Humalog vs. Novolog: Kusiyana, kufanana, ndi zomwe zili zabwino kwa inu
Mankhwala osokoneza bongo Vs. MnzanuKuwunika kwa mankhwala osokoneza bongo & kusiyana kwakukulu | Zinthu zothandizira | Mphamvu | Kuphunzira inshuwaransi ndi kufananiza mtengo | Zotsatira zoyipa | Kuyanjana kwa mankhwala | Machenjezo | FAQ
Anthu mamiliyoni ambiri aku America omwe ali ndi matenda a shuga amagwiritsa ntchito insulini pafupipafupi, kaya ndi mtundu wa 1 wa shuga, mtundu wachiwiri wa shuga, kapena matenda ashuga obereka. Insulins monga Humalog ndi Novolog ndiyofunikira kuwongolera shuga wamagazi mwa omwe ali ndi matenda ashuga. Koma pali kusiyana kotani pakati pa mankhwala a insulin?
Humalog ndi Novolog ndi ma insulini othamanga mwachangu omwe amagwira ntchito mwachangu komanso kwakanthawi kochepa poyerekeza ndi ma insulini ena. Amatha kuperekedwa asanadye kuti athetse shuga wamagazi kapena mosalekeza tsiku lonse ndi pampu ya insulini. Insulini imagwira ntchito poonjezera kuchuluka kwa shuga m'maselo amthupi kuti mukhale ndi mphamvu. Shuga (shuga) ndikofunikira pakupanga mphamvu komanso magwiridwe antchito amthupi.
Humalog ndi Novolog atha kugwira ntchito chimodzimodzi. Koma sizosinthana. Kutanthauza, chimodzi sichingasinthidwe chimzake. Izi ndichifukwa choti ali ndi zosiyana pamomwe amaperekera ndikugwiritsiridwa ntchito.
Kodi pali kusiyana kotani pakati pa Humalog ndi Novolog?
Humalog ndi analog yothamanga kwambiri ya insulini yomwe idavomerezedwa ndi FDA mu 1996. Imafanana ndi insulin yamunthu yomwe ili ndi mankhwala ofanana. Humalog, yomwe imadziwikanso ndi dzina loti insulin lispro, imapezeka ngati yankho la jakisoni pansi pa khungu (subcutaneous).
Humalog insulin imabwera mu 10 mL ndi 3 mL mitsuko yamiyeso yambiri komanso 3 mL makatiriji ndi zolembera zodzaza kale (Humalog KwikPen, Humalog Tempo Pen, Humalog Junior KwikPen). Mitundu yonse ya Humalog ili ndi mayunitsi 100 / mL (U-100) a insulin kupatula Humalog KwikPen, yomwe imabweranso mu 200 mayunitsi / mL (U-200).
Novolog ndi dzina lodziwika bwino la insulini lotchedwa insulin aspart. Ndi mankhwala ofanana ndi insulin yamunthu nthawi zonse kupatula ngati ili ndi aspartic acid m'malo mwa proline amino acid mu gawo la DNA yake. Novolog idavomerezedwa ndi FDA mu 2000.
Monga Humalog, Novolog imapezeka ngati 10 ml ya vial multi-vial kwa odwala kapena othandizira kuti ajambule ndi sirinji yawo. Novolog imabweranso mu 3 mL cartridge (PenFill cartridges) ndi zolembera zodzaza kale (Novolog FlexPen, Novolog FlexTouch). Mitunduyi imakhala ndi magawo 100 / ml ya insulini ya insulini.
