Crestor vs. Lipitor: Kusiyana, kufanana, ndi zomwe zili zabwino kwa inu
Mankhwala osokoneza bongo Vs. MnzanuKuwunika kwa mankhwala osokoneza bongo & kusiyana kwakukulu | Zinthu zothandizira | Mphamvu | Kuphunzira inshuwaransi ndi kufananiza mtengo | Zotsatira zoyipa | Kuyanjana kwa mankhwala | Machenjezo | FAQ
Malinga ndi Centers for Disease Control and Prevention (CDC), pafupifupi 38% ya achikulire ku US ali ndi cholesterol yambiri. Ngati muli ndi mafuta ambiri m'thupi, dokotala wanu angakulangizeni za kufunika kodya ndi kuchita masewera olimbitsa thupi. Dokotala wanu atha kutchulanso za kuyamba mankhwala a statin. Statins ndi mankhwala odziwika bwino, omwe amadziwikanso kuti HMG-CoA reductase inhibitors. Amagwira ntchito poletsa enzyme (yotchedwa HMG-CoA reductase) yomwe thupi lanu liyenera kupanga cholesterol.
Crestor ndi Lipitor ndi ma statin awiri odziwika bwino omwe amagwiritsidwa ntchito kutsitsa cholesterol. Mankhwala onsewa amavomerezedwa ndi US Food and Drug Administration (FDA). Amagwiritsidwa ntchito limodzi ndi zakudya zopanda mafuta okhutira ndi cholesterol kuti muchepetse cholesterol. Ngakhale Crestor ndi Lipitor onse ndi ma statins, si ofanana. Pitilizani kuwerenga kuti mudziwe zambiri za Crestor ndi Lipitor.
Kodi pali kusiyana kotani pakati pa Crestor ndi Lipitor?
Crestor (Crestor ndi chiyani?) Ndi Lipitor (Kodi Lipitor ndi chiyani?) Onsewa ndi mankhwala ochepetsa lipid. Amadziwikanso kuti statins, kapena HMG-CoA reductase inhibitors. Mankhwala onsewa amapezeka motulutsa mawonekedwe komanso generic komanso mapiritsi okha. AstraZeneca imapanga Crestor yotchedwa Crestor, ndipo Pfizer imadzipangira dzina loti Lipitor. Crestor ndi Lipitor zimagwiritsidwa ntchito makamaka kwa akulu; komabe, nthawi zina, atha kugwiritsidwa ntchito mwa ana.
| Kusiyana kwakukulu pakati pa Crestor ndi Lipitor | ||
|---|---|---|
| Crestor | Lipitor | |
| Gulu la mankhwala osokoneza bongo | HMG-CoA reductase inhibitor (yomwe imadziwikanso kuti statin kapena lipid-lowering agent) | HMG-CoA reductase inhibitor (yomwe imadziwikanso kuti statin kapena lipid-lowering agent) |
| Chizindikiro cha Brand / generic | Brand ndi generic | Brand ndi generic |
| Kodi dzina lachibadwa ndi liti? | Rosuvastatin | Atorvastatin |
| Kodi mankhwalawa amabwera mwa mawonekedwe ati? | Piritsi | Piritsi |
| Kodi mulingo woyenera ndi uti? | Chitsanzo: 10 mg tsiku lililonse | Chitsanzo: 20 mg tsiku lililonse |
| Kodi mankhwalawa amatenga nthawi yayitali bwanji? | Kutalika | Kutalika |
| Ndani amagwiritsa ntchito mankhwalawa? | Akuluakulu; ana azaka 7 kapena kupitilira apo (nthawi zina) | Akuluakulu; ana azaka 10 kapena kupitilira apo (nthawi zina) |
Zomwe amathandizidwa ndi Crestor ndi Lipitor
Crestor ndi Lipitor amagwiritsidwa ntchito kuchepetsa cholesterol. Crestor kapena Lipitor iyenera kugwiritsidwa ntchito, pamodzi ndi zakudya zopanda mafuta ambiri ndi cholesterol, pomwe chakudya chokha sichinagwire bwino ntchito kuchepetsa cholesterol. Crestor ndi Lipitor m'munsi cholesterol chonse, LDL, ApoB, ndi triglycerides . Amawonjezeranso cholesterol ya HDL, mtundu wabwino wa cholesterol.
