Eliquis vs. Xarelto: Kusiyana, kufanana, ndi zomwe zili zabwino kwa inu
Mankhwala osokoneza bongo Vs. MnzanuKuwunika kwa mankhwala osokoneza bongo & kusiyana kwakukulu | Zinthu zothandizira | Mphamvu | Kuphunzira inshuwaransi ndikufanizira mtengo | Zotsatira zoyipa | Kuyanjana kwa mankhwala | Machenjezo | FAQ
Eliquis ndi Xarelto ndi mankhwala odziwika omwe amagwiritsidwa ntchito kuthana ndi zovuta zosiyanasiyana. Mankhwala onsewa ndi anticoagulants am'kamwa omwe amadziwika m'magulu amankhwala otchedwa factor Xa inhibitors. Amagwira ntchito poletsa chinthu Xa, chomwe chimapanga thrombin, chinthu chofunikira pakupanga ma clot. Mwa kutseka factor Xa, mankhwala amachepetsa kupanga kuundana. Pitilizani kuwerenga pansipa kuti mudziwe zambiri za Eliquis ndi Xarelto.
Kodi pali kusiyana kotani pakati pa Eliquis ndi Xarelto?
Eliquis (apixaban) ndi Xarelto (rivaroxaban powder) ndi ma NOAC (ma anticoagulants amano), omwe ndi gulu la owonda magazi atsopano. Amadziwikanso kuti DOAC (molunjika anticoagulants). Mosiyana ndi Coumadin (warfarin), anticoagulant yotchuka komanso yakale, odwala omwe amatenga Eliquis kapena Xarelto safuna kuyesa magazi pafupipafupi kuti awone kuchuluka kwake. Onse awiri Eliquis ndi Xarelto amadziwika kuti factor Xa inhibitors, koma ali ndi zosiyana.
Eliquis ndi Xarelto onse amavomerezedwa ndi a FDA kuti azigwiritsa ntchito mankhwala ndipo amapezeka mu dzina la dzina lokha. Palibe generic yomwe ilipo pakadali pano ya mankhwala; komabe, Eliquis wamba ayenera kukhala ipezeka posachedwa . Eliquis amapangidwa ndi Bristol-Myers Squibb. Xarelto amapangidwa ndi Janssen Pharmaceuticals. Mankhwala onsewa amagwiritsidwa ntchito ndi akulu, ndipo mlingowo umasiyanasiyana ndi chisonyezo.
| Kusiyana kwakukulu pakati pa Eliquis ndi Xarelto | ||
|---|---|---|
| Eliquis | Xarelto | |
| Gulu la mankhwala osokoneza bongo | Factor Xa choletsa | Factor Xa choletsa |
| Chizindikiro cha Brand / generic | Mtundu | Mtundu |
| Kodi dzina lachibadwa ndi liti? | Apixaban | Rivaroxaban ufa |
| Kodi mankhwalawa amabwera mwa mawonekedwe ati? | Piritsi, phukusi loyambira | Piritsi, phukusi loyambira |
| Kodi mulingo woyenera ndi uti? | 2.5 mg kapena 5 mg kawiri pa tsiku Mlingo umasiyanasiyana ndikuwonetsa | 10 mg mpaka 20 mg kamodzi tsiku lililonse Mlingo umasiyanasiyana ndikuwonetsa |
| Kodi mankhwalawa amatenga nthawi yayitali bwanji? | Zimasintha | Zimasintha |
| Ndani amagwiritsa ntchito mankhwalawa? | Akuluakulu | Akuluakulu |
Mukufuna mtengo wabwino kwambiri pa Eliquis?
Lowani zidziwitso zamitengo ya Eliquis kuti mudziwe kuti mitengo isintha liti!
Pezani zidziwitso zamitengo
Zinthu zomwe Eliquis ndi Xarelto adachita
Eliquis ndi Xarelto ali ndi zizindikilo zingapo zomwe zikufanana-kuti achepetse chiwopsezo cha kupwetekedwa mtima ndi kudzimbidwa kwa odwala omwe ali ndi ma nonvalvular atrial fibrillation (AFib, kapena kugunda kwamtima kosasinthasintha), kupewa kwambiri vein thrombosis (DVT) mwa odwala omwe adachotsedwa mchiuno kapena mawondo, chitani DVT, chitani PE, ndikuchepetsa chiopsezo chobwereza DVT kapena PE kutsatira chithandizo choyambirira.