| Kusiyana kwakukulu pakati pa Humalog ndi Novolog | ||
|---|---|---|
| Zolemba | Novolog | |
| Gulu la mankhwala osokoneza bongo | Insulini | Insulini |
| Chizindikiro cha Brand / generic | Ma brand ndi generic amapezeka | Ma brand ndi generic amapezeka |
| Kodi dzina lachibadwa ndi liti? | Jekeseni wa lispro lispro | Jekeseni wa insulini ya insulini |
| Kodi mankhwalawa amabwera mwa mawonekedwe ati? | Njira yothetsera jakisoni wocheperako | Njira yothetsera jakisoni wocheperako |
| Kodi mulingo woyenera ndi uti? | Mlingo wa insulini umasinthasintha kwambiri ndipo umayenera kutsimikizika kutengera momwe munthu aliri, zakudya zake, komanso momwe amakhalira. Insulini yogwira mwachangu nthawi zambiri imaperekedwa kawiri kapena kanayi tsiku lililonse musanadye kapena mutatha kudya muyezo wa 0,5 mpaka 1 unit / kg / tsiku. | |
| Kodi mankhwalawa amatenga nthawi yayitali bwanji? | Matenda ashuga ndi matenda omwe amapita patsogolo omwe nthawi zambiri amafuna kuti azisamalira insulini nthawi zonse. | |
| Ndani amagwiritsa ntchito mankhwalawa? | Akuluakulu omwe ali ndi matenda a shuga amtundu wa 2 Akuluakulu ndi ana azaka zitatu kapena kupitilira apo omwe ali ndi matenda a shuga amtundu wa 1 | Akuluakulu omwe ali ndi matenda amtundu wa Type 2 Akuluakulu ndi ana azaka ziwiri kapena kupitilira apo omwe ali ndi matenda a shuga amtundu wa 1 |
Zomwe zimathandizidwa ndi Humalog ndi Novolog
Humalog ndi Novolog onse ndi mitundu ya ma insulin omwe amaperekedwa kuti athetse shuga m'magazi mwa anthu omwe ali ndi matenda ashuga. Ma insulins othamanga kwambiri amaloledwa kuchiza iwo omwe ali ndi mtundu wa 1 kapena Type 2 shuga.
Humalog ndi Novolog amagwiritsidwanso ntchito ngati mankhwala osagwiritsidwa ntchito pochiza matenda ashuga, kapena matenda ashuga omwe amapezeka mwa amayi apakati. Amayi omwe ali pachiwopsezo cha matenda ashuga amatha kukumana nawo matenda ashuga pa mimba. Insulins ngati Humalog ndi Novolog imagwiritsidwanso ntchito pochiza matenda ashuga ketoacidosis, vuto lalikulu lomwe lingachitike misinkhu ketone mkulu mwa iwo omwe ali ndi matenda a shuga a mtundu woyamba — ndipo, kawirikawiri, ndi mtundu wachiwiri wa shuga.
| Mkhalidwe | Zolemba | Novolog |
| Type 1 shuga | Inde | Inde |
| Type 2 matenda ashuga | Inde | Inde |
| Matenda a shuga | Kutumiza | Kutumiza |
| Matenda a shuga ketoacidosis | Kutumiza | Kutumiza |
Kodi Humalog kapena Novolog ndiyothandiza kwambiri?
Humalog ndi Novolog zimapereka zotsatira zoyipa mukamagwiritsidwa ntchito moyenera. Insulini iyenera kuperekedwa ngati jakisoni m'mimba, ntchafu, mikono yakumtunda, kapena matako. Humalog ndi Novolog onse amagwiranso ntchito pochepetsa shuga m'magazi.
Ngakhale ma insulini onsewa amagwira ntchito mwachangu, Novolog imagwira ntchito mwachangu pang'ono kuposa Humalog. Novolog itha kubayidwa mkati mwa mphindi zisanu mpaka 10 musanadye chakudya pomwe Humalog iyenera kubayidwa mkati mwa mphindi 15 musanadye.
Poyerekeza ndi mitundu ina ya insulini, ma insulini othamanga mwachangu atha kukhala njira zabwino zikagwiritsidwa ntchito poletsa shuga musanadye kapena mutadya. Pakuwunika meta kuchokera Thandizo la Shuga , ofufuza adapeza kuti insulin yomwe imagwira ntchito mwachangu imagwira ntchito kwambiri ngati nthawi yachakudya ya insulin ya Type 1 shuga poyerekeza ndi insulin yokhazikika. Ma insulins ochita zinthu mwachangu adapezekanso kuti akusintha Mulingo wa HbA1c bwino kwambiri mwa anthu omwe ali ndi matenda a shuga amtundu woyamba.