Zisonyezero zina zalembedwa mchati pansipa. Crestor ndi Lipitor sanaphunzirepo pochiza a Fredrickson Type I ndi V dyslipidemias.
| Mkhalidwe | Crestor | Lipitor |
| Hyperlipidemia komanso dyslipidemia mwa akulu | Inde | Inde |
| Wodziwika Hypercholesterolemia mwa ana | Inde | Inde |
| Hypertriglyceridemia mwa akulu | Inde | Inde |
| Ma dysbetalipoproteinemia oyambira (Type III hyperlipoproteinemia) mwa akulu | Inde | Inde |
| Homozygous banja hypercholesterolemia mwa akulu | Inde | Inde |
| Kuchepetsa kupita patsogolo kwa atherosclerosis mwa akulu | Inde | Inde |
| Kupewa matenda amtima (matenda amtima, matenda amtima) | Inde | Inde |
Kodi Crestor kapena Lipitor ndiyothandiza kwambiri?
Ofufuzawo anayerekezera ma statin angapo pamayeso azachipatala otchedwa Mayeso okhazikika (Statin Therapies for okwera kwa Lipid Levels Poyerekeza Ponse pa Mlingo ndi Rosuvastatin). Adayang'ana zotsatira za Lipitor, Crestor, Zocor, ndi Pravachol pakutsitsa LDL (low-density lipoprotein) cholesterol pambuyo pa milungu isanu ndi umodzi.
Kafukufukuyu adatsimikiza kuti Crestor adatsitsa LDL cholesterol ndi 8.2% kuposa Lipitor, ndipo Crestor adatsitsa cholesterol yathunthu kwambiri kuposa ma statins ena onse omwe adaphunzira. Crestor idakulitsanso cholesterol ya HDL (mtundu wabwino wama cholesterol) kuposa Lipitor. Odwala omwe adatenga Crestor, kutengera kuchuluka kwa mankhwala, 82-89% adakwaniritsa zolinga za LDL cholesterol, poyerekeza ndi 69-85% ya odwala omwe adatenga Lipitor. Ma statins onse adalekerera chimodzimodzi.
Kafukufuku wina wotchedwa SATURN kuyesedwa (Study of Coronary Atheroma by Intravascular Ultrasound: Zotsatira za Rosuvastatin motsutsana ndi Atorvastatin) adayang'ana Mlingo wambiri wa Crestor-40 mg tsiku lililonse ndi Lipitor 80 mg tsiku ndi tsiku-komanso momwe zimakhudzira kukula kwa matenda a mitsempha yotchedwa coronary atherosclerosis. Coronary atherosclerosis ndikuchepa kwa mitsempha yamagazi komanso kuchuluka kwa calcium ndi mafuta m'mitsempha, zomwe zimapangitsa kuti magazi asafike pamtima, ndikuwonjezera chiopsezo cha matenda amtima.
Kafukufukuyu adawunikiranso za chitetezo ndi zoyipa. Pambuyo pazaka ziwiri zopitilira muyeso, gulu la Crestor linali ndi magawo ochepa a LDL komanso ma HDL ochepa kuposa gulu la Lipitor. (Ngakhale, kungakhale koyenera kudziwa kuti AstraZeneca, wopanga Crestor, adathandizira phunziroli. Komanso, mankhwalawa amaperekedwa pamlingo waukulu kwambiri, womwe siofala kuchipatala kwa wodwala wamba.) Crestor ndi Lipitor adalimbikitsa regression of atherosclerosis pamlingo wofanana. Mankhwala onsewa anali olekerera ndipo anali ndi zovuta zochepa labu.
M'madera azachipatala, mankhwala onsewa amalembedwa komanso kulekerera. Mankhwala othandiza kwambiri kwa inu akhoza kutsimikiziridwa ndi omwe amakuthandizani azaumoyo, omwe angaganizire zaumoyo wanu, mbiri yanu, ndi mankhwala omwe mumamwa omwe amatha kulumikizana ndi Crestor kapena Lipitor.
