Waukulu >> Mankhwala Osokoneza Bongo Vs. Mnzanu >> Cymbalta vs. Lexapro: Kusiyana, kufanana, ndi zomwe zili zabwino kwa inu

Cymbalta vs. Lexapro: Kusiyana, kufanana, ndi zomwe zili zabwino kwa inu

Mankhwala osokoneza bongo Vs. Mnzanu

Cymbalta ndi Lexapro ndi mankhwala awiri omwe amagwiritsidwa ntchito kwambiri pochiza matenda onse okhumudwa (MDD) ndi matenda amisala (GAD). Matenda akulu okhumudwitsa ndi akuti zingakhudze pafupifupi akulu 16 miliyoni ku United States. Amadziwika ndi nkhawa kwakanthawi kosachepera milungu iwiri. Odwala amathanso kuwonetsa kusowa chidwi ndi zinthu zomwe amakonda kapena mphamvu zochepa. Odwala ena amamva ululu popanda chifukwa chodziwika.

Matenda a nkhawa wamba ndi akuti zingakhudze Akuluakulu 6.8 miliyoni ku United States. Amadziwika ndi kuda nkhawa kwambiri pazinthu zosiyanasiyana kuphatikizapo ndalama, banja, thanzi, ndi ntchito. Amapezeka kuti odwala akakhala ndi nkhawa masiku ambiri kuposa miyezi isanu ndi umodzi.

Ngakhale Cymbalta ndi Lexapro onse amagwiritsidwa ntchito pochiza matendawa ndi ena ambiri, pali kusiyana kwakukulu pakati pa mankhwala awiriwa.

Kodi pali kusiyana kotani pakati pa Cymbalta ndi Lexapro?

Cymbalta (duloxetine) ndi mankhwala akuchipatala omwe amawonetsedwa pochiza MDD ndi GAD. Cymbalta ndi gulu la antidepressants omwe amatchedwa serotonin-norepinephrine reuptake inhibitors (SNRIs). Mu synapse ya neuron, Cymbalta imatseka kubwezeretsanso kwa norepinephrine ndi serotonin. Izi zimapangitsa kuti ma neurotransmitters azitha kupezeka kuti azitha kuchita zinthu mosangalatsa komanso kukhudza. Ma SNRI ena omwe mungawadziwe ndi Effexor (venlafaxine) ndi Pristiq (desvenlafaxine).

Cymbalta imapezeka ngati 20 mg, 30 mg, ndi 60 mg kapisozi wamlomo.

Lexapro (escitalopram) ndi mankhwala omwe amathandizidwa ndi MDD ndi GAD. Lexapro ndi gulu la mankhwala opatsirana pogonana omwe amadziwika kuti serotonin reuptake inhibitors (SSRIs). Lexapro imagwira ntchito poletsa kubwezeretsanso kwa serotonin papampu yotumiza ma neuronal. Izi zimasiya serotonin yaulere mu synapse ya neuron. Ma SSRI ena omwe mungawadziwe ndi Prozac, Zoloft, Celexa, kapena Paxil.

Lexapro imapezeka ngati piritsi pakamwa mu mphamvu ya 5 mg, 10 mg, ndi 20 mg. Ikupezekanso ngati yankho la pakamwa mu ndende ya 5 mg / 5 ml.

Kusiyana kwakukulu pakati pa Cymbalta ndi Lexapro
	Cymbalta	Kameme
Gulu la mankhwala osokoneza bongo	Kusankha serotonin-norepinephrine reuptake inhibitor	Kusankha serotonin reuptake inhibitor
Chizindikiro cha Brand / generic	Zolemba ndi generic zilipo	Zolemba ndi generic zilipo
Kodi dzina lachibadwa ndi liti?	Duloxetine	Kuyanjana
Kodi mankhwalawa amabwera mwa mawonekedwe ati?	Makapisozi apakamwa	Piritsi lapakamwa ndi yankho la m'kamwa
Kodi mulingo woyenera ndi uti?	60 mg kamodzi patsiku	10 mg kamodzi patsiku
Kodi mankhwalawa amatenga nthawi yayitali bwanji?	Kutalika (miyezi mpaka zaka)	Kutalika (miyezi mpaka zaka)
Ndani amagwiritsa ntchito mankhwalawa?	Achinyamata ndi achikulire	Achinyamata ndi achikulire