Kuphatikiza apo, Xarelto ili ndi ziwonetsero zina ziwiri. Xarelto itha kuteteza matenda a venous thromboembolism (VTE) ndi VTE. Xarelto atha kulembedwa kuchipatala komanso atachira odwala achikulire omwe ali pachiwopsezo chazovuta chifukwa chakulephera kuyenda komanso zina zowopsa. Komabe, Xarelto sayenera kuperekedwa kwa odwala omwe ali pachiwopsezo chachikulu chotaya magazi. Xarelto imagwiritsidwanso ntchito ndi aspirin kuti ichepetse chiopsezo cha zochitika zazikulu zamtima monga kufa, matenda amtima, komanso kupwetekedwa kwa odwala omwe ali ndi matenda a mtsempha wamagazi (CAD) kapena matenda amitsempha (PAD).
| Mkhalidwe | Eliquis | Xarelto |
| Kuchepetsa chiopsezo cha sitiroko ndi embolism mwa odwala omwe ali ndi ma nonvalvular atrial fibrillation | Inde | Inde |
| Prophylaxis of deep vein thrombosis (DVT), yomwe ingapangitse kuti pulmonary embolism (PE), mwa odwala omwe achita opaleshoni ya m'chiuno kapena mawondo | Inde | Inde |
| Chithandizo cha DVT | Inde | Inde |
| Chithandizo cha PE | Inde | Inde |
| Kuchepetsa chiopsezo chobwereza DVT ndi PE kutsatira chithandizo choyambirira | Inde | Inde |
| Prophylaxis of venous thromboembolism (VTE) and VTE-related death in hospitalization and post-hospital dischar in older odwala omwe avomerezedwa chifukwa cha matenda azachipatala omwe ali pachiwopsezo cha zovuta zamatenda chifukwa chakulephera kuyenda / zoopsa zina osati pachiwopsezo chotaya magazi | Ayi | Inde |
| Kuphatikiza ndi aspirin, kuchepetsa chiopsezo cha zochitika zazikulu zamtima: kufa kwamtima, kufa kwa myocardial infarction (MI) ndi kupwetekedwa kwa odwala omwe ali ndi matenda amitsempha yamtendere (CAD) kapena matenda amitsempha (PAD) | Ayi | Inde |
Kodi Eliquis kapena Xarelto ndiwothandiza kwambiri?
KU kuwunika ndikuwunika meta a Eliquis ndi Xarelto a acute venous thromboembolism (VTE) adatsimikiza kuti mankhwala onsewa anali othandiza chimodzimodzi koma Eliquis akhoza kukhala otetezeka. Odwala omwe amathandizidwa ndi Xarelto adatuluka magazi ambiri, akulu ndi ang'onoang'ono.
Kafukufuku wina idawunikanso Eliquis ndi Xarelto, komanso Pradaxa (anticoagulant yatsopano) ndi Coumadin (warfarin, anticoagulant yakale). Olembawo adatsimikiza kuti Eliquis anali ndi magwiridwe antchito abwino kwambiri, chitetezo, komanso kutsatira kwa odwala.
Mankhwala abwino kwa inu angadziwike kokha ndi omwe amakuthandizani pa zaumoyo, omwe angaganizire chithunzi chonse cha matenda anu, mbiri yazachipatala, ndi mankhwala ena omwe mungamwe omwe angagwirizane ndi Eliquis kapena Xarelto.
Mukufuna mtengo wabwino pa Xarelto?
Lowani zidziwitso zamitengo ya Xarelto kuti mudziwe kuti mitengo isintha liti!
Pezani zidziwitso zamitengo
Kuphunzira ndi kuyerekezera mtengo wa Eliquis vs. Xarelto
Eliquis nthawi zambiri amakhala ndi inshuwaransi ndi Medicare Part D, koma ma copays amasiyanasiyana. Mankhwala a Eliquis omwe amapereka mwezi umodzi (mapiritsi 60 a 5 mg) amatha ndalama pafupifupi $ 700 ngati mutalipira mthumba. Mutha kugwiritsa ntchito EliCis yogula khadi ya SingleCare pansi pa $ 450.