Kuphunzira ndi kuyerekezera mtengo wa Crestor vs. Lipitor
Crestor kapena Lipitor amakhala ndi inshuwaransi yambiri komanso mapulani a Medicare mumitundu yawo ya rosuvastatin kapena atorvastatin. Kusankha dzina la dzina lake kumatha kubweretsa kopayi yayikulu kapena mwina sikungaphimbidwe.
Patsamba la 30, 10 mg mapiritsi a rosuvastatin (generic Crestor), mtengo wakuthumba ungakhale pafupifupi $ 134. Mutha kugwiritsa ntchito coupon yaulere ya SingleCare kuti muchepetse mtengo mpaka $ 11 kuma pharmacies omwe akutenga nawo mbali.
Mankhwala wamba a 30, 20 mg mapiritsi a atorvastatin (generic Lipitor) amatha ndalama pafupifupi $ 82 ngati mutalipira m'thumba. Coupon ya singleCare generic Lipitor ikhoza kubweretsa mtengo mpaka pafupifupi $ 15.
Momwe mapulani amasinthira komanso amatha kusintha, lemberani kampani yanu ya inshuwaransi kuti mumve zambiri za Crestor ndi Lipitor.
| Crestor | Lipitor | |
| Nthawi zambiri amakhala ndi inshuwaransi? | Inde (generic) | Inde (generic) |
| Nthawi zambiri amakhala ndi Medicare Part D? | Inde (generic) | Inde (generic) |
| Kuchuluka | Chitsanzo: 30, 10 mg mapiritsi | Chitsanzo: 30, 20 mg mapiritsi |
| Wopanga Medicare wamba | $ 0- $ 20 | $ 0- $ 15 |
| Mtengo wosakwatiwa | $ 11 + | $ 15 + |
Pezani khadi yotsitsa ya SingleCare
Zotsatira zoyipa za Crestor vs. Lipitor
Zotsatira zoyipa kwambiri za Crestor ndi kupweteka mutu, kupweteka kwa minofu, kupweteka m'mimba, nseru, ndi kufooka.
Zotsatira zoyipa kwambiri za Lipitor ndi chimfine, kupweteka kwa mafupa, kutsekula m'mimba, kupweteka kumapeto, ndi matenda am'mikodzo.
Zotsatira zosowa koma zoyipa za Crestor ndi Lipitor ndi myopathy (kufooka kwa minofu) ndi rhabdomyolysis (kuwonongeka kwa minofu yaminyewa, yomwe imatha kukhala yowononga kwambiri). Onani gawo lochenjeza kuti mumve zambiri.
Zomwe zimayambitsa zotsatirapo zimatha kusiyanasiyana ndi kuchuluka kwa mankhwala. Ili si mndandanda wathunthu wazotsatira. Zina, zovuta zoyipa zimatha kuchitika. Lankhulani ndi omwe akukuthandizani zaumoyo pazovuta zomwe mungayembekezere kuchokera ku Crestor kapena Lipitor, ndi momwe mungazithetsere.
| Crestor | Lipitor | |||
| Zotsatira zoyipa | Zoyenera? | Pafupipafupi | Zoyenera? | Pafupipafupi |
| Mutu | Inde | 5.5% | Ayi | - |
| Nseru | Inde | 3.4% | Inde | 4% |
| Kupweteka kwa minofu / kupweteka | Inde | 2.8% | Inde | 3.8% |
| Ululu wophatikizana | Inde | Zimasintha | Inde | 6.9% |
| Ululu kumapeto | Ayi | - | Inde | 6% |
| Matenda a mkodzo | Ayi | - | Inde | 5.7% |
| Kufooka | Inde | 2.7% | Inde | 6.9% |
| Kudzimbidwa | Ayi | - | Inde | 4.7% |
| Kudzimbidwa | Inde | 2.4% | Ayi | - |
| Kutsekula m'mimba | Ayi | - | Inde | 6.8% |
| Kupweteka m'mimba | Inde | ≥2% | Inde | % sananene |
| Chimfine | Ayi | - | Inde | 8.3% |
Gwero: DailyMed ( Crestor ), Tsiku Lililonse ( Lipitor )
Kuyanjana kwa mankhwala a Crestor vs. Lipitor
Chofunika kuchita ndi Lipitor ndikuti simuyenera kumwa madzi amphesa ochulukirapo (opitilira 1.2 malita patsiku). Madzi amphesa ochulukirapo amatha kukulitsa kuchuluka kwa Lipitor mthupi lanu, kukupangitsani kuti mukhale ndi vuto la myopathy (kufooka kwa minofu) ndi rhabdomyolysis (kuwonongeka kwa minofu, komwe kumatha kukhala kovulaza kwambiri).