Kaya mwapatsidwa Humalog, Novolog, kapena mtundu wina wa insulini zimadalira momwe mulili. Funsani wothandizira zaumoyo kuti akupatseni insulini yabwino kwambiri.
Kuphatikiza ndi kuyerekezera mtengo wa Humalog vs. Novolog
Humalog ndi Novolog amapezeka pamitundu ndi mitundu ya generic. Zina, koma sizinthu zonse za Medicare Part D zomwe zimafikira insulini pokhapokha ikapatsidwa insulini. Insulini ikafunika kutumizidwa ndi mpope wa insulini, Medicare Part B ikhoza kulipira mtengo wake. Fufuzani ndi mapulani anu a inshuwaransi kuti muwone zomwe zaphimbidwa komanso mtengo wake wakuthumba womwe ungakhale.
Ngakhale pulogalamu yanu ya inshuwaransi ikuphimba insulini, mutha kusunga zambiri ndi khadi la SingleCare. Mtengo wa generic Humalog umatha kukhala $ 300. Ndi coupon ya SingleCare, pafupifupi $ 145. Momwemonso, coupon ya Novolog ikhoza kuchepetsa mtengo kuchoka pa $ 300 kufika $ 150 pa 10 ml vial. Kumbukirani, mitengo ya insulin imatha kusiyanasiyana pakati pa mabotolo ndi ma cartridge.
| Zolemba | Novolog | |
| Nthawi zambiri amakhala ndi inshuwaransi? | Zitha kuphimbidwa; zimatengera dongosolo la inshuwaransi | Zitha kuphimbidwa; zimatengera dongosolo la inshuwaransi |
| Nthawi zambiri amadzazidwa ndi Medicare? | Zitha kuphimbidwa; zimatengera dongosolo la inshuwaransi | Zitha kuphimbidwa; zimatengera dongosolo la inshuwaransi |
| Mlingo woyenera | 10 mL vial (mlingo umasiyanasiyana) | 10 mL vial (mlingo umasiyanasiyana) |
| Wopanga Medicare wamba | $ 318 | $ 335 |
| Mtengo wosakwatiwa | $ 140- $ 150 | $ 146- $ 155 |
Zotsatira zoyipa za Humalog vs. Novolog
Zotsatira zoyipa kwambiri za Humalog zimaphatikizapo kupweteka mutu, nseru, kutsegula m'mimba, kupweteka m'mimba (kupweteka m'mimba), zilonda zapakhosi (pharyngitis), mphuno (rhinitis), ndi kufooka kwa minofu (asthenia).
Zotsatira zoyipa kwambiri za Novolog zimaphatikizapo kupweteka mutu, mseru, kutsegula m'mimba, kupweteka m'mimba, rhinitis, kupweteka pachifuwa, komanso kusokonezeka kwamalingaliro.
Zotsatira zina zoyipa za insulini zimatha kuphatikizira kupweteka kwanuko, kuwotcha, kuyabwa, kapena kukwiya mozungulira tsamba la jakisoni. Zotsatira zoyipa zambiri ndizofatsa. Komabe, zovuta zowopsa zimatha kupezeka mwa iwo omwe amazindikira kusakaniza kwa insulin.
| Zolemba | Novolog | |||
| Zotsatira zoyipa | Zoyenera? | Pafupipafupi | Zoyenera? | Pafupipafupi |
| Mutu | Inde | 24% | Inde | 12% |
| Nseru | Inde | 5% | Inde | 7% |
| Kutsekula m'mimba | Inde | 7% | Inde | 5% |
| Kuwawa kwam'mimba | Inde | 6% | Inde | 5% |
| Chikhure | Inde | 27% | Ayi | N / A |
| Mphuno yothamanga | Inde | makumi awiri% | Inde | 5% |
| Minofu kufooka | Inde | 6% | Ayi | N / A |
| Kupweteka pachifuwa | Ayi | N / A | Inde | 5% |
| Kusokonezeka kwadzidzidzi | Ayi | N / A | Inde | 9% |
Izi sizingakhale mndandanda wathunthu wazovuta zomwe zingachitike. Chonde onani dokotala wanu kapena wothandizira zaumoyo kuti mudziwe zambiri.
