Symbicort vs. Advair: Kusiyana, kufanana, ndi zomwe zili zabwino kwa inu
Mankhwala osokoneza bongo Vs. MnzanuKuwunika kwa mankhwala osokoneza bongo & kusiyana kwakukulu | Zinthu zothandizira | Mphamvu | Kuphunzira inshuwaransi ndikufanizira mtengo | Zotsatira zoyipa | Kuyanjana kwa mankhwala | Machenjezo | FAQ
Symbicort ndi Advair ndi mankhwala awiri omwe amagwiritsidwa ntchito pochizira mphumu ndi matenda osokoneza bongo (COPD). Mphumu ndi COPD ndizomwe zimakhudza mapapu ndipo zimayambitsa kutupa munjira za mpweya. Zizindikiro za mphumu ndi COPD zimaphatikizapo kupuma movutikira, kupuma, ndi kutsokomola.
Symbicort ndi Advair ndi ma inhalers okonza omwe amaphatikiza corticosteroid (ICS) yokhala ndi agonist wa nthawi yayitali wa beta (LABA). Ma inhalers awa amagwiritsidwa ntchito tsiku lililonse kuti athetse kutupa m'mapapu ndikusunga mpweya kutseguka. Sagwiritsidwe ntchito ngati opulumutsa inhalers pazizindikiro zazikulu za mphumu kapena COPD. Ngakhale amafanana, Symbicort ndi Advair ali ndi zosiyanazi pazomwe zimagwiritsidwa ntchito komanso mlingo woyenera.
Kodi pali kusiyana kotani pakati pa Symbicort ndi Advair?
Symbicort ndi Advair zili ndi corticosteroid, yomwe imakhala ndi zotsatira zotsutsana ndi zotupa m'mapapu. Symbicort ili ndi corticosteroid budesonide pomwe Advair ili ndi corticosteroid fluticasone. Symbicort ndi Advair imakhalanso ndi bronchodilator yotenga nthawi yayitali, yomwe imathandizira kuti mayendedwe apansi atseguke; Symbicort ili ndi formoterol pomwe Advair ili ndi salmeterol.
Symbicort imagwiritsidwa ntchito ngati chithandizo cha COPD, ndipo chitha kugwiritsidwa ntchito pochizira mphumu mwa anthu azaka 6 kapena kupitilira apo. Advair imagwiritsidwanso ntchito ngati chithandizo chothandizira COPD, ndipo chitha kugwiritsidwa ntchito pochizira mphumu mwa anthu azaka 4 kapena kupitilira apo. Mlingo woyenera wa Symbicort ndimapumidwe awiri kawiri tsiku lililonse pomwe mulingo wa Advair umapumira kamodzi kawiri patsiku.
Symbicort imabwera ngati inhalation aerosol yokhala ndi mphamvu ya 80 / 4.5 mcg kapena 160 / 4.5 mcg ya budesonide / formoterol. Advair imapezeka ngati inhalation aerosol ndi powder inhalation, koma inhalation aerosol imavomerezedwa kokha kuchiza mphumu pomwe ufa wa inhalation umatha kuchiza mphumu ndi COPD. Advair HFA ndi metered-inhaler yomwe imatulutsa mpweya wopatsa mphamvu mu 45/21 mcg, 115/21 mcg, kapena 230/21 mcg ya fluticasone / salmeterol. Advair Diskus imapereka ufa wopumira ndi mphamvu ya 100/50 mcg, 250/50 mcg, kapena 500/50 mcg ya fluticasone / salmeterol.