Mavuto amtunduwu amatha kuchitika ndikumwa kwambiri zipatso zam'madzi, koma atha kuchitika pang'ono. Ngati mumadya zipatso zamphesa kapena kumwa madzi amphesa ndikumutenga Lipitor, funsani dokotala kuti ndiwotani momwe angadye, kapena ngati kungakhale bwino kumwa mankhwala ena omwe sagwirizana ndi zipatso zamphesa. Crestor alibe mgwirizano wamadzi amphesa.
Crestor ndi Lipitor ali ndi machitidwe ofanana ndi mankhwala, mwachitsanzo, ndi cyclosporine, gemfibrozil, niacin, fenofibrate, colchicine, ndi mankhwala ena opha ma virus omwe amagwiritsidwa ntchito pa HIV. Kuphatikiza Crestor kapena Lipitor ndi imodzi mwa mankhwalawa kumatha kukulitsa kuchuluka kwa ma statin, zomwe zimabweretsa chiopsezo chachikulu cha myopathy ndi rhabdomyolysis. Kutengera kusakanikirana kwa mankhwala ndi mbiri / zochitika zamankhwala, dokotala angafunikire kusintha mankhwala anu kapena kusankha mankhwala ena.
Musanatenge Crestor kapena Lipitor, uzani dokotala za mankhwala onse omwe mumamwa, kuphatikizapo mankhwala, owonjezera (OTC), ndi mavitamini, kuti athe kudziwa ngati Crestor kapena Lipitor ali otetezeka kwa inu.
| Mankhwala osokoneza bongo | Gulu la mankhwala osokoneza bongo | Crestor | Lipitor |
| Cyclosporine | Wodwalitsa | Inde | Inde |
| Gemfibrozil | Mankhwala a triglycerides apamwamba | Inde | Inde |
| Mankhwala ena oteteza ku HIV | Mankhwala a HIV | Inde | Inde |
| Chinthaka | Azole antifungal | Ayi | Inde |
| Clarithromycin | Macrolide mankhwala | Ayi | Inde |
| Darolutamide | Androgen receptor inhibitors a khansa ya prostate | Inde | Ayi |
| Regorafenib | Kinase inhibitor ya khansa | Inde | Ayi |
| Warfarin | Wotsutsa | Inde | Ayi |
| Niacin | Wothandizira ku Philippines | Inde | Inde |
| Fenofibrate | Wothandizira ku Philippines | Inde | Inde |
| Colchicine | Wothandizira anti-kukoma | Inde | Inde |
| Maalox Mylanta Zolimbikitsa | Maantibayotiki | Inde | Ayi |
| Madzi amphesa | Madzi amphesa | Ayi | Inde |
| Rifampin | Mankhwala oletsa tizilombo toyambitsa matenda | Ayi | Inde |
| Njira zolerera pakamwa | Njira zolerera pakamwa | Ayi | Inde |
| Digoxin | Ma glycosides amtima | Ayi | Inde |
Machenjezo a Crestor ndi Lipitor
- Nthawi zambiri, kufooka kwa minofu ndi kuwonongeka kumatha kuchitika chifukwa cha mankhwala a statin. Izi zikhoza kuchitika ndi mlingo uliwonse koma ndizofala kwambiri ndi mlingo waukulu. Gwiritsani ntchito mosamala kwa odwala azaka zapakati pa 65 kapena kupitilira apo, odwala omwe ali ndi vuto la impso, komanso odwala omwe ali ndi hypothyroidism omwe sangathe kuwongolera. Zowopsa izi zimakulanso ngati mankhwala ena atengedwa limodzi ndi Crestor kapena Lipitor, monga fenofibrate, niacin, cyclosporine, colchicine, kapena mankhwala ena omwe amagwiritsidwa ntchito pa HIV. Ngati muli ndi ululu wosafotokozedwa wamtundu, kapena kufooka kwa minofu, kapena kukoma mtima, makamaka ngati mukumva kutopa komanso / kapena muli ndi malungo, dziwitsani dokotala nthawi yomweyo. Crestor kapena Lipitor iyenera kuyimitsidwa ngati mwawonjezera kwambiri milingo ya creatine kinase kapena mukuganiza kuti myopathy.