Xarelto nthawi zambiri imakhala ndi inshuwaransi ndi Medicare Part D, koma ma copays amasiyanasiyana. Mankhwala wamba a Xarelto opangira mwezi umodzi (mapiritsi 30 a 20 mg) amatha ndalama pafupifupi $ 620 pamtengo wogulitsa. Mutha kugwiritsa ntchito coupon ya SingleCare kuti mugule Xarelto pafupifupi $ 430.
| Eliquis | Xarelto | |
| Nthawi zambiri amakhala ndi inshuwaransi? | Inde | Inde |
| Nthawi zambiri amakhala ndi Medicare Part D? | Inde | Inde |
| Mlingo woyenera | # 60, 5 mg mapiritsi | # 30, 20 mg mapiritsi |
| Chitsanzo cha Medicare Part D copay | $ 19- $ 541 | $ 19- $ 508 |
| Mtengo wosakwatiwa | $ 447- $ 483 | $ 428- $ 471 |
Zotsatira zoyipa za Eliquis vs. Xarelto
Zotsatira zoyipa kwambiri zamankhwala onsewa ndizokhudzana ndi kutuluka magazi, monga kutuluka magazi m'mphuno, kupindika (kufinya), magazi mkodzo, kapena m'kamwa. Kuchuluka kwa zotsatira zoyipa zamagazi kumatha kusiyanasiyana. Kutuluka magazi nthawi zina kumatha kukhala koopsa kapena koopsa.
Zotsatira zina zomwe zingachitike ndi Eliquis ndi monga kutopa, kuchepa mphamvu, kufooka, kupuma movutikira, ndi nseru.
Zotsatira zina zomwe zimachitika ndi Xarelto zimaphatikizapo kupweteka m'mimba kapena msana, kutopa, chizungulire, kuyabwa, kuda nkhawa, kukhumudwa, ndi / kapena kusowa tulo.
Ili si mndandanda wathunthu wazovuta. Funsani omwe akukuthandizani kuti mumve zambiri pokhudzana ndi zovuta za Eliquis ndi Xarelto.
| Eliquis | Xarelto | |||
| Zotsatira zoyipa | Zoyenera? | Pafupipafupi | Zoyenera? | Pafupipafupi |
| Magazi | Inde | Zimasintha | Inde | Zimasintha |
| Kupweteka m'mimba | Inde | Zachilendo | Inde | 2.7% |
| Kutopa | Inde | Zofala | Inde | 1.7% |
| Kutaya mphamvu | Inde | Zofala | Ayi | - |
| Kufooka | Inde | Zofala | Ayi | - |
| Kupuma pang'ono | Inde | Zofala | Ayi | - |
| Ululu wammbuyo | Ayi | - | Inde | 2.9% |
| Chizungulire | Inde | Zachilendo | Inde | 2.2% |
| Kuda nkhawa | Ayi | - | Inde | 1.4% |
| Nseru | Inde | Zofala | Ayi | - |
| Matenda okhumudwa | Ayi | - | Inde | 1.2% |
| Kusowa tulo | Ayi | - | Inde | 1.6% |
| Kuyabwa | Inde | <1% | Inde | 2.2% |
Gwero: DailyMed ( Eliquis ), Zolemba Zamagetsi ( Eliquis ), Tsiku Lililonse ( Xarelto )
Kuyanjana kwa mankhwala a Eliquis ndi Xarelto
Eliquis ndi Xarelto amalumikizana ndi mankhwala ena omwe amapangidwanso ndi ma enzyme omwewo. Mankhwala a enzyme inhibitor akagwiritsidwa ntchito ndi Eliquis kapena Xarelto, milingo ya Eliquis kapena Xarelto mthupi lanu imakulirakulira, zomwe zingakupangitseni chiwopsezo chambiri chotsika magazi. Ngati mukuyenera kumwa mankhwalawa, mwina dokotala wanu amachepetsa mlingo wanu wa Eliquis kapena Xarelto mukamamwa mankhwala onsewa.
Kumbali ina, pamene opangira ma enzyme amatengedwa ndi Eliquis kapena Xarelto, pamakhala kulumikizana komwe mankhwalawo amapangitsa Eliquis kapena Xarelto kupukusa magazi mwachangu, ndipo simudzapeza kuchuluka kwa mlingo wa Eliquis kapena Xarelto.
Komanso, kugwiritsa ntchito Eliquis kapena Xarelto ndi maanticoagulants, mankhwala opatsirana pogonana, ma NSAID (mankhwala osagwiritsa ntchito mphamvu zotsutsana ndi zotupa), ndi mankhwala ena opatsirana pogonana angapangitse ngozi yotuluka magazi.