| Kusiyana kwakukulu pakati pa Symbicort ndi Advair | ||
|---|---|---|
| Chizindikiro | Advair | |
| Gulu la mankhwala osokoneza bongo | ICS (inhaled corticosteroid) ndi LABA (wautali wa beta2-adrenergic agonist) | ICS (inhaled corticosteroid) ndi LABA (wautali wa beta2-adrenergic agonist) |
| Chizindikiro cha Brand / generic | Ma brand ndi generic amapezeka | Ma brand ndi generic amapezeka |
| Kodi dzina lachibadwa ndi liti? | Budesonide ndi formoterol fumarate dihydrate | Fluticasone propionate ndi salmeterol |
| Kodi mankhwalawa amabwera mwa mawonekedwe ati? | Inhalation aerosol (metered-dose inhaler) | Inhalation aerosol (metered-dose inhaler) Kutulutsa mpweya (diskus) |
| Kodi mulingo woyenera ndi uti? | Chithandizo cha mphumu mwa odwala azaka 12 kapena kupitilira apo: Inhalations 2 ya Symbicort 80 / 4.5 kapena 160 / 4.5 kawiri tsiku lililonse Chithandizo cha mphumu mwa odwala azaka 6 mpaka ochepera zaka 12: Inhalations 2 ya Symbicort 80 / 4.5 kawiri tsiku lililonse Kusamalira chithandizo cha COPD: Inhalations 2 ya Symbicort 160 / 4.5 kawiri tsiku lililonse | Sakanizani Diskus Chithandizo cha mphumu mwa odwala azaka 12 kapena kupitilira apo: 1 inhalation ya Advair Diskus 100/50, 250/50, kapena 500/50 kawiri tsiku lililonse Chithandizo cha mphumu mwa odwala azaka zapakati pa 4 mpaka 11 wazaka: 1 inhalation ya Advair Diskus 100/50 kawiri tsiku lililonse Kusamalira chithandizo cha COPD: 1 inhalation ya Advair Diskus 250/50 kawiri tsiku lililonse Advair HFA |
| Kodi mankhwalawa amatenga nthawi yayitali bwanji? | Kutalika | Kutalika |
| Ndani amagwiritsa ntchito mankhwalawa? | Akuluakulu ndi ana azaka 6 kapena kupitilira apo | Akuluakulu ndi ana azaka 4 kapena kupitilira apo |
Zomwe zimathandizidwa ndi Symbicort ndi Advair
Symbicort ndi Advair onse ndi ovomerezeka ndi FDA kuti athetse mphumu ndi COPD. Komabe, Advair Diskus imavomerezedwa kuchiza mphumu ndi COPD pomwe Advair HFA imangovomerezedwa kuchiza mphumu. Symbicort ndi Advair amagwiritsidwa ntchito ngati mankhwala opangira ma inhalers omwe amagwiritsidwa ntchito tsiku ndi tsiku kuwongolera ndi kupewa COPD ndi zizindikiro za mphumu, monga kupuma pang'ono komanso kupuma.
Mukamagwiritsa ntchito nthawi yayitali, mankhwalawa amathanso kuthandiza kuchepetsa kukula kwa pafupipafupi kwa COPD komanso matenda a mphumu , kapena kukulitsa. Pofuna kuthana ndi zovuta zaposachedwa za COPD kapena mphumu, wothandizira zaumoyo amakupatsani mankhwala opulumutsa ngati albuterol, omwe amadziwika ndi mayina odziwika ngati Ventolin ndi ProAir.
| Mkhalidwe | Chizindikiro | Advair |
| Mphumu | Inde | Inde |
| COPD | Inde | Inde |
Kodi Symbicort kapena Advair ndiyothandiza kwambiri?
Onse Symbicort ndi Advair ndi ma inhalers othandiza akagwidwa mosasintha. Zonsezi zimakhala ndi zinthu zofananira zomwe zimathandizira kuchepetsa kutupa m'mapapu ndikutsegula mayendedwe apansi. Lankhulani ndi wothandizira zaumoyo kuti mupeze mankhwala abwino kwambiri omwe amakuthandizani.
Malinga ndi a kusanthula meta , inhaler yokhala ndi corticosteroid yolembetsedwa komanso bronchodilator yanthawi yayitali imathandizira kuchepetsa kuchuluka kwa COPD kuposa inhaler yokhala ndi bronchodilator yanthawi yayitali. Palibe mayesero am'mutu ndi mutu omwe amafanizira mwachindunji zomwe zimagwiritsidwa ntchito mu Symbicort ndi Advair zomwe zidawunikiridwa pakuwunika. Komabe, kafukufukuyu adapeza kuti, makamaka, kuphatikiza ma inhalers kumathandizanso chimodzimodzi.
Kuyesa kwamankhwala kosawoneka bwino, kosawona kawiri kunapeza kuti zopangira mu Symbicort ndi Advair zimapereka kusintha komweko mu ntchito yamapapu, masiku olamulira mphumu, ndi moyo wokhudzana ndi mphumu. Mankhwala onsewa amachepetsanso chiopsezo chogona kuchipatala kapena kuyendera zipinda zamwadzidzidzi zomwe zimayamba chifukwa cha kukulira kwa zizindikiro za mphumu. Kafukufukuyu adachitika pa anthu 2,866 azaka 16 kapena kupitilira apo.