- Nthawi zambiri, vuto lotchedwa immune-mediated necrotizing myopathy (IMNM) limatha kuchitika kuchokera kuchipatala cha statin. Zizindikiro zimaphatikizapo kufooka kwa minofu ndi kusintha kwa ma lab.
- Odwala ayenera kukhala ndi mayeso a laby enzyme asanayambe Crestor kapena Lipitor, akamalandira chithandizo ngati pali zizindikiro zilizonse zamatenda a chiwindi, komanso / kapena pomwe dokotala akuwona kuti ndikoyenera kukayezetsa magazi. Mankhwala a Statin atha kukulitsa milingo ya AST kapena ALT. Nthawi zambiri, kulephera kwa chiwindi (koopsa kapena kosapha) kwachitika mwa odwala omwe amatenga ma statins. Crestor kapena Lipitor ayenera kuimitsidwa nthawi yomweyo ngati chiwindi chachikulu chikuchitika. Ngati muli ndi zizindikilo za kutopa, kusowa kwa njala, mkodzo wakuda, kapena khungu kapena maso achikasu, kambiranani ndi dokotala nthawi yomweyo.
- Gwiritsani ntchito Crestor kapena Lipitor mosamala kwa odwala omwe amamwa mowa wambiri.
- Gwiritsani ntchito Crestor kapena Lipitor mosamala kwa odwala omwe ali ndi mbiri ya matenda a chiwindi. Anthu omwe ali ndi matenda a chiwindi sayenera kugwiritsa ntchito Crestor kapena Lipitor.
- Kusintha kwa milingo ya glucose ndi hemoglobin A1C kumatha kuchitika ku Crestor kapena Lipitor. Kuopsa kumawonjezeka pogwiritsa ntchito ketoconazole, spironolactone, kapena cimetidine.
- Nthawi zambiri, kukumbukira kukumbukira kapena kusokonezeka kumatha kuchitika. Lumikizanani ndi zamankhwala nthawi yomweyo kuti akuwongolereni ngati inu kapena wokondedwa wanu awona kusintha kulikonse.
- Musatenge Mlingo wa Crestor kapena Lipitor mkati mwa maola 12 wina ndi mnzake.
- Crestor kapena Lipitor atha kumwedwa kapena wopanda chakudya nthawi iliyonse yamasana. Kumeza piritsi lonse.
- Crestor kapena Lipitor sayenera kugwiritsidwa ntchito pathupi chifukwa cha chiopsezo cha fetus. Osamayamwa mukamamwa Crestor kapena Lipitor.
Machenjezo owonjezera a Crestor:
- Odwala omwe amatenga anticoagulant (monga warfarin) ayenera kuyang'aniridwa asanatenge Crestor, ndipo nthawi zambiri kumayambiriro kwa chithandizo cha statin, kuti INR ikhazikike.
- Odwala omwe amatenga mankhwala ophera mavitamini okhala ndi aluminium ndi magnesium ayenera kumwa mankhwalawa osachepera maola awiri atatenga Crestor.
Zowonjezera Lipitor machenjezo:
- Kugwiritsa ntchito zipatso za manyumwa komanso / kapena madzi amphesa (opitilira 1.2 malita tsiku lililonse) kuphatikiza ndi Lipitor kumatha kuonjezera chiopsezo cha myopathy ndi rhabdomyolysis.
Mafunso omwe amafunsidwa pafupipafupi za Crestor vs. Lipitor
Crestor ndi chiyani?