Gwero: DailyMed ( Zolemba ), Tsiku Lililonse ( Novolog )
Kuyanjana kwa mankhwala a Humalog vs. Novolog
Humalog ndi Novolog insulin amatha kulumikizana ndi mankhwala osiyanasiyana. Maantibayotiki, monga glipizide kapena glyburide, nthawi zina amagwiritsidwa ntchito limodzi ndi insulin kuthandiza kuchepetsa magazi. Komabe, kugwiritsa ntchito mankhwalawa ndi insulin kumathandizanso kuti chiwopsezo cha shuga wambiri wamagazi, kapena hypoglycemia, chiwonjezeke.
Corticosteroids monga prednisone kapena dexamethasone imatha kukulitsa milingo ya shuga m'magazi. Chifukwa chake, kumwa mankhwalawa kumatha kuchepetsa zotsatira za insulin. Kumwa mankhwala monga antipsychotic kapena diuretics kungachepetsenso zotsatira za insulin ndikuwonjezera kukana kwa insulin. Mlingo wa insulin ungafunike kusintha mukamamwa mankhwala enawa.
Beta-blockers amatha kusintha zovuta za insulin. Kuphatikiza apo, beta-blockers amatha kubisa zizindikiro za hypoglycemia zomwe zimatha kuchitika mutamwa mankhwala olakwika a insulin. Izi zitha kupanga zoopsa zomwe zimafunika kuyang'aniridwa.
Uzani dokotala wanu za mankhwala aliwonse omwe mukumwa kuti musagwiritse ntchito mankhwala osokoneza bongo.
| Mankhwala osokoneza bongo | Gulu la mankhwala osokoneza bongo | Zolemba | Novolog |
| Glipizide Glyburide Gulu Wobwezeretsanso | Mankhwala oletsa matenda a shuga | Inde | Inde |
| Prednisone Zamgululi Dexamethasone | Corticosteroids | Inde | Inde |
| Clozapine Olanzapine | Mankhwala oletsa antipsychotic | Inde | Inde |
| Hydrochlorothiazide Chlorthalidone | Okodzetsa | Inde | Inde |
| Zamgululi Nadolol Zolemba | Beta-blockers | Inde | Inde |
* Funsani katswiri pa zamankhwala ena.
Machenjezo a Humalog ndi Novolog
Nthawi zonse pamakhala chiopsezo cha hypoglycemia mukamagwiritsa ntchito insulins monga Humalog kapena Novolog. Zizindikiro za shuga wotsika kwambiri zimatha kukhala ndi nseru, njala, chisokonezo, ndi kufooka. Pachifukwa ichi, tikulimbikitsidwa kunyamula mapiritsi a shuga kuti athandize kuthana ndi izi zomwe zitha kupha moyo. Thandizo la mankhwala ena liyenera kugwirizanitsidwa mosamala kuti insulini iyambe kuperekedwa.
Muyenera kupewa kugwiritsa ntchito Humalog kapena Novolog ngati muli ndi chidwi ndi chilichonse mwazomwe zimagwiritsidwa ntchito. Zochita za Hypersensitivity zimatha kuphatikizira mwamphamvu kapena kupuma movutikira (anaphylaxis).
Masirinji, zolembera zolembedweratu, ndi makatiriji sayenera kugawidwa ndi anthu ena omwe ali ndi matenda ashuga. Kugwiritsira ntchito chipangizo cha insulini cha wina kungakuike pachiwopsezo chachikulu chotenga kachilombo ka HIV.