Kuphatikiza ndi kuyerekezera mtengo kwa Symbicort vs. Advair
Symbicort nthawi zambiri imakhala ndi Medicare komanso mapulani a inshuwaransi. Imapezekanso ngati mankhwala achibadwa, omwe angakhale otsika mtengo kusiyana ndi mtundu wamaina. Mtengo wapakati wogulitsa wa Symbicort ndi pafupifupi $ 550. Mutha kugula Symbicort pafupifupi $ 250 ndi pulogalamu yosungira kapena khadi yotsitsa, ngati khadi ya SingleCare.
Advair imapezekanso ndi Medicare ndi mapulani a inshuwaransi. Monga Symbicort, Advair imabwera mu mawonekedwe achibadwa. Poyerekeza ndi Symbicort, mitengo yamalonda yamalonda ya Advair HFA itha kukhala yokwera pafupifupi $ 584. Mtengo wapakati wa Advair Diskus ndi pafupifupi $ 494. Mutha kusunga pamtengo wa Advair HFA kapena Advair Diskus ndi khadi limodzi la Coupon ku ma pharmacies omwe akutenga nawo mbali.
| Chizindikiro | Advair | |
| Nthawi zambiri amakhala ndi inshuwaransi? | Inde | Inde |
| Nthawi zambiri amakhala ndi Medicare Part D? | Inde | Inde |
| Kuchuluka | 1 inhaler | 1 inhaler |
| Wopanga Medicare wamba | $ 19- $ 399 | $ 2- $ 425 |
| Mtengo wosakwatiwa | $ 248 + | $ 288 + |
Zotsatira zoyipa za Symbicort vs. Advair
Symbicort ndi Advair onse amakhala ndi zovuta zofananira. Mankhwala onsewa amatha kuyambitsa mavuto monga kupweteka mutu, nasopharyngitis, matenda opatsirana opuma, bronchitis, ndi kuchulukana kwammphuno. Zotsatira zina zimatha kukhala ndi nseru, kusanza, kuuma, ndi kupweteka msana.
Gawo la steroid la Symbicort ndi Advair limatha kuonjezera chiwopsezo chakumwa mkamwa, kapena matenda am'fungulu mkamwa. Pachifukwa ichi, ndikofunikira kutsuka mkamwa ndi madzi mutagwiritsa ntchito inhaler. Chida chotchedwa spacer chitha kuphatikizidwanso ndi ma inhalers a metered kuti athandize kuchepetsa chiopsezo chakumwa mkamwa.
Zotsatira zoyipa zoyipa za mankhwala a ICS / LABA zimaphatikizapo paradoksic bronchospasm ndi anaphylaxis. Zomwe zimayambitsa bronchospasm yodabwitsa sizimveka bwino. Komabe, zimatha kuchitika modzidzimutsa, kupuma pang'ono, ndi kutsokomola mutagwiritsa ntchito mankhwala opumira. Anaphylaxis imatha kuchitika chifukwa cha zovuta zina zilizonse mu Symbicort kapena Advair. Funsani chithandizo chamankhwala mwachangu mukakumana ndi zotupa zazikulu, kutupa, kapena kupuma movutikira mutagwiritsa ntchito inhaler.
| Chizindikiro | Advair | |||
| Zotsatira zoyipa | Zoyenera? | Pafupipafupi | Zoyenera? | Pafupipafupi |
| Mutu | Inde | 7% | Inde | 12% |
| Nasopharyngitis | Inde | khumi ndi limodzi% | Inde | * |
| Matenda opatsirana apamwamba | Inde | 8% | Inde | 27% |
| Matenda | Inde | 5% | Inde | awiri% |
| Kuchulukana m'mphuno | Inde | 3% | Inde | * |
| Kutulutsa pakamwa | Inde | 1% | Inde | 1% |
| Nseru | Inde | * | Inde | 4% |
| Kusanza | Inde | 1% | Inde | 4% |
| Kuopsa | Inde | * | Inde | 5% |
| Ululu wammbuyo | Inde | 3% | Inde | * |
* sananene
Pafupipafupi sizidalira zomwe zimayesedwa pamutu. Izi sizingakhale mndandanda wathunthu wazovuta zomwe zingachitike. Chonde onani dokotala wanu kapena wothandizira zaumoyo kuti mudziwe zambiri.
