo woyenera
Chibayo cha nosocomial 750 mg tsiku lililonse kwa masiku 7-14
Chibayo chopezeka mderalo 500 mg tsiku lililonse kwa masiku 7-14 kapena 750 mg tsiku lililonse kwa masiku 5 (kutengera mabakiteriya)
Kuwonjezeka kwa bakiteriya kwa bronchitis yanthawi yayitali 500 mg tsiku lililonse kwa masiku 7
Bakiteriya wamkulu sinusitis (matenda a sinus) 750 mg tsiku lililonse masiku 5 kapena 500 mg tsiku lililonse kwa masiku 10-14
Matenda a bacterial prostatitis (matenda a prostate) 500 mg tsiku lililonse kwa masiku 28
UTI yovuta 750 mg tsiku lililonse kwa masiku 5 kapena 250 mg tsiku lililonse kwa masiku 10 (kutengera mabakiteriya)
Matenda a anthrax 500 mg tsiku lililonse kwa masiku 60
Mliri 500 mg tsiku lililonse kwa masiku 10-14

Machenjezo

Amayi omwe ali ndi pakati kapena akuyamwitsa ayenera kufunsa omwe amawapatsa chithandizo chamankhwala asanatenge Levaquin. Sipanakhalepo maphunziro okwanira kapena oyendetsedwa bwino mwa amayi apakati. Levofloxacin imadutsa mkaka wa m'mawere, choncho kuyamwitsa sikuvomerezeka pa chithandizo cha Levaquin. Amayi oyamwa angaganize kupopera ndi kutaya mkaka wa m'mawere akamamwa mankhwala ndi Levaquin komanso masiku ena awiri (ofanana ndi theka la miyoyo) pambuyo pa mlingo womaliza.

Levofloxacin imapezeka kwa okalamba (65 kapena kupitilira apo), koma imatha kukhalabe m'dongosolo lawo nthawi yayitali chifukwa cha kuchepa kwa impso. Pazochitikazi, opereka chithandizo chamankhwala nthawi zambiri amachepetsa mlingo kuti akwaniritse. Maantibayotiki sanalandiridwe ndi FDA kwa ana ochepera zaka 18 kupatula ngati atadwala anthrax kapena mliri chifukwa cha zovuta zake kuthekera kopanga mabakiteriya osagwira mankhwala .

Kuyanjana kwa Levaquin

Ngakhale kuti nthawi zina amagwiritsidwa ntchito pophatikiza limodzi, Levaquin sayenera kumwedwa limodzi ndi mankhwala ena, chifukwa zimatha kuyambitsa zovuta zamagulu. Musatenge Levaquin nthawi imodzi ndi:

  • Maanthibayidi, Carafate ( wotsatira ), zitsulo zamkuwa (monga chitsulo), ndi ma multivitamini : Izi zimatha kuletsa kuyamwa kwa levofloxacin m'matumbo. Zakudya za mkaka ndi zakudya zina zokhala ndi calcium zambiri zimatha kukhala ndi zotsatirapo zofananira.
  • Kutulutsa ( alireza ): Mankhwalawa a HIV amathanso kupewa kuyamwa kwa levofloxacin m'mimba.
  • Coumadin ( warfarin ): Levaquin ikhoza kukweza zotsatira za warfarin, ndikuwonjezera ngozi yakutaya magazi.
  • Maantibayotiki: Pamodzi ndi Levaquin, izi zimayambitsa kusinthasintha kwa milingo ya shuga wamagazi.
  • Mankhwala osagwiritsidwa ntchito poletsa kutupa (NSAIDs): Kupweteka kumachepetsa ngati ibuprofen kapena aspirin kumatha kuwonjezera chiopsezo cha kukondoweza kwamitsempha yapakati komanso kukomoka.
  • Theophylline : Poona zamankhwala, mankhwalawa adalumikizana ndi ma fluoroquinolones ena kuti awonjezere chiwopsezo cha zovuta zapakati, kuphatikizapo kugwidwa.

Izi ndizomwe zimachitika kwambiri, koma mndandandawu suzungulira. Odwala ayenera kudziwitsa omwe akupereka chithandizo chamankhwala za mankhwala ena aliwonse omwe amamwa.

Zotsatira zoyipa za Levaquin ndi ziti?