Zomwe zimachitidwa ndi Cymbalta ndi Lexapro

Monga tanenera kale, Cymbalta ndi Lexapro onse akuwonetsedwa kuti athetse vuto lalikulu lachisokonezo komanso matenda a nkhawa. Cymbalta imavomerezedwa pazizindikiro zina zapadera zokhudzana ndi matenda amitsempha ndi minofu ndi mafupa. Izi zikuwonetsa kuti Cymbalta imasiyana ndi mankhwala ena opatsirana pogonana chifukwa ndi okhawo omwe amavomerezedwa ndi matenda opatsirana. Nthawi zina Lexapro imagwiritsidwa ntchito ngati chizindikiro chazovuta zakuya, bulimia nervosa, ndi kudya kwambiri.

Tchati chotsatirachi chimapereka mndandanda wazomwe zathandizidwa ndi Cymbalta ndi Lexapro. Sizingakhale ndi zonse zomwe zingagwiritsidwe ntchito, ndipo nthawi zonse muyenera kufunsa akatswiri azachipatala kuti muwone ngati imodzi mwa mankhwalawa ndi yoyenera kwa inu.

Mkhalidwe	Cymbalta	Kameme
Kusokonezeka kwakukulu	Inde	Inde
Matenda amisala wamba	Inde	Inde
Fibromyalgia	Inde	Ayi
Zowawa zaminyewa zaminyewa	Inde	Ayi
Kupweteka kwa m'mitsempha yokhudzana ndi matenda a shuga	Inde	Ayi
Chemotherapy-yomwe imayambitsa zotumphukira za m'mitsempha	Kutumiza	Ayi
Kupsinjika kwamikodzo kusagwirizana (amuna)	Kutumiza	Ayi
Kuledzera	Ayi	Kutumiza
Bulimia mantha	Ayi	Kutumiza
Matenda osokoneza bongo	Ayi	Kutumiza
Kusokonezeka kwamantha	Ayi	Kutumiza
Matenda a Posttraumatic	Ayi	Kutumiza
Matenda a premenstrual dysphoric	Ayi	Kutumiza
Kuthamangira msanga	Ayi	Kutumiza

Kodi Cymbalta kapena Lexapro ndi yothandiza kwambiri?

KU kusanthula meta adawunikiranso kafukufuku poyerekeza duloxetine ndi escitalopram ndi ma SSRIs ena wamba. Kafukufukuyu adawona kuti pankhani yothana ndi kukhumudwa kwakukulu, duloxetine imalephera kuwonetsa phindu panjira yothandizidwa ndi SSRIs. Komabe, malinga ndi kuwunikaku, odwala atha kusiya duloxetine chifukwa cha zovuta. Mphindikati kusanthula meta adanenanso izi. Sizingatheke kunena ngati Cymbalta kapena Lexapro ali bwino kuposa enawo pothetsa kukhumudwa. Kuwonjezeka kwa zovuta zoyipa ndi Cymbalta kungakhale chinthu chofunikira kuganizira posankha mankhwala.

Kuphunzira ndi kuyerekezera mtengo wa Cymbalta vs. Lexapro

Cymbalta ndi mankhwala akuchipatala omwe nthawi zambiri amapangidwa ndi mapulani azamalonda ndi a Medicare. Mtengo wamthumba wa Cymbalta 60 mg utha kukhala wopitilira $ 300, koma ndi coupon yochokera ku SingleCare, mutha kupeza generic yotsika $ 15 kuma pharmacies omwe akutenga nawo mbali.

Lexapro ndi mankhwala omwe amalembedwa ndi malonda ndi mankhwala a Medicare. Mtengo wakuthumba kwamasiku 30 wa Lexapro 10 mg utha kukhala $ 400. SingleCare imapereka coupon ya generic Lexapro, yomwe imatha kutsitsa mtengo mpaka $ 10 kapena kuchepera.