Crestor ndi statin, kapena HMG-CoA reductase inhibitor, yomwe imagwiritsidwa ntchito kwambiri pochiza cholesterol. Dzinali limakhala rosuvastatin. Crestor imapezeka pamitundu yonse komanso ya generic komanso ngati piritsi.
Kodi Lipitor ndi chiyani?
Lipitor, monga Crestor, ndi mankhwala a statin omwe amagwiritsidwa ntchito pama cholesterol ambiri. Dzina lake lenileni ndi atorvastatin. Imapezeka pamitundu yamapiritsi, pamitundu yonse komanso generic.
Kodi Crestor ndi Lipitor ndi ofanana?
Crestor ndi Lipitor onse ndi ma statins. Amagwiranso ntchito chimodzimodzi ndipo amafanana. Komabe, sizofanana ndendende. Mutha kuwerenga za kusiyana kwawo pazomwe zafotokozedwa pamwambapa. Zolemba zina zomwe mwina mudamvapo zikuphatikiza Kuyanjana (pravastatin), Zocor (simvastatin), Livalo (pitavastatin), Lescol (fluvastatin), ndi Mevacor (lovastatin).
Kodi Crestor kapena Lipitor ndibwino?
Kafukufuku akuwonetsa kuti mankhwala onsewa ndi othandiza pochepetsa cholesterol (onani pamwambapa). Kafukufuku wina akuwonetsa kuti Crestor imagwira ntchito pang'ono; komabe, mankhwala onsewa ndi othandiza komanso olekerera. Funsani wothandizira zaumoyo wanu ngati imodzi mwa mankhwalawa ingakhale yoyenera kwa inu, kutengera mbiri yanu yazachipatala.
Kodi ndingagwiritse ntchito Crestor kapena Lipitor ndili ndi pakati?
Crestor kapena Lipitor sayenera kutengedwa ndi mayi wapakati. Mankhwala onsewa amatsutsana kuti agwiritsidwe ntchito panthawi yapakati. Zitha kuvulaza mwana wosabadwa. Ngati mukumwa Crestor kapena Lipitor ndikupeza kuti muli ndi pakati, lekani kutenga statin ndipo kambiranani ndi dokotala nthawi yomweyo kuti akuthandizeni.
Kodi ndingagwiritse ntchito Crestor kapena Lipitor ndi mowa?
Nthawi zambiri, ndizotetezeka kugwiritsa ntchito a mowa pang'ono mpaka pang'ono mukatenga Crestor kapena Lipitor. Komabe, ngati muli ndi vuto la chiwindi, kapena mumamwa mowa mopitirira muyeso, kambiranani ndi omwe amakuthandizani musanasakanize statin ndi mowa. Anthu omwe ali ndi matenda osachiritsika a chiwindi ayenera kupewa kumwa kwathunthu akamamwa.
Kodi Crestor ndiyotetezeka kuposa Lipitor?
Crestor ndi Lipitor onse amalekerera bwino. Mankhwala aliwonse amakhala ndi zotsatirapo, amakhala ndi zovuta zina koma zoyipa zomwe zingachitike, nazonso. Kafukufuku (onani gawo pamwambapa) awonetsa kuti mankhwala onsewa adalekerera bwino pamayesero.
Ndi zakudya ziti zomwe muyenera kuzipewa mukamamwa Crestor?
Mukatenga Crestor (kapena Lipitor), muyenera kudya chakudya chopatsa thanzi chotsika ndi mafuta okwanira komanso cholesterol.
Zakudya zina zomwe mungafune kupewa ndi nyama zamafuta, mkaka wamafuta athunthu, ndi maswiti. M'malo mwake, yang'anani pa zakudya monga zipatso, ndiwo zamasamba, mbewu zonse, nyemba, mtedza, ndi mapuloteni owonda ngati nkhuku ndi nsomba.
Ngakhale Lipitor amalumikizana ndi (kuchuluka kwake) kwa msuzi wamphesa, Crestor ndiyabwino kutenga ndi madzi amphesa.
Kodi Crestor imakupangitsani kunenepa?
Crestor sichimalumikizidwa mwachindunji ndi kunenepa. Ngati mukugwiritsa ntchito Crestor ndikuwona kusintha kwakuthupi, funsani omwe akukuthandizani.