Funsani omwe amakuthandizani pa zaumoyo kuti akuwonetseni potengera insulin.
Mafunso omwe amafunsidwa pafupipafupi za Humalog vs. Novolog
Kodi Humalog ndi chiyani?
Humalog ndi mawonekedwe achangu a insulin omwe amagwiritsidwa ntchito poletsa shuga m'magazi mwa omwe ali ndi matenda ashuga. Ndi FDA yovomerezedwa kuchiza matenda a shuga amtundu wa 2 mwa akulu komanso mtundu wa 1 shuga mwa akulu ndi ana azaka zitatu kapena kupitilira apo. Humalog ndi dzina la insulin lispro.
Novolog ndi chiyani?
Novolog ndi mawonekedwe a insulini othamanga kwambiri omwe amatha kuwongolera shuga m'magazi mwa anthu omwe ali ndi matenda ashuga. Ndi FDA yovomerezedwa kuti ichiritse mtundu wa 2 shuga mwa akulu komanso mtundu wa 1 shuga mwa akulu ndi ana azaka 2 kapena kupitirira. Novolog ndi dzina la insulin aspart.
Kodi Humalog ndi Novolog ndizofanana?
Ayi, Humalog ndi Novolog sizofanana. Amakhala ndimapangidwe osiyana pang'ono, zoletsa zaka, komanso mtengo wogwiritsidwa ntchito.
Kodi Humalog kapena Novolog ndiyabwino?
Humalog ndi Novolog onse ndi othandiza kutsitsa magazi m'magazi. Komabe, Novolog imagwira ntchito mwachangu pang'ono kuposa Humalog. Poyerekeza ndi ma insulins omwe amakhala nthawi yayitali ngati Lantus (insulin glargine), ma insulini othamanga mwachangu amakhala oyenera kuwongolera kuchuluka kwa shuga wamagazi musanadye komanso pambuyo chakudya. Funsani wothandizira zaumoyo kuti akupatseni insulini yabwino kwambiri yokhudza matenda anu.
Kodi ndingagwiritse ntchito Humalog kapena Novolog ndili ndi pakati?
Malinga ndi Bungwe la American Diabetes Association , insulin ndiye njira yoyamba yothanirana ndi matenda a shuga mukakhala ndi pakati. Sizinapezeke kuti zadutsa placenta. Choncho, zimaonedwa kuti ndi zotetezeka kuti zigwiritsidwe ntchito panthawi yoyembekezera.
Kodi ndingagwiritse ntchito Humalog kapena Novolog ndi mowa?
Mowa uyenera kupewedwa mukamagwiritsa ntchito insulin. Izi ndichifukwa choti mowa umatha kuonjezera kutsika kwa shuga m'magazi chifukwa cha insulin komanso Zomwe zingayambitse hypoglycemia .
Kodi pali kusiyana kotani pakati pa insulin lispro ndi insulin aspart?
Insulin lispro ndi insulin aspart ndi mitundu iwiri ya insulin yomwe imagwira ntchito mwachangu. Komabe, ndizosiyana ndimankhwala mwanjira zosiyanasiyana. Insulin lispro imagwira ntchito mkati mwa mphindi 15 pomwe insulini ya insulin imagwira ntchito mkati mwa mphindi zisanu mpaka 10. Insulini imodzi imatha kutsika mtengo kuposa inayo kutengera dongosolo lanu la inshuwaransi.
Kodi insulin imafanana ndi NovoLog?
Novolog ndi ofanana ndi ma insulins ena othamanga kwambiri monga Humalog (insulin lispro) ndi Apidra (insulin glulisine). Chifukwa chofulumira kuchitapo kanthu, Novolog, Humalog, ndi Apidra nthawi zambiri amagwiritsidwa ntchito ngati insulini yanthawi yakudya. Amatenga mphindi zosakwana 20 kuti ayambe kugwira ntchito ndikukhala kwakanthawi pafupifupi maola anayi.