Gwero: DailyMed ( Chizindikiro ), Tsiku Lililonse ( Advair )
Kuyanjana kwa mankhwala a Symbicort vs. Advair
Chenjezo limalangizidwa mukamagwiritsa ntchito Symbicort kapena Advair ndi mankhwala omwe ali CYP3A4 inhibitors, monga ritonavir, ketoconazole, ndi clarithromycin. Kutenga choletsa CYP3A4 yokhala ndi Symbicort kapena Advair kungayambitse kuchuluka kwa magazi m'chigawo cha corticosteroid, chomwe chitha kubweretsa zovuta.
Kugwiritsa ntchito monoamine oxidase inhibitors (MAOIs) kapena tricyclic antidepressants okhala ndi Symbicort kapena Advair kumatha kukulitsa mavuto amtima ndi gawo la beta-agonist mu mankhwala aliwonse. Kumbali inayi, ma beta blockers amathanso kuchepa zotsatira za beta-agonist m'mapapu. Ma diuretics amatha kuyambitsa kusintha kwama electrocardiographic kapena potaziyamu wochepa (hypokalemia) akagwiritsidwa ntchito ndi Symbicort kapena Advair.
| Mankhwala osokoneza bongo | Gulu la mankhwala osokoneza bongo | Chizindikiro | Advair |
| Ritonavir Atazanavir Ketoconazole Clarithromycin Indinavir Chinthaka Nefazodone Nelfinavir Saquinavir | CYP3A4 zoletsa | Inde | Inde |
| Selegiline Rasagiline Phenelzine Isocarboxazid | Monoamine oxidase inhibitors (MAOIs) | Inde | Inde |
| Amitriptyline Mzere wa Nortriptyline | Tricyclic antidepressants | Inde | Inde |
| Zamgululi Atenolol Bisoprolol Nebivolol Zamgululi | Oletsa Beta | Inde | Inde |
| Furosemide Bumetanide Torsemide Chlorthalidone | Okodzetsa | Inde | Inde |
Funsani katswiri wa zamankhwala pazinthu zina zomwe zingachitike ndi mankhwala.
Machenjezo a Symbicort ndi Advair
Chifukwa ali ndi corticosteroid, Symbicort ndi Advair zitha kuyambitsa chiopsezo chowonjezeka cha matenda opatsirana kapena kuchepa kwa mchere wamafupa. Komabe, poyerekeza ndi systemic corticosteroids, inhaled corticosteroids imakhala pachiwopsezo chotsika cha zotsatirazi. Kuponderezedwa kwa adrenal kumathanso kuchitika mukamagwiritsa ntchito Mlingo waukulu wa Symbicort kapena Advair.
Kugwiritsa ntchito Symbicort kapena Advair kwa nthawi yayitali kumawonjezera ngozi ya glaucoma kapena ng'ala. Katswiri wa maso angafunikire kufunsidwa ngati zizindikiro zamaso zikukula pakapita nthawi ndi kugwiritsa ntchito mankhwalawa.
Kugwiritsiridwa ntchito kwa Symbicort kapena Advair kuyenera kuyang'aniridwa kwa odwala omwe ali ndi vuto la mtima, mitsempha yapakatikati yamanjenje, zovuta zamafupa, komanso matenda ashuga. Lankhulani ndi wothandizira zaumoyo kuti akuchenjezeni ndi kusamala musanagwiritse ntchito Symbicort kapena Advair.
Mafunso omwe amafunsidwa pafupipafupi za Symbicort vs. Advair
Kodi Symbicort ndi chiyani?
Symbicort ndi mankhwala odziwika bwino omwe amapangidwa ndi AstraZeneca. Lili ndi budesonide ndi formoterol, zomwe zimathandiza kupewa ndikuwongolera zizindikiritso za mphumu ndi COPD. Symbicort imavomerezedwa kuchiza mphumu mwa odwala azaka 6 kapena kupitilira apo. Imapezeka ngati mpweya wopumira womwe umagwiritsidwa ntchito kawiri tsiku lililonse.
Advair ndi chiyani?