Khadi lochotsera mankhwala

	Cymbalta	Kameme
Nthawi zambiri amakhala ndi inshuwaransi?	Inde	Inde
Nthawi zambiri amadzazidwa ndi Medicare?	Inde	Inde
Mlingo woyenera	30, 60 mg makapisozi	30, 10 mg mapiritsi
Wopanga Medicare wamba	Osakwana $ 10	Osakwana $ 10
Mtengo wosakwatiwa	$ 15 +	$ 10 +

Zotsatira zoyipa za Cymbalta vs. Lexapro

Cymbalta ndi Lexapro zimatha kuyambitsa zovuta zina, ngakhale zina zimakhala zotheka ndi m'modzi kapena wothandizirayo. Nausea, mwachitsanzo, imangotchulidwa mwa odwala 5% omwe amatenga Lexapro m'mayesero azachipatala motsutsana ndi 23% ya odwala omwe amatenga Cymbalta. Ngakhale kuti nseru sizikhala zotsatira zoyipa nthawi zonse, zimatha kukhudza moyo wamunthu. Zikuwoneka kuti zikuchitika m'masabata angapo oyamba amathandizidwe, ndipo popeza kuti mankhwalawa amatenga milungu iwiri kapena isanu ndi umodzi kuti awonetse kukhumudwa kapena zizindikiritso zakusokonekera, mseru ungakhale chifukwa chosiya kusadapezeke phindu lenileni la mankhwala amadziwika.

Thukuta, kapena thukuta, limachitika pamlingo wofanana pakati pa mankhwala awiriwa. Izi zimakhudzanso moyo wamunthu watsiku ndi tsiku komanso kudzidalira, ndipo mwina ndi chifukwa chomwe odwala amasankhira kusiya mankhwalawa.

Mndandanda wotsatirawu sikuti ukhale mndandanda wathunthu wazomwe zikuchitika. Chonde funsani wamankhwala, dokotala, kapena katswiri wina wazachipatala kuti mupeze mndandanda wazomwe zingachitike.

	Cymbalta	Kameme
Zotsatira zoyipa	Zoyenera?	Pafupipafupi	Zoyenera?	Pafupipafupi
Nseru	Inde	2. 3%	Inde	5%
Pakamwa pouma	Inde	13%	Inde	5%
Kutuluka thukuta	Inde	6%	Inde	5%
Kutsekula m'mimba	Inde	9%	Inde	8%
Kudzimbidwa	Inde	9%	Inde	3%
Dyspepsia	Ayi	n / A	Inde	3%
Chizungulire	Inde	9%	Ayi	n / A
Kusinza	Inde	10%	Inde	6%
Mutu	Inde	14%	Ayi	n / A
Kuchuluka kwa magazi	Inde	awiri%	Ayi	n / A
Kuchepetsa chilakolako	Inde	7%	Inde	3%
Kuchepetsa libido	Ayi	n / A	Inde	awiri%

Gwero: Cymbalta ( Tsiku ndi Tsiku ) Mpumi ( Tsiku ndi Tsiku )

Kuyanjana kwa mankhwala a Cymbalta vs. Lexapro

Cymbalta ndi Lexapro iliyonse imagwiritsidwa ntchito ndi ma cytochrome enzyme system m'chiwindi. Cymbalta ndi gawo lalikulu la CYP1A2, komanso choletsa pang'ono CYP2D6. Ndikofunika kudziwa kuti odwala ena amatha kudwala chifukwa cha kukhumudwa komanso nkhawa. Odwala ambiri omwe ali ndi vuto losamalira amathandizidwa ndi amphetamines. Cymbalta imatha kukulitsa kuchuluka kwa amphetamines kudzera mu kulepheretsa CYP2D6. Odwala omwe akuphatikiza izi ayenera kuyang'aniridwa bwino.

Lexapro ndi gawo lalikulu la CYP2C19 ndi CYP3A4, komanso choletsa chofooka cha CYP2D6.

Kugwiritsa ntchito Lexapro ndi tricyclic antidepressants, monga amitriptyline, kumatha kuwonjezera chiopsezo cha kutalikirana kwa QT ndi matenda a serotonin. Mwambiri, kuphatikiza uku kuyenera kupewedwa.

Mndandanda wotsatirawu sikuti ukhale mndandanda wathunthu wamagwiritsidwe azamankhwala. Ndibwino kuti mufunsane ndi omwe amakupatsirani kapena wamankhwala kuti mupeze mndandanda wathunthu.