Janssen wakhala akumenyedwa milandu ndikuwunikidwa mozama pazotsatira za Levaquin. Ndipo ngakhale zili bwino kukumbukira mavuto ena, odwala omwe amatsatira mosamalitsa upangiri wa zamankhwala ndikufotokozera zovuta zawo nthawi yomweyo sayenera kutaya tulo pa iwo. Zotsatira zoyipa kwambiri za Levofloxacin zimakhudza makamaka ziwalo zam'mimba ndi zamitsempha, atero Dr. Friedlander, chifukwa chake aliyense amene amamwa ayenera kusamala:

  • Nseru kapena kusanza
  • Kutsekula m'mimba
  • Kudzimbidwa
  • Kupweteka mutu
  • Chizungulire
  • Kutaya njala
  • Kuvuta kugona

Osati zoyipa, sichoncho? Zonsezi ndizotsatira zoyipa zomwe zimakonda kupezeka pamakalata amankhwala osiyanasiyana. Koma, mwatsoka, amenewo sindiwo mathero. M'zaka zingapo zapitazi, Levaquin wakhala pansi pa microscope ya media pazambiri zake, zambirizotsatira zoyipa.

Zotsatira zoyipa komanso zovuta

Kugwiritsa ntchito Levaquin kumalumikizidwa ndi tendinitis (kutupa kwa tendon) komanso kuphwanya, kung'amba, ndi kuphulika, makamaka mu tendon ya Achilles, kumbuyo kwa bondo. Odwala omwe ali ndi mbiri ya tendinitis, kuvulala, kapena mavuto ena a tendon ayenera kukhala osamala kwambiri pakutenga Levaquin.

Palinso mwayi woti Levaquin imatha kuyambitsa kuwonongeka kwa mitsempha (zotumphukira za m'mitsempha) m'manja, miyendo, manja, ndi mapazi, zomwe zimawonetsa kupweteka, kufooka, kuwotcha, kulira, kapena kufooka. Zomwe zimachitika pakatikati pa mitsempha monga kukomoka, mutu wopepuka, kunjenjemera, chisokonezo, kuyerekezera zinthu m'maganizo, komanso mavuto ena azaumoyo nawonso ndiwotheka.

Levaquin imatha kuyambitsa mavuto amtima monga kuchuluka kwa kugunda kwa mtima, kugunda kwamtima kosazolowereka, ndi kupindika kwa minyewa kapena misozi. Zotsatirazi zimatha kubweretsa chifuwa mwadzidzidzi, m'mimba, komanso kupweteka msana. Kuphatikiza apo, shuga wotsika kapena wokwera kwambiri ndizotheka, chifukwa chake anthu omwe ali ndi matenda ashuga ayenera kusamala kwambiri.

Anthu ena omwe amatenga Levaquin amathanso kukhala ndi chidwi chakuwala kwa dzuwa, zomwe zimawotcha kwambiri dzuwa, zotupa, komanso zotupa pakhungu atangokhala chete osapaka sunscreen. Mukamatenga Levaquin, pewani dzuwa (ndi mabedi ofufuta) ngati zingatheke. Ngati muli padzuwa kwakanthawi kochepa, valani zoteteza ku dzuwa ndi chipewa ndi zovala zokutira pakhungu.

Ena atha kukhala ndi vuto la chiwindi lodziwika ndi khungu lachikaso kapena azungu amaso, mkodzo wakuda, kusanza, kupweteka m'mimba, ndi mipando yonyezimira.

Ndipo aliyense amene ali ndi vuto losawerengeka myasthenia gravis atha kuwona kuti vuto lawo likuipiraipira ndi chithandizo cha Levaquin. Zina mwazizindikirozi zimaphatikizapo kufooka kwa minofu, zikope zothothoka, zovuta kumeza, komanso kusawona bwino.

Pamwamba pa zonsezi, Levaquin imatha kuyambitsa vuto linalake lomwe limakhala ndi zidzolo, ming'oma, kutupa, kuyabwa, ndipo - poyipa kwambiri - anaphylaxis.

Zotsatira zoyipa, zomwe zingakhale zofala kapena zowopsa, zimatha kuchitika patatha milungu ingapo kuchokera pomwe zitha kuwonetsedwa ndipo zitha kukhala zachikhalire, atero Dr. Friedlander, akunena za 2016 FDA chenjezo.

Ndilo mndandanda wolimba kwambiri wazomwe zitha kukhala ndi zovuta, ndipo zitha kuwoneka zowopsa, koma kumbukirani kuti izi sizachilendo. Ndi zabwino kungowakumbukira, makamaka kwa aliyense amene ali ndi mikhalidwe yomwe ingakhalepo yomwe ingagwirizane ndi mankhwala a Levaquin.

Kodi pali njira zina m'malo mwa Levaquin?