Advair ndi dzina lodziwika bwino lopangidwa ndi GlaxoSmithKline. Lili ndi fluticasone ndi salmeterol. Advair ndi FDA yovomerezeka kuti iteteze ndikuwongolera zizindikiro za COPD ndi mphumu. Amaloledwa kuchiza mphumu mwa odwala azaka 4 kapena kupitilira apo. Advair imapezeka ngati ufa wopumira (Advair Diskus), womwe umatha kuchiza mphumu ndi COPD, komanso mpweya wopumira (Advair HFA), womwe umavomerezedwa kuchiza mphumu. Zonsezi zimagwiritsidwa ntchito kawiri tsiku lililonse.
Kodi Symbicort ndi Advair ndizofanana?
Symbicort ndi Advair amagwiritsidwa ntchito pochizira mphumu ndi COPD. Komabe, ali ndi zosakaniza zosiyanasiyana. Symbicort imakhala ndi budesonide ndi formoterol pomwe Advair ili ndi fluticasone ndi salmeterol. Symbicort imatha kuchiza mphumu mwa odwala azaka 6 kapena kupitilira pomwe Advair amatha kuchiza mphumu mwa odwala azaka 4 kapena kupitilira apo. Advair imapezekanso ngati ufa wopumira kapena aerosol pomwe Symbicort imangopezeka ngati mpweya wopumira.
Kodi Symbicort kapena Advair ndibwino?
Onse Symbicort ndi Advair ndi othandiza pochiza COPD ndi zizindikiro za mphumu. Chifukwa ndi mankhwala osamalira, ayenera kugwiritsidwa ntchito tsiku lililonse kuti zitheke. Njira yabwino yosamalira inhaler iyenera kutsimikizika poganizira zinthu monga zoyipa zomwe zingachitike, kuchuluka kwake, ndi mtengo wake.
Kodi nditha kugwiritsa ntchito Symbicort kapena Advair ndili ndi pakati?
Palibe kafukufuku wokwanira wonena kuti Symbicort kapena Advair ndiotetezeka kapena yovulaza panthawi yapakati. Malinga ndi Asthma and Allergy Foundation of America (AAFA), agonists omwe akhala akugwira ntchito kwa nthawi yayitali ali osavomerezeka monga chithandizo choyamba cha mphumu mwa odwala omwe ali ndi pakati. M'malo mwake, bronchodilator yochita kwakanthawi akhoza kulimbikitsidwa m'malo mwake. Funsani othandizira azaumoyo kuti akalandire upangiri wa zamankhwala pa COPD ndi chithandizo cha mphumu mukakhala ndi pakati.
Kodi ndingagwiritse ntchito Symbicort kapena Advair ndi mowa?
Mowa sadziwika kuti ungagwirizane ndi Symbicort kapena Advair. Kumwa mowa mwauchidakwa kungasokoneze chitetezo cha mthupi chothana ndi matenda, omwe amatha kukula chifukwa cha kuwonjezeka kwa mphumu kapena COPD. Lankhulani ndi wothandizira zaumoyo ngati zili bwino kumwa mowa mukamagwiritsa ntchito Symbicort kapena Advair.
Kodi inhaler ndi yofanana bwanji ndi Symbicort?
Mtundu wa Symbicort ulipo. Mtundu wa generic, womwe uli ndi budesonide ndi formoterol, ndi wofanana ndi Symbicort. Mtundu wa generic amathanso kukhala wotsika mtengo m'malo mwa dzina la inhaler. Inhalers yofananira ndi Symbicort ndi Advair (fluticasone / salmeterol), Dulera (mometasone / formoterol), ndi Breo (fluticasone / vilanterol). Ma inhalers awa atha kugwira ntchito chimodzimodzi ndi Symbicort, koma samawerengedwa kuti ndi ofanana ndi Symbicort.
Kodi inhaler yotetezeka kwambiri ndi COPD ndi iti?
Mankhwala osakaniza a ICS / LABA amaonedwa kuti ndi othandiza komanso otetezeka pochiza COPD. Komabe, kupuma kwa corticosteroids kumawonjezera chiwopsezo cha chibayo mwa anthu omwe ali ndi COPD yayikulu. LAMA / LABA kuphatikiza ma inhalers kumawerengedwa kuti ndi othandiza komanso otetezeka kuposa ICS / LABA kuphatikiza ma inhalers pachifukwa ichi. Mankhwala ophatikizira a LAMA / LABA ndi Anoro (umeclidinium / vilanterol), Stiolto (tiotropium / olodaterol), ndi Bevespi (glycopyrrolate / formoterol).