Ili si mndandanda wathunthu wazomwe zimachitika ndi mankhwala. Funsani omwe akukuthandizani kuti mumve zambiri.
| Mankhwala osokoneza bongo | Gulu la Mankhwala | Eliquis | Xarelto |
| Chinthaka Ketoconazole Ritonavir | Enzyme inhibitors amphamvu (CYP3A4 ndi P-gp) | Inde | Inde |
| Carbamazepine Phenytoin Rifampin St. John's Wort | Olimbikitsa mavitamini amphamvu (CYP3A4 ndi P-gp) | Inde | Inde |
| Citalopram Chotsani Duloxetine Kuyanjana Fluoxetine Fluvoxamine Paroxetine Sertraline Katemera | SSRIs ndi SNRI antidepressants | Inde | Inde |
| Clopidogrel Enoxaparin Heparin NSAIDs (nthawi yayitali) ● Asipilini ● Ibuprofen ● Meloxicam ● Nabumetone ● Naproxen Warfarin (coumadin) | Maanticoagulants ndi ma antiplatelets | Inde | Inde |
Machenjezo a Eliquis ndi Xarelto
Eliquis ndi Xarelto ali ndi chenjezo la bokosi (lakuda), lomwe ndi chenjezo lamphamvu kwambiri lomwe a FDA amafunikira. Machenjezo ena ndi awa:
- Kusiya Eliquis kapena Xarelto asanakalambe kumawonjezera ngozi ya chochitika chotseka.
- Epidural kapena spinal hematoma imatha kupezeka kwa odwala omwe akulandira neuraxial (pakati pa vertebrae) anesthesia kapena kuboola msana. Hematoma imatha kubweretsa kufooka kwa nthawi yayitali kapena kwamuyaya. Chiwopsezo chimakhala chachikulu kwa odwala omwe ali ndi matenda opatsirana pogonana, odwala omwe amamwa mankhwala ena omwe amakhudza kuyenda kwa magazi, odwala omwe ali ndi mbiri yopunduka / yobwereza mobwerezabwereza, ndi / kapena odwala omwe ali ndi vuto la kufooka kwa msana kapena opaleshoni. Odwala amayenera kuyang'aniridwa pafupipafupi ngati ali ndi zizindikilo / zizindikiritso za kufooka kwa mitsempha (dzanzi / kufooka kwa miyendo, matumbo / chikhodzodzo), ndipo ngati pali vuto lililonse, wodwalayo ayenera kupita kuchipatala mwadzidzidzi.
- Kutuluka magazi kumatha kuchitika ndipo kumatha kukhala koopsa (kutulutsa magazi kwakukulu) kapena koopsa. Kugwiritsa ntchito Eliquis kapena Xarelto ndi mankhwala ena (anticoagulants, antiplatelet drug, NSAIDs, SSRI ndi SNRI antidepressants) kumawonjezera ngozi yakutaya magazi. Odwala omwe akutuluka magazi ayenera kupita kuchipatala mwadzidzidzi. Mankhwalawa ayenera kuyimitsidwa mwa odwala omwe ali ndi kutaya magazi kwambiri.
- Wothandizira wobwezeretsa amapezeka, kuti athetsere zovuta zakubwezeretsa kwa factor Xa.
- Eliquis kapena Xarelto sakuvomerezeka kwa odwala omwe ali ndi ma prosthetic mtima valves.
- Eliquis kapena Xarelto sakulimbikitsidwa ngati njira ina m'malo mwa heparin pochiza koyambirira kwa odwala a PE omwe ali ndi kusakhazikika kwa hemodynamic (mantha / mtima kulephera).
- Eliquis kapena Xarelto sayenera kugwiritsidwa ntchito kwa odwala omwe ali ndi matenda a antiphospholipid (APS) omwe ali ndi ma patatu chifukwa cha chiwopsezo chowonjezereka.
- Ngati muli ndi vuto la chiwindi kapena impso, lankhulani ndi omwe amakuthandizani musanatenge Eliquis kapena Xarelto.