Levaquin si mankhwala okhawo a fluoroquinolone kunja uko. M'malo mwake, pali mankhwala ena ochepa omwe angalandire mawonekedwe ofanana. Chifukwa chake, othandizira azaumoyo ali ndi njira zingapo zochiritsira komanso njira zothanirana ndi mabakiteriya omwe amapezeka. Njira zochepa zomwe Levaquin amagwiritsa ntchito ndi monga:

  • Kupro ( ciprofloxacin ): Ichi ndi chimodzi mwa mankhwala ofanana kwambiri a Levaquin. Ndi mankhwala osiyanasiyana, koma popeza onsewa ndi fluoroquinolones, amathandizira mikhalidwe yofananira ndipo amakhala ndi zovuta zofananira (zodziwika komanso zowopsa). Othandizira azaumoyo amathanso kugwiritsa ntchito Cipro kuchiza matenda a typhoid fever ndi mitundu ina ya chinzonono.
  • Avelox ( moyankwo ): Avelox ndi fluoroquinolone ina yomwe ikufanana ndendende ndi Levaquin. Mankhwala onsewa amatha kuchiza matenda osiyanasiyana a bakiteriya. Ngakhale zili choncho, odwala omwe akutenga Avelox amakhala pachiwopsezo cha zovuta zoyipa zomwezo. Avelox imapezeka mu mawonekedwe achibadwa, monga moxifloxacin.
  • Bactrim (sulfamethoxazole / trimethoprim): Bactrim ndi mankhwala omwe amagwiritsidwa ntchito pochiza matenda am'makutu, UTIs, kutsegula m'mimba, kuyenda kwa bronchitis, ndi mitundu ina ya chibayo. Komabe, ndi ochokera ku gulu lina la mankhwala osokoneza bongo kuposa Levaquin ndipo samakhala pachiwopsezo chofanana cha zovuta zoyipa monga kuphulika kwa tendon kapena aortic aneurysm. Odwala omwe ali ndi vuto la sulfa sayenera kumwa Bactrim.
  • Zithromax ( azithromycin ): Awa ndi maantibayotiki ena ochokera ku gulu lina la mankhwala, lotchedwa macrolide antibiotics. Zithromax (Z-Pak) amachiza matenda am'mero, matenda am'makutu, bakiteriya conjunctivitis, bakiteriya sinusitis, ndi matenda ena a bakiteriya. Koma monga Bactrim, zovuta zake sizocheperako kuposa Levaquin.
  • Keflex ( cephalexin ): Keflex ndi ofanana kwambiri ndi penicillin kuposa Levaquin, koma amapatsidwa matenda ena omwewo, monga bronchitis, chibayo, ndi UTIs. Keflex amathanso kuchiza zilonda zapakhosi ndi laryngitis.
  • Levofloxacin yachibadwa : Awa ndi mankhwala omwewo monga Levaquin, popanda dzina lenileni. Levaquin satha kupanga, koma generic levofloxacin imapezekabe kudzera mwa mankhwala.

Kodi Levaquin watha?

Inde. Mu Disembala 2017, Janssen Pharmaceuticals adakoka Levaquin ndi fluoroquinolone ina yotchedwa Floxin Otic khutu kuchokera pakupanga. Janssen adati izi zidaganiza zosiya Levaquin pakupezeka kwa njira zina, komabe, panali milandu ingapo pazovuta zoyipa. Milanduyi idachokera kwa odwala a Levaquin omwe adakumana ndi zovuta zina zomwe zafotokozedwa pamwambapa atamwa mankhwalawa, makamaka kuphulika kwa aortic ndi kuphulika kwa tendon. Amati makampaniwa adagulitsa mankhwalawa ngakhale anali ndi zovuta zowopsa.

Asanachitike milandu iyi, a FDA anali atapereka fomu ya chenjezo lakuda kwa Levaquin, limodzi ndi Cipro, Avalox, ndi ma fluoroquinolones ena, chenjezo lomwe lidaperekedwa pazovuta zoyipa kwambiri. Ndilo chenjezo lamphamvu lomwe a FDA apereka asanaletse mankhwala. Ochita nawo mpikisano monga Cipro, Avalox, ndi ma fluoroquinolones ena akadali pamsika, ndipo levofloxacin generic imapezekabe.

Panthawi yosiya kwake mu 2017, panali Levaquin yokwanira yomwe idapangidwa kale ndikutumizidwa kuti ipitirire 2020. Chifukwa chake, miyezi ingapo ikubwerayi mwina idzakhala yomaliza yomwe tidzawona dzina la Levaquin, ngakhale lipitilizabe kupikisana nawo pafupi ndi mnzake wa generic.