Mankhwala osokoneza bongo	Gulu la mankhwala osokoneza bongo	Cymbalta	Kameme
Acalabrutinib Dabrafenib Erdafitinib Gilteritinib Anayankha	Antineoplastics	Inde	Inde
Almotriptan Eletriptan Oxitriptan	5HT Agonist / Triptans (othandizira ma antimigraine)	Inde	Inde
Amphetamine mchere Dexmethylphenidate Methylphenidate	Amphetamine	Inde	Inde
Alosetron Ondansetron Ramosetron	Otsutsa a 5HT3 (odana ndi nseru)	Ayi	Inde
Apixaban Edoxaban	Ma antiplatelet	Inde	Inde
Aripiprazole	Mankhwala oletsa antipsychotic	Inde	Inde
Asipilini Zamgululi Naproxen Diclofenac	Mankhwala osagwiritsidwa ntchito poletsa kutupa (NSAIDs)	Inde	Inde
Bemiparin Enoxaparin Heparin	Maantibayotiki	Ayi	Inde
Bupropion	Dopamine / norepinephrine reuptake inhibitor	Ayi	Inde
Buspirone	Kuda nkhawa	Inde	Inde
Carbamazepine	Wosakanikirana	Ayi	Inde
Enzalutamide	Chemotherapy wothandizila	Ayi	Inde
Esomeprazole Omeprazole	Proton pump inhibitor	Ayi	Inde
Fluconazole	Zosakanikirana	Ayi	Inde
Fluoxetine Duloxetine Paroxetine Sertraline	SSRIs	Inde	Inde
Hydroxychloroquine	Aminoquinolone / Antimalarial	Ayi	Inde
Mzere	Maantibayotiki	Inde	Inde
Metaxalone	Opumitsa minofu	Inde	Inde
Pimozide	Mankhwala oletsa antipsychotic	Ayi	Inde
Selegiline Phenelzine Rasagiline	Monoamine oxidase inhibitor (MAOI)	Inde	Inde
St. John's Wort	Mankhwala owonjezera azitsamba	Inde	Inde
Hydrochlorothiazide Chlorthalidone Metolazone	Odzetsa okodzetsa	Ayi	Inde
Zamgululi	Opiate ochepetsa ululu	Inde	Inde
Amitriptyline Clomipramine Doxepin Mzere wa Nortriptyline	Tricyclic antidepressants	Inde	Inde
Katemera	Kusankha norepinephrin / serotonin reuptake inhibitor (SNRIs)	Inde	Inde

Machenjezo a Cymbalta ndi Lexapro

Cymbalta ndi Lexapro sizipanga kuchotsedwa kwanthawi yomweyo kwa zodandaula kapena matenda amisala. Zitenga masabata osachepera awiri kuti muone kusintha kulikonse kwa odwala ambiri, komanso mpaka milungu inayi mpaka isanu ndi umodzi kuti muzindikire zotsatira zake. Ndikofunikira kuti odwala amvetsetse izi kuti asataye msanga mankhwala awo ndikukhulupirira kuti sikugwira ntchito.

Odwala omwe ali ndi MDD atha kukhala ndi vuto lakukhumudwa kapena malingaliro ofuna kudzipha kaya akumwa kapena ayi. Izi zitha kukulirakulira mpaka kukhululukidwa kukwaniritsidwa. Chithandizo cha Cymbalta ndi Lexapro chitha kukulitsa malingaliro ofuna kudzipha pakati pa achinyamata ndi achikulire, makamaka koyambirira kwa chithandizo chisanachitike. Odwalawa ayenera kuyang'aniridwa mosamala ngati mankhwalawa akuwoneka kuti ndi ofunikira. Kusintha kwamankhwala kumatha kukhala kofunikira ngati zizindikilo zayamba mwadzidzidzi kapena kukulira.

Pakhala pali malipoti a kulephera kwa chiwindi, nthawi zina amapha, ndi Cymbalta. Milanduyi imatha kubwera ndikumva kupweteka m'mimba komanso michere yayikulu ya chiwindi yokhala ndi jaundice kapena yopanda. Kumwa mowa kumatha kuwonjezera ngoziyi, chifukwa chake kuyenera kupewedwa.

Matenda a Serotonin amadziwika ndi ma SSRIs ndi SNRIs onse, kuphatikiza Cymbalta ndi Lexapro. Izi ndizomwe zimakhudzana ndi kuchuluka kwa serotonin ndipo zimatha kupangitsa wodwalayo kukhala wamanjenje, wamisala, komanso kuwonjezeka kwa mtima. Izi zitha kubweretsedwa pogwiritsa ntchito mankhwala awiri a serotonergic limodzi. Ndikofunika kutanthauzira zomwe wopanga amachita pokhudzana ndi mankhwala akamapereka mankhwalawa.

Mafunso omwe amafunsidwa kawirikawiri za Cymbalta vs. Lexapro

Kodi Cymbalta ndi chiyani?