Kugwiritsa ntchito mimba:
- Pali zochepa pazogwiritsira ntchito Eliquis kapena Xarelto ali ndi pakati. Chithandizo ndi Eliquis kapena Xarelto chitha kuwonjezera chiopsezo chotaya magazi nthawi yonse yoyembekezera komanso yobereka, ndikuwonjezera kutaya magazi m'mimba mwa mwana / khanda. Kugwiritsa ntchito Eliquis kapena Xarelto panthawi yobereka kapena yobereka mwa amayi omwe akulandira matenda am'mimba kumatha kuyambitsa matenda am'mimba kapena msana hematoma A anticoagulant ofupikira atha kugwiritsidwa ntchito ngati pakufunika kutero. Funsani OB-GYN wanu za kugwiritsa ntchito Eliquis kapena Xarelto panthawi yapakati. Nthawi zambiri, mankhwalawa amangogwiritsidwa ntchito ngati maubwino amapitilira zoopsa (mwachitsanzo, pathupi lina lomwe lili pachiwopsezo), ndikuwunika mosamala. Ngati mukugwiritsa ntchito kale Eliquis kapena Xarelto ndikupeza kuti ndinu woyembekezera , funsani OB-GYN wanu kuti akuwongolereni.
Mafunso omwe amafunsidwa pafupipafupi za Eliquis vs. Xarelto
Eliquis ndi chiyani?
Eliquis ndi dzina la anticoagulant (magazi ochepera magazi) omwe amagwiritsidwa ntchito kupewa kapena kuchiza magazi.
Xarelto ndi chiyani?
Xarelto ndi dzina la anticoagulant, ndipo limathandiza kupewa kapena kuchiza magazi.
Kodi Eliquis ndi Xarelto ndi ofanana?
Eliquis ndi Xarelto onse amadziwika kuti factor Xa inhibitors. Ndi ofanana kwambiri, koma osafanana ndendende. Kusiyana kwafotokozedwa pamwambapa. Zina zomwe Xa inhibitors ndi Pradaxa (dabigatran), Arixtra (fondaparinux), Savaysa (edoxaban), ndi Bevyxxa (betrixaban).
Kodi Eliquis kapena Xarelto ali bwino?
Kafukufuku (onani pamwambapa kuti mumve zambiri) awonetsa kuti Eliquis ndi Xarelto ndiwofanananso ogwira ntchito, kapena kuti Eliquis atha kukhala wogwira ntchito pang'ono. Eliquis akuwoneka kuti ali ndi chiopsezo chotsika magazi kwambiri kuposa Xarelto. Funsani dokotala ngati Eliquis kapena Xarelto ali woyenera kwa inu.
Kodi ndingagwiritse ntchito Eliquis kapena Xarelto ndili ndi pakati?
Nthawi zambiri, Eliquis ndi Xarelto sagwiritsidwa ntchito pathupi. Komabe, kusiyanasiyana kwina kumatha kuchitika kwa odwala ena omwe ali pachiwopsezo chachikulu chotseka magazi. Funsani wothandizira zaumoyo wanu.
Kodi ndingagwiritse ntchito Eliquis kapena Xarelto ndi mowa?
Mowa ungachepetse magazi. Mukatenga Eliquis kapena Xarelto ndikumwa mowa, izi zitha kuwonjezera ngozi yakutaya magazi. Komanso mowa umakulitsa matenda ena. Mutha kufunsa omwe amakuthandizani ngati ali oyenera kumwa, komanso kuchuluka kwake, ndi mankhwala omwe mumamwa komanso matenda omwe muli nawo.
Kodi Xarelto ndi yotsika mtengo kuposa Eliquis?
Pogulitsa mwezi umodzi, mtengo wa Xarelto ndi mtengo wa Eliquis ndizofanana kwambiri. Mtengo wa Eliquis ndi Xarelto wokhala ndi coupon ya SingleCare umayamba pa $ 447 ndi $ 428. Generic ya Eliquis iyenera kupezeka posachedwa.
Kodi magazi ochepetsetsa kwambiri ndi ati?
Ochepetsa magazi amakhala otetezeka akagwiritsidwa ntchito monga momwe akunenera. Komabe, ndikachepetsa magazi aliwonse, pamakhala chiopsezo chotaya magazi, ngakhale magazi akulu kapena owopsa. Opaka magazi amathanso kuyanjana ndi mankhwala ena. Funsani wothandizira zaumoyo wanu kuti mudziwe kuti ndi magazi ati omwe ndi oyenera kwambiri kwa inu.
Kodi Eliquis imakhudza chiwindi?
Ochepera 1% ya odwala pa Eliquis m'mayesero azachipatala adayesedwa modabwitsa pachiwindi. Muyenera kudziwitsa dokotala musanatenge Eliquis kapena Xarelto ngati muli ndi vuto la chiwindi.