Cymbalta ndi mankhwala ochepetsa kupanikizika omwe amagwiritsidwa ntchito pochiza kukhumudwa kwakukulu, matenda amisala wamba, ndi matenda osiyanasiyana am'mapapo ndi mafupa. Cymbalta imapezeka ngati kapisozi wamlomo mu 20 mg, 30 mg, ndi mphamvu za 60 mg.

Lexapro ndi chiyani?

Lexapro ndi mankhwala ochepetsa nkhawa omwe amagwiritsidwa ntchito pochiza kukhumudwa kwakukulu komanso matenda amisala. Lexapro imapezeka ngati piritsi la 5 mg, 10 mg, ndi mphamvu za 20 mg. Ikupezekanso ngati yankho lamlomo.

Kodi Cymbalta ndi Lexapro ali ofanana?

Ngakhale onse a Cymbalta ndi Lexapro amathandizira kukhumudwa ndi nkhawa, sizofanana. Cymbalta imatseka kubwezeretsanso kwa serotonin ndi norepinephrine mu neuronal synapse, pomwe Lexapro imatchinga serotonin reuptake yokha. Cymbalta imakhala ndi ziwonetsero zina zowonjezereka zopweteka.

Kodi Cymbalta kapena Lexapro ndibwino?

Cymbalta ndi Lexapro zimawoneka ngati zofanananso pochiza kukhumudwa. Kusanthula kwakukulu kwa meta kwamaphunziro angapo kukuwonetsa kuti kuchuluka kwakukulu kwa zovuta ndi Cymbalta kungakhale chifukwa choyesera Lexapro choyamba mwa odwala ambiri.

Kodi ndingagwiritse ntchito Cymbalta kapena Lexapro ndili ndi pakati?

Food and Drug Administration (FDA) imaganizira za mtundu wa Cmbalta ndi Lexapro wokhala ndi pakati C, kutanthauza kuti sipanakhale maphunziro okwanira aanthu kuti athetse chitetezo. Ndi Cymbalta, zotsatira zosakhala za teratogenic zawonedwa mwa ana akhanda kutsatira kuyang'anira kwa Cymbalta ali ndi pakati. Izi zimaphatikizapo kupuma, kupuma movutikira, ndi kunjenjemera. Pogwiritsa ntchito Lexapro, maphunziro a nyama awonetsa zotsatira za teratogenic kwa mwana wosabadwayo, kuphatikiza zamtima, ndipo zatsimikizika kuti imadutsa placenta ya munthu. Pazifukwa izi, kugwiritsa ntchito Cymbalta kapena Lexapro panthawi yoyembekezera kuyenera kuyezedwa kuti kungavulaze mwana wosabadwayo.

Kodi ndingagwiritse ntchito Cymbalta kapena Lexapro ndi mowa?

Mowa umatha kuwonjezera zoopsa za Cymbalta ndi Lexapro. Kumwa mowa ndikumwa mankhwalawa kumatha kuyambitsa vuto lalikulu la psychomotor, ndipo pachifukwa ichi, odwala amalangizidwa kuti asamamwe mowa ngati atenga Cymbalta kapena Lexapro. Monga tafotokozera kale, kumwa mowa uli pa Cymbalta kumawonjezera mwayi wakulephera kwa chiwindi.

Kodi Cymbalta imathandiza ndi nkhawa?

Cymbalta imavomerezedwa pochiza matenda amisala wamba. Odwala ayenera kuphunzitsidwa kuti mankhwalawa sangathetseretu nkhawa, ndipo odwala ena angafunike mankhwala owonjezera pazovuta zazikulu.

Kodi Cymbalta imakusangalatsani?

Cymbalta imagwira ntchito powonjezera norepinephrine ndi serotonin. Ma neurotransmitters awa amatenga gawo lofunikira pakusintha kapena kukhudza. Odwala omwe amatenga Cymbalta atha kunena kuti akumva kukhala osangalala kapena ochepetsedwa, makamaka atalandira chithandizo kwa milungu inayi kapena isanu ndi umodzi.

Kodi Cymbalta imasintha umunthu wanu?

Cymbalta idzakhudza mitima yanu powonjezera norepinephrine ndi serotonin. Kwa odwala ambiri, izi zimapangitsa kusintha kwamaganizidwe awo. Mukawona kusintha kolakwika mwa inu nokha kapena munthu amene mumamukonda mukamatenga Cymbalta, kuphatikizapo malingaliro ofuna kudzipha kapena malingaliro, funsani thandizo mwachangu.